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Role of the placental interface and of trophoblast/maternal tissue interactions in the survival of the murine foetal allograft. 胎盘界面和滋养细胞/母体组织相互作用在小鼠同种异体胚胎移植存活中的作用。
Annales d'immunologie
Pub Date : 1984-11-01
ChaouatG, J P Kolb, M Rivière
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引用次数: 0
Speculations on the transplantation biology of the maternal/foetal interface. 关于母体/胎儿界面移植生物学的推测。
Annales d'immunologie
Pub Date : 1984-11-01
T J Gill
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引用次数: 0
2nd Forum in Immunology: "Ir genes." Discussion. 第二届免疫学论坛:“Ir基因”。讨论。
Annales d'immunologie
Pub Date : 1984-05-01
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引用次数: 0
Immunoactive products of murine placenta. II.--Afferent suppression of maternal cell-mediated immunity by supernatants from short-term cultures of murine trophoblast-enriched cell suspensions. 小鼠胎盘免疫活性产物。2小鼠滋养层富集细胞悬浮液短期培养的上清液对母体细胞介导免疫的传入抑制。
Annales d'immunologie
Pub Date : 1984-03-01
G Chaouat, J P Kolb

Supernatants from short-term cultures of mid-term murine trophoblast cells were assayed for their in vitro regulatory potential. They markedly inhibited cell-mediated lympholysis and mixed lymphocyte reaction in a non-specific, non-restricted fashion. By contrast, the mitogenic response to optimal doses of ConA was unaffected, while the plaque-forming cell response to sheep red blood cells was either unmodified or slightly enhanced. These data suggest that placenta-derived cells secrete factors which selectively impair some cell-mediated immune responses. It is suggested that these factors play an important role in the lack of generation of cytolytic T lymphocytes towards paternal alloantigens expressed on the trophoblast during allopregnancy.

对小鼠中期滋养细胞短期培养的上清进行了体外调节潜能的测定。它们以非特异性、非限制性的方式显著抑制细胞介导的淋巴溶解和混合淋巴细胞反应。相比之下，对最佳剂量的ConA的有丝分裂反应不受影响，而斑块形成细胞对绵羊红细胞的反应要么没有改变，要么略有增强。这些数据表明，胎盘源性细胞分泌的因子选择性地损害一些细胞介导的免疫反应。这表明，这些因素在同种异体妊娠期间对滋养细胞上表达的父本同种异体抗原缺乏细胞溶解T淋巴细胞的产生中起重要作用。
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引用次数: 0
[Assay of rabbit anti-thermolabile enterotoxin antibodies from Escherichia coli by an immunoenzyme technic]. [免疫酶法测定兔大肠杆菌抗热肠毒素抗体]。
Annales d'immunologie
Pub Date : 1984-03-01
Y Germani, B Dassy, G Le Gonidec, J L Guesdon

The titration of rabbit anti-Escherichia coli heat-labile enterotoxin antibodies by an immunosorbent assay (ELISA) generally uses a GM1 coating step to lend specificity to the ELISA reaction at a time when the method is tempered by a lack of purified E. coli toxin. We have developed an adsorption method of the toxin to the polystyrene in order to simplify the technique. Three different immunosorbent preparations were tested to determine which of them yielded the most sensitive results.

利用免疫吸附试验(ELISA)测定兔抗大肠杆菌热不稳定肠毒素抗体时，通常使用GM1包被步骤，以增加ELISA反应的特异性，因为该方法由于缺乏纯化的大肠杆菌毒素而受到影响。我们开发了一种将毒素吸附到聚苯乙烯上的方法，以简化工艺。测试了三种不同的免疫吸附制剂，以确定哪一种产生了最敏感的结果。
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引用次数: 0
T cells as regulators of haematopoiesis. T细胞作为造血的调节因子。
Annales d'immunologie
Pub Date : 1984-03-01
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引用次数: 0
The idiotypes of V kappa 21 light chains. V kappa 21轻链的独特型。
Annales d'immunologie
Pub Date : 1984-01-01
K Huppi, M Julius, L Staudt, W Gerhard, M Weigert
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引用次数: 0
H-2 and non-H-2 Ir genes. H-2和非H-2 Ir基因。
Annales d'immunologie
Pub Date : 1984-01-01 DOI: 10.1007/978-1-4612-5633-5_54
E. Simpson
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引用次数: 2
Structural correlates of idiotypic determinants. 独特型决定因素的结构相关性。
Annales d'immunologie
Pub Date : 1984-01-01
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引用次数: 0
[An immunoenzyme technic for demonstrating the molecular hybridization of nucleic acids]. [用于证明核酸分子杂交的免疫酶技术]。
Annales d'immunologie
Pub Date : 1983-11-01
F Traincard, T Ternynck, A Danchin, S Avrameas

An immunoenzymatic procedure has been developed based on the use of monoclonal antibodies specific for 5-bromodeoxyuridine (BdUr). It allows the detection of BdUr-labelled DNA immobilized on a nitrocellulose filter. Using this procedure, it was possible to detect up to 0.5 pg of mammalian DNA labelled in vivo with BdUr, 5 pg of nick-translated BdUr-labelled PBR-322 and, using this latter probe and dot-blot hybridization, 50 pg of native unlabelled PBR-322.

基于5-溴脱氧尿苷(BdUr)特异性单克隆抗体的使用，开发了一种免疫酶促程序。它允许检测固定在硝化纤维素过滤器上的bdu标记的DNA。使用这种方法，可以检测到0.5 pg的BdUr标记的哺乳动物DNA, 5 pg的镍翻译BdUr标记的PBR-322，以及50 pg的原生未标记的PBR-322，使用后一种探针和斑点杂交。
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引用次数: 0
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