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Progress in clinical cancer最新文献

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Coordinated treatment of childhood rhabdomyosarcoma. 儿童横纹肌肉瘤的协同治疗。
Pub Date : 1975-01-01
C B Pratt, H O Hustu, D Pinkel
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引用次数: 0
Current evidence about the causes of malignant melanoma. 关于恶性黑色素瘤病因的现有证据。
Pub Date : 1975-01-01
J A Lee
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引用次数: 0
Immunology of breast cancer: clinical implications. 乳腺癌免疫学:临床意义。
Pub Date : 1975-01-01
M M Black
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引用次数: 0
Cancer in organ transplant recipients. 器官移植受者的癌症
Pub Date : 1975-01-01
I Penn
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引用次数: 0
Trends in cancer patient survival rates. 癌症患者存活率的趋势。
Pub Date : 1975-01-01
S J Cutler, M H Myers, L M Axtell
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引用次数: 0
Integrated therapy for Ewing's sarcoma. 尤因氏肉瘤的综合治疗。
Pub Date : 1975-01-01
R E Johnson, T C Pomeroy
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引用次数: 0
Combined therapy in advanced head and neck cancer: hydroxyurea and radiotherapy. 晚期头颈癌的联合治疗:羟基脲和放疗。
Pub Date : 1975-01-01
D H Hussey, J P Abrams
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引用次数: 0
The search for RNA tumor viruses in human cancer. 在人类癌症中寻找RNA肿瘤病毒。
Pub Date : 1975-01-01
S A Aaronson, J Schlom
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引用次数: 0
Histology and prognosis of cutaneous melanoma. 皮肤黑色素瘤的组织学和预后。
Pub Date : 1975-01-01
J H Little
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引用次数: 0
Risk factors in breast cancer. 乳腺癌的风险因素。
Pub Date : 1975-01-01
A S Ketcham, W F Sindelar

Various factors have been found to be predictors of the relative risk of breast cancer (Table 2). Epidemiologic variables influencing breast cancer risk include age, marital status, geographic location, racial or ethnic extraction, and socioeconomic status. The risk of developing mammary carcinoma is increased with advancing age, among unmarried women, in the United States and Europe, and among women of higher socioeconomic classes. Conversely, a decreased breast cancer risk is observed among fertile married women in Asian countries, among Oriental women, and in lower socioeconomic classes. Reproductive history plays an important role in determining breast cancer risk. The risk of developing mammary carcinoma is increased by an early menarche and decreased by delayed first menses. A late natural menopause increases breast cancer risk while an early oophorectomy offers protection. Hormonal factors are thought to play important roles in the etiology of breast cancer, but the contributions of estrogenic and androgenic influences to mammary neoplasia have not been delineated. Certain estrogen fractions have been implicated as mammary carcinogens, while certain adrenal androgenic steroids have been shown to be promotors of breast cancers. Chronic cystic mastitis is associated with an increased breast cancer risk. A positive family history increases the risk of developing mammary carcinoma and a past history of breast cancer markedly increases the possibility of subsequent breast neoplasia.

已发现有多种因素可预测乳腺癌的相对风险(表 2)。影响乳腺癌风险的流行病学变量包括年龄、婚姻状况、地理位置、种族或民族血统以及社会经济状况。在美国和欧洲,随着年龄的增长,未婚女性以及社会经济地位较高的女性罹患乳腺癌的风险会增加。相反,在亚洲国家,已婚已育妇女、东方妇女和社会经济地位较低的妇女患乳腺癌的风险降低。生育史在决定乳腺癌风险方面起着重要作用。初潮过早会增加罹患乳腺癌的风险,初潮推迟则会降低罹患乳腺癌的风险。自然绝经晚会增加罹患乳腺癌的风险,而早期进行输卵管切除术则可提供保护。荷尔蒙因素被认为在乳腺癌的病因中起着重要作用,但雌激素和雄激素对乳腺肿瘤的影响尚未明确。某些雌激素成分被认为是乳腺癌的致癌物质,而某些肾上腺雄激素类固醇则被证明是乳腺癌的促进因素。慢性囊性乳腺炎与乳腺癌风险增加有关。阳性家族史会增加罹患乳腺癌的风险,而既往的乳腺癌病史则会明显增加以后发生乳腺肿瘤的可能性。
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引用次数: 0
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Progress in clinical cancer
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