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[Staged hybrid treatment of a patient with descending thoracic and abdominal aortic aneurysm (case report)]. 【分阶段混合治疗胸腹降主动脉瘤1例(附1例报告)】。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-46-52
L N Ivanov, A S Mukhin, R Yu Nagaev, S V Naumov, V A Pugin, M V Kozina, E V Yurasova

Here we describe a clinical case of successful staged treatment of descending thoracic and abdominal aorta aneurysmal lesions with unchanged segment of the visceral portion between them. An anatomical peculiarity of the abdominal aortic aneurysm was the presence of angulation and an aneurysmal lesion of the left iliac artery, thus requiring the use of a hybrid strategy. The patient had a high surgical risk associated with comorbidity. At the first stage, he underwent aortofemoral prosthetic repair and 3 months thereafter received an endograft implanted into the descending thoracic aorta with the positioning of the distal portion of the stent graft at the level of the XI thoracic vertebra. Previous aortofemoral prosthetic repair was an independent risk factor for spinal complications avoided by optimal perioperative and postoperative patient management. The control studies showed an adequate position of the stent graft, patency of the aortofemoral prosthesis, and no dilatation of the visceral portion of the aorta.

在此,我们描述了一个成功的分阶段治疗胸降主动脉和腹主动脉动脉瘤病变,它们之间的内脏部分不变。腹主动脉瘤的解剖特点是存在成角和左髂动脉的动脉瘤病变,因此需要使用混合策略。患者手术风险高,伴有合并症。第一阶段,患者行主动脉股动脉假体修复术,3个月后接受置入胸降主动脉内移植物,支架远端定位于第XI胸椎水平。通过优化围手术期和术后患者管理,先前的股骨主动脉假体修复是脊柱并发症的独立危险因素。对照研究显示支架位置合适,主动脉股假体通畅,主动脉内脏部分无扩张。
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引用次数: 0
[Operative access to the left radial artery on the back of the hand for X-ray endovascular surgical interventions]. [手术进入手背左桡动脉进行x线血管内手术干预]。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-109-118
B I Milenkin, E N Prazdnikov, G A Baranov
<p><strong>Objective: </strong>The study was aimed at improving the technique and results of X-ray endovascular surgical interventions by investigation of the anatomical and clinical aspects of surgical access to the left radial artery on the back of the hand.</p><p><strong>Patients and methods: </strong>From 2019 to 2021, we operated on a total of 210 patients randomly assigned to undergo X-ray endovascular surgical interventions through distal approaches from the radial artery on the back of the left hand or in the lower third of the right forearm. The distal approach to the radial artery of the back of the left hand was successful in 100 of 104 patients, and the conventional radial approach in the lower third of the right forearm in 100 of 106 patients. All patients underwent anthropometric measurements and Doppler ultrasonography in the zone of the arterial access. We evaluated the potential efficacy and feasibility of accesses for the intervention, the frequency of access conversion, early (hemorrhagic) and late local postoperative complications (occlusion of the radial artery) associated with a specific type of the arterial access. Subjective pain perception was evaluated using a visual analog scale during both the vascular access and hemostatic bandage application.</p><p><strong>Results: </strong>Distal radial access on the back of the left hand was effectively performed in 96.2% of cases, and conventional radial access on the inner surface of the lower third of the right forearm in 94.3% of cases. The analysis of X-ray endovascular surgical interventions was performed in 100 patients with successful puncture of the radial artery on the back of the left hand (Group 1) and in 100 patients with successful conventional puncture of the radial artery on the internal surface of the lower third of the right forearm (Group 2). The mean age was 68.4±11.9 and 65.2±11.2 years in Group 1 and Group 2 patients, respectively (p<0.05). There were no statistically significant between-group differences in gender or anthropometric parameters (p<0.005). In male patients, the internal diameter of the radial artery on the inner surface of the lower third of the forearm (2.36±0.09 mm) and on the back surface of the hand (1.83±0.1 mm) was significantly larger (p<0.0001) compared with women (2.14±0.11 mm and 1.70±0.09 mm, respectively). In men, the average wrist circumference was 17.98 cm, and in women - 16.20 cm. The correlation analysis identified a statistically significant association of both the internal diameter of the radial artery on the inner surface of the lower third of the forearm (p<0.0001) and the diameter of the vessel on the back of the hand (p<0.0001) with the results of measuring the circumference of the wrist. There was no statistically significant relationship between the diameter of the artery on the inner surface of the lower third of the forearm (p=0.4118) and on the back surface of the hand (p=0.2242) with the body mass index. In Group 1 pa
目的:通过对手背左桡动脉手术通路的解剖和临床研究,提高x线血管内介入手术的技术和效果。患者和方法:2019年至2021年,我们随机选取210例患者进行手术,从左手背部桡动脉远端入路或右前臂下三分之一行x线血管内手术干预。104例患者中有100例采用远端桡动脉入路手术成功,106例患者中有100例采用常规桡动脉入路手术成功。所有患者都在动脉通道区域进行了人体测量和多普勒超声检查。我们评估了通道干预的潜在疗效和可行性,通道转换的频率,与特定类型动脉通路相关的早期(出血)和晚期局部术后并发症(桡动脉闭塞)。在血管通路和止血绷带应用期间,使用视觉模拟量表评估主观疼痛感觉。结果:左手后侧桡骨远端入路有效率为96.2%,右前臂下三分之一内表面常规桡骨入路有效率为94.3%。对100例成功穿刺左手手背桡动脉的患者(1组)和100例成功穿刺右前臂下三分之一内表面桡动脉的患者(2组)进行x线血管内手术干预分析。1组患者平均年龄为68.4±11.9岁,2组患者平均年龄为65.2±11.2岁(p0.05)。结论:手术进入手背左桡动脉进行x线血管内手术干预可以而且应该在临床实践中得到更广泛的应用。这种通路可以被认为是传统的前臂下三分之一桡动脉穿刺的合理选择。
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引用次数: 0
3615 consecutive carotid endarterectomies without intraluminal shunt. 3615例连续颈动脉内膜切除术,未行腔内分流术。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-78-84
A N Vachev, N I Chernysheva, O V Dmitriev, M Yu Stepanov, E A Golovin, M G Prozhoga, O V Tereshina, P O Kuznetsov

