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Cannabis Use in Pregnancy Is Associated With an Increased Incidence of Low Birth Weight and Small-for-Gestational-Age Infants. 孕期吸食大麻与低出生体重儿和小于胎龄儿的发生率增加有关。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Linda Speer
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引用次数: 0
Case Report: Small Bowel Obstruction After Starting Tirzepatide (Mounjaro). 病例报告:开始使用替扎帕肽(Mounjaro)后出现小肠梗阻。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Leandra Morgenthaler, Regina DePietro
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引用次数: 0
Painful Finger Lesion. 手指病变疼痛。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Allison Vogl, Carlie Hoffman, Emeil Shenouda
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引用次数: 0
Painless Black Toe. 无痛黑脚趾。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Nolan E Lee, Arielle Ilano, Ha Kirsten Do, Maylynn Tam
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引用次数: 0
Weight Loss in Patients With Overweight or Obesity and Knee Osteoarthritis. 超重或肥胖与膝骨关节炎患者的体重减轻。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Thomas Troy, Hanh Ngo, Lauren Pham
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引用次数: 0
Acute Abdominal Pain in Children: Evaluation and Management. 儿童急性腹痛:评估与处理。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Katie L Buel, James Wilcox, Paul T Mingo

Acute abdominal pain in children is a common presentation in the clinic and emergency department settings and accounts for up to 10% of childhood emergency department visits. Determining the appropriate disposition of abdominal pain in children can be challenging. The differential diagnosis of acute abdominal pain, including gastroenteritis, constipation, urinary tract infection, acute appendicitis, tubo-ovarian abscess, testicular torsion, and volvulus, and the diagnostic approach vary by age. Most causes of acute abdominal pain in children are self-limited. Symptoms and signs that indicate referral for surgery include pain that is severe, localized, and increases in intensity; pain preceding vomiting; bilious vomiting; hematochezia; guarding; and rigidity. Physical examination findings suggestive of acute appendicitis in children include decreased or absent bowel sounds, psoas sign, obturator sign, Rovsing sign, and right lower quadrant rebound tenderness. Initial laboratory evaluation may include urinalysis; complete blood cell count; human chorionic gonadotropin, lactate, and C-reactive protein levels; and a comprehensive metabolic profile. Ultrasonography, including point-of-care ultrasonography, for the evaluation of acute abdominal pain in children is the preferred initial imaging modality due to its low cost, ease of use, and lack of ionizing radiation. In addition to laboratory evaluation and imaging, children with red-flag or high-risk symptoms should be referred for urgent surgical consultation. Validated scoring systems, such as the Pediatric Appendicitis Score, can be used to help determine the patient's risk of appendicitis.

儿童急性腹痛是临床和急诊科常见的症状,占儿童急诊科就诊的10%。确定儿童腹痛的适当处置可能具有挑战性。急性腹痛的鉴别诊断包括胃肠炎、便秘、尿路感染、急性阑尾炎、输卵管卵巢脓肿、睾丸扭转和扭转,诊断方法因年龄而异。儿童急性腹痛的大多数原因是自限性的。提示转介手术的症状和体征包括严重、局部和强度增加的疼痛;呕吐前的疼痛;胆汁呕吐;便血;守卫;和刚度。提示儿童急性阑尾炎的体格检查结果包括肠音减少或消失、腰肌征、闭孔征、旋转征和右下腹反跳压痛。初步实验室评估可能包括尿液分析;全血细胞计数;人绒毛膜促性腺激素、乳酸和c反应蛋白水平;和一个全面的代谢档案。超声检查,包括即时超声检查,是评估儿童急性腹痛的首选初始成像方式,因为其成本低,使用方便,缺乏电离辐射。除了实验室评估和影像学检查外,有危险症状或高危症状的儿童应进行紧急外科会诊。经过验证的评分系统,如小儿阑尾炎评分,可用于帮助确定患者患阑尾炎的风险。
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引用次数: 0
Correction. 更正。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
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引用次数: 0
Bone Stress Injuries: Diagnosis and Management. 骨应力损伤:诊断和治疗。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Jeremy D Schroeder, Steven D Trigg, Gerardo E Capo Dosal

Bone stress injuries (BSIs) are a spectrum of overuse injuries caused by an accumulation of microdamage, from high physical demands on normal bone or normal physiologic loads on structurally compromised bone. They typically result from overuse in younger patients but are also caused by pathologic bone conditions, including relative energy deficiency in sport, which features decreased bone mineral density. Stress fractures, representing 20% of BSIs, are the most severe type and feature discernable sclerosis or fracture lines on imaging. Without treatment, they can progress to complete fractures. BSIs present as localized pain and loss of function, most often in the setting of sudden load volume changes. Palpatory bony tenderness is the most significant examination finding. Prevention focuses on recognition and optimization of modifiable risk factors, which include nutritional, lifestyle, and physical activity habits. Despite low sensitivity, radiography should be the initial imaging modality for suspected BSI. Magnetic resonance imaging is the preferred definitive study. Point-of-care ultrasonography is gaining popularity, but training and availability are barriers in primary care. Once a BSI is diagnosed, early intervention is imperative to reduce pain and promote healing. Severity of BSI (grade) and location (low- vs high-risk of complications) guide the management approach. Injuries in low-risk sites are treated conservatively, whereas fractures in high-risk sites warrant consultation with sports medicine or orthopedics. Femoral neck BSIs, especially when tension-sided, require urgent surgical consultation.

骨应激损伤(bsi)是由于对正常骨骼的高物理要求或对结构受损的骨骼的正常生理负荷造成的微损伤积累而引起的过度使用损伤。它们通常是由年轻患者过度使用造成的,但也由病理性骨骼状况引起,包括运动时相对能量不足,其特征是骨密度降低。应力性骨折占bsi的20%,是最严重的类型,影像学上表现为可识别的硬化或骨折线。如果不进行治疗,它们会发展为完全骨折。bsi表现为局部疼痛和功能丧失,最常发生在负荷容量突然变化的情况下。触诊骨压痛是最重要的检查发现。预防的重点是识别和优化可改变的风险因素,包括营养、生活方式和体育活动习惯。尽管灵敏度较低,对于疑似BSI, x线摄影应作为首选影像学检查方式。磁共振成像是首选的确定研究。即时超声检查越来越受欢迎,但培训和可用性是初级保健的障碍。一旦诊断出BSI,早期干预是必要的,以减少疼痛和促进愈合。BSI的严重程度(分级)和位置(并发症的低vs高风险)指导治疗方法。低风险部位的损伤需保守治疗,而高风险部位的骨折需咨询运动医学或骨科。股骨颈bsi,特别是当张力侧,需要紧急外科会诊。
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引用次数: 0
SGLT-2 Inhibitors for Individuals With Diabetes and Chronic Kidney Disease. 糖尿病和慢性肾脏疾病患者的SGLT-2抑制剂
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Michael D North, Alexei O DeCastro
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引用次数: 0
Over 13.6 Years, Children With Hypertension Are Twice As Likely to Have Major Adverse Cardiovascular Events. 13.6 岁以上儿童高血压患者发生重大不良心血管事件的几率是正常儿童的两倍。
IF 3.8 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-12-01
Henry C Barry
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引用次数: 0
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American family physician
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