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Correction to: Vocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation Videoendocrinology 2023 10(3): pp. 41–43; doi: 10.1089/ve.2023.0012 甲状腺射频消融术中软性纤维喉镜声带监测的修正[j] .影像内分泌杂志,2013,10(3):pp. 41-43;doi: 10.1089 / ve.2023.0012
Pub Date : 2023-09-29 DOI: 10.1089/ve.2023.0012.correx
VideoEndocrinology™Ahead of Print Open AccessCorrection to: Vocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation Videoendocrinology 2023 10(3): pp. 41–43; doi: 10.1089/ve.2023.0012is erratum ofVocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency AblationPublished Online:29 Sep 2023https://doi.org/10.1089/ve.2023.0012.correxAboutSectionsPDF/EPUB Permissions & CitationsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail In the September 2023 issue of VideoEndocrinology (vol. 10, no. 3; pp. 41–43) the article entitled “Vocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation” by Valcavi R et al. requires correction.This article was originally published under the copyright of Mary Ann Liebert, Inc. publishers and American Thyroid Association. It has now been updated to reflect Open Access, with copyright transferring to the author(s), and a Creative Commons License (CC-BY) added (http://creativecommons.org/licenses/by/4.0). The CC-BY license goes into effect October 2, 2023.The online version of this article has been corrected to reflect this.FiguresReferencesRelatedDetailsRelated articlesVocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation25 Sep 2023VideoEndocrinology™ Volume 0Issue 0 InformationCopyright 2023, Mary Ann Liebert, Inc. and American Thyroid AssociationTo cite this article:Correction to: Vocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation Videoendocrinology 2023 10(3): pp. 41–43; doi: 10.1089/ve.2023.0012.VideoEndocrinology™.ahead of printhttp://doi.org/10.1089/ve.2023.0012.correxcreative commons licenseOnline Ahead of Print:September 29, 2023PDF download
VideoEndocrinology™提前打印开放访问纠正:声带监测柔性纤维喉镜在甲状腺射频消融视频内分泌202310 (3):pp. 41-43;doi: 10.1089/ve.2023.0012is在甲状腺射频消融过程中使用柔性光纤喉镜监测声带的错误发表在线:2023年9月29日https://doi.org/10.1089/ve.2023.0012.correxAboutSectionsPDF/EPUB权限和引用下载CitationsTrack CitationsAdd to favorites Back to Publication分享分享在facebook上推特链接在redditemail在2023年9月的视频内分泌(卷10,no. 10)。3;Valcavi R等人发表的题为“甲状腺射频消融术中使用柔性光纤喉镜监测声带”的文章需要纠正。本文最初由Mary Ann Liebert, Inc.出版商和美国甲状腺协会版权所有。它现在已经更新,以反映开放获取,版权转让给作者,并添加了创作共用许可证(CC-BY) (http://creativecommons.org/licenses/by/4.0)。CC-BY许可证将于2023年10月2日生效。为了反映这一点,本文的在线版本已经进行了更正。图参考资料相关细节相关文章柔性光纤喉镜在甲状腺射频消融期间的声带监测视频内分泌学™卷0期0信息版权所有2023,Mary Ann Liebert, Inc.和美国甲状腺协会引用这篇文章:修正:柔性光纤喉镜在甲状腺射频消融期间的声带监测视频内分泌学2023 10(3):41-43页;doi: 10.1089 / ve.2023.0012.VideoEndocrinology™。提前打印://doi.org/10.1089/ve.2023.0012.correxcreative commons licenseOnline提前打印:2023年9月29日pdf下载
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引用次数: 0
Vocal Cord Monitoring by Flexible Fiberoptic Laryngoscopy During Thyroid Radiofrequency Ablation. 甲状腺射频消融过程中使用柔性纤维喉镜监测声带。
Pub Date : 2023-09-25 eCollection Date: 2023-09-01 DOI: 10.1089/ve.2023.0012
Roberto Valcavi, Francesca Gaino, Roberto Novizio, Giuseppe Mercante

