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A Preliminary Assessment of the Utility of Large-Caliber Processed Nerve Allografts for the Repair of Upper Extremity Nerve Injuries 大口径异体神经移植物修复上肢神经损伤的初步评价
Pub Date : 2017-01-01 DOI: 10.1177/1558944716646782
J. Isaacs, B. Safa
Background: Cabled sensory nerve autografts are the historical gold standard for overcoming gaps in larger diameter nerves as repair utilizing large-diameter autograft risks central graft necrosis. Commercially available processed nerve allograft (PNA) is available in diameters up to 5 mm but represents an acellular 3-dimensional matrix as opposed to viable tissue. The purpose of this study is to specifically evaluate whether similar concerns regarding the use of large-caliber PNA are warranted. Methods: The RANGER Registry is an active database designed to collect injury, repair, safety, and outcomes data for PNAs (Avance® Nerve Graft; AxoGen, Inc, Alachua, Florida) according to an institutional review board–approved protocol. The database was queried for patients presenting with large-caliber nerve allograft repairs in the upper extremity. Identified patients reporting quantitative outcomes with a minimum of 9-month follow-up were included in the data set. Results: The large-caliber PNA subgroup included 13 patients with 15 injuries. The mean ± SD age was 36 ± 22 years. Large-caliber single-stranded repairs included twelve 4- to 5-mm-diameter grafts. Large-caliber cabled repairs included the combined use of 3- to 4-mm and 4- to 5-mm-diameter nerve allografts in 3 repairs. The mean nerve gap was 33 ± 10 mm with a mean follow-up time of 13 months. Available quantitative data reported meaningful recovery of sensory and motor function in 67% and 85% of the repairs, respectively. Conclusion: Although based on a small subset of patients, PNAs of up to 5 mm in diameter appear capable of supporting successful nerve regeneration.
背景:带电缆的自体感觉神经移植物是克服大直径神经间隙的历史黄金标准,因为使用大直径自体移植物进行修复有导致中枢移植物坏死的风险。市售的经处理的同种异体神经(PNA)的直径可达5mm,但与活组织相比,它代表了一种无细胞的三维基质。本研究的目的是具体评估是否有必要对大口径PNA的使用提出类似的担忧。方法:RANGER注册表是一个活跃的数据库,旨在根据机构审查委员会批准的方案收集PNA(Avance®神经移植;AxoGen,Inc,Alachua,Florida)的损伤、修复、安全性和结果数据。数据库中查询了上肢大口径同种异体神经修复的患者。已确定的患者报告了至少9个月随访的定量结果,这些患者被纳入数据集中。结果:大口径PNA亚组包括13例患者和15例损伤。平均±SD年龄为36±22岁。大口径单链修复包括12个直径4至5毫米的移植物。大口径有线修复包括在3次修复中联合使用直径为3至4毫米和4至5毫米的同种异体神经移植物。平均神经间隙为33±10mm,平均随访时间为13个月。现有的定量数据显示,67%和85%的修复中感觉和运动功能得到了有意义的恢复。结论:尽管基于一小部分患者,直径高达5毫米的PNA似乎能够支持成功的神经再生。
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引用次数: 35
Comments on the article “Non-Surgical Treatment of Lateral Epicondylitis: A Systematic Review of Randomized Controlled Trials” 《非手术治疗外上髁炎:随机对照试验的系统回顾》一文评论
Pub Date : 2017-01-01 DOI: 10.1177/1558944716643280
D. Stasinopoulos
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引用次数: 1
Gouty Tenosynovitis of the Distal Biceps Tendon Insertion Complicated by Partial Rupture 痛风性二头肌远端肌腱止点腱鞘炎并发部分断裂
Pub Date : 2017-01-01 DOI: 10.1177/1558944715627639
Ricky Fairhurst, A. Schwartz, L. M. Rozmaryn
Background: Given the appreciable prevalence of gout, gout-induced tendon ruptures in the upper extremity are extremely rare. Although these events have been reported only 5 times in the literature, all in patients with a risk factor for or history of gout, they have conspicuously never been diagnosed in the shoulder or elbow. Methods: A 45-year-old, right-hand-dominant man with a history of gout presented with pain in his right anterior elbow and weakness in his forearm after a trivial injury. Results: Here, we report the first case of gouty tenosynovitis of the distal biceps tendon insertion complicated by partial rupture, a composite diagnosis supported by both intraoperative and histological observations. Conclusions: In patients who are clinically diagnosed with biceps tendon rupture and have a history of gout, it is important to consider the possibility of a gout-related pathological manifestation causing or simulating tendon rupture.
