Background: Intraperitoneal irrigation with a low-volume, high-concentration local anaesthetic in laparoscopic cholecystectomy (LC) provides less pain relief. We investigated the impact of high-volume, low-concentration bupivacaine on postoperative pain and opioid requirement. Methods: Patients undergoing LC were randomised into Group B (20 mL of 0.5% bupivacaine in 480 mL normal saline) or Group S (500 mL of normal saline). Fifteen patients were included in both the groups but one patient was excluded from Group S because of bile duct injury. The primary outcome was Duration of Analgesia (DOA). The secondary outcomes were the Numeric Pain Rating Scale (NRS) at extubation, at 15 min, 30 min and 1, 2, 4, 8, 12 and 24 h. Cumulative rescue analgesics, incidence of postoperative nausea, vomiting and shoulder pain. Results: Mean (median/range) duration of analgesia was 6.45 ± 5.57 h (6/0.15-24) in Group B vs 3.18 ± 4.21 h (0.3/0.15-12) in Group S. Cumulative requirement of rescue analgesic was higher in saline group being 56.25 ± 33.92 mg for diclofenac and 83.57 ± 66.75 mg for tramadol vis-à-vis 40.9 ± 39.17 mg and 30.00 ± 52.78 mg, respectively, in bupivacaine group. Conclusion: Irrigation of the peritoneal cavity with high-volume low-concentration bupivacaine in LC increases the duration of analgesia and decreases the analgesic requirement in the postoperative period. Trial Registration: ClinicalTrials.gov identifier: CTRI/2019/02/017802 dated 25/02/2019.
背景:在腹腔镜胆囊切除术(LC)中使用低容量、高浓度的局麻药进行腹腔内灌注,镇痛效果较差。我们研究了高容量、低浓度布比卡因对术后疼痛和阿片类药物需求的影响。方法:接受 LC 的患者被随机分为 B 组(20 mL 0.5% 布比卡因与 480 mL 生理盐水混合)或 S 组(500 mL 生理盐水)。两组均有 15 名患者,但 S 组有一名患者因胆管损伤而被排除在外。主要结果是镇痛持续时间(DOA)。次要结果是拔管时、15 分钟、30 分钟、1、2、4、8、12 和 24 小时的数字疼痛评分量表(NRS)。结果:B 组的平均镇痛持续时间(中位数/范围)为 6.45 ± 5.57 小时(6/0.15-24),而 S 组为 3.18 ± 4.21 小时(0.3/0.15-12);生理盐水组的累计镇痛药需求量更高,双氯芬酸为 56.25 ± 33.92 毫克,曲马多为 83.57 ± 66.75 毫克,而布比卡因组分别为 40.9 ± 39.17 毫克和 30.00 ± 52.78 毫克。结论在LC中使用高容量低浓度布比卡因冲洗腹腔可延长镇痛时间,减少术后镇痛剂的需求量。试验注册:ClinicalTrials.gov 标识符:CTRI/2019/02/017802,日期为2019年2月25日。
{"title":"Efficacy of High-Volume Low-Concentration Intraperitoneal Bupivacaine Irrigation for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: Bupivacaine Irrigation for Analgesia.","authors":"Swati Panwar, Mona Arya, J S Dali, Kapil Chaudhary, Sushanto Neogi","doi":"10.1155/2024/4545400","DOIUrl":"https://doi.org/10.1155/2024/4545400","url":null,"abstract":"<p><p><b>Background:</b> Intraperitoneal irrigation with a low-volume, high-concentration local anaesthetic in laparoscopic cholecystectomy (LC) provides less pain relief. We investigated the impact of high-volume, low-concentration bupivacaine on postoperative pain and opioid requirement. <b>Methods:</b> Patients undergoing LC were randomised into Group B (20 mL of 0.5% bupivacaine in 480 mL normal saline) or Group S (500 mL of normal saline). Fifteen patients were included in both the groups but one patient was excluded from Group S because of bile duct injury. The primary outcome was Duration of Analgesia (DOA). The secondary outcomes were the Numeric Pain Rating Scale (NRS) at extubation, at 15 min, 30 min and 1, 2, 4, 8, 12 and 24 h. Cumulative rescue analgesics, incidence of postoperative nausea, vomiting and shoulder pain. <b>Results:</b> Mean (median/range) duration of analgesia was 6.45 ± 5.57 h (6/0.15-24) in Group B vs 3.18 ± 4.21 h (0.3/0.15-12) in Group S. Cumulative requirement of rescue analgesic was higher in saline group being 56.25 ± 33.92 mg for diclofenac and 83.57 ± 66.75 mg for tramadol vis-à-vis 40.9 ± 39.17 mg and 30.00 ± 52.78 mg, respectively, in bupivacaine group. <b>Conclusion:</b> Irrigation of the peritoneal cavity with high-volume low-concentration bupivacaine in LC increases the duration of analgesia and decreases the analgesic requirement in the postoperative period. <b>Trial Registration:</b> ClinicalTrials.gov identifier: CTRI/2019/02/017802 dated 25/02/2019.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"4545400"},"PeriodicalIF":1.6,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11540860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-18eCollection Date: 2024-01-01DOI: 10.1155/2024/7889539
Michael S Green, Michele Van Hal, Matthew Onimus, Christopher R Hoffman, Dhruv K C Goyal, Valeria Potigailo, Khuram S Kazmi
