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Alcoholic women in treatment: early histories and early problem behaviors. 接受治疗的酗酒妇女:早期病史和早期问题行为
Pub Date : 1989-01-01 DOI: 10.1300/J251v08n02_08
E S Gomberg

When data from interviews with 301 alcoholic women, drawn from 21 treatment facilities, are compared with interview responses of 137 age-matched nonalcoholic control women, differences in report of early life experience appear. The two groups of women do not differ significantly in report of painful early life events, but they do differ significantly in reports of response to these events and their affective reactions during their early years. Clinic and Control women also differ significantly in report of impulsive childhood and adolescent behaviors. Comparison of Clinic women of different ages with nonalcoholic age peers suggest that childhood and adolescent impulse control problems are more likely to be associated with earlier onset of alcoholism. Present data are based on retrospection and self-report. Assuming that alcoholic women introduce no more memory distortions than nonalcoholic women in evoking early life memories, the consistent finding is that early life emotional/behavioral problems are reported to a significantly greater extent by women who will later become alcoholic than by those who will not.

当对来自21个治疗机构的301名酗酒妇女的访谈数据与137名年龄匹配的非酗酒对照妇女的访谈反应进行比较时,早期生活经历的报告出现了差异。这两组女性在早期生活痛苦事件的报告上没有显著差异,但在对这些事件的反应和她们早年的情感反应的报告上却有显著差异。临床女性和对照组女性在童年和青少年冲动行为的报告上也存在显著差异。不同年龄的临床妇女与非酒精年龄的同龄人的比较表明,童年和青少年的冲动控制问题更可能与早期酗酒有关。目前的数据是基于回顾和自我报告。假设酗酒的女性在唤起早期生活记忆时不会比不酗酒的女性带来更多的记忆扭曲,一致的发现是,后来成为酗酒者的女性比那些不成为酗酒者的女性报告的早期生活情感/行为问题的程度要大得多。
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引用次数: 19
Predictor variables of adolescent drinking. 青少年饮酒的预测变量。
Pub Date : 1989-01-01 DOI: 10.1300/J251v08n02_06
M A Forney, P D Forney, W K Ripley

A survey was conducted to determine which socio-cultural and psychosocial variables had the ability to discriminate adolescent drinking behavior at four different age groups. A total of 3,017 sixth, eighth, tenth, and twelfth grade students in the Southeast participated in the study. Those students who were classified as moderate to heavy drinkers were more likely to be White, male, had higher scores on an alcohol knowledge test, were more liberal in their attitudes toward alcohol use, drank at an earlier age, and had friends who drank. When all predictor variables were considered as a group, the two most predominant characteristics for explaining student drinking behavior were peer behavior and attitudes toward alcohol. Parental drinking behaviors were significant for the younger students, but compared to the peer and attitude variables, their contributions to group separation were minor. Efforts to curb moderate or heavy drinking among adolescents should focus on the peer influences of adolescent drinking and related risk factors associated with problem drinking.

进行了一项调查,以确定哪些社会文化和社会心理变量能够区分四个不同年龄组的青少年饮酒行为。东南地区共有3017名六年级、八年级、十年级和十二年级的学生参加了这项研究。那些被归类为中度到重度饮酒者的学生更有可能是白人男性,他们在酒精知识测试中得分更高,对酒精使用的态度更自由,饮酒年龄更早,并且有饮酒的朋友。当所有预测变量被视为一个群体时,解释学生饮酒行为的两个最主要特征是同伴行为和对酒精的态度。父母饮酒行为对低年级学生有显著影响,但与同伴和态度变量相比,父母饮酒行为对群体分离的影响较小。遏制青少年中度或重度饮酒的努力应侧重于青少年饮酒对同伴的影响以及与问题饮酒相关的相关风险因素。
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引用次数: 25
National and international strategies to control drug abuse. 管制药物滥用的国家和国际战略。
Pub Date : 1989-01-01 DOI: 10.1300/J251v08n02_01
J Westermeyer

Since drug problems continue to produce health problems in our society, it is important to understand world-wide issues favoring the continued existence of drug abuse. National decisions to attack the problem at the production end outside the U.S. have been viewed as being more efficient, more effective, less disruptive and less expensive than approaches to reduce consumption within our own boundaries. This review aims at clarifying the issues involved in national versus international strategies against drugs.

