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Sleep, Stress, and Cardiometabolic Health in Women of Childbearing Age with Overweight and Obesity. 超重和肥胖育龄妇女的睡眠、压力和心脏代谢健康。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-02-21 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2023.0138
Sarah S Farabi, Cindy Schwarz, Alicia Persaud, Amanda Gilbert, Debra Haire-Joshu, Rachel G Tabak

Background: Sleep is important for health, but its relationship to cardiometabolic health in women of childbearing age remains unclear. Furthermore, stress, unmet basic needs, and lack of physical activity may be related to disrupted sleep and poor cardiometabolic health in women of childbearing age and these relationships may differ by ethnicity. The purposes of this study were to investigate the relationship between sleep, markers of cardiometabolic health, stress, unmet basic needs, and physical activity in women of childbearing age with overweight or obesity and identify if these relationships differed between women that identified as Latino/Hispanic and non-Latino/Hispanic ethnicity.

Methods: A secondary cross-sectional analysis was conducted using baseline data from a trial that embeds healthy eating and activity into a national home visiting program, Parents as Teachers. The sample was stratified based on self-reported ethnicity (Hispanic/Latino or non-Hispanic/Latino). Pearson's and Spearman's correlations were used to determine bivariate relationships among sleep, cardiometabolic variables, stress, unmet basic needs, and physical activity.

Results: Two hundred seventy-six women, 46% of whom identified as Hispanic/Latino, were included in the analysis. Body mass index (BMI) was significantly correlated with sleep disturbance (ρ = 0.23, p = 0.01) in women who identify as Hispanic/Latino. Stress was positively related to sleep disturbance, sleep duration, and unmet needs for both groups of women. BMI was correlated with unmet basic needs in women who identified as non-Hispanic/Latino (ρ = 0.25, p = 0.01).

Conclusions: Our results suggest that sleep, stress, and basic needs are important in understanding cardiometabolic health in women of childbearing age and these relationships differ depending on ethnicity. Clinical Trial Registration Number: NCT03758638.

背景:睡眠对健康非常重要,但睡眠与育龄妇女心脏代谢健康的关系仍不清楚。此外,压力、未满足的基本需求和缺乏体育锻炼可能与育龄妇女睡眠紊乱和不良的心脏代谢健康有关,而且这些关系可能因种族而异。本研究旨在调查超重或肥胖育龄妇女的睡眠、心脏代谢健康指标、压力、未满足的基本需求和体育锻炼之间的关系,并确定这些关系在拉丁裔/西班牙裔和非拉丁裔/西班牙裔妇女之间是否存在差异:我们利用一项将健康饮食和活动纳入全国家访计划 "父母为师 "的试验中的基线数据进行了二次横断面分析。根据自我报告的种族(西班牙裔/拉丁美洲人或非西班牙裔/拉丁美洲人)对样本进行了分层。采用皮尔逊和斯皮尔曼相关性来确定睡眠、心脏代谢变量、压力、未满足的基本需求和体育锻炼之间的双变量关系:分析对象包括 276 名妇女,其中 46%为西班牙裔/拉丁裔。在西班牙裔/拉丁裔女性中,体重指数(BMI)与睡眠障碍显著相关(ρ = 0.23,p = 0.01)。压力与两组女性的睡眠障碍、睡眠时间和未满足的需求呈正相关。在非西班牙裔/拉丁美洲女性中,体重指数与未满足的基本需求相关(ρ = 0.25,p = 0.01):我们的研究结果表明,睡眠、压力和基本需求对了解育龄妇女的心脏代谢健康非常重要,这些关系因种族而异。临床试验注册号:NCT03758638:NCT03758638。
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引用次数: 0
The Association of Teen Pregnancy and Violence: A Multilevel Study in Colombia. 青少年怀孕与暴力的关系:哥伦比亚的一项多层次研究。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-30 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2021.0075
Angela Maria Ruiz-Sternberg, Maria Botero-Pinzon, María José Niño-Orrego, Angela Maria Pinzon-Rondon

Background: Colombia has a high teen pregnancy (TP) rate. In 2018, one in five pregnancies was from teen mothers between 10 and 19 years of age. While TP rates are declining globally, Colombia's TP rate decline has been particularly low, despite sexual education and contraception campaigns. Other factors must be studied to prevent TP. Colombia has a long history of violence. We aim to assess whether there is a relationship between TP and exposure to violence in Colombia.