Introduction: Thermal injury to recurrent laryngeal nerve (RLN) during radiofrequency ablation (RFA) can produce temporary or permanent vocal cord paralysis.1 Hydrodissection with cold 5% glucose of "danger triangle" protects RLN during RFA.2 When RFA is performed under local anesthesia, RLN function is monitored by patients producing vocal sounds.3 Large lesions requiring longer RFAs warrant general sedation where voice cannot be assessed, therefore, an additional technique for RLN protection is advisable. Observation of passive symmetrical vocal cord movements during breathing by laryngeal ultrasonography is useful in assessing vocal cord function4; however, flexible-fiberoptic fibrolaringoscopy (FFL) is gold standard for assessing vocal cord movements,5 anticipating potential RLN damage. We report FFL monitoring during RFA under general sedation on a large thyroid nodule. FFL during RFA may detect RLN irritation and dysfunction if asymmetry in passive vocal cord movements is noted. Should asymmetry appear, RFA operator stops delivering energy and repositions electrode needle. Materials and Methods: Thyroid function tests, blood glucose, creatinine, transaminase, International-Normalized-Ratio, and electrocardiogram were performed. Operating room (OR) layout created sufficient space for ear-nose-throat (ENT) and RFA operators. An examination with a fiberscope camera demonstrated normal vocal cord adduction during phonation and abduction during breathing. The procedure was assisted by an anesthetist administering fentanyl 50 mcg, midazolam 1.5 to 5.0 mg, and propofol infusion 2 mg/(kg·h). General sedation was conducted so that reflexes were attenuated but still observable. Incorporating in OR by an anesthetist who performs general sedation reduces side effects and complications.6 Ultrasonography showed a 34-mL right lobe nodule abutting on the RLN area. After sedation with propofol, the ENT specialist inserted an endoscope until the glottic plane. During calm breathing, vocal cords moved symmetrically. After obtaining anterior nodule hydrodissection from strap and sternocleidomastoid muscles with 10 mL of 2% lidocaine, posterior hydrodissection was achieved by ultrasound-guided administration of 30 mL of 5% cold glucose. Anterior and posterior hydrodissections merged, separating nodule from neck structures. The radiofrequency electrode needle was then inserted into the nodule, initially positioned in inferior nodule portion adjacent to danger triangle previously isolated by hydrodissection. Initial power was 30 watts. Moving-shot technique was used. Results: FFL was performed throughout thyroid RFA. Symmetric vocal cord movements during breathing demonstrated no RLN irritation. FFL monitoring allowed observation of natural reflexive phenomena, including swallowing. Complete nodule ablation was achieved. FFL performed post-RFA confirm

引言:射频消融术(RFA)对喉返神经(RLN)的热损伤可导致暂时性或永久性声带麻痹。1用“危险三角形”的5%冷葡萄糖进行水解剖可在RFA期间保护RLN。2在局部麻醉下进行RFA时,RLN功能由发出声音的患者监测。3需要较长RFA的大型病变需要在无法评估声音的情况下进行全身镇静,因此,建议采用额外的RLN保护技术。喉部超声观察呼吸过程中被动对称的声带运动有助于评估声带功能4;然而,柔性纤维光学纤维喉镜(FFL)是评估声带运动的黄金标准,5可预测潜在的RLN损伤。我们报告了一个大型甲状腺结节在全身镇静下RFA期间的FFL监测。如果注意到被动声带运动的不对称性,RFA过程中的FFL可能检测到RLN刺激和功能障碍。如果出现不对称,RFA操作员停止输送能量并重新定位电极针。材料和方法:进行甲状腺功能测试、血糖、肌酐、转氨酶、国际标准化比值和心电图。手术室(OR)的布局为耳鼻咽喉(ENT)和RFA操作员创造了足够的空间。纤维镜检查显示发音时声带内收正常,呼吸时声带外展正常。麻醉师给药芬太尼50,协助手术 mcg,咪达唑仑1.5至5.0 mg和丙泊酚输注2 mg/(kg·h)。进行全身镇静,使反射减弱,但仍可观察到。由执行全身镇静的麻醉师纳入手术室可以减少副作用和并发症。6超声检查显示,RLN区域有一个34mL的右叶结节。在丙泊酚镇静后,耳鼻喉科专家插入内窥镜,直到声门平面。在平静的呼吸过程中,声带对称运动。在用10 mL 2%利多卡因,通过超声引导给予30 mL的5%冷葡萄糖。前部和后部的水分离融合,将结节与颈部结构分离。然后将射频电极针插入结节,最初定位在邻近先前通过水分离隔离的危险三角形的下结节部分。初始功率为30 瓦特。采用了移动射击技术。结果:在整个甲状腺RFA中进行了FFL。呼吸过程中对称的声带运动没有显示RLN刺激。FFL监测允许观察自然反射现象,包括吞咽。结节完全消融。RFA后进行的FFL证实声带运动正常。结论:我们报告了首次在RFA期间使用FFL进行声带监测。耳鼻喉科专家很容易进行FFL,患者耐受性良好。避免危险三角形和精确的RFA针定位是防止RLN损伤的关键。如果不能完全消融,良性结节会再生7,一些作者提出了额外的手术来完成消融8,这显然会增加成本。全RFA结节消融辅助FFL监测消除了重复RFA的需要,从而降低了整体治疗成本。最后,FFL监测不会延长程序,因为它与RFA同时进行。FFL是一种有效的技术,当与水分离结合使用时,可以进一步防止RFA过程中RLN的热损伤,特别适用于大型甲状腺结节消融和专业语音用户。患者同意和许可:患者提供了FFL监测的书面同意书,并允许在RFA期间使用他的肖像和超声图像。该研究是根据2013年修订的《赫尔辛基宣言》完成的。同意遵守机构审查委员会的协议。免责声明:视频中任何仪器的表示并不表明出版商、美国甲状腺协会或作者对该产品和/或公司的任何认可。不存在相互竞争的金融利益。视频运行时间:9 分钟39 秒。