由于毒品问题继续在我们的社会中造成健康问题,了解有利于药物滥用继续存在的世界范围问题是很重要的。在美国以外的生产端解决这个问题的国家决定被认为比在我们自己的边界内减少消费的方法更有效率,更有效,破坏性更小,成本更低。本审查的目的是澄清国家与国际禁毒战略所涉及的问题。
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引用次数: 6
Substance abuse and international travel. 药物滥用和国际旅行。
Pub Date : 1989-01-01 DOI: 10.1300/J251v08n02_02
W R Lange, B A McCune

Travel for both business and pleasure can be a risk factor for substance abuse problems, for clinical deterioration in those with chemical dependence, and for relapse when an addiction has been in remission. Sedatives, opioids and alcohol can complicate many of the physiologic adjustments mandated by modern jet travel, such as adaptation to different altitudes, climates, and time zones. Additionally, substances of abuse can result in a deterioration of many clinical conditions during travel, and they can precipitate other medical problems while underway, including motion sickness, heat-related illness and diarrheal disease. Drugs and alcohol are crucial factors in both serious accidents and legal difficulties while traveling. Finally, involvement with drugs as well as close and intimate liaison with drug abusers and their consorts has associated with it a high degree of risk for exposure to serious infectious diseases worldwide.

商务旅行和娱乐旅行都可能成为药物滥用问题的风险因素,对那些有化学依赖的人的临床恶化,以及在成瘾缓解后复发的风险因素。镇静剂、阿片类药物和酒精会使现代喷气式飞机旅行所要求的许多生理调整复杂化,例如适应不同的高度、气候和时区。此外,滥用药物会导致旅行期间许多临床状况恶化,还会在旅途中引发其他医疗问题,包括晕车、与热有关的疾病和腹泻。在旅行中,毒品和酒精是造成严重事故和法律困难的关键因素。最后,吸毒以及与药物滥用者及其同伙的密切和亲密联系,使其具有在世界范围内接触严重传染病的高度风险。
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引用次数: 4
Monitoring recovery from substance abuse: rationales, methods and challenges. 监测药物滥用后的恢复:理由、方法和挑战。
Pub Date : 1989-01-01 DOI: 10.1300/J251v08n01_07
J Westermeyer
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引用次数: 5
Heterosexual contacts of intravenous drug abusers: implications for the next spread of the AIDS epidemic. 静脉注射吸毒者的异性接触:对艾滋病流行病下一次传播的影响。
Pub Date : 1988-03-10 DOI: 10.1300/J251V07N02_08
D. Murphy
There is a scarcity of knowledge about the sexual behavior patterns of the intravenous drug abuser (IVDA), despite the potential role of this group in the heterosexual transmission of AIDS. Using a representative sample of 93 clients from the Addiction Research and Treatment Corporation (ARTC), who consented to be anonymously interviewed, this study investigated sexual behavior patterns and practices of these intravenous drug abusers. Over half of the 758 sexual contacts reported by this sample were non-IVDAs. Results indicated that IVDA males in comparison with IVDA females reported a significantly greater percentage of heterosexual contacts which were non-IVDAs. However, when controlling for needle sharing, this association was significant only for those who shared. The findings indicate the importance of targeting, not only IVDAs with regards to health educational interventions, but also sexually active non-IVDAs, especially females, in communities where intravenous drug abuse is prevalent.
静脉注射吸毒者(IVDA)的性行为模式知识匮乏,尽管这一群体在艾滋病的异性传播中扮演着潜在的角色。本研究使用来自成瘾研究和治疗公司(ARTC)的93名客户的代表性样本,他们同意匿名采访,调查这些静脉注射药物滥用者的性行为模式和做法。该样本报告的758次性接触中,超过一半是非ivda。结果表明,与IVDA女性相比,IVDA男性报告的非IVDA异性恋接触的比例明显更高。然而,当控制共用针头时,这种关联仅对那些共用针头的人有意义。研究结果表明,在静脉注射药物滥用普遍存在的社区,不仅针对静脉注射药物滥用者进行健康教育干预,而且针对性活跃的非静脉注射药物滥用者,特别是女性,也很重要。
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引用次数: 33
To test or not to test: the value of routine testing for antibodies to the human immunodeficiency virus (HIV). 检测或不检测:人类免疫缺陷病毒(HIV)抗体常规检测的价值。
