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Congenital heart block 先天性心脏传导阻滞
Pub Date : 2020-02-10 DOI: 10.32388/8bhqgl
Neonatal lupus (NL) is a syndrome diagnosed in neonatal infants, whose mothers frequently suffer from autoimmune rheumatic diseases, manifested by two major signs: skin lesion and cardiac lesion. The paper gives data from the history of a description of the syndrome, as well as current ideas on its pathogenesis, considers both typical and rarer clinical manifestations of the disease, and presents approaches to NL therapy and prevention.
新生儿狼疮(Neonatal lupus, NL)是一种常见于新生儿的综合征,其母亲常患自身免疫性风湿性疾病,主要表现为皮肤病变和心脏病变两大体征。本文给出了该综合征的历史描述数据,以及目前对其发病机制的看法,考虑了该疾病的典型和罕见的临床表现,并提出了NL的治疗和预防方法。
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引用次数: 0
Neonatal Thyrotoxicosis 新生儿甲状腺功能亢进
Pub Date : 2020-02-02 DOI: 10.32388/2eczxm
A hypermetabolic syndrome characterized by tachycardia, palpitations, tremor, weight loss, and moist skin that is caused by the elevation of thyroid hormone levels in the serum of the newborn infant or thyroid-axis receptor activation, most commonly due to transplacental passage of thyroid stimulating globulins.
一种以心动过速、心悸、震颤、体重减轻和皮肤湿润为特征的高代谢综合征,由新生儿血清中甲状腺激素水平升高或甲状腺轴受体激活引起,最常见的原因是促甲状腺球蛋白经胎盘转运。
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引用次数: 0
Echocardiography in infants and children. 婴儿和儿童的超声心动图。
Pub Date : 2016-04-30 DOI: 10.1542/9781610020190-part05-echocardiography
C. S. Ping, J. Tay, W. Heng
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引用次数: 3
Double-outlet right ventricle. 右心室双出口。
Pub Date : 2010-01-01 DOI: 10.1007/978-3-540-69837-1_41
S. Sridharan, Gemma Price, O. Tann, M. Hughes, V. Muthurangu, A. Taylor
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引用次数: 0
Congenital heart block 先天性心脏传导阻滞
Pub Date : 2004-01-01 DOI: 10.1007/3-540-29662-X_750
L. Moreland
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引用次数: 0
Etretinate treatment for Harlequin baby. 异丙酸治疗小丑宝宝。
Y C Giam

This report of a Harlequin foetus surviving is due essentially to two factors. a) the intensive care provided to the erythrodermic infant, looking after its nutrition, temperature control and controls of infection and b) the use of a new synthetic Vitamin A acid--Etretinate in the management of dyskeratinisation syndromes. As this is of autosomal recessive inheritance, besides genetic counselling, Singapore has to develop its prenatal diagnostic techniques viz-amniocentesis and ultrasound studies of the skin, to detect dermatological problems.

这一报告的小丑胎儿存活主要是由于两个因素。a)为红皮病婴儿提供重症监护,照顾其营养,温度控制和感染控制;b)在角化不良综合征的管理中使用一种新的合成维生素a酸——依维甲酸。由于这是常染色体隐性遗传,除了遗传咨询外,新加坡还必须发展其产前诊断技术,即羊膜穿刺术和皮肤超声研究,以发现皮肤问题。
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引用次数: 0
The pressure-dependent nature of the rash in Henoch Schönlein purpura. 压力依赖性皮疹在Henoch Schönlein紫癜。
W L Robson, A K Leung, M Lemay

A 10 month old girl with Henoch-Schönlein purpura (HSP) developed a rash predominantly on the anterior aspect of the knees. The authors speculate that this distribution of the rash was due to the pressure effects consequent to crawling and propose that the distribution of the rash in HSP should be described as pressure-dependent rather than merely gravity-dependent. The therapeutic implications of pressure-dependency in HSP are discussed.

一个10个月大的女孩Henoch-Schönlein紫癜(HSP)发展皮疹主要在膝盖的前部。作者推测,这种皮疹的分布是由于爬行造成的压力影响,并提出HSP中皮疹的分布应该被描述为压力依赖,而不仅仅是重力依赖。讨论了压力依赖性对热休克的治疗意义。
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引用次数: 0
Obesity-cerebral-ocular syndrome--a case report. 肥胖-脑-眼综合征1例报告
T H Tay, C M Seet

The obesity-Cerebral-Ocular Syndrome is an uncommon disorder which closely resembles the Laurence-Moon-Biedl-Syndrome. It is also one of several disorders in which obesity, mental retardation and ocular abnormalities are associated. The article presents a case study followed up over 18 years and emphasises the importance of ophthalmic review in preserving visual function.

