During the years 1968-1988 270 patients with tumors and mediastinal cysts were treated surgically. In 48 (17.8%) cysts were found (26 males, 22 females, age ranged 10-63 years, mean 40.1 years). In 24 pericardial cysts were found. In 24 the cysts derived from the forgut. 23 subjects (47.9%) were symptomless. In all the cysts were removed. Mortality was not seen. 47 patients are included in long-term observation.
Here is presented a case of woman treated by immunosuppressive preparations because of systemic lupus erythematosus with ski manifestations as tubercles and ulcerations on skin of trunk and extremities. On the basis of histological examination of tubercle skin specimens and mycological examinations of material obtained from skin ulcerations cryptococcosis was diagnosed. Disease was limited to skin that was an entry of infection. Patient was treated by Amphotericin B administered intravenously and Flucitosine per os. Amphotericin B was also applied topically. The results of cultures became gradually negative, up to total disappearance of fungus cells in direct specimens, prepared from examined material. After treatment continuing for 5 months only discoloured scars were observed on sick skin.
The respiratory pattern was evaluated in 32 newborn infants (21--premature infants). In 17 cases the cause of the respiratory insufficiency was the respiratory distress syndrome, in 15 pneumonias. Basing on registered spirograms the mean inspiratory time (Ti), the duration of the respiratory cycle (Ttot), time component (Ti/Ttot), respiratory frequency (f), normalized respiratory volume according to weight (Vt/kg) and Vt/Ti ratio were calculated. The authors did not find any differences in breathing pattern components between premature and at term infants nor between infants with RDS and pneumonias. In infants with RDS a shortened duration of inspiration was seen during the initial four days. Statistically significant differences were found in components of the respiratory pattern between studied and healthy infants.
A case report of lymphangioleiomyomatosis is presented. The authors discussed the clinical picture, radiological and functional changes and the best therapeutical methods in such disorders.
The study was carried out on 290 males with occupational organic dust exposition. In all bronchoprovocation test with Erwinia herbicola antigen were carried out. A positive test was seen in 16.2% of the studied subjects. Bronchial hyperreactivity to Erwinia herbicola allergen depended on living environs, occupational exposure and symptoms characteristic of allergic alveolitis.
The authors present their original experience in epidemiological and clinical diagnosis of allergical respiratory disorders in farm workers in Tschechoslovakia in the years 1966-1985. Bronchial asthma was seen in 21 subjects, allergical rhinitis in 5, allergical alveolitis (Farmer's lung) in 17. Most often with exposure while working with animals were effected. Skin prick tests were most often positive to grass, dust and cat fur allergens. Allergic alveolitis was most often of the subacute and chronic type. In 17 a positive serum aspergillin test was found.
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