Low back pain is a common complaint among adults. The facet joint is a major source of lumbar pain, and therapeutic facet injections have gained popularity as a minimally invasive treatment option. In addition, magnetic resonance imaging (MRI) utilization for diagnosing low back pain has increased significantly over the past few decades. Facet synovitis is an entity characterized by edema and inflammatory changes affecting the facet joints, adjacent bone marrow, and surrounding soft tissues. Although its underlying etiology remains poorly understood, recent reports suggest a high incidence in patients with arthropathy and arthritis. It is essential to explore potential correlations between specific MRI findings and outcomes after lumbar facet injections. This investigation is particularly relevant for facet synovitis, given its inflammatory nature and the common use of anti-inflammatory agents in facet injections. We investigated associations between MRI evidence of facet arthropathy and/or synovitis and the degree of improvement in health-related outcome and pain scores after therapeutic facet injections. The review was conducted on patients who received bilateral therapeutic facet injections, excluding those with prior lumbar spinal surgery or transitional segments. Facet arthropathy and synovitis were assessed on MRI by two neuroradiologists, and postprocedure outcomes such as pain and function were compared using univariate and multivariate analyses based on MRI findings. Our retrospective review indicates that patients receiving facet injections experience greater mean reduction in daily activity and workability burden scores from back pain when facet synovitis is a known portion of their pathology. The authors pose that further study could help identify patient populations that are the best candidates for therapeutic intervention. This may ultimately improve delivery of care, cost efficacy, and patient satisfaction.
{"title":"Association Between MRI Findings of Facet Arthropathy and Synovitis With Health-Related Outcome and Pain Scores Following Therapeutic Lumbar Facet Injections.","authors":"Michael S Green, Michele Van Hal, Matthew Onimus, Christopher R Hoffman, Dhruv K C Goyal, Valeria Potigailo, Khuram S Kazmi","doi":"10.1155/2024/7889539","DOIUrl":"10.1155/2024/7889539","url":null,"abstract":"<p><p>Low back pain is a common complaint among adults. The facet joint is a major source of lumbar pain, and therapeutic facet injections have gained popularity as a minimally invasive treatment option. In addition, magnetic resonance imaging (MRI) utilization for diagnosing low back pain has increased significantly over the past few decades. Facet synovitis is an entity characterized by edema and inflammatory changes affecting the facet joints, adjacent bone marrow, and surrounding soft tissues. Although its underlying etiology remains poorly understood, recent reports suggest a high incidence in patients with arthropathy and arthritis. It is essential to explore potential correlations between specific MRI findings and outcomes after lumbar facet injections. This investigation is particularly relevant for facet synovitis, given its inflammatory nature and the common use of anti-inflammatory agents in facet injections. We investigated associations between MRI evidence of facet arthropathy and/or synovitis and the degree of improvement in health-related outcome and pain scores after therapeutic facet injections. The review was conducted on patients who received bilateral therapeutic facet injections, excluding those with prior lumbar spinal surgery or transitional segments. Facet arthropathy and synovitis were assessed on MRI by two neuroradiologists, and postprocedure outcomes such as pain and function were compared using univariate and multivariate analyses based on MRI findings. Our retrospective review indicates that patients receiving facet injections experience greater mean reduction in daily activity and workability burden scores from back pain when facet synovitis is a known portion of their pathology. The authors pose that further study could help identify patient populations that are the best candidates for therapeutic intervention. This may ultimately improve delivery of care, cost efficacy, and patient satisfaction.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"7889539"},"PeriodicalIF":1.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142493141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Preoxygenation prior to induction of general anesthesia is intended to increase the oxygen reserve in the lungs. This technique delays the onset of hypoxemia during the placement of the tracheal tube.