Pub Date : 1988-03-10 DOI: 10.1300/J251V07N02_04
B. Stimmel
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引用次数: 9
Neurocognitive impairment in alcoholics: review and comparison with cognitive impairment due to AIDS. 酗酒者的神经认知障碍:与艾滋病引起的认知障碍的回顾和比较。
Pub Date : 1988-03-10 DOI: 10.1300/J251V07N02_10
M. Pohl
This review indicates that cognitive dysfunction and dementia, specifically caused by chronic alcohol use, consist of subtle changes in cognition which are easily missed and/or forgotten. The nature of the dysfunction and specific neuropsychiatric and neurodiagnostic tests will be reviewed. There are important treatment implications regarding these subtle changes in mental function. Treatment implications will also be summarized. Finally, a comparison will be made between the cognitive impairment experience by patients with Acquired Immune Deficiency Syndrome from that experienced by alcoholics.
这篇综述表明,认知功能障碍和痴呆,特别是由慢性酒精使用引起的,由认知的细微变化组成,这些变化很容易被忽视和/或遗忘。功能障碍的性质和特定的神经精神和神经诊断测试将被审查。对于这些心理功能的细微变化,有重要的治疗意义。治疗的影响也将被总结。最后,将获得性免疫缺陷综合征患者与酗酒者的认知障碍经历进行比较。
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引用次数: 3
Pharmacological issues in alcohol and substance abuse. 酒精和药物滥用的药理学问题。
Pub Date : 1988-02-05 DOI: 10.1300/J251v07n01_07
Lynn Kasner Morgan Mls, J. Raper
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引用次数: 0
Clonidine and alcohol withdrawal. 可乐定和酒精戒断。
Pub Date : 1988-02-05 DOI: 10.1300/J251V07N01_02
P. Cushman
Clonidine attenuates opiate withdrawal syndrome, via reduction in catecholamine activity in the brain, most probably at the locus ceruleus. Clonidine and locus ceruleus lesions, in animals with alcohol dependency as with the opiates, modify alcohol withdrawal. Both alcohol loading and withdrawal from steady alcohol use alter catecholamines in man and animals. Clonidine's potential to treat alcoholics in withdrawal is reviewed. Several double blind studies showed clonidine, or similar analogues, to be somewhat superior to placebo in acute alcohol withdrawal. Major improvements were in pulse, blood pressure and composite alcohol withdrawal scores. Side effects were minor and mainly included mild sedation, or postural hypotension. In the only available published study clonidine compared reasonably well to a standard sedative in alcohol withdrawal, and greatly influential in plasma catecholamine levels. Other components of alcohol withdrawal, as seizures and hallucinations-delirium tremens have not been documented to change with clonidine. The alpha-2-adrenergic agonists in alcohol treatment seemed modestly effective for treatment of some parts of alcohol withdrawal. They represent a promising, novel, but still investigational approach. Additional data, particularly comparing them to the benzodiazepines, are needed before their potential in therapeutics can be assessed.
可乐定通过降低大脑中儿茶酚胺的活性来减轻阿片戒断综合征,最可能的是在蓝斑处。酒精依赖动物与阿片类药物一样,可乐定和蓝斑损伤可改变酒精戒断。酒精负荷和从稳定的酒精使用中退出都会改变人和动物体内的儿茶酚胺。对可乐定治疗戒断性酗酒的潜力进行了综述。几项双盲研究表明,可乐定或类似的类似物在急性酒精戒断中比安慰剂更有效。主要的改善是在脉搏、血压和综合戒酒评分方面。副作用轻微,主要包括轻度镇静或体位性低血压。在唯一一项已发表的研究中,可乐定与标准的酒精戒断镇静剂相比效果相当好,并且对血浆儿茶酚胺水平有很大影响。酒精戒断的其他症状,如癫痫发作和幻觉-震颤性谵妄,并没有文献记载因可乐定而改变。在酒精治疗中,α -2-肾上腺素能激动剂似乎对某些部分的酒精戒断有适度的疗效。它们代表了一种有前途的、新颖的、但仍处于研究阶段的方法。在评估其治疗潜力之前,需要更多的数据,特别是将其与苯二氮卓类药物进行比较。
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引用次数: 27
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Advances in alcohol & substance abuse
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