{"title":"[9th Scandinavian Congress on Perinatal Medicine. Uppsala, 31 August-2 September 1983. Abstracts].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"37 ","pages":"1-87"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17639363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypoxia; metabolism and regulatory mechanisms in different organs and different clinical conditions. Advanced training course, Uppsala, March 8-12, 1982. Abstracts.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"38 ","pages":"1-124"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17643749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[150 years of the Upsala Medical Society].","authors":"G von Bahr","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"35 ","pages":"1-33"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17806856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reference list of biomedical and clinical publications, Uppsala 1982.","authors":"R Berfenstam, G Dahlström","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"40 ","pages":"5-105"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17818106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomedical and clinical publications: Uppsala 1981.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"36 ","pages":"1-95"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17815854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Need for research laboratories in university hospitals.","authors":"P O Petersson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"40 ","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18014260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypotensive drugs: peripheral versus central effects.","authors":"E Zaimis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"31 ","pages":"52-4"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17985423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Attacks of migraine resulting from climatic cold or heat-stress are a common occurrence in 20-30 per cent of a population exposed to weather changes. The electrical charges (positive ionisation and sferics) engendered by every incoming weather front produce a release of serotonin. In addition there also exists a syndrome of adrenaline deficiency, which may produce headache, while a third reaction, intermittent hyperthyreosis, plays a lesser role in evoking headache. The differential diagnosis of the various types of headache is based upon the profile of neurohormones excreted in the 24-hours urinary output, which permits a comparison between normal and weather-stress days. Such a procedure may provide an appraisal of the underlying metabolic disturbance. Consequently, appropriate treatment can be administered to the patient, and its effect controlled by analysis of any possible neurohormonal change.
{"title":"Migraine and headache due to weather and allied causes and its specific treatment.","authors":"F G Sulman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Attacks of migraine resulting from climatic cold or heat-stress are a common occurrence in 20-30 per cent of a population exposed to weather changes. The electrical charges (positive ionisation and sferics) engendered by every incoming weather front produce a release of serotonin. In addition there also exists a syndrome of adrenaline deficiency, which may produce headache, while a third reaction, intermittent hyperthyreosis, plays a lesser role in evoking headache. The differential diagnosis of the various types of headache is based upon the profile of neurohormones excreted in the 24-hours urinary output, which permits a comparison between normal and weather-stress days. Such a procedure may provide an appraisal of the underlying metabolic disturbance. Consequently, appropriate treatment can be administered to the patient, and its effect controlled by analysis of any possible neurohormonal change.</p>","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"31 ","pages":"41-4"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Tomson, G Tybring, L Bertilsson, K Ekbom, A Rane
Seven patients (mean age 60 years) with idiopathic trigeminal neuralgia previously treated with Carbamazepine(CBZ) were studied as in patients. One patient was examined twice. CBZ (Tegretol) was given twice daily in three different dose-levels to each patient, six days on each level. A single-blind technique was used. The doses were individually chosen with previous dose requirements as a basis. Plasma samples were taken immediately before the morning dose the three last days on each dose-level. CBZ and CBZ-10, 11-epoxide were analysed using liquid chromatography. All pain paroxysms were graded and registered by the patient and pain scores were calculated. The CBZ-doses given ranged from 200 to 1 400 mg/day, the mean being 733 mg/day. In six courses of treatment, patients experienced complete or almost complete pain relief, achieved at CBZ-plasma-concentrations of 24-43 mumol/l. Patients with high pain-scores at plasma-concentrations of 30 mumol/l did not benefit from further dose increase. Small adjustments of plasma-concentration otherwise resulted in pronounced changes in pain-score. Side-effects were not reported below 34 mumol/l. No conclusions could be drawn as to the possible clinical effect of CBZ-10,11-epoxide.
{"title":"Carbamazepine in trigeminal neuralgia: clinical effects in relation to plasma-concentration.","authors":"T Tomson, G Tybring, L Bertilsson, K Ekbom, A Rane","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Seven patients (mean age 60 years) with idiopathic trigeminal neuralgia previously treated with Carbamazepine(CBZ) were studied as in patients. One patient was examined twice. CBZ (Tegretol) was given twice daily in three different dose-levels to each patient, six days on each level. A single-blind technique was used. The doses were individually chosen with previous dose requirements as a basis. Plasma samples were taken immediately before the morning dose the three last days on each dose-level. CBZ and CBZ-10, 11-epoxide were analysed using liquid chromatography. All pain paroxysms were graded and registered by the patient and pain scores were calculated. The CBZ-doses given ranged from 200 to 1 400 mg/day, the mean being 733 mg/day. In six courses of treatment, patients experienced complete or almost complete pain relief, achieved at CBZ-plasma-concentrations of 24-43 mumol/l. Patients with high pain-scores at plasma-concentrations of 30 mumol/l did not benefit from further dose increase. Small adjustments of plasma-concentration otherwise resulted in pronounced changes in pain-score. Side-effects were not reported below 34 mumol/l. No conclusions could be drawn as to the possible clinical effect of CBZ-10,11-epoxide.</p>","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"31 ","pages":"45-6"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17986734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of clonidine in the treatment of migraine: a review of the literature and personal experience.","authors":"H Hakkarainen, E Kokkanen, T Kallanranta","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76782,"journal":{"name":"Upsala journal of medical sciences. Supplement","volume":"31 ","pages":"16-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18054448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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