Methods: Data from the Colombian Demographic and Health Survey 2015 and the Colombian National Department of Statistics were analyzed for association between TP and sexual violence, physical violence, physical punishment as a child, and community violence. Univariate, bivariate, multivariate, and multilevel binary logistic regression models were calculated using SPSS v.25 and HLM v.7.

Results: Fifteen percent of teens were pregnant. Emotional violence was reported by 47%, sexual harassment by 27%, physical violence by 17%, physical punishment as a child by 7%, and unwanted sex by 2%. Unwanted sex (odds ratio [OR]: 3.18, 95% confidence interval [95% CI]: 1.96-5.16), sexual harassment (OR: 2.43, 95% CI: 1.89-3.14), and physical punishment (OR: 20.30, 95% CI: 7.96-22.81) were associated with adolescent pregnancy. In unadjusted models, emotional violence was associated (OR: 1.22, 95% CI 1.06-1.40) and community violence showed a tendency (OR: 1.24, 95% CI: 0.99-1.55). Physical violence was not associated.

Conclusions: Violence exposure and particularly physical punishment, unwanted sex and sexual harassment were associated with TP incidence and should be considered risk factors for TP.

背景:哥伦比亚的少女怀孕率(TP)很高。2018 年,每五例怀孕中就有一例来自 10 至 19 岁的少女母亲。虽然全球的 TP 率都在下降,但哥伦比亚的 TP 率下降幅度特别低,尽管开展了性教育和避孕运动。必须对其他因素进行研究,以防止 TP 的发生。哥伦比亚的暴力历史由来已久。我们的目的是评估 TP 与哥伦比亚的暴力事件之间是否存在关系:我们分析了 2015 年哥伦比亚人口与健康调查(Colombian Demographic and Health Survey 2015)和哥伦比亚国家统计局(Colombian National Department of Statistics)的数据,以了解 TP 与性暴力、身体暴力、儿童时期的体罚以及社区暴力之间的关系。使用 SPSS v.25 和 HLM v.7 计算了单变量、双变量、多变量和多层次二元逻辑回归模型:15%的青少年怀孕。47%的青少年报告了情感暴力,27%的青少年报告了性骚扰,17%的青少年报告了身体暴力,7%的青少年报告了孩童时期的体罚,2%的青少年报告了意外性行为。意外性行为(几率比 [OR]:3.18,95% 置信区间 [95%CI]:1.96-5.16)、性骚扰(OR:2.43,95% CI:1.89-3.14)和体罚(OR:20.30,95% CI:7.96-22.81)与青少年怀孕有关。在未经调整的模型中,情感暴力与少女怀孕有关(OR:1.22,95% CI:1.06-1.40),而社区暴力与少女怀孕有关联(OR:1.24,95% CI:0.99-1.55)。结论:结论:暴力暴露,尤其是体罚、不想要的性行为和性骚扰与 TP 的发生率有关,应被视为 TP 的风险因素。
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引用次数: 0
Knowledge of Oral Emergency Contraception Among Pharmacy Students. 药学专业学生对口服紧急避孕药的了解。
IF 1.6 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-23 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2023.0175
Bria Nikole Blake, Samantha Bookbinder, Gweneth Lazenby, Amari Marshall, Elizabeth Weed, Michelle Meglin

Background: Access to emergency contraception is an important consideration in preventing unintended pregnancies. Inconsistent information about emergency contraceptive given to patients at retail pharmacies may limit access.

Objective: In this study, we aimed to assess pharmacy students' knowledge of oral emergency contraception.

Methods: Students in a Doctor of Pharmacy program completed a confidential survey about their knowledge of and training on oral emergency contraception. Respondents self-reported demographics included age, race, ethnicity, gender, and year in pharmacy school. The survey questions assessed student knowledge of indications, availability, side effects, and mechanisms of action of oral emergency contraception, as well as their training on emergency contraception. Chi-squared and Fisher's exact tests were used to determine if demographics influenced knowledge outcomes. A multivariate logistic regression, including age, gender, ethnicity, religion, year of training, hours of education, and source of knowledge acquisition, was used to adjust for confounding variables.

Results: Among 296 pharmacy students, 31% (92/296) completed the survey. Among respondents, 34% (31/92) showed adequate knowledge of oral emergency contraception based on four critical knowledge questions. Third- and fourth-year students were more likely to have adequate knowledge than first- and second-year students (odds ratio [OR], 2.70; confidence interval [95% CI], 1.07-6.80). Students who reported learning about emergency contraception through reading assignments were more likely to have adequate knowledge than students who did not report learning from reading assignments (OR, 2.09; 95% CI, 1.30-3.35).