背景:鉴于痛风的普遍存在,痛风引起的上肢肌腱断裂是非常罕见的。虽然这些事件在文献中只报道了5次,所有患者都有痛风的危险因素或病史,但它们从未在肩部或肘部被诊断出来。方法:一名45岁,以右手为主的男性,有痛风病史,在轻微损伤后出现右前肘疼痛和前臂无力。结果:在这里,我们报告了第一例痛风性肱二头肌腱远端止点腱鞘炎并发部分断裂,这是一种由术中和组织学观察支持的综合诊断。结论:临床上诊断为肱二头肌肌腱断裂且有痛风病史的患者,应考虑是否有痛风相关病理表现导致或模拟肌腱断裂。
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引用次数: 8
Long-Term Outcomes of Scaphoid Malunion Scaphoid畸形愈合的长期结果
Pub Date : 2017-01-01 DOI: 10.1177/1558944716643295
B. Gillette, P. Amadio, S. Kakar
Background: The optimal treatment of patients with a scaphoid malunion remains controversial. The long-term outcomes of operative and nonoperative management have not been established. Methods: We conducted a retrospective review of the outcomes of all scaphoid malunions treated at single institution over a 30-year period. This included patients who underwent corrective osteotomy, salvage procedures (ie, dorsal cheilectomy, radial styloidectomy, and scaphoidectomy with midcarpal fusion), and those who refused operative intervention. The Mayo Wrist Score was determined at the time of surgical evaluation. Patient-Rated Wrist Evaluation (PRWE) and Disabilities of the Arm, Shoulder and Hand (QuickDASH) surveys were sent to all patients for long-term follow-up. Results: Seventeen patients had follow-up at a mean 21.4 years (range, 12-30 years). The mean initial lateral intrascaphoid angle was 58°. Of the 17 patients, 11 proceeded with surgery and 6 opted for nonoperative management. A corrective osteotomy was performed in 4 patients. Of the remaining 7 surgical patients, 5 patients underwent procedures such as cheilectomy and radial styloidectomy, whereas 2 patients had a scaphoidectomy with midcarpal fusion. The final mean PRWE and QuickDASH scores for corrective osteotomy, salvage procedures, and nonoperative treatment were 23 and 6, 18 and 10, and 33 and 22, respectively. Conclusion: Long-term outcomes were similar between operative and nonoperative management.
背景:舟状骨畸形愈合患者的最佳治疗方法仍存在争议。手术和非手术治疗的长期结果尚未确定。方法:我们对30年来在单一机构治疗的所有舟状骨畸形愈合的结果进行了回顾性回顾。这包括接受矫正截骨术、保留手术(即背侧颧骨切除术、桡骨茎突切除术和腕中部融合的舟状骨切除术)和拒绝手术干预的患者。Mayo手腕评分在手术评估时确定。对所有患者进行患者腕部评分评估(PRWE)和手臂、肩部和手部残疾(QuickDASH)调查,进行长期随访。结果:17例患者平均随访21.4年(范围12-30年)。平均初始外侧肩胛内角为58°。17例患者中,11例接受手术治疗,6例选择非手术治疗。4例患者行矫正截骨术。在其余7例手术患者中,5例患者接受了诸如颧骨切除术和桡骨茎突切除术等手术,而2例患者接受了舟状骨切除术并腕中部融合。矫正截骨、抢救手术和非手术治疗的最终平均PRWE和QuickDASH评分分别为23和6分、18和10分、33和22分。结论:手术治疗与非手术治疗远期疗效相近。
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引用次数: 20
Biceps to Triceps Transfer in Tetraplegic Patients 四肢瘫痪患者二头肌到三头肌的转移
Pub Date : 2017-01-01 DOI: 10.1177/1558944716646764
J. Medina, A. Marcos-García, I. Jiménez, G. Muratore, J. L. Méndez-Suárez