Objective: To observe the benefits of oxygen through nasal cannula when used as an adjunct during preoxygenation.
Methods: We enrolled 30 healthy volunteers and conducted a sequence of six preoxygenation tests. These included 3-minute tidal volume breathing and 8 vital capacity breaths, with and without oxygen flowing through the nasal cannula as an adjunct. Subjects were kept at a supine position with a face mask on their faces. Their baseline vitals were measured and end-tidal O2 (ETO2) was recorded at the end of each test. The comfort of each technique was also assessed.
Results: When comparing the efficacy of the two preoxygenation methods, we found that the addition of oxygen through the nasal cannula improved the efficacy of preoxygenation with both the 3-minute tidal volume breathing method and the 8 vital capacity method (p < 0.001). The three-minute tidal volume breathing technique had higher end-tidal oxygen when compared to the eight vital capacity breaths.
Conclusions: The administration of oxygen through a nasal cannula during preoxygenation improves the efficacy of preoxygenation in healthy volunteers. Tidal volume breathing for three minutes achieves a higher end-tidal oxygen concentration compared to eight vital capacity breaths over one minute.
{"title":"Use of a Nasal Cannula as a Preoxygenation Adjunct: A Randomized Crossover Study.","authors":"Murphy Joel, Suvajit Podder, Savan Kumar Nagesh, Ramyatha Aithal, Aditya R Devalla, Shaji Mathew","doi":"10.1155/2024/7873142","DOIUrl":"https://doi.org/10.1155/2024/7873142","url":null,"abstract":"<p><strong>Background: </strong>Preoxygenation prior to induction of general anesthesia is intended to increase the oxygen reserve in the lungs. This technique delays the onset of hypoxemia during the placement of the tracheal tube.</p><p><strong>Objective: </strong>To observe the benefits of oxygen through nasal cannula when used as an adjunct during preoxygenation.</p><p><strong>Methods: </strong>We enrolled 30 healthy volunteers and conducted a sequence of six preoxygenation tests. These included 3-minute tidal volume breathing and 8 vital capacity breaths, with and without oxygen flowing through the nasal cannula as an adjunct. Subjects were kept at a supine position with a face mask on their faces. Their baseline vitals were measured and end-tidal O<sub>2</sub> (ETO<sub>2</sub>) was recorded at the end of each test. The comfort of each technique was also assessed.</p><p><strong>Results: </strong>When comparing the efficacy of the two preoxygenation methods, we found that the addition of oxygen through the nasal cannula improved the efficacy of preoxygenation with both the 3-minute tidal volume breathing method and the 8 vital capacity method (<i>p</i> < 0.001). The three-minute tidal volume breathing technique had higher end-tidal oxygen when compared to the eight vital capacity breaths.</p><p><strong>Conclusions: </strong>The administration of oxygen through a nasal cannula during preoxygenation improves the efficacy of preoxygenation in healthy volunteers. Tidal volume breathing for three minutes achieves a higher end-tidal oxygen concentration compared to eight vital capacity breaths over one minute.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"7873142"},"PeriodicalIF":1.6,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-24eCollection Date: 2024-01-01DOI: 10.1155/2024/6049114
Sydney E S Brown, Michael Meyer, Andrea Meyer, Ruth Cassidy, Xinyi Zhao, Deborah Wagner, Laura Wetzel, Douglas A Colquhoun
Methods: Sugammadex vials were fractionated into 25, 50, or 100 mg aliquots, which would be distributed to anesthesia staff by pharmacy staff in approximate 2 mg/kg of actual body weight doses (±10%). We analyzed changes in sugammadex waste and dosing practices 1/1/2019 to 3/15/2023 pre/postintervention (4/1/2021). We gauged dose appropriateness using last train of four (TOF) prior to sugammadex administration.
