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Treatment of neuroleptic-induced akathisia with propranolol: a controlled replication study. 心得安治疗抗精神病药诱导的静坐症:一项对照重复研究。
M S Kramer, R Gorkin, C DiJohnson

Twelve DSM-IIIR diagnosed schizophrenics, with neuroleptic-induced akathisia (NIA), were treated with either propranolol or matched placebo for two days, followed by a treatment crossover phase for five more days. Raters and patients were "blind" to treatment. This study shows that 120 mg of propranolol a day is more effective than placebo in reducing akathisia, and that propranolol's antiakathisic effect may require several days of treatment.

12名DSM-IIIR诊断的精神分裂症患者,患有抗精神病药诱导的静坐症(NIA),用普萘洛尔或匹配的安慰剂治疗2天,然后再进行5天的治疗交叉期。评分者和患者对治疗“视而不见”。这项研究表明,每天服用120毫克心得安在减轻静坐障碍方面比安慰剂更有效,而且心得安的抗静坐效果可能需要几天的治疗。
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引用次数: 0
Correlations of substance abuse and self-image among socially diverse groups of adolescents and clinical implications. 社会不同群体青少年药物滥用与自我形象的相关性及其临床意义。
V M Uribe, E Ostrov

Two culturally diverse groups of male youths, ages 16-18, were compared with respect to self-image correlates of alcohol and drug use. Self-image was measured through use of the Offer Self-Image Questionnaire (OSIQ), a reliable, well-validated measure of adolescent self-image covering eleven separate areas of functioning. Alcohol and drug use were measured by means of the Delinquency Checklist (DCL), a self-report measure of delinquent behavior first developed by Short and Nye. The adolescents studied were culturally diverse: one group consisted of the entire junior class of an all-male, all-black Roman Catholic Parochial School located in an economically deprived urban neighborhood; the other group comprised a random sample of all the junior and senior boys in an almost all-white, upper-middle-class, suburban public high school. Results showed that in both groups drug use is associated with poor family relationships and impaired self-image. Selling drugs was more prevalent by self-report among the black, inner-city youths than it was among the white, suburban youths. Selling drugs was associated with poor impulse control, relatively low vocational and educational goals and poor coping skills. The research data is discussed in regards to its relevance to therapy of two culturally diverse groups of adolescents.

研究人员比较了两组不同文化背景的16-18岁男性青年与酒精和药物使用之间的自我形象关系。自我形象是通过使用主动自我形象问卷(OSIQ)来测量的,这是一种可靠的、经过充分验证的青少年自我形象测量方法,涵盖了11个独立的功能领域。酒精和药物的使用是通过犯罪清单(DCL)来测量的,这是一种由肖特和奈首先开发的犯罪行为的自我报告测量。被研究的青少年在文化上是多样化的:一组包括位于经济贫困的城市社区的一所全是男性、全是黑人的罗马天主教教区学校的整个低年级;另一组随机选取了一所几乎全是白人、中上层阶级的郊区公立高中的所有初四男生。结果表明,在两组中,吸毒与家庭关系不良和自我形象受损有关。据自述,贩卖毒品在市中心的黑人青年中比在郊区的白人青年中更为普遍。销售毒品与冲动控制能力差、相对较低的职业和教育目标以及较差的应对技能有关。研究数据讨论了其与两种不同文化群体的青少年治疗的相关性。
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引用次数: 0
A case of administrative conflict: observations on the dynamic framework. 行政冲突案例:对动态框架的观察。
O J Thienhaus

A situation is described of suddenly erupting conflict in an interdisciplinary meeting of psychiatric hospital staff. The conflict is related to the systemic impact of recent changes in psychiatric hospital practice. The observed affect and interpersonal dynamics are reviewed in the context of different conceptual frameworks. These include Maslow's hierarchy of needs model, the group focal conflict paradigm and the concept of scapegoating. The use and integration of these three approaches toward understanding affectively laden administrative conflict are discussed. Specific reference is made to the utilization of such understanding in developing leadership skills in a multi-disciplinary mental health setting.