Background: Carotid endarterectomy is one of the most frequently performed peripheral vascular operations. We present herein a retrospective and prospective analysis of carotid endarterectomy performed without an intraluminal arterial shunt in a total of 3615 patients.

Objective: The purpose of this study was to assess efficacy and safety of the technology of perioperative management and the technique of carotid endarterectomy with no intraluminal arterial shunt.

Patients and methods: Our study included 3615 patients successively operated on at the same department. All patients underwent elective carotid endarterectomy without an intraluminal arterial shunt. The stages of perioperative management were standardized. All operations were performed under combined general anesthesia. Prior to clamping carotid arteries, we elevated the level of arterial pressure (AP) by 20-30% above the 'working' level. Adequacy of blood supply of the brain was controlled by means of cerebral oximetry using the Somanetics INVOS 3100 unit and by the assessment of retrograde blood flow through the internal carotid artery. 3145 (87%) patients underwent modified carotid endarterectomy with creation of high divarication. 470 (13%) patients were subjected to classical carotid endarterectomy with autovenous plasty of the internal and common carotid arteries. The criteria for making the diagnosis of ischemic stroke with determination of the mechanism of its development were standardized.

Results: 3566 (98.64%) patients had no evidence of perioperative stroke and 49 (1.36%) patients developed intraoperative stroke. In 41 (1.13%) of the 3615 patients, the mechanism of development of intraoperative ischemic stroke was atheroembolic, in five (0.14%) - hemodynamic, and in three (0.08%) - lacunar. Eleven (0.3%) patients died from ischemic stroke.