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引用次数: 0
Advantages of a Conventional Thyroidectomy Approach 传统甲状腺切除术的优点
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0030
David Goldenberg
Transoral endoscopic thyroidectomy vestibular approach is the new endoscopic approach to the thyroid. Several attempts to use the advantage of endoscopes today and improve thyroidectomy have been tried for decades. Each approach has its own peculiarities, from displacing the anterior neck scar to a less conspicuous location to unilateral approaches, longer dissection, and longer learning curves to new complications. The benefits of these new approaches still lack robust data, and time will be proof of the merit of those. No competing financial interests exist. Runtime of video: 9 mins 15 secs
经口内窥镜甲状腺切除术前庭入路是一种新的甲状腺内镜入路。几十年来,人们一直在尝试利用当今内窥镜的优势来改进甲状腺切除术。每一种入路都有自己的特点,从颈前瘢痕移位到不太明显的位置到单侧入路,更长的解剖时间,更长的学习曲线到新的并发症。这些新方法的好处仍然缺乏可靠的数据,时间将证明这些方法的优点。不存在相互竞争的经济利益。影片时长:9分15秒
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引用次数: 0
The Use and Abuse of Thyroid Hormone 甲状腺激素的使用和滥用
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0025
Victor J. Bernet, Anne R. Cappola
Introduction: Thyroid hormone, in some form, has been in use for the treatment of hypothyroidism since at least the 15th century. Although thyroid hormone therapy plays an essential role in the management of hypothyroidism, it has also been misused for more dubious indications. Materials and Methods: Authors performed a search of PubMed, the American Thyroid Association (ATA) website, to include the Thyroid History Timeline that is part of the Clark T. Sawin History Resource Center, and a general internet search to identify publications and internet postings relevant to the use and abuse of thyroid hormone. Results: Documented examples of various treatments for goiter and hypothyroidism extend back to 2700 BC when seaweed was used for the treatment of goiter. In 1475, Wang Hei, a Chinese physician, reported the use of minced thyroid as a treatment for goiter. In 1891, Dr. Murray introduced the use of thyroid extract as a therapy for myxedema. Edward Kendall, PhD, at Mayo Clinic went on to isolate thyroxine in 1914 with it becoming commercially available by 1917. T3 was later isolated by Rosalind Pitt-Rivers, PhD, and Dr. Jack Gross in 1953 becoming clinically available in 1956. Various other thyroid hormone analogues, such as D-T4 and TRIAC, later became available as well. In the late 19th century, Dr. Brown-Séquard published self-experiments on the use of gland extracts as a means to improve health and restore vitality in older age. The growing indiscriminate use of various gland extracts for dubious indications led to Dr. Edward Rynearson coining the phrase “Endocriminology,” a term further popularized by Dr. Harvey Cushing as to highlight the concern about misuse and abuse of available gland extracts. Desiccated thyroid gland extract began to be used not just for goiter and hypothyroidism but also for additional “indications” such as obesity, sterility, uterine bleeding, and