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Interventional nephrology in Puerto Rico: a four year experience. 波多黎各介入肾脏病学:四年经验。
Rafael Baez, Jose Betancourt, Hector J Diaz, Javier Monserrate, Tania Ramírez, Martin Gorrochategui, Carlos Rivera Bermudez, Francisco Torre Leon, Jose L Cangianoa

Puerto Rico is one of the most prevalent areas covered by Medicare in need of renal replacement therapy for which interventional procedures are performed. A cumulative analysis of this management is reported in patients during the period between June 2007 and August 2010. Experience accumulated with 3755 surgical patients revealed that 58% had intravascular catheters, 28% had arteriovenous fistulas, 15% had arteriovenous grafts, and 2% without vascular access. Procedures performed in these patients were: catheter introduction in 1990 cases (33%), angioplasty in 751 cases (20%), angiography in 450 cases (12%), thrombectomy in 413 cases (11%) and venous mapping in 151 cases (4%). The success rates of these procedures were evaluated by analysis of the Society of Interventional Radiology (SIR) criteria for Lifeline Vascular Access. Using SIR definition of success rate for at least one session that includes "declots", placement of catheters and angioplasty, our results revealed an average of 98.2% overall success rate greater than the standard value KDOQI/SIR (> 85% ). This study has documented for four years the success rate of Vascular Interventional Nephrology Center at Auxilio Mutuo Hospital. In order to maintain this success rate is necessary to further evaluate its effectiveness and, most importantly, the development of an educational program for vascular access in patients with chronic kidney disease prior to placement in dialysis units.

波多黎各是医疗保险覆盖的最普遍的地区之一,需要进行肾脏替代治疗,并进行介入性手术。在2007年6月至2010年8月期间,对患者进行了这种管理的累积分析。3755例手术患者的经验表明,58%的患者有血管内导管,28%的患者有动静脉瘘,15%的患者有动静脉移植物,2%的患者没有血管通道。这些患者的手术包括:导管引入1990例(33%),血管成形术751例(20%),血管造影术450例(12%),取栓413例(11%)和静脉测绘151例(4%)。这些手术的成功率是通过分析介入放射学会(SIR)生命线血管通路标准来评估的。使用SIR对至少一个疗程的成功率定义,包括“declots”,导管放置和血管成形术,我们的结果显示平均98.2%的总成功率高于标准值KDOQI/SIR(> 85%)。本研究历时4年,记录了奥西利奥·穆托医院血管介入肾脏病中心的成功率。为了保持这一成功率,有必要进一步评估其有效性,最重要的是,在透析单元安置之前,为慢性肾病患者的血管通路制定教育计划。
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引用次数: 0
President's message. 总统的消息。
Wanda G Vélez Andújar
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引用次数: 0
Intravenous ascorbic acid and hydrogen peroxide in the management of patients with chikungunya. 静脉注射抗坏血酸和过氧化氢治疗基孔肯雅热患者。
Victor Marcial-Vega, Gonzalez Idxian Gonzalez-Terron, Thomas Edward Levy

Chikungunya is a viral illness characterized by severe joint pains, which may persist for months to years. There is no effective treatment for this disease. We treated 56 patients with moderate to severe persistent pains with a single infusion of ascorbic acid ranging from 25-50 grams and hydrogen peroxide (3 cc of a 3% solution) from July to October 2014. Patients were asked about their pain using the Verbal Numerical Rating Scale-11 immediately before and after treatment. The mean Pain Score before and after treatment was 8 and 2 respectively (60%) (p < 0.001); and 5 patients (9%) had a Pain Score of 0. The use of intravenous ascorbic acid and hydrogen peroxide resulted in a statistically significant reduction of pain in patients with moderate to severe pain from the Chikungunya virus immediately after treatment.