Background: Management and indications for surgery in the tetraplegic patient are highly complex because of the substantial functional deficits that they present and their effect on their daily activity. Our purpose was to evaluate the functional outcome in tetraplegic patients who underwent biceps-to-triceps transfer surgery according to Zancolli’s modified technique. Methods: This is a retrospective study of 6 biceps-to-triceps transfers using Zancolli’s modified technique in 4 patients. Mean follow-up was 45 months. We evaluated each patient’s DASH (Disabilities of the Arm, Shoulder and Hand) score before surgery and 12 months later. Results: In the 6 arms that underwent surgery, full and active elbow extension against gravity at 12 months after surgery was achieved. The mean DASH score was 73.2 preoperatively and 20.8 twelve months postoperatively. One complication occurred. One patient reported loss of elbow flexion preventing thigh lift for transfers. This was resolved with a program of rehabilitation and specific muscle strengthening Conclusions: Zancolli’s modified technique is simple and effective, with few complications, whereby we can provide more autonomy for the tetraplegic patient.
背景:四肢瘫痪患者的手术管理和适应症非常复杂,因为它们存在严重的功能缺陷及其对日常活动的影响。我们的目的是评估根据Zancoli改良技术进行二头肌至三头肌转移手术的四肢瘫痪患者的功能结果。方法:对4例患者采用Zancoli改良技术将6头二头肌转移至三头肌进行回顾性研究。平均随访时间为45个月。我们在手术前和12个月后评估了每位患者的DASH(手臂、肩膀和手部残疾)评分。结果:在接受手术的6只手臂中,在手术后12个月,实现了充分和积极的肘部抗重力伸展。平均DASH评分术前为73.2,术后12个月为20.8。出现一个并发症。一名患者报告称,肘部屈曲功能丧失,无法进行大腿抬高转移。通过康复和特定的肌肉强化计划解决了这一问题。结论:Zancoli改良的技术简单有效,并发症少,因此我们可以为四肢瘫痪患者提供更多的自主权。
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引用次数: 12
Hand Surgery and Fluoroscopic Eye Radiation Dosage 手外科和透视眼辐射剂量
Pub Date : 2017-01-01 DOI: 10.1177/1558944716643279
Mark L. Wang, C. E. Hoffler, Asif M. Ilyas, William H. Kirkpatrick, P. Beredjiklian, C. Leinberry
Background: The purpose of this study is to (1) perform a prospective pilot comparison of the impact of large versus mini C-arm fluoroscopy on resultant eye radiation exposure and (2) test the hypothesis that the use of either modality during routine hand surgery does not exceed the current recommended limits to critical eye radiation dosage. Methods: Over a 12-month period, eye radiation exposure was prospectively measured by a board-certified hand surgeon using both large and mini C-arm fluoroscopy. For each modality, accumulated eye radiation dosage was measured monthly, while fluoroscopic radiation output was recorded, including total exposure time and dose rate. Results: A total of 58 cases were recorded using large C-arm and 25 cases using mini C-arm. Between the 2 groups, there was not a significant difference with total exposure time (P = .88) and average dose rate per case (P = .10). With the use of either modality, average monthly eye radiation exposure fell within the undetectable range (<30 mrem), significantly less than the current recommended limit of critical eye radiation (167 mrem/month). Conclusions: The impact of various fluoroscopic sources on eye radiation exposure remains relatively unexplored. In this study, the minimal detectable eye radiation dosages observed in both groups were reliably consistent. Our findings suggest that accumulated eye radiation dosage, from the use of either fluoroscopic modality, does not approach previously reported levels of critical radiation loads.