even feeblemindedness to name a few. In 2013, a study of over-the-counter (OTC) supplements marketed for “thyroid support” found that 9 out of 10 products contained either active T4 and/or T3 with the majority containing clinically relevant amounts. The medical literature contains multiple reports of serious adverse outcomes from exposure to supraphysiologic quantities of thyroid hormone contained in various OTC supplements. Unfortunately, the Dietary Supplement Health and Education Act of 1994 Public Law 103-417 by the 103rd Congress precludes the Food and Drug Administration (FDA) from proactively monitoring such products with the FDA only being able to act when problems are reported with a certain herb or supplement. Conclusion: Although thyroid hormone remains a cornerstone for the treatment of hypothyroidism, its misuse and abuse continue to be a source of concern. The ATA is continuing efforts to educate both health care providers and the public on the appropriate use of thyroid hormone and potential risks with its misuse. No competing financial interests exist. Vide
至少从15世纪开始,甲状腺激素就以某种形式被用于治疗甲状腺功能减退症。虽然甲状腺激素治疗在甲状腺功能减退症的治疗中起着至关重要的作用,但它也被滥用于更多可疑的适应症。材料和方法:作者检索了PubMed,美国甲状腺协会(ATA)网站,包括甲状腺病史时间表,这是克拉克T.萨温历史资源中心的一部分,并进行了一般的互联网搜索,以确定与甲状腺激素使用和滥用有关的出版物和互联网帖子。结果:记录的各种治疗甲状腺肿和甲状腺功能减退的例子可以追溯到公元前2700年,当时海藻被用于治疗甲状腺肿。1475年,中国医生王黑报告了用甲状腺碎治疗甲状腺肿的方法。1891年,默里医生引进了甲状腺提取物作为黏液性水肿的治疗方法。1914年,梅奥诊所的爱德华·肯德尔博士继续分离甲状腺素,到1917年,甲状腺素开始商业化。T3后来由Rosalind Pitt-Rivers博士和Jack Gross博士于1953年分离出来,并于1956年用于临床。各种其他甲状腺激素类似物,如D-T4和TRIAC,后来也可用。19世纪后期,布朗-萨姆夸德博士发表了自己的实验,将腺体提取物作为一种改善老年人健康和恢复活力的手段。越来越多的人不加选择地使用各种腺体提取物来治疗可疑的疾病,这使得爱德华·瑞尼尔森博士创造了“内分泌犯罪学”这个词,这个词由哈维·库欣博士进一步推广,以强调对滥用和滥用现有腺体提取物的担忧。脱水甲状腺提取物开始不仅用于甲状腺肿和甲状腺功能减退,而且还用于其他“适应症”,如肥胖,不育,子宫出血,甚至弱智等等。2013年,一项关于“甲状腺支持”的非处方(OTC)补充剂的研究发现,10种产品中有9种含有活性T4和/或T3,其中大多数含有临床相关量。医学文献中有许多关于暴露于各种OTC补充剂中含有的超生理量甲状腺激素的严重不良后果的报道。不幸的是,第103届国会通过的1994年膳食补充剂健康和教育法公法103-417禁止食品和药物管理局(FDA)主动监测这些产品,FDA只有在报告某种草药或补充剂的问题时才能采取行动。结论:虽然甲状腺激素仍然是治疗甲状腺功能减退症的基石,但其误用和滥用仍然是一个令人担忧的问题。协会正在继续努力教育保健提供者和公众如何正确使用甲状腺激素以及滥用甲状腺激素的潜在风险。不存在相互竞争的经济利益。视频内分泌学摘要为甲状腺激素的使用和滥用视频内分泌学。这个视频的工作是由dr。Bernet和Cappola使用的方法和材料如所述。正在提交带有请求更改的更新摘要。影片时长:10分34秒
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引用次数: 0
Advantages of TOETVA: A Remote Access Approach TOETVA的优点:一种远程访问方法
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0026
Leonardo Guimarães Rangel
Transoral endoscopic thyroidectomy vestibular approach (TOETVA) emerges as a minimally invasive surgery. Its trajectory since inception has been marked by a steady rise in publications, slightly curtailed by the COVID-19 pandemic. This surge bears testament to scholars' interest in this transformative technique. Initial studies of TOETVA showcased its safety and comparability with existing endoscopic methods. Notably, early complications, typical in pioneering endeavors, such as bruising, skin burns, and perforations, were documented. Anuong's comprehensive assessment of >200 TOETVA cases against open surgery illuminated intriguing parallels in complications and hospital stays, albeit with prolonged operative times and reduced postoperative pain. In subsequent studies with a cohort of 200 cases, TOETVA's statistical analyses showcased its risk parity with the transcervical approach, irrespective of variables such as gender, cancer, or Graves' status. The statistical outlier lay in the prolonged operative time for TOETVA, a trade-off for its distinctive benefits. Global adoption was