Conclusion: Carotid endarterectomy without an intraluminal shunt did not increase the risk of developing ischemic stroke. Correction of cerebral hypoperfusion during carotid artery cross-clamping should be recognized as an anesthesiological task.

背景:颈动脉内膜切除术是最常用的外周血管手术之一。我们在此提出了一项回顾性和前瞻性分析,在没有腔内动脉分流术的情况下,共3615例患者进行了颈动脉内膜切除术。目的:评价围手术期处理技术和颈动脉内膜切除术无腔内动脉分流术技术的有效性和安全性。患者和方法:我们的研究包括3615例在同一科室先后手术的患者。所有患者均行选择性颈动脉内膜切除术,未行腔内动脉分流术。规范围手术期管理分期。所有手术均在综合全身麻醉下进行。在钳住颈动脉之前,我们将动脉压(AP)水平提高20-30%,高于“工作”水平。通过使用Somanetics INVOS 3100装置的脑血氧仪和通过颈内动脉逆行血流的评估来控制脑血供的充分性。3145例(87%)患者行改良颈动脉内膜切除术,形成高度分流。470例(13%)患者接受颈内动脉和颈总动脉自体静脉成形术的颈动脉内膜切除术。规范了缺血性脑卒中的诊断标准及发病机制的确定。结果:3566例(98.64%)患者无围术期卒中迹象,49例(1.36%)患者出现术中卒中。在3615例患者中,41例(1.13%)患者术中缺血性卒中的发生机制为动脉粥样硬化栓塞性,5例(0.14%)为血流动力学,3例(0.08%)为腔隙性。11例(0.3%)患者死于缺血性中风。结论:颈动脉内膜切除术不加腔内分流术不会增加发生缺血性脑卒中的风险。颈动脉交叉夹持术中脑灌注不足的纠正应被视为一项麻醉任务。
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引用次数: 0
[Cyanoacrylate adhesive closure of varicose veins in a woman with juvenile epilepsy and restless leg syndrome (case report)]. [氰基丙烯酸酯胶粘剂治疗青少年癫痫伴不宁腿综合征女性静脉曲张1例(附1例报告)]。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-59-63
O Shirinbek, G V Mnatsakanyan, S N Odinokova, E Yu Baeva

Presented herein is a clinical case report concerning successful use of cyanoacrylate glue obliteration in a female patient with lower limb varicose veins, restless leg syndrome, and a long history of epilepsy. The intervention was performed under local anesthesia. Positive results were achieved regarding varicose disease symptoms, with a decrease in the frequency and intensity of epileptic seizures. It is noted that a multidisciplinary approach is an important condition for achieving success in treatment of such patients and improving their quality of life.

本文报告一例成功应用氰基丙烯酸酯胶闭塞治疗下肢静脉曲张、不宁腿综合征和长期癫痫史的女性患者。干预在局部麻醉下进行。在静脉曲张疾病症状方面取得了积极的成果,癫痫发作的频率和强度都有所下降。值得注意的是,多学科方法是成功治疗此类患者并改善其生活质量的重要条件。
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引用次数: 0
[New coronavirus infection as a provoking factor for the clinical manifestation of Bland-White-Garland syndrome (case report)]. 【新型冠状病毒感染作为白花环综合征临床表现的诱发因素(病例报告)】。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-64-69
S A Chepurnenko, M Y Kostrykin, V L Kostenko, D K Lobachev, A V Safonova

Background: A congenital malformation in the form of an abnormal origin of the left coronary artery from the pulmonary artery leads to the phenomenon of stealing the coronary arteries with a shunt from left to right, causing aberrant left ventricular perfusion. 9 out of 10 children die before reaching the age of one without surgery due to cardiac ischemia, infarction, or congestive heart failure secondary to mitral regurgitation. Some of them survive to a later age thanks to an adequate collateral blood supply through the entrapment of the right coronary artery.

Material and methods: The article presents a rare case of Bland-White-Garland syndrome manifestation in a woman aged 43 years.

