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Clinical reviews in allergy最新文献

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Cetirizine. An updated review of its pharmacological properties and therapeutic efficacy. 西替利嗪。其药理性质和治疗效果的最新综述。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02802294
J P Rihoux, S Mariz
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引用次数: 18
Loratadine. A review of recent findings in pharmacology, pharmacokinetics, efficacy, and safety, with a look at its use in combination with pseudoephedrine. 氯雷他定。回顾最近在药理学、药代动力学、疗效和安全性方面的发现，并研究其与伪麻黄碱联合使用的情况。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02802295
I J Roman, M R Danzig

Antihistamines are considered first-line therapy for the relief of symptoms from allergic rhinitis and chronic urticaria. The newer, second-generation, nonsedating antihistamines reduce the central nervous system and anticholinergic side effects commonly found with previous drugs. The availability of H1-receptor antagonists that produce therapeutic effects without causing unwanted CNS effects fulfills an important practical need, since these drugs are clearly preferable in patients who drive or operate heavy machinery, or who are involved in activities requiring full alertness. Physicians and patients alike are pleased with the efficacy and safety the second-generation antihistamines bring to the treatment of allergy symptoms. Loratadine is an especially effective second-generation H1-receptor antagonist and is comparable to many of the other second-generation antihistamines. Loratadine may be particularly advantageous because of its low dose and the convenience of once-daily dosing. A more subtle advantage, loratadine's antiallergic properties, may warrant its use for specific treatment situations as future research clarifies the nature of the inflammatory response and the mechanisms of action antiallergic antagonists have in this regard.

抗组胺药被认为是缓解过敏性鼻炎和慢性荨麻疹症状的一线疗法。较新的，第二代，非镇静抗组胺药减少中枢神经系统和抗胆碱能的副作用，通常发现与以前的药物。h1受体拮抗剂既能产生治疗效果，又不会对中枢神经系统造成不良影响，这满足了一项重要的实际需求，因为这些药物显然更适合驾驶或操作重型机械的患者，或者需要高度警觉的患者。医生和患者都对第二代抗组胺药治疗过敏症状的有效性和安全性感到满意。氯雷他定是一种特别有效的第二代h1受体拮抗剂，与许多其他第二代抗组胺药相当。氯雷他定可能特别有利，因为它的低剂量和每日一次给药的方便。一个更微妙的优势，氯雷他定的抗过敏特性，可能保证其用于特定的治疗情况，因为未来的研究阐明了炎症反应的性质和抗过敏拮抗剂在这方面的作用机制。
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引用次数: 25
IgE mediated allergy to natural rubber latex in 100 patients. IgE介导的天然胶乳过敏100例。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02914420
C Pecquet, F Leynadier
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引用次数: 14
Introduction. Second-generation antihistamines. 介绍。第二代抗组胺药。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02802291
M M Janssens
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引用次数: 2
Clinical features of atopic dermatitis. 特应性皮炎的临床特点。
Clinical reviews in allergy
Pub Date : 1993-01-01
A S Paller
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引用次数: 0
The role of allergens in atopic dermatitis. 过敏原在特应性皮炎中的作用。
Clinical reviews in allergy
Pub Date : 1993-01-01
S M Jones, H A Sampson

AD is a disorder that affects up to 12% of the pediatric population. This disease is multifactorial and encompasses a wide array of etiologic factors. Strong evidence has existed in the literature over the past century for the role of inhalant and food allergies in the pathogenesis of AD. Much work is currently ongoing to delineate the role of individual cellular components, cytokines, and other mediators in the pathogenesis of AD. The answers to these questions, as well as a more comprehensive understanding of hereditary factors, will provide key information to our overall understanding of AD and our ability to treat patients with this disease more effectively in the future.

阿尔茨海默病是一种影响多达12%儿科人口的疾病。这种疾病是多因素的，包括一系列广泛的病因。在过去一个世纪的文献中，有强有力的证据表明吸入剂和食物过敏在AD发病机制中的作用。目前正在进行大量的工作来描述个体细胞成分、细胞因子和其他介质在AD发病机制中的作用。这些问题的答案，以及对遗传因素的更全面的了解，将为我们全面了解阿尔茨海默病以及我们将来更有效地治疗这种疾病的能力提供关键信息。
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引用次数: 0
Measuring reduction of the allergenicity of latex gloves. 乳胶手套致敏性降低的测定。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02914423
J E Autegarden
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引用次数: 3
Allergic contact dermatitis to rubber. Clinical aspects and main allergens. 橡胶过敏性接触性皮炎。临床方面及主要过敏原。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02914424
C Pecquet
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引用次数: 1
Astemizole. A nonsedating antihistamine with fast and sustained activity. 阿司咪唑。一种非镇静的抗组胺药，具有快速和持续的活性。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02802293
M M Janssens
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引用次数: 25
Composition of synthetic latexes used for manufacturing gloves by dipping processes. 用浸渍工艺制造手套的合成乳胶的组成。
Clinical reviews in allergy
Pub Date : 1993-01-01 DOI: 10.1007/BF02914418
M Y Renaud
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引用次数: 2
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