palpable in Li et al.'s compilation up to 2022.1 This worldwide embrace was mirrored in the Brazilian experience, as numerous groups documented their journey, from initiation in a low-income setting to traversing the learning curve while safeguarding patient safety. Optical augmentation took center stage, from magnifying glasses amplifying surgeons' sight to robotic and endoscopic approaches boasting up to 10-fold optical zoom. The panorama extended into futuristic realms, as augmented reality and artificial intelligence promised to reshape thyroid surgery. Augmented reality platforms envisioned predicting parathyroids, nerves, and lymph nodes. Artificial intelligence offered real-time guidance, from shortening learning curves to identifying critical structures. In conclusion, TOETVA's adoption stands affirmed and resonates globally. Aesthetic concerns reconcile diverse populations. Magnification transcends optics, whereas robotic platforms enrich the endoscopic landscape. This landscape lays a foundation for future technologies. No competing financial interests exist. No funding was received for this article. Runtime of video: 10 mins 54 secs
经口内窥镜甲状腺前庭入路切除术(TOETVA)是一种微创手术。自成立以来,其发展轨迹的特点是出版物稳步增长,但因COVID-19大流行而略有减少。这种激增证明了学者们对这种变革技术的兴趣。初步研究表明TOETVA的安全性和与现有内镜方法的可比性。值得注意的是,早期并发症,典型的开拓性努力,如挫伤,皮肤烧伤和穿孔,记录在案。Anuong对超过200例TOETVA病例与开放手术的综合评估揭示了并发症和住院时间的有趣相似之处,尽管延长了手术时间并减少了术后疼痛。在随后的200例队列研究中,TOETVA的统计分析显示其与经宫颈入路的风险相等,而不考虑性别、癌症或Graves身份等变量。统计上的异常值在于TOETVA的手术时间延长,这是对其独特益处的权衡。在Li等人截至2022年的汇编中,全球采用是显而易见的。巴西的经验反映了这种全球接受,因为许多团体记录了他们的旅程,从低收入环境开始,到在保护患者安全的同时跨越学习曲线。光学增强技术占据了舞台的中心,从放大外科医生视力的放大镜到拥有高达10倍光学变焦的机器人和内窥镜方法。这幅全景图延伸到了未来的领域,增强现实和人工智能有望重塑甲状腺手术。增强现实平台可以预测甲状旁腺、神经和淋巴结。人工智能提供实时指导,从缩短学习曲线到识别关键结构。总之,TOETVA的采用得到了全球的肯定和共鸣。审美问题调和了不同的人群。放大超越了光学,而机器人平台丰富了内窥镜景观。这为未来的技术奠定了基础。不存在相互竞争的经济利益。本文未收到任何资助。影片时长:10分54秒
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引用次数: 0
Subtotal Sternectomy with Reconstruction for Metastatic Thyroid Carcinoma 转移性甲状腺癌的乳房次全切除术及重建
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0017
Danielle A. Kapustin, Jun Yun, Vivian Su, Samuel J. Rubin, Daniel G. Nicastri, Raja M. Flores, Mark L. Urken
Introduction: Approximately 4% of thyroid cancer patients present with bone metastases.1 Only 18.3% of those patients present with metastases to the thorax (rib and sternum).2,3 Bony metastases often correlate with increased morbidity and decreased overall survival.4 Therefore, multimodality treatment including surgical resection is often warranted. This study includes a video demonstration of a subtotal sternectomy for metastatic differentiated thyroid carcinoma and reconstruction using a composite methylmethacrylate and Prolene mesh covered with a pedicled latissimus dorsi flap. Materials and Methods: A 70-year-old woman presented with a 6.7-cm lesion involving the manubrium and sternal body. Informed consent was obtained. Her medical history included bilateral mastectomies with implant reconstruction for ductal carcinoma (2014) and a right thyroid lobectomy for a presumptive benign thyroid adenoma (2015). The right thyroid was removed with pathology analysis demonstrating recurrent well-differentiated thyroid carcinoma with features of both follicular thyroid carcinoma and follicular variant papillary thyroid carcinoma. In addition to the changes to the sternum, imaging showed a 1.4-cm nodular enhancing lesion in the right hemithyroidectomy bed. On positron emission tomography/CT, the sternal