Results: The angina clinic developed after a coronavirus infection, and was provoked by a constant tachycardia at rest of 90-100 beats per minute, aggravated by exercise. ECG Holter monitoring revealed episodes of severe ST-T depression. On the electrocardiogram - signs of focal cicatricial changes in the anterior septal and high lateral myocardium. Echocardioscopy established that the left coronary artery does not originate from the aorta, but from the pulmonary artery. Detection of a zone of reduced contractility of the myocardium of the left ventricle. A decrease in systolic function of the left ventricle was found (ejection fraction 48-50%). Spiral computed tomographic coronary angiography also confirmed the presence of this anomaly, an increase in the diameter of the left coronary artery up to 5 mm. The diameter of the right coronary artery was also increased to 8 mm. Multiple tortuous collaterals between the left and right coronary systems were revealed. Invasive coronary angiography confirmed the presence of this anomaly. An operation was performed: an anastomosis was made between the aorta and the left coronary artery in an end-to-side manner. The trunk of the pulmonary artery was reconstructed with a xenopericardial patch.

Conclusion: In the presented case, it was possible to demonstrate a late manifestation of the Bland-White-Garland syndrome at the age of 43 years. Reconstruction of the coronary bed significantly improved the patient's condition and her quality of life.

背景:一种先天性畸形,表现为左冠状动脉起源于肺动脉的异常,导致冠状动脉从左向右分流,导致左心室灌注异常。由于心脏缺血、梗塞或二尖瓣返流引起的充血性心力衰竭,10个儿童中有9个在1岁前死亡,而没有手术。由于右冠状动脉堵塞,有足够的侧支血液供应,他们中的一些人活到了晚年。材料与方法:本文报告一例43岁女性罕见的白-白-花环综合征。结果:心绞痛临床发生于冠状病毒感染后,静息时持续心动过速90-100次/分,运动加重心绞痛。心电图动态心电图监测显示有严重ST-T抑郁发作。心电图-前间隔和高外侧心肌局灶性瘢痕改变的征象。超声心动图证实左冠状动脉不是起源于主动脉,而是起源于肺动脉。左心室心肌收缩性减弱区域的检测。左心室收缩功能下降(射血分数48-50%)。螺旋ct冠状动脉造影也证实了这种异常的存在,左冠状动脉直径增加了5毫米。右冠状动脉直径增大至8mm。显示左右冠状动脉系统之间有多条曲折的侧支。有创冠状动脉造影证实了这种异常的存在。手术:将主动脉与左冠状动脉端侧吻合。用异种心包补片重建肺动脉干。结论:在本病例中,有可能在43岁时表现出Bland-White-Garland综合征的晚期表现。冠状动脉床的重建显著改善了患者的病情和生活质量。
{"title":"[New coronavirus infection as a provoking factor for the clinical manifestation of Bland-White-Garland syndrome (case report)].","authors":"S A Chepurnenko, M Y Kostrykin, V L Kostenko, D K Lobachev, A V Safonova","doi":"10.33029/1027-6661-2023-29-3-64-69","DOIUrl":"https://doi.org/10.33029/1027-6661-2023-29-3-64-69","url":null,"abstract":"<p><strong>Background: </strong>A congenital malformation in the form of an abnormal origin of the left coronary artery from the pulmonary artery leads to the phenomenon of stealing the coronary arteries with a shunt from left to right, causing aberrant left ventricular perfusion. 9 out of 10 children die before reaching the age of one without surgery due to cardiac ischemia, infarction, or congestive heart failure secondary to mitral regurgitation. Some of them survive to a later age thanks to an adequate collateral blood supply through the entrapment of the right coronary artery.</p><p><strong>Material and methods: </strong>The article presents a rare case of Bland-White-Garland syndrome manifestation in a woman aged 43 years.</p><p><strong>Results: </strong>The angina clinic developed after a coronavirus infection, and was provoked by a constant tachycardia at rest of 90-100 beats per minute, aggravated by exercise. ECG Holter monitoring revealed episodes of severe ST-T depression. On the electrocardiogram - signs of focal cicatricial changes in the anterior septal and high lateral myocardium. Echocardioscopy established that the left coronary artery does not originate from the aorta, but from the pulmonary artery. Detection of a zone of reduced contractility of the myocardium of the left ventricle. A decrease in systolic function of the left ventricle was found (ejection fraction 48-50%). Spiral computed tomographic coronary angiography also confirmed the presence of this anomaly, an increase in the diameter of the left coronary artery up to 5 mm. The diameter of the right coronary artery was also increased to 8 mm. Multiple tortuous collaterals between the left and right coronary systems were revealed. Invasive coronary angiography confirmed the presence of this anomaly. An operation was performed: an anastomosis was made between the aorta and the left coronary artery in an end-to-side manner. The trunk of the pulmonary artery was reconstructed with a xenopericardial patch.</p><p><strong>Conclusion: </strong>In the presented case, it was possible to demonstrate a late manifestation of the Bland-White-Garland syndrome at the age of 43 years. Reconstruction of the coronary bed significantly improved the patient's condition and her quality of life.</p>","PeriodicalId":7821,"journal":{"name":"Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery","volume":"29 3","pages":"64-69"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Eversion endarterstentectomy for treatment critical in-stent restenosis after Wallstent carotid stenting]. [外翻动脉内膜切除术治疗颈动脉支架植入术后支架内再狭窄]。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-119-128
A S Kutovaya, A L Golovyuk, A V Chupin