肥胖-脑-眼综合征是一种罕见的疾病,与劳伦斯-孟-拜德尔综合征非常相似。它也是与肥胖、智力低下和眼部异常相关的几种疾病之一。本文介绍了一个随访超过18年的病例研究,并强调眼科复查对保持视力功能的重要性。
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引用次数: 0
Otoacoustic emissions (OAE) in paediatric hearing screening--the Singapore experience. 耳声发射(OAE)在儿科听力筛查中的应用——新加坡经验。
J Ng, H L Yun

Early identification and rehabilitation of hearing impairment is important for development of language in affected children. Behavioural audiological tests in children are unreliable. Brainstem auditory evoked response (BAER) although a reliable objective test, is difficult to perform. Otoacoustic emissions (OAE) is now thought to be a more practicable screening modality. A study to compare the use of OAE and BAER in the paediatric population was thus undertaken. 100 children underwent OAE and BAER screening in SGH from August 1991 to February 1992. OAE was equally effective when compared with the BAER in testing for passed or failed subjects (p < 0.05, X2 = 4.9). The sensitivity and specificity of OAE with respect to BAER was 95% and 93% respectively. Mean test time was 3.1 minutes for OAE and 28.6 minutes for BAER. Success rate for OAE was 100%. We therefore conclude that OAE is a feasible alternative to the BAER as a hearing screening modality.

听力障碍的早期识别和康复对听力障碍儿童的语言发育非常重要。儿童行为听力学测试是不可靠的。脑干听觉诱发反应(BAER)虽然是一种可靠的客观测试,但很难进行。耳声发射(OAE)现在被认为是一种更可行的筛选方式。因此,进行了一项比较儿科人群使用OAE和BAER的研究。1991年8月至1992年2月,100名儿童在SGH接受了OAE和BAER筛查。与BAER相比,OAE在通过或不通过的测试中同样有效(p < 0.05, X2 = 4.9)。OAE对BAER的敏感性为95%,特异性为93%。OAE组平均检测时间为3.1分钟,BAER组平均检测时间为28.6分钟。OAE成功率为100%。因此,我们得出结论,OAE是一种可行的替代BAER的听力筛查方式。
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引用次数: 0
PaO2, SaO2 and what constitutes adequate oxygenation in the premature newborn. PaO2, SaO2以及什么构成了早产儿的充足氧合。
S P Ng, F Chia

3 neonates admitted into our intensive care unit had their arterial blood gases analyzed. A total of 64, 67 and 73 arterial blood samples were analyzed for the 3 neonates respectively. The relationship between PaO2 and the corresponding SaO2 were plotted in an oxygen hemoglobin dissociation curve. PaO2 of 50mmHg corresponded to SaO2 of 80%, 84% and 92% for the 3 babies respectively, reflecting the fact that SaO2 can differ considerably. PaO2 of 50mmHg or SaO2 of 87% by themselves are inadequate as indicators of lower limit of arterial oxygenation. Indeed a consideration of other factors such as oxygen consumption, cardiac output, hemoglobin concentration are integral to this issue. PaO2 of 70mmHg corresponded to SaO2 of 92%, 93% and 97% respectively. However, at the upper limit of arterial oxygenation, the oxygen hemoglobin dissociation curve flattens out and PaO2 is a more sensitive indicator of the upper limit of arterial oxygenation as compared to SaO2.

我们对入住重症监护室的3名新生儿进行了动脉血气分析。对3例新生儿分别进行了64份、67份和73份动脉血分析。PaO2与相应的SaO2之间的关系绘制在氧血红蛋白解离曲线上。三个婴儿的PaO2为50mmHg对应的SaO2分别为80%,84%和92%,这反映了SaO2可以有很大的差异。PaO2 50mmHg或SaO2 87%本身不足以作为动脉氧合下限的指标。事实上,考虑到其他因素,如耗氧量,心输出量,血红蛋白浓度是这个问题不可或缺的。70mmHg PaO2对应的SaO2分别为92%、93%和97%。而在动脉氧合上限处,氧血红蛋白解离曲线趋于平缓,PaO2是动脉氧合上限较SaO2更为敏感的指标。
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引用次数: 0
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The Journal of the Singapore Paediatric Society
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