mass was intensely fluorodeoxyglucose avid. There was no evidence of additional distant metastases. Sternal biopsy demonstrated BRAF V600E positive metastatic follicular thyroid cancer. Results: This case was discussed at multidisciplinary tumor board, and consensus was for upfront surgical resection with likely adjuvant therapy. External beam radiation and radioactive iodine (RAI) therapy were recommended with possible administration of BRAF V600E inhibitors in the event of the development of an unresectable recurrence or progressive distant metastases. The patient underwent a left completion thyroidectomy to facilitate RAI, a right thyroidectomy bed mass excision, and a subtotal sternectomy extending below the fourth rib. Posterior margins of the sternal mass were positive, and the anterior margin was at risk with a clearance of 1 mm. The remainder of the margins was clear. Reconstruction was performed with methylmethacrylate and Prolene mesh, and a pedicled latissimus dorsi flap was used to cover the composite reconstruction. The patient began adjuvant proton beam radiation therapy to the sternum and anterior chest wall ~4 months later, with plans to undergo RAI. Overall, patients do well after a latissimus dorsi pedicled flap with minimal morbidity. A systematic review of donor site morbidity after latissimus dorsi flap (both pedicled and free flap) including 729 cases demonstrated little difficulty in daily activities after surgery but significant difficulty in participating in sports and art activities.5 Eight of 12 articles reported some shoulder strength weakness over time—shoulder extension, adduction, and internal rotation were commonly involved
导读:大约4%的甲状腺癌患者出现骨转移只有18.3%的患者转移到胸腔(肋骨和胸骨)。骨转移常与发病率增加和总生存率降低相关因此,包括手术切除在内的多模式治疗通常是必要的。本研究包括一段视频,演示了转移分化甲状腺癌的乳房次全切除术,并使用甲基丙烯酸甲酯和丙烯复合网片覆盖带蒂背阔肌皮瓣进行重建。材料和方法:一位70岁的女性,出现6.7厘米的病变,累及胸骨柄和胸骨体。获得知情同意。她的病史包括因导管癌行双侧乳房切除术并植入物重建(2014年),因推定为良性甲状腺腺瘤行右侧甲状腺小叶切除术(2015年)。右侧甲状腺被切除,病理分析显示复发的高分化甲状腺癌具有滤泡性甲状腺癌和滤泡变异型乳头状甲状腺癌的特征。除了胸骨的改变外,影像学显示右侧半甲状腺切除术床有一个1.4 cm的结节性强化病变。在正电子发射断层扫描/CT上,胸骨肿块呈强烈的氟脱氧葡萄糖状。没有其他远处转移的证据。胸骨活检显示BRAF V600E阳性转移性滤泡性甲状腺癌。结果:多学科肿瘤委员会对该病例进行了讨论,一致同意术前手术切除并辅以可能的辅助治疗。如果发生不可切除的复发或进展性远处转移,建议使用外束放疗和放射性碘(RAI)治疗,并可能使用BRAF V600E抑制剂。患者接受了左侧完全甲状腺切除术以促进RAI,右侧甲状腺切除术床肿块切除术和延伸至第四肋骨以下的乳房次全切除术。胸骨肿块后缘呈阳性,前缘有危险,间隙为1mm。剩下的差额是显而易见的。采用甲基丙烯酸甲酯和Prolene网片进行重建,带蒂背阔肌皮瓣覆盖复合重建。患者于4个月后开始胸骨及前胸壁辅助质子束放射治疗,并计划行RAI。总的来说,患者在背阔肌带蒂皮瓣后表现良好,发病率最低。系统回顾了729例背阔肌皮瓣(带蒂和游离皮瓣)术后供区发病情况,术后日常活动困难不大,但参加体育和艺术活动有明显困难12篇文章中有8篇报道了随着时间的推移出现肩部力量无力,通常包括肩部伸展、内收和内旋。我们使用在甲基丙烯酸甲酯上折叠的Prolene网片和覆盖背阔肌瓣,为患者创造了足够的结构支持,使其长期不受任何活动的限制。然而,术后立即给予患者胸骨预防措施:限制手臂在头顶和侧面的运动,以及限制剧烈的手臂运动。结论:这段视频显示了一例转移分化甲状腺癌患者行胸骨次全切除术,并用甲基丙烯酸甲酯、丙烯网片和带蒂背阔肌皮瓣重建。作者贡献:D.K.对调查、项目管理、观察和撰写原稿做出了贡献。J.Y.和V.S.参与了调查、项目管理、观察、写作审查和编辑。进行构思、监督、观察、撰写原稿。D.N.负责监督、调查和资源。R.F.负责监督、调查和提供资源。M.U.负责构思、方法、监督、调查、资源、写作审查和编辑。不存在相互竞争的经济利益。本研究于2023年6月16日在伦敦举行的世界甲状腺癌大会上以视频摘要的形式进行了展示。
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引用次数: 0
History of Thyroid Surgery in the Last Century 上个世纪甲状腺手术的历史
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0006
Lisa Orloff
Prior to the twentieth century, thyroid surgery was regarded as “horrid butchery” such that “no honest and sensible surgeon would ever engage in it.”1 Yet by the mid- twentieth century, thyroidectomy had become a respected, life-saving, safe, and increasingly practiced operation. From Kocher to Wells and onward into the twenty-first century, the evolution of thyroid surgery has continued, enhanced by the integration of endocrinology, genetics, immunology, physiology, technology, training, and multidisciplinary care. The ability to personalize and optimize the care of thyroid disorders has been progressively achieved through shared insights and discoveries, highlights of which are described herein. No competing financial interests exist. No funding was received for this article. Runtime of video: 10 mins
