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Circumventing the Henderson-Hasselbalch equation 绕过了Henderson-Hasselbalch方程
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80061-1
MD Donald R. Kamens, MD Robert L. Wears, MD Cleve Trimble

Prompt blood-gas analysis consisting of pH, PCO2, and PO2 is now almost universally accessible. PCO2 directly conveys the role of the respiratory mechanism in any acid-base disturbance. The metabolic condition, however, is hidden in a relationship between pH and PCO2 that is most faithfully expressed by the cumbersome Henderson-Hasselbalch equation (HHE). Two methods of quickly determining metabolic status from pH and PCO2, without resorting to the HHE, are discussed. The first method is well known and adjusts pH to represent only metabolic state by quantitatively cancelling the influence of hyper- or hypoventilation. The second method, not previously reported, uses measured pH to estimate the ratio HCO3/PCO2, which, when multiplied by PCO2, equals bicarbonate ion concentration.

由pH、co2分压和PO2组成的快速血气分析现在几乎普遍可用。二氧化碳分压直接传达呼吸机制在任何酸碱紊乱中的作用。然而,代谢条件隐藏在pH和二氧化碳分压之间的关系中,这种关系由繁琐的Henderson-Hasselbalch方程(HHE)最忠实地表达。讨论了两种从pH和PCO2中快速测定代谢状态的方法,而无需诉诸HHE。第一种方法是众所周知的,通过定量地消除换气过度或换气不足的影响来调节pH值,仅代表代谢状态。第二种方法,以前没有报道过,使用测量的pH值来估计HCO3−/PCO2的比率,当乘以PCO2时,等于碳酸氢盐离子浓度。
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引用次数: 2
Carbon monoxide poisoning: The injury and its treatment 一氧化碳中毒:伤害及治疗
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80066-0
MD Roy A.M. Myers, PhD Steven E. Linberg, MD R Adams Cowley
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引用次数: 57
National contract groups 国家合同团体
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80073-8
MD Ronald A. Hellstern
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引用次数: 2
225 skateboard injuries in children 225例儿童滑板伤害
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80081-7
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引用次数: 0
Treatment of drug-induced dystonic reactions 药物性张力障碍反应的治疗
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80059-3
MD An-Shih Lee

Thirty-two cases of drug-induced dystonic reaction were treated by the author with diphenhydramine or benztropine mesylate, intramuscularly or intravenously, in a prospective, nonrandomized fashion. Recovery time with the two drugs was compared. Benztropine mesylate lessened recovery time in this case series. An epidemiological study of drug-induced dystonic reactions found that most of the patients were drug abusers. The commonest offensive agent in this case series was haloperidol. The most common dystonic reactions seen were buccolingual and torticollic.

作者以前瞻性、非随机的方式,用苯海拉明或甲磺酸苄托品肌内或静脉注射治疗32例药物性张力障碍反应。比较两种药物的恢复时间。甲磺酸苯托品缩短了本病例系列的恢复时间。一项药物性张力障碍反应的流行病学研究发现,大多数患者是药物滥用者。本病例系列中最常见的进攻性药物是氟哌啶醇。最常见的张力障碍反应是舌部张力障碍和斜颈张力障碍。
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引用次数: 30
What is past is prologue 什么是过去是序幕
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80069-6
MD John P. McDade (President)
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引用次数: 118
UA/EM call for abstracts UA/EM调用摘要
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80067-2
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引用次数: 0
Asystole and its treatment: The possible role of the parasympathetic nervous system in cardiac arrest 心脏骤停及其治疗:副交感神经系统在心脏骤停中的可能作用
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80058-1
MD Daniel C. Brown (Research Fellow) , MD A. James Lewis , MD J. Michael Criley

Parasympathetic tone may be high during ventricular asystole because of reflex vagal stimulation from a number of sources. Eight patients in cardiac arrest were treated with cardiopulmonary resuscitation. All eight patients had ventricular asystole as the initial rhythm or as the result of defibrillation. Six patients failed to respond to 5 cc to 20 cc of 1:10,000 epinephrine intravenously (IV). In all eight cases a regular rhythm (sinus in seven, idioventricular in one) appeared within 30 seconds of administration of the last dose of atropine (1 mg to 2 mg IV). Five patients (62.5%) lived 12 hours, three (37.5%) were discharged from the hospital. These results suggest that atropine may be of value in the treatment of ventricular asystole.

副交感神经张力在心室收缩时可能很高,这是由于多种来源的迷走神经反射性刺激。对8例心脏骤停患者进行心肺复苏治疗。所有8例患者的初始心律或除颤结果均为心室无搏。6例患者静脉注射1:10万肾上腺素5cc至20cc无效。所有8例患者在给药最后一次阿托品(静脉注射1mg至2mg)后30秒内出现规律心律(7例窦性心律,1例室性心律)。5例患者(62.5%)存活12小时,3例(37.5%)出院。这些结果表明,阿托品可能是有价值的治疗心室骤停。
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引用次数: 70
Suicidal overdoses with hypoglycemic agents 过量服用降糖药自杀
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80062-3
MD William F. Bobzien III

Suicide attempts using hypoglycemic agents are uncommon but are associated with a high level of morbidity and mortality. Their recognition is sometimes difficult and the duration of hypoglycemic effect is often prolonged. Two cases that illustrate the difficulties encountered in recognition and therapy are described. Effective therapy depends on adequate glucose supplementation to maintain euglycemia. Therapeutic intervention often must be maintained for several days. Glucocorticoids may be useful in difficult cases. Other modes of therapy, including glucagon, are unproven or controversial.

使用降糖药自杀的企图并不常见,但与高发病率和死亡率相关。它们有时难以识别,降糖作用的持续时间往往延长。描述了两个案例,说明了在识别和治疗中遇到的困难。有效的治疗依赖于充足的葡萄糖补充来维持血糖正常。治疗干预通常必须维持数天。糖皮质激素可能对疑难病例有用。其他治疗模式,包括胰高血糖素,是未经证实或有争议的。
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引用次数: 20
Emergency case recognition of spinal cord injuries 脊髓损伤的急诊病例识别
Pub Date : 1979-11-01 DOI: 10.1016/S0361-1124(79)80072-6
MD Thomas A. Kelley Jr (Medical Director)
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引用次数: 0
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