Conclusions: Most pharmacy students at a single academic center did not have adequate knowledge of oral emergency contraception. These findings highlight the need for trainings to improve pharmacy student knowledge of oral emergency contraception.

背景:获得紧急避孕药具是预防意外怀孕的一个重要考虑因素。零售药店向患者提供的紧急避孕药具信息不一致可能会限制患者获得紧急避孕药具:本研究旨在评估药剂学专业学生对口服紧急避孕药的了解程度:方法:药学博士课程的学生完成了一项保密调查,内容涉及他们对口服紧急避孕药的了解和培训。受访者自我报告的人口统计数据包括年龄、种族、民族、性别和药学院就读年级。调查问题评估了学生对口服紧急避孕药的适应症、可用性、副作用和作用机制的了解,以及他们接受紧急避孕培训的情况。利用卡方检验和费雪精确检验来确定人口统计学是否会影响知识结果。采用多变量逻辑回归(包括年龄、性别、种族、宗教信仰、培训年份、教育学时和知识获取来源)来调整混杂变量:在 296 名药学专业学生中,31%(92/296)完成了调查。根据四个关键知识问题,34% 的受访者(31/92)对口服紧急避孕药有足够的了解。与一年级和二年级学生相比,三年级和四年级学生更有可能充分了解相关知识(几率比 [OR],2.70;置信区间 [95%CI],1.07-6.80)。报告通过阅读作业了解紧急避孕知识的学生比没有报告通过阅读作业了解紧急避孕知识的学生更有可能掌握足够的知识(OR,2.09;95% CI,1.30-3.35):一个学术中心的大多数药剂学学生对口服紧急避孕药的知识掌握不足。这些发现突出表明,有必要通过培训来提高药剂学学生对口服紧急避孕药的认识。
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引用次数: 0
Delays in Obtaining Abortion and Miscarriage Care Among Pregnant Persons in New York State During the COVID-19 Pandemic: The CAP Study. COVID-19 大流行期间纽约州孕妇在获得流产和流产护理方面的延误:CAP 研究。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-17 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2023.0128
Sarah Pickering, Meredith Manze, Jessie Losch, Diana Romero

Background: We sought to investigate delays obtaining abortion and miscarriage care during the COVID-19 pandemic, compared with before the pandemic, among pregnant persons in New York State (NYS).

Methods: We administered a cross-sectional survey in June-July 2020 to NYS residents aged 18-44 years who identified as female or transgender male (N = 1,525). This analysis focused on a subsample who had an abortion or miscarriage during COVID-19, were seeking an abortion at the time of the survey, or had an abortion or miscarriage before COVID-19 (n = 116). We conducted bivariate analyses to determine differences in delays to seeking or obtaining an abortion or miscarriage during versus before the pandemic, as well as consideration of abortion among those pregnant during versus before the pandemic. We also asked open-ended questions about miscarriage and abortion experiences.

Main findings: Of the 21 respondents who sought or were seeking an abortion during the COVID-19 pandemic, 76.2% (n = 16) reported experiencing a delay in obtaining abortion care, compared with 18.2% (n = 4) of those who experienced a delay before the pandemic (p < 0.001). A significantly higher proportion of respondents who were pregnant during the pandemic considered abortion, compared with those who gave birth before the pandemic (39.1% vs. 7.6%; p < 0.001). Of the 39 respondents who miscarried during the pandemic, 35.9% (n = 14) delayed care, compared with 5.9% (n = 2) before the pandemic (p < 0.01). Some respondents also commented on the difficulty of accessing miscarriage services during COVID-19 in open-ended responses.

Principal conclusions: Those who sought abortion or miscarriage care during the COVID-19 pandemic experienced significant delays in getting care. These are essential services that must be available during public health emergencies, and yet access to these services is now severely limited in many states due to the Dobbs vs. Jackson Women's Health Organization decision.