在20世纪之前,甲状腺手术被认为是“可怕的屠杀”,以至于“没有一个诚实而明智的外科医生会参与其中”。然而,到20世纪中叶,甲状腺切除术已成为一种受人尊敬的、能挽救生命的、安全的、越来越实用的手术。从Kocher到Wells,再到21世纪,甲状腺手术的发展一直在继续,并因内分泌学、遗传学、免疫学、生理学、技术、培训和多学科护理的整合而得到加强。通过分享见解和发现,个性化和优化甲状腺疾病护理的能力已逐步实现,本文将重点介绍。不存在相互竞争的经济利益。本文未收到任何资助。视频时长:10分钟
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引用次数: 0
History of Thyroid Ultrasound 甲状腺超声病史
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0027
Robert Levine, J. Woody Sistrunk
Dr. Woody Sistrunk interviews Dr. Robert Levine regarding the invited Centennial Paper: History of Thyroid Ultrasound by Dr. Levine. They discuss the early development and progression of education in thyroid ultrasound and the resultant rapid increase in the diagnosis of thyroid nodules and papillary microcarcinoma. They further review efforts to decrease overdiagnosis by development of guidelines and by certification in endocrine neck ultrasound. They conclude with a discussion of how artificial intelligence using deep convolutional neural networks is likely to aid in the interpretation of thyroid ultrasound in the future. Video Interview Summary Example #1 - https://www.liebertpub.com/doi/10.1089/ve.2023.0004 Example #2 - https://www.liebertpub.com/doi/10.1089/ve.2022.0050 No competing financial interests exist. Runtime of video: 17 mins 15 secs
伍迪·西斯特伦克博士采访罗伯特·莱文博士关于列文博士邀请的百年纪念论文:甲状腺超声史。他们讨论了甲状腺超声教育的早期发展和进展,以及由此导致的甲状腺结节和乳头状微癌诊断的迅速增加。他们进一步回顾了通过制定内分泌颈部超声指南和认证来减少过度诊断的努力。他们最后讨论了使用深度卷积神经网络的人工智能如何在未来帮助解释甲状腺超声。视频采访总结示例1 - https://www.liebertpub.com/doi/10.1089/ve.2023.0004示例2 - https://www.liebertpub.com/doi/10.1089/ve.2022.0050不存在相互竞争的经济利益。影片时长:17分15秒
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引用次数: 0
Minimally Invasive Treatments for Thyroid Nodules 甲状腺结节的微创治疗
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0028
Trevor E. Angell, James Wu
The social media editors for Thyroid, Dr. Trevor Angell, and for VideoEndocrinology, Dr. James Wu, discuss Dr. Angeliki Chorti's latest article “Minimally invasive treatments of benign thyroid nodules: a network meta-analysis of short-term outcomes.” No competing financial interests exist. Runtime of video: 13 mins 56 secs
甲状腺的社交媒体编辑Trevor Angell博士和视频内分泌学的James Wu博士讨论了Angeliki Chorti博士的最新文章“良性甲状腺结节的微创治疗:短期结果的网络荟萃分析”。不存在相互竞争的经济利益。影片时长:13分56秒
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引用次数: 0
Novel Endoscopic Transaxillary Gas Insufflation Approach Thyroidectomy Procedure 新型内镜下经腋窝充气入路甲状腺切除术
Pub Date : 2023-09-01 DOI: 10.1089/ve.2023.0008
Yang Liu, Jiazhong Wang, Shuo Chen, Gang Cao
Background: In the original axillary approach described by Ikeda et al. with three points incisions, they began by accessing the central neck region by dissecting the sternocleidomastoid muscle (SCM) off from the sternohyoid muscle. Later this approach was modified by utilizing a gasless approach that is popularized worldwide. The central neck region was accessed directly by dissociation of the sternal and clavicular heads of the SCM. However, this procedure required a 5–6 cm incision and also place a special static retractor. We modified