一个情况描述了突然爆发的冲突在一个跨学科会议的精神病院的工作人员。这种冲突与最近精神病院实践变化的系统性影响有关。观察到的情感和人际动力学在不同的概念框架的背景下进行了审查。这些包括马斯洛的需求层次模型,群体焦点冲突范式和替罪羊的概念。本文讨论了这三种方法的使用和整合,以理解充满情感的行政冲突。具体提到在多学科心理健康环境中利用这种理解发展领导技能。
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引用次数: 0
Psychiatrists choosing psychoanalytic training at mid-career. 精神科医生在职业生涯中期选择精神分析培训。
J Goodwin, J Patrick

At one institute 48 percent of physician candidates doing class-work are over 40. This percentage has increased over the past decade, perhaps reflecting new economic constraints and the increased proportion of women candidates. A review of the first training analysis, Freud's, and conversations with some present day candidates indicate that choosing training at mid-career can address specific adult developmental issues, including the "race against time," needs for increased structuring of family life and of creative work and shifts from physical to intellectual play and from being a mentee to mentorship.

在一个研究所,48%的医师候选人在做课堂作业时都超过了40岁。这一比例在过去十年中有所增加,也许反映了新的经济限制和女性候选人比例的增加。回顾弗洛伊德的第一次培训分析,以及与一些当今候选人的对话表明,在职业生涯中期选择培训可以解决具体的成人发展问题,包括“与时间赛跑”,需要增加家庭生活和创造性工作的结构,从体力游戏转向智力游戏,从被指导者转向导师。
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引用次数: 0
Early transferences and transference-like reactions. 早期移情和移情样反应。
D S Werman

Some patients manifest intense transferences or transference-like reactions in the earliest hours of psychotherapy. Although these reactions may actually represent transference, they may also arise from other sources, such as aspects of a patient's character, displacements from former therapists, impaired reality testing, information about the therapist, and therapist's behavior. Clinical examples are presented, and their management is discussed.

有些病人在心理治疗的最初几个小时表现出强烈的移情或移情样反应。虽然这些反应实际上可能代表移情,但它们也可能来自其他来源,例如患者性格的各个方面,与前治疗师的位移,受损的现实测试,关于治疗师的信息,以及治疗师的行为。提出了临床实例,并对其处理进行了讨论。
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引用次数: 0
Babies of the earthquake: follow-up study of their first 15 months. 地震婴儿:前15个月的随访研究。
M I López, N A León

This report reviews the phenomenology related to the rescue and later development of the newborn babies buried in the rubble of several collapsed maternity hospitals in Mexico City during the earthquake of September 1985. We describe the rescue process as well as the impact of this process on the community. The rescued babies' development has been followed through the first 15 months of their lives and we describe our observations. We also review the implications of the emotional burdens that these babies may bear and the possible repercussions later in their development.

本报告回顾了1985年9月墨西哥城地震期间被埋在几家倒塌的妇产医院废墟中的新生婴儿的救援和后来的发育情况。我们描述了救援过程以及这一过程对社区的影响。这些获救的婴儿在他们生命的前15个月里一直在发育,我们描述了我们的观察结果。我们还回顾了这些婴儿可能承受的情感负担的含义以及他们在以后的发展中可能产生的影响。
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引用次数: 0
Limited clinical utility of urinary MHPG. 尿MHPG的临床应用有限。
A L Lieber

Ninety-five inpatient, RDC-diagnosed major depressives, 68 unipolar and 27 bipolar, underwent 72-hour urine collection for the measurement of 3-methoxy-4-hydroxyphenylglycol (MHPG). The average 24-hour urinary MHPG was compared by multivariate analysis of variance with the postdexamethasone cortisol (DST), the delta thyroid stimulating hormone (TRHST), six quantitative EEG (QEEG) measures of regional interhemispheric symmetry and six QEEG measures of focal frequency abnormalities. MHPG failed to discriminate between unipolar and bipolar II depression. It showed no significant correlations with postdexamethasone cortisol or delta TSH. It failed to correlate with QEEG regional coherence or with focal frequency abnormalities. MHPG covaries independently of other markers of depression.