Acute stroke is the second cause of death in Russia. Currently, carotid endarterectomy remains the 'gold standard' for stroke prevention in patients with stenosis of the internal carotid arteries. Endovascular treatment of atherosclerotic lesion of the carotid bifurcation claims to be an alternative to open reconstructions. The problem of restenosis after both types of intervention remains a significant problem at the moment. According to the literature, massive calcification of an atherosclerotic plaque is a predictor of a greater number of complications during stenting and the impossibility of achieving technical success due to residual stenosis and stent deformation in the long-term period. We summarized the literature data regarding the results of stenting in patients with calcified plaques, risk factors for restenosis, and analyzed the published results of open surgical interventions for in-stent restenosis after endovascular procedures. We also present our own clinical case of sequential bilateral eversion carotid endarterstenectomy in a patient with critical in-stent restenosis of the internal carotid arteries after Wallstent stent implantation.

急性中风是俄罗斯第二大死因。目前,颈动脉内膜切除术仍然是预防颈内动脉狭窄患者中风的“金标准”。血管内治疗的动脉粥样硬化病变的颈动脉分叉声称是一个替代开放重建。目前,两种干预后的再狭窄问题仍然是一个重要的问题。根据文献,动脉粥样硬化斑块的大量钙化预示着支架植入过程中更多的并发症,并且由于长期的残留狭窄和支架变形而不可能获得技术成功。我们总结了钙化斑块患者支架置入结果、再狭窄危险因素的文献资料,并分析了血管内手术后支架内再狭窄开放手术干预的已发表结果。我们也提出了我们自己的临床病例,顺序双侧外翻颈动脉内膜切除术的患者内颈动脉支架植入术后支架内再狭窄的严重。
{"title":"[Eversion endarterstentectomy for treatment critical in-stent restenosis after Wallstent carotid stenting].","authors":"A S Kutovaya, A L Golovyuk, A V Chupin","doi":"10.33029/1027-6661-2023-29-3-119-128","DOIUrl":"https://doi.org/10.33029/1027-6661-2023-29-3-119-128","url":null,"abstract":"<p><p>Acute stroke is the second cause of death in Russia. Currently, carotid endarterectomy remains the 'gold standard' for stroke prevention in patients with stenosis of the internal carotid arteries. Endovascular treatment of atherosclerotic lesion of the carotid bifurcation claims to be an alternative to open reconstructions. The problem of restenosis after both types of intervention remains a significant problem at the moment. According to the literature, massive calcification of an atherosclerotic plaque is a predictor of a greater number of complications during stenting and the impossibility of achieving technical success due to residual stenosis and stent deformation in the long-term period. We summarized the literature data regarding the results of stenting in patients with calcified plaques, risk factors for restenosis, and analyzed the published results of open surgical interventions for in-stent restenosis after endovascular procedures. We also present our own clinical case of sequential bilateral eversion carotid endarterstenectomy in a patient with critical in-stent restenosis of the internal carotid arteries after Wallstent stent implantation.</p>","PeriodicalId":7821,"journal":{"name":"Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery","volume":"29 3","pages":"119-128"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Contemporary strategies to the level of distal anastomosis formation for patients with acute DeBakey type I aortic dissection (literature review and own view on the problem)]. 【急性DeBakey I型主动脉夹层远端吻合口形成水平的当代策略(文献回顾及个人观点)】。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-140-147
V S Selyaev, A V Redkoborody

