{"title":"[Differential leukocyte count].","authors":"M. D. DE GROODT","doi":"10.32388/bcp669","DOIUrl":"https://doi.org/10.32388/bcp669","url":null,"abstract":"","PeriodicalId":78103,"journal":{"name":"Belgisch tijdschrift voor geneeskunde","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80985207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-08-30DOI: 10.5772/INTECHOPEN.69362
J. Baerg, Arul S. Thirumoorthi, Rajaie Hazboun
Despite advances in neonatal and surgical care, the management of congenital diaphrag‐ matic hernia (CDH) remains challenging with no definitive standard treatment guide‐ lines. Several centers report mortality rates as low as 20%, but if extracorporeal membrane oxygenation (ECMO) support is required, the mortality rate rises to 50%. The disease severity is related to the degree of pulmonary hypoplasia and pulmonary hypertension that occurs with CDH. Both conditions decrease the infant’s ability to ventilate and oxy‐ genate adequately at delivery. These physiologic conditions that impair gas exchange are the important determinants of morbidity and mortality in CDH infants. Presently, delivery of infants with CDH is recommended close to term gestation. The focus of care includes gentle ventilation, hemodynamic monitoring, and treatment of pulmonary hypertension followed by surgery for the defect. Extracorporeal membrane oxygenation (ECMO) is considered after failure of conventional medical management for infants ≥ 34 weeks’ gestation or with weight >2 kg and no associated major lethal anomalies. This chapter discusses long‐term follow‐up recommendations for survivors, which should involve a multidisciplinary approach, as there are many surgical and nonsurgical conse‐ quences to the disease process. Clinical strategies that address these multifaceted aspects of care, from prenatal to long‐term follow‐up, may further reduce the high mortality rate for these infants.
{"title":"Congenital diaphragmatic hernia","authors":"J. Baerg, Arul S. Thirumoorthi, Rajaie Hazboun","doi":"10.5772/INTECHOPEN.69362","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.69362","url":null,"abstract":"Despite advances in neonatal and surgical care, the management of congenital diaphrag‐ matic hernia (CDH) remains challenging with no definitive standard treatment guide‐ lines. Several centers report mortality rates as low as 20%, but if extracorporeal membrane oxygenation (ECMO) support is required, the mortality rate rises to 50%. The disease severity is related to the degree of pulmonary hypoplasia and pulmonary hypertension that occurs with CDH. Both conditions decrease the infant’s ability to ventilate and oxy‐ genate adequately at delivery. These physiologic conditions that impair gas exchange are the important determinants of morbidity and mortality in CDH infants. Presently, delivery of infants with CDH is recommended close to term gestation. The focus of care includes gentle ventilation, hemodynamic monitoring, and treatment of pulmonary hypertension followed by surgery for the defect. Extracorporeal membrane oxygenation (ECMO) is considered after failure of conventional medical management for infants ≥ 34 weeks’ gestation or with weight >2 kg and no associated major lethal anomalies. This chapter discusses long‐term follow‐up recommendations for survivors, which should involve a multidisciplinary approach, as there are many surgical and nonsurgical conse‐ quences to the disease process. Clinical strategies that address these multifaceted aspects of care, from prenatal to long‐term follow‐up, may further reduce the high mortality rate for these infants.","PeriodicalId":78103,"journal":{"name":"Belgisch tijdschrift voor geneeskunde","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84349655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Problems in the commercial airplane transport of patients with cardiopulmonary disease].","authors":"P Vermeire","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78103,"journal":{"name":"Belgisch tijdschrift voor geneeskunde","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16921345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of aplastic anemia].","authors":"W van Hove","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78103,"journal":{"name":"Belgisch tijdschrift voor geneeskunde","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16921337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Indications and contra-indications for oxygen therapy and respiratory analeptics].","authors":"J Tasson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78103,"journal":{"name":"Belgisch tijdschrift voor geneeskunde","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15483037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of rheumatoid arthritis].","authors":"A Vermeulen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":78103,"journal":{"name":"Belgisch tijdschrift voor geneeskunde","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1965-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"16921333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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