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Diagnostic and prognostic applications of flow cytometry in pleuro-pulmonary neoplasms. 流式细胞术在胸膜肺肿瘤诊断及预后中的应用。
Sarcoidosis
Pub Date : 1993-09-01
F Perna, P Giacomelli, F Stefanelli, A Volpe, A Ponticiello, N Az-Zeqeh, G Antinolfi, F Bariffi
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引用次数: 0
Pulmonary Langerhans' cell granulomatosis (LCG). 肺朗格汉斯细胞肉芽肿(LCG)。
Sarcoidosis
Pub Date : 1993-09-01
W J Williams, D G James

Pulmonary Langerhans' granulomatosis (LCG) is characterised by infiltration of peripheral airways by dendritic cell precursors and Langerhans' cells (LC) together with eosinophils and mixed chronic inflammatory cells. Consequent airways destruction commonly leads to cystic changes and frequent pneumothorax. LC's are best identified by the electron microscope finding of Birbeck granules. Immunocytochemical markers are also of value. They are frequent in the early stages though absent in end stage disease. LCG is distinguished from sarcoidosis by the absence of epithelioid cell granulomas, association with heavy cigarette smoking in young males and frequency of pneumothorax. Both diseases show lymphocytosis in bronchoalveolar lavage but differ in that LCG shows a predominance of T-suppressor cells and sarcoidosis an excess of T-helper cells.

肺朗格汉斯肉芽肿病(LCG)的特征是树突状细胞前体和朗格汉斯细胞(LC)以及嗜酸性粒细胞和混合慢性炎症细胞浸润周围气道。随之而来的气道破坏通常会导致囊性改变和频繁的气胸。LC的最佳鉴定方法是在电子显微镜下发现Birbeck颗粒。免疫细胞化学标记物也有价值。它们常见于早期，但在终末期疾病中不存在。LCG与结节病的区别在于没有上皮样细胞肉芽肿，与年轻男性大量吸烟和气胸的频率有关。两种疾病均表现为支气管肺泡灌洗时淋巴细胞增多，但不同之处在于LCG表现为t抑制细胞为主，结节病表现为t辅助细胞过多。
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引用次数: 0
Sarcoidosis--the way ahead. 结节病——前方的路。
Sarcoidosis
Pub Date : 1993-09-01
D G Jones

The cause(s) of sarcoidosis is likely to be a combination of a conducive soil or sarcoid diathesis invaded by an antigen-driven cell-mediated immune response. The antigenic invasion may be mycobacteria and other organisms and/or their chemical constituents. A ten-point plan of management is set out so that early diagnosis allows early treatment and to prevent complicating pulmonary, ocular or renal fibrosis and to prevent failure of these vital organs.

结节病的病因可能是抗原驱动的细胞介导的免疫反应侵入有益的土壤或结节素质的组合。抗原入侵可能是分枝杆菌和其他生物体和/或它们的化学成分。制定了十点管理计划，以便及早诊断，及早治疗，防止并发肺、眼或肾纤维化，防止这些重要器官衰竭。
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引用次数: 0
HLA Class I, II and III polymorphisms in sarcoidosis. 结节病患者HLA I、II和III类多态性。
Sarcoidosis
Pub Date : 1993-09-01
M Luisetti, M Martinetti, M Cuccia, L Pasturenzi, A Cipriani, G Semenzato, C Grassi
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引用次数: 0
Alveolar inflammation in pulmonary sarcoidosis: cells and mediators. 肺结节病的肺泡炎症:细胞和介质。
Sarcoidosis
Pub Date : 1993-09-01
E Pozzi, P Ghio, I Mabritto, P Solidoro, G Selvaggi, L Marchetti, C Albera
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引用次数: 0
Selection of Valpha 2.3 cells in the lung of patients with sarcoidosis. 结节病患者肺瓣膜2.3细胞的筛选。
Sarcoidosis
Pub Date : 1993-09-01
A Cerutti, L Trentin, R Zambello, P Bulian, A Milani, C Enthammer, R Sancetta, A Cipriani, C Agostini, G Sememzato
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引用次数: 0
Role of magnetic resonance imaging in neurosarcoidosis. 磁共振成像在神经结节病中的作用。
Sarcoidosis
Pub Date : 1993-09-01
J K Kadakia, P M Collette, O P Sharma

Central nervous system (CNS) involvement in Sarcoidosis poses a difficult diagnostic problem for the clinician. Neurologic involvement may occur long before the onset of symptoms. Contrast enhanced computerized tomography does not always reveal parenchymal and meningeal involvement. Recently gadolinium enhanced Magnetic Resonance Imaging has shown increased sensitivity in detecting CNS involvement. These findings however are not specific for sarcoidosis and one must consider appropriate clinical circumstances in arriving at the diagnosis.

结节病累及中枢神经系统(CNS)是临床诊断的难题。神经系统受累可能早在症状出现之前就已发生。增强计算机断层扫描并不总是显示实质和脑膜受累。最近钆增强磁共振成像在检测中枢神经系统受累方面显示出更高的灵敏度。然而，这些发现并不是结节病所特有的，在诊断时必须考虑适当的临床情况。
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引用次数: 0
Calcium-phosphorus metabolism in sarcoidosis. 结节病中的钙磷代谢。
Sarcoidosis
Pub Date : 1993-09-01
M Montagnani, S Gonnelli, F Zacchei, P Rottoli, S Solitro, C Cepollaro, R Palmieri, M Montomoli, D Borracelli, C Pondrelli
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引用次数: 0
Immunohistochemical detection of microenvironmental abnormalities in lung biopsies from patients with sarcoidosis. 结节病患者肺活检微环境异常的免疫组化检测。
Sarcoidosis
Pub Date : 1993-09-01
M Chilosi, F Menestrina, M Lestani, A Cipriani, F Pomponi, M Angi, F Adami, G Semenzato
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引用次数: 0
Why perform high resolution computed tomography in pulmonary sarcoidosis? 为什么对肺结节病进行高分辨率计算机断层扫描?
Sarcoidosis
Pub Date : 1993-09-01
M Savini, G Bertorelli, S Viani, V Bocchino, A Zollino, E Marangio, D Oliveri
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引用次数: 0
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