背景:本研究的目的是(1)对大型和小型C型臂荧光镜检查对眼睛辐射暴露的影响进行前瞻性试点比较,以及(2)验证在常规手部手术中使用任何一种方式都不会超过当前推荐的关键眼睛辐射剂量限值的假设。方法:在12个月的时间里,由委员会认证的手外科医生使用大型和小型C型臂荧光镜对眼睛辐射暴露进行前瞻性测量。对于每种模式,每月测量累积的眼部辐射剂量,同时记录荧光透视辐射输出,包括总暴露时间和剂量率。结果:大C型臂58例,小C型臂25例。两组之间的总暴露时间(P=.88)和每个病例的平均剂量率(P=.10)没有显著差异。使用任何一种模式,平均每月眼部辐射暴露量都在检测不到的范围内(<30 mrem),显著低于目前建议的关键眼部辐射限值(167 mrem/月)。结论:各种荧光镜光源对眼睛辐射暴露的影响仍然相对未被探索。在这项研究中,在两组中观察到的最小可检测眼睛辐射剂量是可靠一致的。我们的研究结果表明,无论使用哪种荧光镜检查方式,累积的眼部辐射剂量都不会达到之前报道的临界辐射负荷水平。
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引用次数: 6
The Lateral Proximal Phalanx Flap for Contractures and Soft Tissue Defects in the Proximal Interphalangeal Joint Phalanx外侧近端皮瓣治疗近端咽间关节挛缩和软组织缺损
Pub Date : 2017-01-01 DOI: 10.1177/1558944716646781
A. Beltrán, C. Romero
Background: The management of contractures and soft tissue defects in the proximal interphalangeal (PIP) finger joint remains a challenge. We report a transposition flap from the lateral skin of the proximal phalanx that is based on perforating branches of the digital arteries and can be used safely for both palmar and dorsal cover defects. Methods: We first completed an anatomic study, dissecting 20 fingers in fresh cadavers with arterial injections and made the new flap in patients with dorsal or palmar defects in PIP joints. Results: In cadavers, we can reveal 4 constant branches from each digital artery in the proximal phalanx, with the more distal just in the PIP joint constituting the flap pedicle. Between February 2010 and February 2015, we designed 33 flaps in 29 patients, 7 for dorsal and 26 for palmar defects, with no instances of flap necrosis and 4 distal epidermolysis. The patients were between 4 and 69 years with no major complications, and all of the skin defects in the PIP joint were resolved satisfactorily without any relevant sequelae at the donor site. Conclusions: This flap procedure is an easy, reliable, versatile, and safe technique, and could be an important tool for the management of difficult skin defects and contractures at the PIP joint level.
背景:手指近端指间关节(PIP)挛缩和软组织缺损的治疗仍然是一个挑战。我们报道了一种基于指动脉穿孔分支的近节指骨外侧皮肤转位皮瓣,可安全用于掌侧和背侧覆盖层缺损。方法:我们首先完成了一项解剖学研究,在新鲜尸体上用动脉注射解剖了20根手指,并为PIP关节背侧或手掌侧缺损的患者制作了新的皮瓣。结果:在尸体上,我们可以从指骨近端的每个指动脉中发现4个恒定的分支,其中更远端的仅在PIP关节中构成皮瓣蒂。在2010年2月至2015年2月期间,我们为29名患者设计了33个皮瓣,其中7个用于背侧缺损,26个用于掌侧缺损,没有皮瓣坏死和4个远端表皮松解。患者年龄在4至69岁之间,没有重大并发症,PIP关节的所有皮肤缺陷都得到了满意的解决,在供体部位没有任何相关后遗症。结论:该皮瓣手术是一种简单、可靠、通用和安全的技术,可作为治疗PIP关节层面疑难皮肤缺损和挛缩的重要工具。
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引用次数: 6
A Survey of the Use of Ultrasound by Upper Extremity Surgeons 上肢外科医生超声应用的调查
Pub Date : 2017-01-01 DOI: 10.1177/1558944716646779
William L. Wang, K. Kruse, J. Fowler
Background: Ultrasound is a versatile imaging modality that can be used by upper extremity surgeons for diagnostic purposes and guided injections. The perceptions of ultrasound for diagnosis and treatment among upper extremity surgeons and its barriers for adoption have not been formally surveyed. The purpose of this study is to determine the current usage of musculoskeletal ultrasound for diagnostic purposes and guided injections by upper extremity surgeons and their reasons for using it or not using it in practice. Methods: A 22-question survey was distributed to the American Society for Surgery of the Hand (ASSH). The survey questions consisted of respondent characteristic questions and questions pertaining to the use of ultrasound. Chi-square analysis was performed to assess for a difference in ultrasound usage across respondent characteristics. Results: Three hundred four (43%) answered that they have an ultrasound machine in their office; Fifty-one percent (362) of the respondents use ultrasound for diagnostic purposes. Fifty-five (8%) of the survey respondents use ultrasound to diagnose carpal tunnel syndrome; 168 (23.5%) respondents reported that they use ultrasound for guided injections. There was a statistically significant difference between access to an ultrasound machine in the office by practice setting and use of ultrasound for diagnostic purposes by practice setting. Conclusions: The use of ultrasound by upper extremity surgeons is split for diagnostic purposes, with fewer surgeons using ultrasound to diagnose carpal tunnel syndrome and guided injections. Ultrasound machine availability and the use of ultrasound for diagnosis appear to be influenced by practice setting.