背景:我们试图调查在 COVID-19 大流行期间与大流行之前相比,纽约州(NYS)孕妇获得堕胎和流产护理的延迟情况:我们于 2020 年 6 月至 7 月对纽约州 18-44 岁、自称女性或变性男性的居民(N = 1525)进行了横断面调查。本分析主要针对在 COVID-19 期间堕胎或流产、调查时正在寻求堕胎或在 COVID-19 之前堕胎或流产的子样本(n = 116)。我们进行了双变量分析,以确定大流行期间与大流行前寻求或获得人工流产或流产的延迟差异,以及大流行期间与大流行前怀孕者考虑人工流产的差异。我们还询问了有关流产和堕胎经历的开放式问题:在 COVID-19 大流行期间寻求或正在寻求堕胎的 21 名受访者中,76.2%(n = 16)报告称在获得堕胎护理方面经历了延误,而在大流行前经历延误的受访者中,18.2%(n = 4)报告称在获得堕胎护理方面经历了延误(p n = 14),而在大流行前,5.9%(n = 2)报告称在获得堕胎护理方面经历了延误(p 主要结论:在 COVID-19 大流行期间寻求堕胎或流产护理的人在获得护理方面经历了严重的延误。这些都是在公共卫生突发事件期间必须提供的基本服务,但由于多布斯诉杰克逊妇女健康组织案的判决,目前在许多州获得这些服务的机会受到严重限制。
{"title":"Delays in Obtaining Abortion and Miscarriage Care Among Pregnant Persons in New York State During the COVID-19 Pandemic: The CAP Study.","authors":"Sarah Pickering, Meredith Manze, Jessie Losch, Diana Romero","doi":"10.1089/whr.2023.0128","DOIUrl":"10.1089/whr.2023.0128","url":null,"abstract":"<p><strong>Background: </strong>We sought to investigate delays obtaining abortion and miscarriage care during the COVID-19 pandemic, compared with before the pandemic, among pregnant persons in New York State (NYS).</p><p><strong>Methods: </strong>We administered a cross-sectional survey in June-July 2020 to NYS residents aged 18-44 years who identified as female or transgender male (<i>N</i> = 1,525). This analysis focused on a subsample who had an abortion or miscarriage during COVID-19, were seeking an abortion at the time of the survey, or had an abortion or miscarriage before COVID-19 (<i>n</i> = 116). We conducted bivariate analyses to determine differences in delays to seeking or obtaining an abortion or miscarriage during versus before the pandemic, as well as consideration of abortion among those pregnant during versus before the pandemic. We also asked open-ended questions about miscarriage and abortion experiences.</p><p><strong>Main findings: </strong>Of the 21 respondents who sought or were seeking an abortion during the COVID-19 pandemic, 76.2% (<i>n</i> = 16) reported experiencing a delay in obtaining abortion care, compared with 18.2% (<i>n</i> = 4) of those who experienced a delay before the pandemic (<i>p</i> < 0.001). A significantly higher proportion of respondents who were pregnant during the pandemic considered abortion, compared with those who gave birth before the pandemic (39.1% vs. 7.6%; <i>p</i> < 0.001). Of the 39 respondents who miscarried during the pandemic, 35.9% (<i>n</i> = 14) delayed care, compared with 5.9% (<i>n</i> = 2) before the pandemic (<i>p</i> < 0.01). Some respondents also commented on the difficulty of accessing miscarriage services during COVID-19 in open-ended responses.</p><p><strong>Principal conclusions: </strong>Those who sought abortion or miscarriage care during the COVID-19 pandemic experienced significant delays in getting care. These are essential services that must be available during public health emergencies, and yet access to these services is now severely limited in many states due to the Dobbs vs. Jackson Women's Health Organization decision.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"5 1","pages":"30-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10797165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Cesarean Section on Postpartum Fertility and Dysmenorrhea: A Retrospective Cohort Study in Japan. 剖腹产对产后生育能力和痛经的影响:日本的一项回顾性队列研究。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-12 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2023.0109
Mizuki Ohashi, Shunichiro Tsuji, Kyoko Kasahara, Ryoko Oe, Yumiko Tateoka, Takashi Murakami

Objective: To investigate the association between cesarean section (CS) and postpartum fertility and dysmenorrhea using data from a Japanese insurance registry.

Methods: This retrospective cohort study used a data set of patients registered between 2007 and 2021 in an insurance registry comprising specific employee-based health insurance companies in Japan. Of those data sets, we included data from participants who had their first recorded childbirth between 2014 and 2018. The exclusion criteria were any prior deliveries, dysmenorrhea, or complications that would affect the next pregnancy or postpartum dysmenorrhea since 2007. The occurrence of subsequent childbirth and postpartum dysmenorrhea until 2021 was compared between the CS and vaginal delivery (VD) groups using the log-rank test and Cox proportional hazards model with stratification according to age and age matching.

