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Annual review of cell biology最新文献

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ABC transporters: from microorganisms to man. ABC转运体:从微生物到人。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.000435
C F Higgins
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引用次数: 3811
Actin filaments, stereocilia, and hair cells: how cells count and measure. 肌动蛋白丝、纤毛和毛细胞:细胞如何计数和测量。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.001353
L G Tilney, M S Tilney, D J DeRosier
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引用次数: 292
The role of p34 kinases in the G1 to S-phase transition. p34激酶在G1期到s期转变中的作用。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.002525
S I Reed
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引用次数: 286
The differentiating intestinal epithelial cell: establishment and maintenance of functions through interactions between cellular structures. 分化的肠上皮细胞:通过细胞结构间的相互作用建立和维持功能。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.001105
D Louvard, M Kedinger, H P Hauri
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引用次数: 280
Retroviral reverse transcription and integration: progress and problems. 逆转录逆转录与整合:进展与问题。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.001423
J M Whitcomb, S H Hughes
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引用次数: 206
Structural framework for the protein kinase family. 蛋白激酶家族的结构框架。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.002241
S S Taylor, D R Knighton, J Zheng, L F Ten Eyck, J M Sowadski
In this review, we have summarized the general structural features of the catalytic subunit of cAMP-dependent protein kinase, emphasizing those features that will very likely be conserved in all members of the protein kinase family. The overall secondary structure of the catalytic core will probably be conserved throughout the catalytic core, as will the active site regions associated with MgATP binding and catalysis. The mechanisms for activation and the role of protein phosphorylation are unique for each kinase. The structure of the catalytic subunit now provides a general framework for modeling other protein kinases. Although this is no substitute for a crystal structure for each protein kinase, this one structure, nevertheless, does provide major insights to the molecular organization of each of these enzymes.
在这篇综述中,我们总结了camp依赖性蛋白激酶催化亚基的一般结构特征,强调了这些特征很可能在所有蛋白激酶家族成员中都是保守的。催化核心的整体二级结构可能在整个催化核心中被保留,与MgATP结合和催化相关的活性位点区域也将被保留。每种激酶的活化机制和磷酸化作用都是独特的。催化亚基的结构现在为其他蛋白激酶的建模提供了一个总体框架。虽然这不能代替每个蛋白激酶的晶体结构,但这一结构确实为这些酶的分子组织提供了重要的见解。
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引用次数: 313
Hox codes and positional specification in vertebrate embryonic axes. 脊椎动物胚胎轴的Hox编码和位置规范。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.001303
P Hunt, R Krumlauf

We have compared the ways in which vertebrate Hox genes are used in the patterning of three distinct embryonic contexts, the branchial region, the somites, and the limb. We have identified common features of the three systems, but have suggested on the basis of their differences (in both embryological properties and use of Hox genes) that it is better to consider each as an independent system for regional specification. Nevertheless, there are sufficient common features to expect that exploitation of the distinct experimental advantages of each system will provide important insights to the mode of operation of the others.

我们比较了脊椎动物Hox基因在三种不同的胚胎环境(鳃区、体和肢体)中形成模式的方式。我们已经确定了这三个系统的共同特征,但根据它们的差异(在胚胎学特性和Hox基因的使用方面),我们建议最好将每个系统视为一个独立的区域规范系统。然而,有足够的共同特征,可以期望利用每个系统的独特实验优势,将为其他系统的操作模式提供重要的见解。
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引用次数: 151
Nuclear-encoded transfer RNAs in plant mitochondria. 植物线粒体中的核编码转移rna。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.000555
A Dietrich, J H Weil, L Maréchal-Drouard
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引用次数: 91
Genetic approaches to molecular motors. 分子马达的遗传方法。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.000333
S A Endow, M A Titus
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引用次数: 77
Post-transcriptional steps in the expression of chloroplast genes. 叶绿体基因表达的转录后步骤。
Pub Date : 1992-01-01 DOI: 10.1146/annurev.cb.08.110192.000245
J D Rochaix
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引用次数: 130
期刊
Annual review of cell biology
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