The article presents the data of domestic and foreign literature on the surgical treatment of DeBakey type I acute aortic dissection, as one of the most challenging pathologies in the practice of a cardiac surgeon. Unfavorable nature of the disease, a variation in presentation and clinical course along with an urgent treatment require significant attentiveness. A unified concept of treatment is practically excluded due to the variety of surgical approaches, clinical experience and interventions. There have been demonstrated approaches to surgical treatment and level of a distal anastomosis formation including simple clamp on operations only on the ascending aorta to total arch replacement with hybrid-techniques and their combination in the form of proximalization of the distal anastomosis zone. The clinic's own vision of this problem is also presented.

DeBakey I型急性主动脉夹层是心脏外科实践中最具挑战性的疾病之一,本文介绍了DeBakey I型急性主动脉夹层的手术治疗的国内外文献资料。疾病的不利性质,在表现和临床过程的变化以及紧急治疗需要显著的关注。由于手术入路、临床经验和干预措施的多样性,实际上排除了统一的治疗概念。已经证明了手术治疗和远端吻合形成水平的方法,包括仅在升主动脉上进行简单的钳夹手术,以混合技术进行全弓置换,并以远端吻合区近端化的形式将它们结合起来。本文还介绍了诊所对这一问题的看法。
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引用次数: 0
[Catheter-guided thrombolysis for acute lower-limb ischemia]. [导管引导溶栓治疗急性下肢缺血]。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-31-37
S A Papoyan, A A Shegolev, E S Chizhova, K S Asaturyan, D D Syromyatnikov, D G Gromov

Regional thrombolytic therapy for acute ischemia of lower extremities is one of therapeutic methods, which in some cases is a method of choice, especially when open reconstructive surgical intervention is associated with a high risk of complications. Besides, thrombolytic therapy can be considered as the first stage of treatment, as well as a method of choice to restore patency of the arterial distal bed.

局部溶栓治疗是急性下肢缺血的治疗方法之一,在某些情况下是一种选择方法,特别是当开放重建手术干预与并发症的高风险相关时。此外,溶栓治疗可作为治疗的第一阶段,也是恢复远端动脉通畅的首选方法。
{"title":"[Catheter-guided thrombolysis for acute lower-limb ischemia].","authors":"S A Papoyan, A A Shegolev, E S Chizhova, K S Asaturyan, D D Syromyatnikov, D G Gromov","doi":"10.33029/1027-6661-2023-29-3-31-37","DOIUrl":"https://doi.org/10.33029/1027-6661-2023-29-3-31-37","url":null,"abstract":"<p><p>Regional thrombolytic therapy for acute ischemia of lower extremities is one of therapeutic methods, which in some cases is a method of choice, especially when open reconstructive surgical intervention is associated with a high risk of complications. Besides, thrombolytic therapy can be considered as the first stage of treatment, as well as a method of choice to restore patency of the arterial distal bed.</p>","PeriodicalId":7821,"journal":{"name":"Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery","volume":"29 3","pages":"31-37"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hybrid treatment of a patient with a thoracic aortic aneurysm and lung cancer (case report)]. [1例胸主动脉瘤合并肺癌患者的混合治疗(附病例报告)]。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-53-58
S A Papoyan, M D Ter-Ovanesov, A A Shchegolev, N R Chernaya, D S Amirkhanyan