Results: This study included 25,984 (5,926 after age matching) and 5,926 participants in the VD and CS groups, respectively. After age matching, the rate of subsequent childbirth was 18.3% and 16.3%, and the rate of postpartum dysmenorrhea was 6.5% and 7.8% in the VD and CS groups, respectively. There were fewer subsequent childbirths in the CS group than in the VD group after age matching in the stratified Cox proportional hazards model (hazard ratio [HR] 95% confidence interval [CI]: 0.86 [0.79-0.94]). The CS group had a significantly higher risk of dysmenorrhea (HR [95% CI]: 1.18 [1.03-1.36]).

Conclusions: Although confounding might be existing, our study suggests that CS might be associated with decreased postpartum fertility and increased dysmenorrhea. The medical indications for CS should be carefully determined; post-CS women should be meticulously followed up.

目的利用日本保险登记处的数据,研究剖腹产(CS)与产后生育力和痛经之间的关系:这项回顾性队列研究使用了 2007 年至 2021 年期间在日本特定员工健康保险公司的保险登记处登记的患者数据集。在这些数据集中,我们纳入了2014年至2018年期间首次记录分娩的参与者的数据。排除标准为自 2007 年以来的任何前次分娩、痛经或影响下次怀孕的并发症或产后痛经。使用对数秩检验和根据年龄和年龄匹配分层的 Cox 比例危险模型,比较了 CS 组和阴道分娩(VD)组在 2021 年之前的后续分娩和产后痛经发生率:本研究的 VD 组和 CS 组分别有 25,984 人(年龄匹配后为 5,926 人)和 5,926 人参加。在年龄匹配后,VD 组和 CS 组的再生育率分别为 18.3% 和 16.3%,产后痛经率分别为 6.5% 和 7.8%。在分层考克斯比例危险模型中,经过年龄匹配后,CS组的后次分娩率低于VD组(危险比[HR] 95%置信区间[CI]:0.86 [0.79-0.94])。CS组发生痛经的风险明显更高(HR [95% CI]:1.18 [1.03-1.36]):尽管可能存在混杂因素,但我们的研究表明,CS 可能与产后生育能力下降和痛经增加有关。应仔细确定 CS 的医学指征,并对 CS 后的妇女进行细致的随访。
{"title":"Influence of Cesarean Section on Postpartum Fertility and Dysmenorrhea: A Retrospective Cohort Study in Japan.","authors":"Mizuki Ohashi, Shunichiro Tsuji, Kyoko Kasahara, Ryoko Oe, Yumiko Tateoka, Takashi Murakami","doi":"10.1089/whr.2023.0109","DOIUrl":"10.1089/whr.2023.0109","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between cesarean section (CS) and postpartum fertility and dysmenorrhea using data from a Japanese insurance registry.</p><p><strong>Methods: </strong>This retrospective cohort study used a data set of patients registered between 2007 and 2021 in an insurance registry comprising specific employee-based health insurance companies in Japan. Of those data sets, we included data from participants who had their first recorded childbirth between 2014 and 2018. The exclusion criteria were any prior deliveries, dysmenorrhea, or complications that would affect the next pregnancy or postpartum dysmenorrhea since 2007. The occurrence of subsequent childbirth and postpartum dysmenorrhea until 2021 was compared between the CS and vaginal delivery (VD) groups using the log-rank test and Cox proportional hazards model with stratification according to age and age matching.</p><p><strong>Results: </strong>This study included 25,984 (5,926 after age matching) and 5,926 participants in the VD and CS groups, respectively. After age matching, the rate of subsequent childbirth was 18.3% and 16.3%, and the rate of postpartum dysmenorrhea was 6.5% and 7.8% in the VD and CS groups, respectively. There were fewer subsequent childbirths in the CS group than in the VD group after age matching in the stratified Cox proportional hazards model (hazard ratio [HR] 95% confidence interval [CI]: 0.86 [0.79-0.94]). The CS group had a significantly higher risk of dysmenorrhea (HR [95% CI]: 1.18 [1.03-1.36]).</p><p><strong>Conclusions: </strong>Although confounding might be existing, our study suggests that CS might be associated with decreased postpartum fertility and increased dysmenorrhea. The medical indications for CS should be carefully determined; post-CS women should be meticulously followed up.</p>","PeriodicalId":75329,"journal":{"name":"Women's health reports (New Rochelle, N.Y.)","volume":"5 1","pages":"22-29"},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10797175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug Exposure During Pregnancy: A Case-Control Study from a Primary Care Database. 孕期药物暴露:一项来自初级保健数据库的病例对照研究。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-11 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2023.0123
Ainhoa Gomez-Lumbreras, Marta Leston Vazquez, Carles Vilaplana-Carnerero, Oriol Prat-Vallverdu, Cristina Vedia, Rosa Morros, Maria Giner-Soriano