背景:超声是一种通用的成像方式,上肢外科医生可以使用它进行诊断和引导注射。上肢外科医生对超声诊断和治疗的看法及其采用的障碍尚未得到正式调查。本研究的目的是确定上肢外科医生目前使用肌肉骨骼超声进行诊断和引导注射的情况,以及他们在实践中使用或不使用的原因。方法:向美国手外科学会(ASSH)分发一份22个问题的调查。调查问题包括受访者的特征问题和与超声波使用有关的问题。卡方分析用于评估受访者特征之间超声使用的差异。结果:304人(43%)回答说他们的办公室里有超声波机;51%(362)的受访者使用超声波进行诊断。五十五(8%)的受访者使用超声波诊断腕管综合征;168名(23.5%)受访者报告称,他们使用超声波进行引导注射。按实践设置在办公室使用超声波机与按实践设置使用超声波进行诊断之间存在统计学上的显著差异。结论:上肢外科医生使用超声波进行诊断是分开的,使用超声波诊断腕管综合征和引导注射的外科医生较少。超声机的可用性和超声诊断的使用似乎受到实践环境的影响。
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引用次数: 11
Prospective Evaluation of Opioid Consumption Following Carpal Tunnel Release Surgery. 腕管释放手术后阿片类药物消费的前瞻性评价
Pub Date : 2017-01-01 Epub Date: 2016-04-29 DOI: 10.1177/1558944716646765
Talia Chapman, Nayoung Kim, Mitchell Maltenfort, Asif M Ilyas

Background: Postoperative pain management and opioid consumption following carpal tunnel release (CTR) surgery may be influenced by many variables. To understand factors affecting opioid consumption, a prospective study was undertaken with the hypothesis that CTR performed under local anesthesia (wide awake local anesthesia with no tourniquet [WALANT]) would result in increased opioid consumption postoperatively compared with cases performed under sedation. Methods: All patients undergoing open CTR surgery were consecutively enrolled over a 6-month period. Information collected included patient demographics, surgical technique, amount and type of narcotic prescribed, number of pills taken, and type of anesthesia. Results: 277 patients were enrolled (56% women, 44% men). On average, 21 pills were prescribed, and 4.3 pills (median = 2) were consumed. There was no difference in consumption between patients who received WALANT (78 cases) versus (198 cases) sedation (4.9 vs 3.9 pills, respectively) (P = .22). There was no difference in opioid consumption based on insurance type (P = .47) or type of narcotic (P = .85). However, more men consumed no opioids (47%) compared with women (36%) (P < .05) and older patients consumed less than younger patients (P < .05). Conclusions: Opioid consumption following CTR is more influenced by age and gender, and less influenced by anesthesia type, insurance type, or the type of opioid prescribed. Many more opioids were prescribed than needed, on an average of 5:1. Many patients, particularly older patients, do not require any opioid analgesia after CTR.

