Two hundred thirty patients with cysticercosis were reviewed. Investigation with CT scan has led to a more detailed understanding of the natural history of human infestation which is essential to the evaluation of new pharmacological and neurosurgical treatments. In contrast to reports emphasizing the need to extirpate all intraventricular cysts, many of our patients needed only ventricular shunt implantation. The ability to evaluate and reevaluate hydrocephalus by CT scan permitted comfortable use of ventricular shunt insertion as the only treatment. Nevertheless, cysts in the fourth ventricle should nearly always be extirpated, because these cysts, by their mass effect, may cause herniation even after shunt implantation. Serious morbidity and death occur chiefly in patients who develop hydrocephalus from intraventricular and basilar infestation. It is unlikely that praziquantel will be effective in patients who present with symptoms of hydrocephalus.
{"title":"Cysticercosis--review of 230 patients.","authors":"G F McCormick","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two hundred thirty patients with cysticercosis were reviewed. Investigation with CT scan has led to a more detailed understanding of the natural history of human infestation which is essential to the evaluation of new pharmacological and neurosurgical treatments. In contrast to reports emphasizing the need to extirpate all intraventricular cysts, many of our patients needed only ventricular shunt implantation. The ability to evaluate and reevaluate hydrocephalus by CT scan permitted comfortable use of ventricular shunt insertion as the only treatment. Nevertheless, cysts in the fourth ventricle should nearly always be extirpated, because these cysts, by their mass effect, may cause herniation even after shunt implantation. Serious morbidity and death occur chiefly in patients who develop hydrocephalus from intraventricular and basilar infestation. It is unlikely that praziquantel will be effective in patients who present with symptoms of hydrocephalus.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 51-year-old woman with an inherited polyneuropathy had fatiguability and a dramatic historical response to prostigmine. Repetitive motor nerve stimulation produced a prominent decrement of the compound muscle action potential in distal muscles with marked facilitation after brief exercise. Defective neuromuscular transmission paralleled the polyneuropathy in distribution and severity. We hypothesize that deficient release of acetylcholine by regenerating or degenerating nerve terminals likely caused the defect of neuromuscular transmission in this patient.
{"title":"Neuromuscular transmission defect in inherited polyneuropathy.","authors":"J J Kelly, G A Baquis, L S Adelman, T L Munsat","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 51-year-old woman with an inherited polyneuropathy had fatiguability and a dramatic historical response to prostigmine. Repetitive motor nerve stimulation produced a prominent decrement of the compound muscle action potential in distal muscles with marked facilitation after brief exercise. Defective neuromuscular transmission paralleled the polyneuropathy in distribution and severity. We hypothesize that deficient release of acetylcholine by regenerating or degenerating nerve terminals likely caused the defect of neuromuscular transmission in this patient.</p>","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14154498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Somatostatin in cerebrospinal fluid.","authors":"P E Cooper","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14013797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HLA and complement studies in Alzheimer's disease.","authors":"C M Hulette, R L Walford","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15032523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Brain biopsy in Alzheimer's disease: surgical technique and indications.","authors":"R E Harbaugh","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P D Lyden, J Seelig, R P Martin, S Yoshida, M Bailey, J F Rothrock, J A Alksne
{"title":"A new model of focal cerebral ischemia: validation and utility.","authors":"P D Lyden, J Seelig, R P Martin, S Yoshida, M Bailey, J F Rothrock, J A Alksne","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The diagnosis of dementia of the Alzheimer type (DAT) depends on the clinician's ability to document intellectual impainnent in the patient and to exclude other causes of dementia. About 50% of all demented patients entering a hospital are ultimately found at postmortem examination to have Alzheimer's disease. However, using the most rigorous criteria the accuracy of correct clinical diagnosis at autopsy approaches only 80-90% and this excludes some unusual patients. Most investigators use the Diagnostic and Statistical Manual of Mental Disorder-third ed. (DSM-III) criteria for dementia, a rating of perfonnance in activities of daily living, and an assessment of personality and intellectual function for diagnosis. Two clinical rating scales: the Blessed Dementia Rating Scale (parts 1 and 2) and the Clinical Dementia Rating Scale, are used frequently and seem to identify patients with DAT with greater accuracy than other scales. Our assessment protocol for dementia includes a quantitative neurological examination because certain motor manifestations have been observed in DAT: myoclonus, rigidity, stooped posture, and bradykinesia. We found these clinical features to be useful in predicting the course in some patients. Our data indicate clinical heterogeneity in DAT and may suggest the presence of unique subgroups.
{"title":"Heterogeneity and prognosis in dementia of the Alzheimer type.","authors":"R. Mayeux, Y. Stern, M. Sano","doi":"10.7916/D8ZS4CZ8","DOIUrl":"https://doi.org/10.7916/D8ZS4CZ8","url":null,"abstract":"The diagnosis of dementia of the Alzheimer type (DAT) depends on the clinician's ability to document intellectual impainnent in the patient and to exclude other causes of dementia. About 50% of all demented patients entering a hospital are ultimately found at postmortem examination to have Alzheimer's disease. However, using the most rigorous criteria the accuracy of correct clinical diagnosis at autopsy approaches only 80-90% and this excludes some unusual patients. Most investigators use the Diagnostic and Statistical Manual of Mental Disorder-third ed. (DSM-III) criteria for dementia, a rating of perfonnance in activities of daily living, and an assessment of personality and intellectual function for diagnosis. Two clinical rating scales: the Blessed Dementia Rating Scale (parts 1 and 2) and the Clinical Dementia Rating Scale, are used frequently and seem to identify patients with DAT with greater accuracy than other scales. Our assessment protocol for dementia includes a quantitative neurological examination because certain motor manifestations have been observed in DAT: myoclonus, rigidity, stooped posture, and bradykinesia. We found these clinical features to be useful in predicting the course in some patients. Our data indicate clinical heterogeneity in DAT and may suggest the presence of unique subgroups.","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71368840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Workshop on early diagnosis in Alzheimer's disease. November 6-7, 1985.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cerebral biopsy in the study of Alzheimer's disease.","authors":"D M Bowen, D Neary","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":77682,"journal":{"name":"Bulletin of clinical neurosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14961592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号