Objective: Drug exposure during pregnancy is frequent, even more during first trimester as pregnant women might not be aware of their condition. We used available electronic health records (EHRs) to describe the use of medications during the first trimester in pregnant women and to compare drug exposure between those women who had an abortion (either elective or spontaneous) compared to those who had live births.

Materials and methods: Case-control study of abortions, either elective or spontaneous (cases), and live birth pregnancies (controls) in Sistema d'Informació per al Desenvolupament de la Investigació en Atenció Primària (Catalan Primary Health electronic health records) from 2012 to 2020. Exposure to drugs during first trimester of pregnancy was considered to estimate the association with abortion by conditional logistic regression and adjusted by health conditions and other drugs exposure.

Results: Sixty thousand three hundred fifty episodes of abortions were matched to 118,085 live birth pregnancy episodes. Cases had higher rates of alcohol intake (9.9% vs. 7.2%, p < 0.001), smoking (4.5% vs. 3.6%, p < 0.001), and previous abortions (9.9% vs. 7.8%, p < 0.001). Anxiety (30.3% and 25.1%, p < 0.001), respiratory diseases (10.6% and 9.2%, p < 0.001), and migraine (8.2% and 7.3%, p < 0.001), for cases and controls, respectively, were the most frequent baseline conditions. Cases had lower rate of drug exposure, 40,148 (66.5%) versus 80,449 (68.1%), p < 0.001. Association with abortion was found for systemic antihistamines (adjusted odds ratio [ORadj] 1.23, 95% confidence interval [CI] 1.19-1.27), antidepressants (ORadj 1.11, 95% CI 1.06-1.17), anxiolytics (ORadj 1.31, 95% CI 1.26-1.73), and nonsteroidal anti-inflammatory drugs (ORadj 1. 63, 95% CI 1.59-1.67).

Conclusions: These high rates of drug exposures during the first trimester of pregnancy highlights the relevance of informed prescription to women with childbearing potential.

目的:孕妇在怀孕期间经常接触药物,在怀孕头三个月更是如此,因为孕妇可能没有意识到自己的状况。我们利用现有的电子健康记录(EHR)来描述孕妇在妊娠头三个月的用药情况,并比较流产(选择性流产或自然流产)妇女与活产妇女的药物接触情况:病例对照研究:2012 年至 2020 年期间,对 Sistema d'Informació per al Desenvolupament de la Investigació en Atenció Primària(加泰罗尼亚初级保健电子健康记录)中的人工流产(选择性流产或自然流产)(病例)和活产妊娠(对照)进行研究。考虑到怀孕头三个月的药物暴露,通过条件逻辑回归估算与流产的关系,并根据健康状况和其他药物暴露进行调整:六万零三百五十例人工流产与 118085 例活产妊娠相匹配。病例的酒精摄入率较高(9.9% 对 7.2%,p p p p p p p adj].1.23,95% 置信区间 [CI] 1.19-1.27)、抗抑郁药(ORadj 1.11,95% CI 1.06-1.17)、抗焦虑药(ORadj 1.31,95% CI 1.26-1.73)和非甾体抗炎药(ORadj 1.63,95% CI 1.59-1.67):结论:妊娠头三个月的药物暴露率较高,这凸显了为有生育能力的妇女开具知情处方的重要性。
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引用次数: 0
The Role of Female Physicians in Psychosomatic Medicine: Opportunities and Challenges. 女医生在心身医学中的作用:机遇与挑战。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2024-01-11 eCollection Date: 2024-01-01 DOI: 10.1089/whr.2023.0070
Caroline Rometsch

Background: Female physicians are in some cases preferred by patients due to their sex-related characteristics such as softness and empathy. Psychosomatic medicine presents a compelling working environment due to its holistic approach.

