M C Meyer, J Cloyd, W R Garnett, G L Holmes, J R Schiffer
Epilepsy is, for many patients, a lifelong condition that requires treatment with powerful drugs whose doses must be carefully titrated to avoid both breakthrough seizures and toxicity. The medication regimens used to treat epilepsy are further complicated by the fact that most seizure medications are metabolized in the liver and have the potential for serious pharmacokinetic drug-drug interactions with many other medications. Successful management of epilepsy requires a high degree of cooperation among the patient, the pharmacist, and the treating physician. Such cooperation can ensure that the appropriate treatment and drug preparation are selected, compliance is maintained, and dangerous drug-drug interactions are avoided.
{"title":"Practical considerations in anticonvulsant therapy--Part 2.","authors":"M C Meyer, J Cloyd, W R Garnett, G L Holmes, J R Schiffer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Epilepsy is, for many patients, a lifelong condition that requires treatment with powerful drugs whose doses must be carefully titrated to avoid both breakthrough seizures and toxicity. The medication regimens used to treat epilepsy are further complicated by the fact that most seizure medications are metabolized in the liver and have the potential for serious pharmacokinetic drug-drug interactions with many other medications. Successful management of epilepsy requires a high degree of cooperation among the patient, the pharmacist, and the treating physician. Such cooperation can ensure that the appropriate treatment and drug preparation are selected, compliance is maintained, and dangerous drug-drug interactions are avoided.</p>","PeriodicalId":75481,"journal":{"name":"American pharmacy","volume":"NS35 9","pages":"31-6, 40"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18493750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-09-01DOI: 10.1016/S0160-3450(15)30073-8
Pamela E. Ciummo, Norman L. Katz PhD
{"title":"Interactions and Drug-Metabolizing Enzymes","authors":"Pamela E. Ciummo, Norman L. Katz PhD","doi":"10.1016/S0160-3450(15)30073-8","DOIUrl":"10.1016/S0160-3450(15)30073-8","url":null,"abstract":"","PeriodicalId":75481,"journal":{"name":"American pharmacy","volume":"35 9","pages":"Pages 41-53"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0160-3450(15)30073-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18493753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-09-01DOI: 10.1016/S0160-3450(15)30074-X
Judith Ronshagen
{"title":"The Pharmacist's Role on the Hospital Patient Management Team","authors":"Judith Ronshagen","doi":"10.1016/S0160-3450(15)30074-X","DOIUrl":"10.1016/S0160-3450(15)30074-X","url":null,"abstract":"","PeriodicalId":75481,"journal":{"name":"American pharmacy","volume":"35 9","pages":"Pages 54-61"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0160-3450(15)30074-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18493754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-09-01DOI: 10.1016/S0160-3450(16)36998-7
Timothy R. Covington PharmD, Peter D. Hurd PhD
{"title":"From the Literature","authors":"Timothy R. Covington PharmD, Peter D. Hurd PhD","doi":"10.1016/S0160-3450(16)36998-7","DOIUrl":"https://doi.org/10.1016/S0160-3450(16)36998-7","url":null,"abstract":"","PeriodicalId":75481,"journal":{"name":"American pharmacy","volume":"35 9","pages":"Page 7"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0160-3450(16)36998-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91985906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}