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The effects of manganese on aconitine-induced ventricular tachycardia. 锰对乌头碱致室性心动过速的影响。
Archivio di fisiologia
Pub Date : 1973-12-01
M Puletti, M Mariani, G F Jacobellis, G Coletti, M A Perego

Isolated rabbit heart with independent perfusion of a small left ventricular area was used to study the effect of manganese ions on aconitine-induced ventricular tachycardia. Manganese chloride 4 mM in Locke solution exhibited a constant preventive or suppressive effect versus aconitum-induced rhythm disorders. It is concluded that the interpretation of aconitine cardiotoxic effects on the sole basis of phase 3 modifications require further evidence, and that an increased diastolic depolarization rate may well explain, at least in this experimental model, the genesis of arrhythmias induced by this drug.

采用兔离体左心室小面积独立灌注心脏，研究锰离子对乌头碱致室性心动过速的影响。Locke溶液中4 mM氯化锰对乌头诱发的节律障碍具有持续的预防或抑制作用。综上所述，乌头碱对心脏毒性作用的解释仅基于3期修饰，需要进一步的证据，至少在这个实验模型中，舒张去极化率的增加可能很好地解释了乌头碱引起的心律失常的发生。
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引用次数: 0
Reflex responses of respiratory muscles to tilting and positive pressure breathing. 呼吸肌对倾斜和正压呼吸的反射反应。
Archivio di fisiologia
Pub Date : 1973-12-01
J Mortola, G Sant'Ambrogio

We have recorded the action potentials of muscle fibres of External Oblique in anaesthetized rabbits in supine and horizontal position. During head-up tilting the inspiratory activity is inhibited and the abdominal activity is excited. Both these two responses are reflexly mediated through vagal afferent fibres. The positive pressure was chosen as to determine a shift in end-expiratory volume similar to that induced by the head-up tilting. Also at positive pressure breathing (PPB) the abdominal activity increases but less than during head-up tilting. This result seems to indicate the importante of the proprioceptive afferents of the external oblique during the vertical posture. The blockade of vagal nervous conduction markedly reduces the abdominal activity both during tilting and P.P.B. and similar results are obtained either by "total" or "partial" vagal blockade. Therefore it seems possible to conclude that both these two reflexes (introduced by head-up tilting and PPB) be due to the activation of the same receptors (pulmonary stretch receptors).

我们记录了麻醉兔在仰卧位和水平位时外斜肌肌纤维的动作电位。在仰卧时，吸气活动受到抑制，腹部活动兴奋。这两种反应都是通过迷走神经传入纤维反射介导的。选择正压来确定呼气末容积的变化，类似于头部向上倾斜引起的变化。同样在正压呼吸(PPB)时，腹部活动增加，但比平头倾斜时少。这一结果似乎表明在垂直姿势时外斜肌本体感觉传入的重要性。迷走神经传导阻滞可显著降低俯卧和俯卧时的腹部活动，“完全”或“部分”迷走神经阻滞也可获得类似的结果。因此，似乎有可能得出结论，这两种反射(由抬头倾斜和PPB引入)是由于相同的受体(肺拉伸受体)的激活。
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引用次数: 0
[Study on the absorption and utilization of D-galactose and D-glucose by liver and muscular tissue in the albino rat]. [白化大鼠肝脏和肌肉组织对d -半乳糖和d -葡萄糖的吸收利用研究]。
Archivio di fisiologia
Pub Date : 1973-12-01
A Concu, F Fadda, G Liguori

In order to compare the disposition of D-galactose and D-glucose in various organs of the rat, we have measured the amount of 14C-galactose and 14C-glucose present in the enteric canal, blood, muscle and liver, 2h. after the oral administration of the labelled esoses. Our results show that the two esoses are ebsorbed almost completely and to the same extent by two hours after their administration, Galactose has a longer half-life than glucose, being more slowly utilized in the synthesis of glycogen in liver and muscle.

为了比较d -半乳糖和d -葡萄糖在大鼠各器官中的分布情况，我们测量了2h时肠管、血液、肌肉和肝脏中存在的14c -半乳糖和14c -葡萄糖的量。口服标记的esoses后。我们的研究结果表明，半乳糖和半乳糖在给药后2小时内几乎完全吸收，吸收程度相同，半乳糖的半衰期比葡萄糖长，在肝脏和肌肉中合成糖原的速度更慢。
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引用次数: 0
[Effect of localized pulmonary deformations on alveolar morphology]. 局部肺变形对肺泡形态的影响。
Archivio di fisiologia
Pub Date : 1973-06-30
E D'Angelo, S Michelini
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引用次数: 0
Cardiovascular and metabolic readjustment to isometric contraction in man. 心血管和代谢对人体等长收缩的调整。
Archivio di fisiologia
Pub Date : 1973-06-30
A Veicsteinas, L Dell'Orto, M Fumagalli, P Cerretelli
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引用次数: 0
[Susceptibility and habituation to animal hypnosis in intact and decerebrate pigeons]. [完整鸽子和失智鸽子对动物催眠的易感性和习惯化]。
Archivio di fisiologia
Pub Date : 1973-06-30
D Musumeci, M Brunelli, G Carli
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引用次数: 0
[Patterns of discharge of neurons of the posterior group of the thalamus during sleep and consciousness]. [睡眠和意识时丘脑后群神经元放电的模式]。
Archivio di fisiologia
Pub Date : 1973-06-30
F Santangelo, S Sapienza, A Urbano, A Viscuso
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引用次数: 0
Rib-cage and abdomen-diaphragm contribution to ventilation during sleep in man. 肋骨笼和腹横膈膜对人体睡眠时通气的贡献。
Archivio di fisiologia
Pub Date : 1973-06-30
J J O'Flaherty, G Sant'Ambrogio, P Mognoni, F Saibene, E Camporesi
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引用次数: 0
[Relation between the neuron discharge in the cat visual areas 17 and 18 and stationary stimulations with variable intensities of light and contrast]. [猫视觉区17和18的神经元放电与可变光强和对比度的固定刺激的关系]。
Archivio di fisiologia
Pub Date : 1973-06-30
E Riva Sanseverino, G Galletti, M G Maioli
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引用次数: 0
Measurement of the pulmonary diffusing capacity for O2 (DO2) by a rebreathing technique in man. 用再呼吸技术测定人肺氧弥散量。
Archivio di fisiologia
Pub Date : 1973-06-30
P Cerrtelli, A Veicsteinas, J Teichmann, H Magnussen, J Piiper
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引用次数: 0
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