Results: 7,889 patients 2-17 years (4,771 with documented TOF), ASA 1-4 receiving general anesthesia with a steroidal NMB medication and sugammadex reversal. Pre- and postintervention mean doses were 2.5 mg/kg (SD: 1.2) and 2.4 mg/kg (SD: 0.96), respectively. A smaller proportion of cases received standard 2 or 4 mg/kg doses (pre: 77.6 vs. post: 66.7%). Mean waste per case declined from 4.2 mg/kg (SD: 4.1) to 0.22 mg/kg (SD: 0.38). Among cases with 0 or 1 measured twitches on TOF that should receive at least 4 mg/kg, fewer received at least 3.6 mg/kg (post: 56.7% vs. pre: 66.8%), and a greater proportion received less than 2.2 mg/kg (post: 27.4% vs. pre: 20.7%). Among cases that should have received at least 2 mg/kg by TOF, the proportion of patients receiving more than 3.6 mg/kg declined from 9.5% to 5.2%. Discussion. Fractionating sugammadex vials was associated with decreases in waste, but not dose, and significant underdosing was more likely to occur. While vial fractionation could enable increased access to sugammadex and other costly medications, it may introduce unintended consequences.
{"title":"Weight-Based Standardized Sugammadex Dosing in Pediatrics: A Quality Improvement Initiative to Improve Compliance with Dosing Guidelines and Reduce Waste and Cost.","authors":"Sydney E S Brown, Michael Meyer, Andrea Meyer, Ruth Cassidy, Xinyi Zhao, Deborah Wagner, Laura Wetzel, Douglas A Colquhoun","doi":"10.1155/2024/6049114","DOIUrl":"10.1155/2024/6049114","url":null,"abstract":"<p><strong>Methods: </strong>Sugammadex vials were fractionated into 25, 50, or 100 mg aliquots, which would be distributed to anesthesia staff by pharmacy staff in approximate 2 mg/kg of actual body weight doses (±10%). We analyzed changes in sugammadex waste and dosing practices 1/1/2019 to 3/15/2023 pre/postintervention (4/1/2021). We gauged dose appropriateness using last train of four (TOF) prior to sugammadex administration.</p><p><strong>Results: </strong>7,889 patients 2-17 years (4,771 with documented TOF), ASA 1-4 receiving general anesthesia with a steroidal NMB medication and sugammadex reversal. Pre- and postintervention mean doses were 2.5 mg/kg (SD: 1.2) and 2.4 mg/kg (SD: 0.96), respectively. A smaller proportion of cases received standard 2 or 4 mg/kg doses (pre: 77.6 vs. post: 66.7%). Mean waste per case declined from 4.2 mg/kg (SD: 4.1) to 0.22 mg/kg (SD: 0.38). Among cases with 0 or 1 measured twitches on TOF that should receive at least 4 mg/kg, fewer received at least 3.6 mg/kg (post: 56.7% vs. pre: 66.8%), and a greater proportion received less than 2.2 mg/kg (post: 27.4% vs. pre: 20.7%). Among cases that should have received at least 2 mg/kg by TOF, the proportion of patients receiving more than 3.6 mg/kg declined from 9.5% to 5.2%. <i>Discussion</i>. Fractionating sugammadex vials was associated with decreases in waste, but not dose, and significant underdosing was more likely to occur. While vial fractionation could enable increased access to sugammadex and other costly medications, it may introduce unintended consequences.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"6049114"},"PeriodicalIF":1.6,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The aim was to evaluate the effect of preoperative anxiety on the sympathetic block that developed after spinal anesthesia and therefore the duration of motor and sensory blockade.
Materials and methods: After the approval of the ethics committee, 90 patients between the ages of 18 and 55 years who were to be operated under spinal anesthesia were included in the study. Preoperative anxiety of the patients was evaluated with the Spielberger trait and State Anxiety Scale and Visual Analog Scale (VAS). The Bromage scores of the patients were followed up intermittently. Onset time of sensory block, onset time of motor block, and motor block recovery time were recorded. Cases with bradycardia and hypotension were noted.
Results: No statistically significant correlation was found between the duration of motor block onset (5.81 ± 4 min), the sensory block onset time (0.89 ± 0.4 min), and the motor block recovery time (92.06 ± 36.9 min) with other variables. VAS (5.81 ± 2.5), STAI-1 (40.4 ± 9.8), and STAI-2 (41.69 ± 8.2) values had a statistically significant effect on the occurrence of bradycardia (14.4%). The variables of VAS, STAI-1, STAI-2, sensory block onset, motor block onset, and motor block recovery time were statistically significantly higher in women (mean 5.24 ± 2.4, 38.97 ± 9.9, 41.43 ± 8.7, 0.89 ± 0.42, 5.64 ± 3.82, and 88.77 ± 38.74 in males and mean 7.15 ± 2.1, 43.74 ± 8.9, 42.30 ± 7.0, 0.88 ± 0.27, 6.20 ± 4.35, and 99.70 ± 31.70 in females, respectively).