In this article, we present a clinical case of staged treatment of a patient with lung cancer and a thoracic aortic aneurysm. At the first stage, the patient underwent an extended upper lobectomy on the right with resection of the apical segment of the lower lobe of the lung and mediastinal lymph node dissection. At the second stage, a hybrid operation was performed, including partial debranching of the aortic arch and endovascular thoracic aortic aneurysm repair. The chosen approach made it possible to reduce the overall traumaticity of surgical interventions, while maintaining the radical nature of treatment. This clinical example is an illustration of the fact that the modern hybrid strategy for the treatment of thoracic aortic pathology (in particular, the aortic arch) significantly expands the possibilities of treating patients with combined pathology, allowing to reduce the risks of both general surgical complications and cerebral circulation impairments. However, the place of this approach can only be determined after assessing the long-term results, in particular the risks and frequency of aortic remodeling.

在这篇文章中,我们提出一个临床病例分期治疗患者肺癌和胸主动脉瘤。在第一阶段,患者在右侧进行了扩大上肺叶切除术,切除了肺下肺叶的根尖段,并进行了纵隔淋巴结清扫。在第二阶段,进行混合手术,包括主动脉弓部分去分支和血管内胸主动脉瘤修复。所选择的方法可以减少手术干预的整体创伤,同时保持治疗的根治性。这个临床例子说明了这样一个事实,即现代混合策略治疗胸主动脉病理(特别是主动脉弓)显著扩大了治疗合并病理患者的可能性,从而降低了一般手术并发症和脑循环损伤的风险。然而,这种方法的位置只能在评估长期结果后才能确定,特别是主动脉重塑的风险和频率。
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引用次数: 0
[Evaluation of embologenicity in endovascular treatment of peripheral arteries using drug-coated balloons: interim results]. [药物包被球囊血管内治疗外周动脉的栓塞性评价:中期结果]。
Q3 Medicine Pub Date : 2023-10-06 DOI: 10.33029/1027-6661-2023-29-3-99-108
A A Gostev, O S Osipova, A S Klinkova, O V Kamenskaya, A A Karpenko
<p><strong>Background: </strong>The number of endovascular interventions on the arteries of the lower extremities is increasing every year. To improve the long-term results of stenting, many different options are proposed (the use of biomimetic devices with increased flexibility or the use of drug coating with cytostatics to reduce neointimal hyperplasia). However, a recent meta-analysis of randomized trials examining the long-term risk of major amputation with paclitaxel-coated balloons in peripheral arterial disease (3760 people) showed that there is an increased risk of major amputation following the use of paclitaxel-coated balloons in peripheral arteries (HR 1.66 (95% CI 1.14-2.42; p=0.008, one-stage stratified Cox model). This may be due to distal embolism of drug coating elements, resulting in poor peripheral blood flow to the extremity. Additional randomized prospective studies are needed to identify or refute the fact of intraoperative distal embolism when using drug-coated balloons. Purpose - еvaluate the efficacy and safety of using drug-coated balloons up to 12 months after treatment.</p><p><strong>Material and methods: </strong>A prospective, randomized, single-center study. 20 patients with peripheral arteries disease with above the knee atherosclerotic lesions with symptomatic chronic limb ischemia (Rutherford categories 3-6) were randomized into two groups (10 people, respectively). The first group of patients underwent percutaneous transluminal angioplasty using a drug-coated balloon, the second group - using a conventional balloon. Before surgery, after 2 days and after 6 months of observation, transcutaneous oximetry (ТсрО2, mm Hg) and laser doppler flowmetry (perfusion units - perf. units) were used to study microcirculatory blood flow of the lower extremities, as well as duplex scanning of arteries and examination by a vascular surgeon with the definition of quality of life, using the SF-36 questionnaire. Intraoperatively were provided emboli-detection.</p><p><strong>Results: </strong>The groups were comparable in terms of baseline clinical and anthropometric characteristics. The procedural success was 100% in all patients. Intraoperative emboli-detection showed the fact of distal embolism in 10 (100%) patients in the drug-coated balloon group (median number of emboli = 200) and in 8 (80%) patients in the conventional balloon group (median number of emboli = 135) without statistically significant differences (p=0.47). In the early and late postoperative periods (6 months of follow-up), there were no cases of thrombosis, amputations, significant cardiovascular events (myocardial infarction, stroke), deaths, or any complications associated with endovascular access (hematomas, infection, neuropathy). Primary patency in the drug-coated balloon group was 100%, in the conventional balloon group 70% (2 cases of hemodynamically significant restenosis and 1 case of occlusion of the operated segment), plog-rank=0.06. Evaluation of the