基孔肯雅热是一种病毒性疾病,其特征是严重的关节疼痛,可能持续数月至数年。这种疾病没有有效的治疗方法。2014年7月至10月,我们通过单次输注抗坏血酸(25-50克)和过氧化氢(3毫升3%溶液)治疗了56例中度至重度持续性疼痛患者。患者在治疗前后立即使用口头数字评定量表-11询问他们的疼痛。治疗前后平均疼痛评分分别为8分和2分(60%)(p < 0.001);5例(9%)疼痛评分为0分。静脉注射抗坏血酸和过氧化氢治疗后,基孔肯雅病毒引起的中度至重度疼痛患者的疼痛有统计学意义的显著减轻。
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引用次数: 0
Rejection, Recurrence, or Something Else? 拒绝,复发,还是其他原因?
Pub Date : 2014-10-01 DOI: 10.14309/00000434-201410002-01304
Felipe Vélez-González, Veroushka Ballester, I. Antúnez, Rafael Pastranal, E. Torres, C. González-Keelan
Since the introduction of liver transplant as treatment for end-stage liver disease,thousands of lives have been saved. To prevent organ rejection, immunosuppressionis given chronically and hence, patients are at increased risk foropportunistic infections related to immunosuppression, especially within thefirst year after the transplant. However, opportunistic infections can occur yearsafter the transplantation. Disseminated nocardiosis is one of these infections,and although the common presentation includes involvement of skin, lungs, andcentral nervous system. We present an uncommon presentation of nocardiosisin which cholestasis and elevated liver enzymes predominate, mimicking organrejection and liver disease recurrence. Infectious etiologies, including opportunisticmicroorganisms, must always be ruled out in patients presenting elevationin liver enzymes and cholestasis after liver transplant as early diagnosis can preventcomplications such as re-transplantation and even death.
自从将肝移植作为终末期肝病的治疗方法以来,已经挽救了成千上万人的生命。为了防止器官排斥,长期给予免疫抑制,因此,患者发生与免疫抑制相关的机会性感染的风险增加,特别是在移植后的第一年。然而,机会性感染可能在移植数年后发生。播散性诺卡菌病是其中一种感染,尽管常见的表现包括累及皮肤、肺和中枢神经系统。我们提出了一个罕见的诺卡菌病的表现,胆汁淤积和肝酶升高为主,模仿器官排斥和肝脏疾病复发。在肝移植后出现肝酶升高和胆汁淤积的患者中,必须始终排除感染性病因,包括机会性微生物,因为早期诊断可以预防并发症,如再次移植甚至死亡。
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引用次数: 0
Chronic eosinophilic leukemia: a rare cause of hypereosinophilic syndrome. 慢性嗜酸性粒细胞白血病:嗜酸性粒细胞增多综合征的罕见病因。
Cristina Ortiz, Madeline Jimenez, Nelson A Matos

Hypereosinophilic syndromes are a wide group of entities. We present a 24-year-old-male with left lower quadrant abdominal pain, elevated eosinophil counts and splenomegaly. Molecular analysis was positive for FIP1LI -PDGFRA gene compatible with chronic eosinophilic leukemia. He was managed with Imatinib producing resolution of the disease.

嗜酸性粒细胞增多综合征是一个广泛的群体。我们报告一名24岁男性,左下腹腹痛,嗜酸性粒细胞升高和脾肿大。分子分析显示FIP1LI -PDGFRA基因与慢性嗜酸性粒细胞白血病相容。患者接受伊马替尼治疗,病情得到缓解。
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引用次数: 0
Smoking tobacco use among operating room personnel. 手术室工作人员的吸烟情况。
Javier Gonzélez-Castro, Jeamarie Pascual, Luisam Tarrats, Carlos González-Aquino

Objective: To evaluate the prevalence of smoking operating room personnel and compare this with that of the general public. Given the first hand exposure of these individuals to patients with smoking related illnesses, we believe they should have a decreased tendency to smoke.

Methods: A survey instrument was given to operating room personnel in order to learn the prevalence of smoking and other tobacco use related data. Prevalence for the general population and other healthcare related populations was investigated using various search engines and compared with our results.

Results: A total of 113 individuals completed the survey, 6% were found to be current smokers and 15% were found to be past smokers. Data from the Center for Disease Control shows that the prevalence of cigarette smoking among United States adults is 19%, which is significantly higher than what we found in our population (<0.01). In Puerto Rico, the prevalence of smoking is 11%, which is also higher than our study population (p=0.05). Among current smokers, 86% have tried to quit at least once (p=0.02), and all claimed to have knowledge of the possible complications associated with smoking.

Conclusions: Smoking tobacco remains the number one cause of preventable death in the United States despite many efforts to educate the general public on the dangers associated with its use. a more visual or hand's on encounter with the effects of smoking may help decrease tobacco burden in the general population.

目的:了解手术室工作人员吸烟情况,并与普通人群进行比较。考虑到这些人与吸烟相关疾病患者的直接接触,我们认为他们吸烟的倾向应该会减少。方法:对手术室工作人员进行问卷调查,了解其吸烟情况及其他相关烟草使用情况。使用各种搜索引擎调查了普通人群和其他医疗保健相关人群的患病率,并与我们的结果进行了比较。结果:共有113人完成了调查,其中6%的人现在是吸烟者,15%的人过去是吸烟者。来自疾病控制中心的数据显示,美国成年人中吸烟的流行率为19%,这比我们在人口中发现的要高得多(结论:吸烟仍然是美国可预防死亡的头号原因,尽管许多人努力教育公众吸烟的危害。更直观或更直观地接触吸烟的影响可能有助于减轻一般人群的烟草负担。
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引用次数: 0
Use and medicalization of marihuana in cancer patients. 大麻在癌症患者中的使用和医学化。
Elsa Pedro, Fránces M Rodríguez

Anecdotal reports and some clinical studies suggest that marihuana (Cannabis sativa) is effective in treating a variety of conditions such as glaucoma, migraine, pain, spasticity of multiple sclerosis, anorexia, insomnia, depression, nausea and vomiting. One of the diseases mostly associated to a beneficial effect from marihuana is cancer. Twenty-one states of the United States including the District of Columbia have approved the use of marihuana for cancer and other medical conditions. In Puerto Rico, public debate on criminal penalty removal and medicalization of marihuana has intensified. It is considered essential for health professionals to have strong scientific evidence on the effectiveness and safety of medications or substances when recommending them for treating illness. This article discusses scientific evidence and information provided by prestigious organizations on the effectiveness and safety of marihuana and its derivatives in cancer patients.