Conclusion: It was observed that preoperative anxiety had no effect on motor and sensory block onset and duration.
{"title":"The Effect of Preoperative Anxiety on Motor and Sensory Block Duration and Effectiveness in Spinal Anesthesia.","authors":"Yadigar Yılmaz, Esra Durmayuksel, Tuna Erturk, Ferda Yılmaz Inal, Dilek Metin Yamac, Aysin Ersoy","doi":"10.1155/2024/8827780","DOIUrl":"10.1155/2024/8827780","url":null,"abstract":"<p><strong>Introduction: </strong>The aim was to evaluate the effect of preoperative anxiety on the sympathetic block that developed after spinal anesthesia and therefore the duration of motor and sensory blockade.</p><p><strong>Materials and methods: </strong>After the approval of the ethics committee, 90 patients between the ages of 18 and 55 years who were to be operated under spinal anesthesia were included in the study. Preoperative anxiety of the patients was evaluated with the Spielberger trait and State Anxiety Scale and Visual Analog Scale (VAS). The Bromage scores of the patients were followed up intermittently. Onset time of sensory block, onset time of motor block, and motor block recovery time were recorded. Cases with bradycardia and hypotension were noted.</p><p><strong>Results: </strong>No statistically significant correlation was found between the duration of motor block onset (5.81 ± 4 min), the sensory block onset time (0.89 ± 0.4 min), and the motor block recovery time (92.06 ± 36.9 min) with other variables. VAS (5.81 ± 2.5), STAI-1 (40.4 ± 9.8), and STAI-2 (41.69 ± 8.2) values had a statistically significant effect on the occurrence of bradycardia (14.4%). The variables of VAS, STAI-1, STAI-2, sensory block onset, motor block onset, and motor block recovery time were statistically significantly higher in women (mean 5.24 ± 2.4, 38.97 ± 9.9, 41.43 ± 8.7, 0.89 ± 0.42, 5.64 ± 3.82, and 88.77 ± 38.74 in males and mean 7.15 ± 2.1, 43.74 ± 8.9, 42.30 ± 7.0, 0.88 ± 0.27, 6.20 ± 4.35, and 99.70 ± 31.70 in females, respectively).</p><p><strong>Conclusion: </strong>It was observed that preoperative anxiety had no effect on motor and sensory block onset and duration.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"8827780"},"PeriodicalIF":1.6,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-16eCollection Date: 2024-01-01DOI: 10.1155/2024/4838649
Marc Bozych, Nguyen K Tram, Julie Rice-Weimer, Richard S Cartabuke, Joseph D Tobias, Jamie Huffman, Christian Mpody, Joshua C Uffman
Background: Excessive operating room noise impairs communication, distracts from monitoring equipment, and may increase patient and provider stress.
Aim: This study investigates the effects of reduced noise on perioperative behavior in children undergoing general anesthesia and on anesthesia provider response time.
Methods: Healthy children (the American Society of Anesthesiologists class I-II), 2-8 years of age, and their anesthesia providers were randomized into a control or treatment group exposed to reduced stimulation during induction and emergence. Primary outcomes were patient behavior and provider response time. Secondary outcomes were postoperative pain scores, provider responses exceeding 30 seconds, and median and maximum noise exposure.
Results: 64 children (27 females and 37 males) were randomized into a control or treatment group, of whom 32 (50%) underwent tonsillectomy/adenoidectomy and 32 (50%) underwent dental procedures. The average age was 4.6 (SD 1.43) years. Children exposed to reduced noise were less likely to be "fussy about eating" (p=0.042), more "interested in what goes on around them" (p=0.008), and had fewer temper tantrums (p=0.004) on postoperative day one or two and on postoperative day five, six, or seven. No other differences were found between groups in behavioral assessment scores or provider response times.
Conclusions: Our study is the first to show that a low-stimulus environment improves postdischarge behavior. Provider response time was unaffected by reduced noise, and the average and peak noise exposure levels did not exceed national safety guidelines. This trial is registered with NCT03507855 and NCT03504553.