这些变化可以解释为在使用适当的器械时,药物涂层元件的微栓塞现象和远端微血管的暂时阻塞。值得注意的是,两组在术后早期和后期的疗效和安全性方面具有可比性。
{"title":"[Evaluation of embologenicity in endovascular treatment of peripheral arteries using drug-coated balloons: interim results].","authors":"A A Gostev, O S Osipova, A S Klinkova, O V Kamenskaya, A A Karpenko","doi":"10.33029/1027-6661-2023-29-3-99-108","DOIUrl":"https://doi.org/10.33029/1027-6661-2023-29-3-99-108","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The number of endovascular interventions on the arteries of the lower extremities is increasing every year. To improve the long-term results of stenting, many different options are proposed (the use of biomimetic devices with increased flexibility or the use of drug coating with cytostatics to reduce neointimal hyperplasia). However, a recent meta-analysis of randomized trials examining the long-term risk of major amputation with paclitaxel-coated balloons in peripheral arterial disease (3760 people) showed that there is an increased risk of major amputation following the use of paclitaxel-coated balloons in peripheral arteries (HR 1.66 (95% CI 1.14-2.42; p=0.008, one-stage stratified Cox model). This may be due to distal embolism of drug coating elements, resulting in poor peripheral blood flow to the extremity. Additional randomized prospective studies are needed to identify or refute the fact of intraoperative distal embolism when using drug-coated balloons. Purpose - еvaluate the efficacy and safety of using drug-coated balloons up to 12 months after treatment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Material and methods: &lt;/strong&gt;A prospective, randomized, single-center study. 20 patients with peripheral arteries disease with above the knee atherosclerotic lesions with symptomatic chronic limb ischemia (Rutherford categories 3-6) were randomized into two groups (10 people, respectively). The first group of patients underwent percutaneous transluminal angioplasty using a drug-coated balloon, the second group - using a conventional balloon. Before surgery, after 2 days and after 6 months of observation, transcutaneous oximetry (ТсрО2, mm Hg) and laser doppler flowmetry (perfusion units - perf. units) were used to study microcirculatory blood flow of the lower extremities, as well as duplex scanning of arteries and examination by a vascular surgeon with the definition of quality of life, using the SF-36 questionnaire. Intraoperatively were provided emboli-detection.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The groups were comparable in terms of baseline clinical and anthropometric characteristics. The procedural success was 100% in all patients. Intraoperative emboli-detection showed the fact of distal embolism in 10 (100%) patients in the drug-coated balloon group (median number of emboli = 200) and in 8 (80%) patients in the conventional balloon group (median number of emboli = 135) without statistically significant differences (p=0.47). In the early and late postoperative periods (6 months of follow-up), there were no cases of thrombosis, amputations, significant cardiovascular events (myocardial infarction, stroke), deaths, or any complications associated with endovascular access (hematomas, infection, neuropathy). Primary patency in the drug-coated balloon group was 100%, in the conventional balloon group 70% (2 cases of hemodynamically significant restenosis and 1 case of occlusion of the operated segment), plog-rank=0.06. Evaluation of the ","PeriodicalId":7821,"journal":{"name":"Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery","volume":"29 3","pages":"99-108"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery
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