the conventional gasless transaxillary thyroidectomy procedure to a transaxillary gas insufflation approach with shorter incisions, and a smaller flap creation area. This video is aimed to describe the step-by-step procedure of a case of modified endoscopic transaxillary gas insufflation thyroidectomy (ETGT). Case: A 43-year-old woman with a body mass index of 29.6 kg/m2 was found to have a thyroid nodule during physical examination and experienced no tracheal compression or voice changes. However, ultrasonography and CT scan revealed a 1.3 cm nodule in the left lobe of the thyroid, and several enlarged lymph nodes were also identified on the left side of the central neck region. A thyroid biopsy revealed papillary thyroid carcinoma with a mutation in the BRAF gene. Results of all routine preoperative examinations of the patient were within normal ranges. Surgery was indicated and endoscopic transaxillary thyroidectomy plus central neck dissection was chosen. The surgery began with making three incisions of endoscopic portals in the axillary region. After that, the working space was made using an ultrasonic scalpel while running CO2 insufflation. The central neck region was accessed by dissociating the sternal and clavicular heads of the SCM. The sternal heads of SCM, strap muscles, and thyroid gland were lifted by a suture that was retracted by ribbon. The vessels and the thyroid gland around the central neck region were dissociated, and the recurrent laryngeal nerve and the parathyroid glands were protected from injury. The specimen was released from the trap muscle and removed. Results: The technical aspect of the ETGT procedure with a step-by-step description is demonstrated in this video. Conclusions: Thyroidectomy is feasible to be done by this novel transaxillary thyroidectomy procedure with the advantages of shorter incisions and smaller flap creation area than the conventional gasless endoscopic thyroidectomy procedure. Authors' Contributions: Y.L. designed the procedure, conducted procedure, did the operations, and wrote the article. S.C. and J.W. conducted the procedure, acquired data, and edited the video. G.C. conducted the procedure, did the operations, and revised the article. All authors revised and approved the article for publication. Ethical Approval: The data and all the patient's information were anonymous, so the requirement for informed consent and ethical approvement was waived by the eth
背景:在Ikeda等人描述的最初的腋窝入路中,他们采用三点切口,首先通过从胸骨舌骨肌上剥离胸锁乳突肌(SCM)进入颈部中央区域。后来,这种方法通过使用在世界范围内普及的无气方法进行了修改。通过分离胸骨头和锁骨头直接进入颈部中央区域。然而,该手术需要一个5-6厘米的切口,并放置一个特殊的静态牵开器。我们将传统的经腋窝无气甲状腺切除术方法改进为经腋窝充气入路,切口更短,皮瓣创建面积更小。本视频的目的是描述一个改进的内镜下经腋窝气体注入甲状腺切除术(ETGT)的一步一步的程序。病例:43岁女性,体重指数29.6 kg/m2,体检时发现甲状腺结节,未见气管压迫或声音改变。然而,超声和CT扫描显示甲状腺左叶一个1.3 cm的结节,颈部中部左侧也发现了几个肿大的淋巴结。甲状腺活检显示乳头状甲状腺癌与突变的BRAF基因。术前各项常规检查结果均在正常范围内。手术指征及内镜下经腋窝甲状腺切除术加中央颈部清扫。手术开始时在腋窝区域切开三个内窥镜入口。之后,使用超声波手术刀制作工作空间,同时进行二氧化碳充气。通过分离SCM的胸骨和锁骨头进入中央颈部区域。将SCM、带状肌和甲状腺的胸骨头用带子拉回缝线提起。游离颈部中央周围的血管和甲状腺,保护喉返神经和甲状旁腺不受损伤。将标本从陷阱肌中释放并取出。结果:在这个视频中演示了ETGT程序的技术方面和一步一步的描述。结论:与传统的无气内镜甲状腺切除术相比,经腋窝甲状腺切除术切口短,皮瓣形成面积小,是可行的手术方法。作者贡献:Y.L.设计了程序,执行了程序,做了操作,并撰写了文章。S.C.和J.W.执行程序,获取数据,编辑视频。g。c。主持了程序,做了手术,并修改了文章。所有作者都对文章进行了修改并批准发表。伦理审批:数据和所有患者信息均为匿名,因此西安交通大学伦理委员会放弃了知情同意和伦理审批的要求。不存在相互竞争的经济利益。本文未收到任何资助。影片时长:9分25秒
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引用次数: 0
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VideoEndocrinology
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