轶事报道和一些临床研究表明,大麻(大麻sativa)对治疗各种疾病有效,如青光眼、偏头痛、疼痛、多发性硬化症痉挛、厌食症、失眠、抑郁、恶心和呕吐。与大麻的有益作用最相关的疾病之一是癌症。包括哥伦比亚特区在内的美国21个州已经批准使用大麻治疗癌症和其他疾病。在波多黎各,关于取消刑事处罚和大麻医疗化的公开辩论已经加强。卫生专业人员在推荐用于治疗疾病的药物或物质时,必须掌握有关其有效性和安全性的有力科学证据。这篇文章讨论了由著名组织提供的关于大麻及其衍生物对癌症患者的有效性和安全性的科学证据和信息。
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引用次数: 0
[Message from the President]. [总统寄语]。
Pub Date : 2014-01-01 DOI: 10.1159/000262577
Wanda G Vélez Andújar
Choosing Azusa Pacific University to further your academic and professional goals means encounters with world-class faculty as interested in deepening your faith and supporting your individual growth as they are in challenging your scholarship and expanding your skills. An APU education means forming connections with peers, whether online or in residence, whose narratives add richness to the classroom and reflect the vibrancy of our seven Southern California-based locations. An APU degree means challenging and relevant coursework that produces transformation—personal and intellectual. Our community of disciples and scholars form the heartbeat of a warm and caring environment.
选择Azusa太平洋大学来推进你的学术和职业目标意味着与世界一流的教师相遇,他们对加深你的信仰和支持你的个人成长感兴趣,因为他们在挑战你的奖学金和扩展你的技能。APU教育意味着与同行建立联系,无论是在线还是居住,他们的叙述增加了课堂的丰富性,反映了我们位于南加州的七个地点的活力。APU学位意味着具有挑战性和相关的课程,可以产生个人和智力上的转变。我们的弟子和学者社区形成了一个温暖和关怀的环境的心跳。
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引用次数: 0
A VERY RARE NEOPLASM IN AN IMMUNOCOMPETENT PATIENT. 在免疫功能正常的患者中是一种非常罕见的肿瘤。
Emmanuel O González-Irizarry, Luis A Figueroa-Jiménez, Javier Ramos Rossy, Rodolfo Estremera, Javier Monserrate, Amy Lee González-Márquez, Luis Negron-García, Mónica Santiago-Casiano, William Cáceres-Perkins

Kaposi's sarcoma is a rare malignancy requiring infection with human Herpes virus for development. We report a case of a 76-year-old immunocompetent male with recurrent leg cellulitis. The cellulitis eventually developed into a non-healing ulcer and a palpable nodule consistent with nodular Kaposi's sarcoma.

卡波西肉瘤是一种罕见的恶性肿瘤,需要感染人类疱疹病毒才能发病。我们报告了一例 76 岁免疫功能正常男性腿部蜂窝织炎反复发作的病例。蜂窝织炎最终发展为无法愈合的溃疡和可触及的结节,与结节性卡波西肉瘤一致。
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引用次数: 0
GRANULOMATOSIS WITH POLYANGIITIS IN PUERTO RICO: CASE REPORTS. 波多黎各肉芽肿病伴多血管炎:病例报告。
Luis Aranguren, Natalio J Izquierdo, Armando Oliver

Wegener's Granulomatosis or Granulomatosis with Polyangiitis (WG/GPA) is one of the antineutrophil cytoplasmic antibody associated vasculitis. Ocular manifestations the first presenting signs in patients with WG/GPA. We report on two patients diagnosed with WG/GPA and discuss their pertinent clinical findings. Our case report reviews the most common clinical manifestations and ophthalmic associations to compare them with the physical findings of two Hispanic patients. Further, to our knowledge this is the first report of ocular findings in patients with WG/GPA in two Puerto Rican patients.

韦格纳肉芽肿病或肉芽肿病伴多血管炎(WG/GPA)是一种抗中性粒细胞细胞质抗体相关性血管炎。眼部表现是WG/GPA患者的首要表现。我们报告了两例诊断为WG/GPA的患者,并讨论了他们的相关临床表现。我们的病例报告回顾了最常见的临床表现和眼科关联,并将其与两名西班牙裔患者的身体检查结果进行比较。此外,据我们所知,这是两名波多黎各患者的WG/GPA患者眼部发现的第一份报告。
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引用次数: 0
期刊
Boletin de la Asociacion Medica de Puerto Rico
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