Methods: This brief review synthesizes the challenges encountered by female physicians in psychosomatic medicine and outlines potential strategies for overcoming these barriers.

Results: The presence of female role models may constitute a crucial advancement in this process. There exists a pressing demand for specialized clinical and scientific programs in psychosomatic medicine at both national and international levels. Such programs, offered by universities and ministries, as well as comprehensive training initiatives, are indispensable in fostering the next generation of females in psychosomatics. Leading journals can lend their support by publishing special issues dedicated to female physicians.

Conclusion: Strengthening female physicians throughout all positions in psychosomatic medicine can contribute ultimately to the improvement of patient care.

背景:在某些情况下,女性医生因其与性别有关的特点(如温柔和同情心)而受到患者的青睐。心身医学因其整体方法而提供了一个令人信服的工作环境:这篇简短的综述总结了心身医学领域女医生遇到的挑战,并概述了克服这些障碍的潜在策略:结果:女性榜样的存在可能是这一过程中的关键进步。在国家和国际层面,对心身医学专业临床和科学课程的需求十分迫切。由大学和部委提供的此类课程以及综合培训计划对于培养下一代心身医学女性人才不可或缺。主要期刊可以通过出版女医师专刊来提供支持:结论:在心身医学的各个岗位上加强女医生的培养,最终将有助于改善对患者的护理。
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引用次数: 0
Urinary Biopyrrin Levels and Their Relationship with the Menstrual Cycle and Concomitant Symptoms Among Healthy Nonpregnant Women of Reproductive Age: A Cohort Study. 健康未孕育龄妇女尿液中生物吡咯啉水平及其与月经周期和伴随症状的关系:一项队列研究。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2023-12-28 eCollection Date: 2023-01-01 DOI: 10.1089/whr.2023.0074
Yoko Chiba, Risako Hayashi, Hidehiro Hayashi, Ting-Fang Kuo, Wataru Hojo, Takuya Iwabuchi

Background: Urinary biopyrrin (UBP) is an oxidative metabolite formed from the reaction of bilirubin with reactive oxygen species. Previous studies have explored the relationship between UBP levels and certain diseases or pregnancy. However, UBP levels in healthy nonpregnant women have not been well examined. We aimed to clarify the representative value of UBP in healthy nonpregnant women and explore its relationship with menstrual cycles and concomitant symptoms.

Methods: We included healthy, nonpregnant Japanese women aged 20-39 years with normal body mass index and menstrual cycle. In total, 1260 urine samples collected during 43 menstrual cycles of 36 women were analyzed to determine the representative values and reference intervals of UBP levels. The correlation between daily UBP levels and the order of the day was explored, and median UBP levels of 5-day clusters were compared using Friedman and Mann-Whitney U tests. These analyses were also conducted in women with concomitant symptoms during the menstrual cycle.

Results: The median UBP level in all samples was 0.2291 (reference: 0.0102-2.9335) μmol/gCr. There was no significant relationship between the median UBP level and menstrual cycle, regardless of the presence of self-manageable symptoms during or before menstruation.

Conclusions: The representative UBP value and its reference interval can serve as standards for comparison with other populations. Our findings suggest that the UBP level may be an objective oxidative stress indicator that is less sensitive to menstrual cycle and concomitant symptoms. UBP levels in healthy nonpregnant women could be assessed regardless of the menstrual cycle and concomitant symptoms.