95名住院患者,被诊断为重度抑郁症患者,68名单极患者,27名双相患者,接受72小时尿液收集,用于测量3-甲氧基-4-羟基苯基乙二醇(MHPG)。通过多变量方差分析比较24小时平均尿MHPG与地塞米松后皮质醇(DST)、甲状腺刺激激素(TRHST)、区域半球间对称的6项定量脑电图(QEEG)和局频异常的6项定量脑电图(QEEG)。MHPG不能区分单相和双相II型抑郁症。与地塞米松后皮质醇或TSH无显著相关性。它与QEEG区域相干性或焦频率异常不相关。MHPG的协变独立于抑郁症的其他标志物。
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引用次数: 0
Anomalous motoric lateralization and schizophrenia: clinical implications. 异常运动侧化与精神分裂症:临床意义。
P Hauser, C Hudson, J Hood, M Seeman

Sixty-five schizophrenic subjects (46 men and 19 women) were tested for motor preference and compared to age and sex-matched controls. There were significantly more nondextrals among the schizophrenic women. Both male and female nondextral schizophrenics were hospitalized more frequently and for longer periods than dextral schizophrenics.

65名精神分裂症患者(46名男性和19名女性)接受了运动偏好测试,并与年龄和性别匹配的对照组进行了比较。女性精神分裂症患者的非右旋活动明显增多。男性和女性非右旋精神分裂症患者比右旋精神分裂症患者住院更频繁,住院时间更长。
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引用次数: 0
Attachment, loss and rediscovery. 依恋,失去和重新发现。
G E Vaillant

This paper suggests that separation and loss in early childhood may be less critical to later life than some people believe. Rather, internalization--after as well as before, age five--may be a developmental process to which psychotherapists need to pay particular attention. By attending to our patient's experiences of separation and loss, we allow them a metaphor, a language, with which they can describe the vicissitudes of lasting attachments. Similarly, the separation/individuation process of infancy, popularized by Klein and Mahler, is important, not just because it describes the biosocial fact of preverbal infancy but because it draws our attention to a metaphor that describes the struggle for identity that characterizes young adulthood.

这篇论文表明,童年早期的分离和失去对以后的生活可能没有一些人认为的那么重要。更确切地说,内化——在五岁之后和五岁之前——可能是一个心理治疗师需要特别关注的发展过程。通过关注病人的分离和失去的经历,我们给他们提供了一种隐喻,一种语言,他们可以用这种语言来描述持久依恋的变迁。同样,Klein和Mahler推广的婴儿期分离/个性化过程也很重要,不仅因为它描述了言语前婴儿期的生物社会事实,还因为它把我们的注意力吸引到一个比喻上,这个比喻描述了青年成年期特征的身份斗争。
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引用次数: 0
Depression in vascular dementia. 血管性痴呆的抑郁。
J L Cummings

Vascular dementia results from ischemic injury to the brain. Depression is a frequent complication of cerebrovascular dementia (CVD) occurring in 25 to 80% of patients during the course of their illness. Depression is unrelated to the severity of intellectual compromise or to the co-existence of delusions. The symptom profile of depression in CVD is indistinguishable from that of late-onset idiopathic major depressive episodes. The frequency of depression differs with the subtype of CVD and is most common in disorders with lesions of the frontal lobes, either cortical or subcortical. In addition to lesion site, other contributors to depression in CVD include vascular disease of other organs, drug therapy of co-existing medical conditions, and psychological reactions to disability. The depression of CVD responds to treatment with antidepressant agents.

血管性痴呆是由脑缺血性损伤引起的。抑郁症是脑血管性痴呆(CVD)的常见并发症,25%至80%的患者在病程中出现抑郁症。抑郁症与智力妥协的严重程度或妄想的共存无关。CVD患者的抑郁症状与迟发性特发性重性抑郁发作的症状难以区分。抑郁的频率随CVD亚型的不同而不同,在额叶(皮质或皮质下)病变的疾病中最常见。除病变部位外,CVD患者抑郁的其他因素还包括其他器官的血管疾病、共存疾病的药物治疗以及对残疾的心理反应。心血管疾病患者的抑郁对抗抑郁药物治疗有反应。
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引用次数: 0
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The Hillside journal of clinical psychiatry
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