背景:腕管释放(CTR)手术后疼痛管理和阿片类药物的使用可能受到许多变量的影响。为了了解影响阿片类药物消耗的因素,我们进行了一项前瞻性研究,假设在局麻下(无止血带的全清醒局麻[WALANT])进行CTR会导致术后阿片类药物消耗比镇静下增加。方法:所有接受开放式CTR手术的患者在6个月的时间内连续入组。收集的信息包括患者的人口统计资料、手术技术、处方麻醉药的数量和类型、服用的药片数量和麻醉的类型。结果:277例患者入组(56%女性,44%男性)。平均处方21片,服用4.3片(中位数= 2)。服用WALANT(78例)和镇静(198例)(分别为4.9片和3.9片)的患者之间的消耗量没有差异(P = 0.22)。保险类型(P = 0.47)和麻醉药品类型(P = 0.85)在阿片类药物消费方面没有差异。然而,男性不服用阿片类药物(47%)多于女性(36%)(P < 0.05),老年患者服用阿片类药物少于年轻患者(P < 0.05)。结论:CTR后阿片类药物消费受年龄和性别的影响较大,受麻醉类型、保险类型和处方阿片类药物类型的影响较小。开出的阿片类药物比需要的多得多,平均为5:1。许多患者,特别是老年患者,在CTR后不需要任何阿片类镇痛药。
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引用次数: 85
Brachial Plexus Blockade Causes Subclinical Neuropathy 臂丛阻滞引起亚临床神经病变
Pub Date : 2017-01-01 DOI: 10.1177/1558944716650411
Donato J Perretta, Matthew J. Gotlin, K. Brock, N. Paksima, M. Gottschalk, G. Cuff, M. Rettig, A. Atchabahian
Background: The objective of this study is to determine subclinical changes in hand sensation after brachial plexus blocks used for hand surgery procedures. We used Semmes-Weinstein monofilament testing to detect these changes. We hypothesized that patients undergoing brachial plexus nerve blocks would have postoperative subclinical neuropathy detected by monofilament testing when compared with controls. Methods: In total, 115 hand surgery adult patients were prospectively enrolled in this study. All patients undergoing nerve-related procedures were excluded as well as any patients with preoperative clinically apparent nerve deficits. Eighty-four patients underwent brachial plexus blockade preoperatively, and 31 patients underwent general anesthesia (GA). Semmes-Weinstein monofilament testing of the hand was performed preoperatively on both the operative and nonoperative extremities and postoperatively at a mean of 11 days on both hands. Preoperative and postoperative monofilament testing scores were compared between the block hand and the nonoperated hand of the same patient, as well as between the block hands and the GA-operated hands. Results: There were no recorded clinically relevant neurologic complications in the block group or GA group. A statistically significant decrease in sensation in postoperative testing in the operated block hand compared with the nonoperated hand was noted. When comparing the operated block hand with the operated GA hand, there was a decrease in postoperative sensation in the operated block hand that did not reach statistical significance. Conclusions: Brachial plexus blockade causes subtle subclinical decreases in sensibility at short-term follow-up, without any clinically relevant manifestations.
背景:本研究的目的是确定用于手外科手术的臂丛阻滞术后手部感觉的亚临床变化。我们使用Semmes-Weinstein单丝测试来检测这些变化。我们假设,与对照组相比,接受臂丛神经阻滞的患者术后通过单丝试验检测出亚临床神经病变。方法:共纳入115例成年手外科患者。所有接受神经相关手术的患者以及术前临床明显神经缺损的患者均被排除在外。术前行臂丛神经阻滞84例,全麻31例。在手术前和非手术端进行Semmes-Weinstein单丝测试,术后双手平均11天进行测试。比较同一患者阻滞手与未手术手、阻滞手与ga手术手术前、术后单丝测试得分。结果:阻滞组和GA组均无临床相关神经系统并发症记录。在术后测试中,与未手术的手相比,手术手的感觉有统计学意义的下降。手术块手与GA手比较,手术块手术后感觉下降,但差异无统计学意义。结论:臂丛神经阻滞在短期随访中引起敏感性的细微亚临床下降,无临床相关表现。
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引用次数: 3
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The Hand
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