背景:尿液中的生物卟啉(UBP)是胆红素与活性氧反应生成的一种氧化代谢物。以往的研究探讨了 UBP 水平与某些疾病或妊娠之间的关系。然而,健康非孕妇的 UBP 水平尚未得到很好的研究。我们的目的是明确UTBP在健康未孕女性中的代表性价值,并探讨其与月经周期和伴随症状的关系:我们纳入了 20-39 岁、身体质量指数和月经周期正常的健康未孕日本女性。对 36 名女性在 43 个月经周期中收集的 1260 份尿液样本进行了分析,以确定 UBP 水平的代表值和参考区间。研究人员探讨了每日膳食纤维素水平与当天顺序之间的相关性,并使用弗里德曼检验和曼-惠特尼 U 检验比较了 5 天集群的膳食纤维素水平中位数。这些分析还针对月经周期中伴有症状的妇女进行:结果:所有样本的 UBP 水平中位数为 0.2291(参考值:0.0102-2.9335)μmol/gCr。无论月经期间或月经前是否出现可自我控制的症状,UTBP 的中位数与月经周期之间均无明显关系:具有代表性的UTBP值及其参考区间可作为与其他人群进行比较的标准。我们的研究结果表明,UTBP 水平可能是一个客观的氧化应激指标,对月经周期和伴随症状的敏感性较低。无论月经周期和伴随症状如何,都可以评估健康非孕妇的UTBP水平。
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引用次数: 0
Can We Implement Multispecialty Mother-Infant Dyadic Care to Systematize Interpregnancy Services After a Preterm Birth? 我们能否在早产后实施多专科母婴联动护理,使孕产期服务系统化?
IF 1.6 Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2023-12-18 eCollection Date: 2023-01-01 DOI: 10.1089/whr.2023.0148
Seuli Bose-Brill, Shannon L Gillespie, Kartik K Venkatesh
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引用次数: 0
Integrating Care for Mother-Infant Dyads After Preterm Birth: A Qualitative Study of Clinician Perspectives on Feasibility. 早产后母婴护理一体化:临床医生对可行性看法的定性研究。
Q3 OBSTETRICS & GYNECOLOGY Pub Date : 2023-12-18 eCollection Date: 2023-01-01 DOI: 10.1089/whr.2023.0098
Emily F Gregory, Peter F Cronholm, Lisa D Levine, Rinad S Beidas, Mario P DeMarco, Ann L O'Sullivan, Scott A Lorch, Adya I Maddox, Katherine Wu, Alexander G Fiks

Objective: There are gaps in receipt of maternal preventive services in the interconception period. Yet mother-infant dyads have frequent health care visits. Health systems have opportunities to better capitalize on existing visits to address dyad needs, but this possibility has not been fully explored.

Methods: In this qualitative study we conducted semistructured interviews with clinical team members involved with birthing parents or infants after preterm birth. We conducted snowball sampling from teams in pediatrics, obstetrics, and family medicine at two geographically adjacent health systems. Interviews explored perspectives on existing barriers and facilitators to integrating dyad care across adult and infant teams. Interviews were audio-recorded, professionally transcribed, and coded using an integrated approach.

Results: We interviewed 24 physicians, nurses, midwives, and social workers (March-November 2021). Participants identified barriers to integrated care including infrequent communication between clinical teams, which was generalizable to care of the birthing parent or infant as individuals, and additional barriers related to privacy, credentialing, and visit design that were specific to dyad care. To improve integration of dyad care, clinicians proposed adapting a variety tools and procedures currently used in their practices, including electronic health record tools for communication, dedicated roles to support communication or navigation, centralized information on resources for dyad care, referral protocols, identifying dyads for proactive outreach, and opportunities for clinicians to connect face-to-face about shared patients or families.

Conclusions: Clinicians believe existing health care structures and processes can be adapted to address current substantial barriers to integrated dyad care.

目标:孕产妇在孕中期接受预防服务的情况存在差距。然而,母婴二人组却经常接受医疗服务。医疗系统有机会更好地利用现有的就诊机会来满足母婴双方的需求,但这种可能性尚未得到充分探讨:在这项定性研究中,我们对参与早产后父母或婴儿分娩的临床团队成员进行了半结构化访谈。我们从两个地理位置相邻的医疗系统的儿科、产科和家庭医学团队中进行了滚雪球式抽样。访谈从现有障碍和促进因素的角度探讨了在成人和婴儿团队中整合双亲护理的问题。我们对访谈进行了录音、专业转录,并采用综合方法进行了编码:我们采访了 24 名医生、护士、助产士和社工(2021 年 3 月至 11 月)。参与者指出了整合护理的障碍,包括临床团队之间沟通不频繁,这可以推广到分娩父母或婴儿的个人护理,以及与隐私、资格认证和就诊设计有关的其他障碍,这些都是双人护理所特有的。为了改善双亲护理的整合,临床医生建议调整他们目前在实践中使用的各种工具和程序,包括用于沟通的电子健康记录工具、支持沟通或导航的专门角色、双亲护理资源的集中信息、转诊协议、识别双亲进行主动外联,以及临床医生就共同患者或家庭进行面对面沟通的机会:临床医生认为,可以对现有的医疗结构和流程进行调整,以解决目前整合式患者护理所面临的巨大障碍。
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引用次数: 0
期刊
Women's health reports (New Rochelle, N.Y.)
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