{"title":"Operating Room Noise Environment and Behavior in Children Undergoing General Anesthesia: A Randomized Controlled Trial.","authors":"Marc Bozych, Nguyen K Tram, Julie Rice-Weimer, Richard S Cartabuke, Joseph D Tobias, Jamie Huffman, Christian Mpody, Joshua C Uffman","doi":"10.1155/2024/4838649","DOIUrl":"10.1155/2024/4838649","url":null,"abstract":"<p><strong>Background: </strong>Excessive operating room noise impairs communication, distracts from monitoring equipment, and may increase patient and provider stress.</p><p><strong>Aim: </strong>This study investigates the effects of reduced noise on perioperative behavior in children undergoing general anesthesia and on anesthesia provider response time.</p><p><strong>Methods: </strong>Healthy children (the American Society of Anesthesiologists class I-II), 2-8 years of age, and their anesthesia providers were randomized into a control or treatment group exposed to reduced stimulation during induction and emergence. Primary outcomes were patient behavior and provider response time. Secondary outcomes were postoperative pain scores, provider responses exceeding 30 seconds, and median and maximum noise exposure.</p><p><strong>Results: </strong>64 children (27 females and 37 males) were randomized into a control or treatment group, of whom 32 (50%) underwent tonsillectomy/adenoidectomy and 32 (50%) underwent dental procedures. The average age was 4.6 (SD 1.43) years. Children exposed to reduced noise were less likely to be \"fussy about eating\" (<i>p</i>=0.042), more \"interested in what goes on around them\" (<i>p</i>=0.008), and had fewer temper tantrums (<i>p</i>=0.004) on postoperative day one or two and on postoperative day five, six, or seven. No other differences were found between groups in behavioral assessment scores or provider response times.</p><p><strong>Conclusions: </strong>Our study is the first to show that a low-stimulus environment improves postdischarge behavior. Provider response time was unaffected by reduced noise, and the average and peak noise exposure levels did not exceed national safety guidelines. This trial is registered with NCT03507855 and NCT03504553.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"4838649"},"PeriodicalIF":1.6,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142054632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-07eCollection Date: 2024-01-01DOI: 10.1155/2024/5555481
Yichun Gu, Jiajun Hao, Jiangna Wang, Peng Liang, Xinyi Peng, Xiaoxiao Qin, Yunwei Zhang, Da He
Background and Objective. The Bispectral Index (BIS) is utilized to guide the depth of anesthesia monitoring during surgical procedures. However, conflicting results regarding the benefits of BIS for depth of anesthesia monitoring have been reported in numerous studies. The purpose of this meta-analysis and systematic review was to assess the effectiveness of BIS for depth of anesthesia monitoring. Search Methods. A systematic search of Ovid-MEDLINE, Cochrane, and PubMed was conducted from inception to April 20, 2023. Clinical trial registers and grey literature were also searched, and reference lists of included studies, as well as related review articles, were manually reviewed. Selection Criteria. The inclusion criteria were randomized controlled trials without gender or age restrictions. The control groups used conventional monitoring, while the intervention groups utilized BIS monitoring. The exclusion criteria included duplicates, reviews, animal studies, unclear outcomes, and incomplete data. Data Collection and Analysis. Two independent reviewers screened the literature, extracted data, and assessed methodological quality, with analyses conducted using R 4.0 software. Main Results. Forty studies were included. In comparison to the conventional depth of anesthesia monitoring, BIS monitoring reduced the postoperative cognitive dysfunction risk (RR = 0.85, 95% CI: 0.73∼0.99, P = 0.04), shortened the eye-opening time (MD = -1.34, 95% CI: -2.06∼-0.61, P < 0.01), orientation recovery time (MD = -1.99, 95% CI: -3.62∼-0.36, P = 0.02), extubation time (MD = -2.54, 95% CI: -3.50∼-1.58, P < 0.01), and postanesthesia care unit stay time (MD = -7.11, 95% CI: -12.67∼-1.55, P = 0.01) and lowered the anesthesia drug dosage (SMD = -0.39, 95% CI: -0.63∼-0.15, P < 0.01). Conclusion. BIS can be used to effectively monitor the depth of anesthesia. Its use in general anesthesia enhances the effectiveness of both patient care and surgical procedures.
{"title":"Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis.","authors":"Yichun Gu, Jiajun Hao, Jiangna Wang, Peng Liang, Xinyi Peng, Xiaoxiao Qin, Yunwei Zhang, Da He","doi":"10.1155/2024/5555481","DOIUrl":"10.1155/2024/5555481","url":null,"abstract":"<p><p><i>Background and Objective</i>. The Bispectral Index (BIS) is utilized to guide the depth of anesthesia monitoring during surgical procedures. However, conflicting results regarding the benefits of BIS for depth of anesthesia monitoring have been reported in numerous studies. The purpose of this meta-analysis and systematic review was to assess the effectiveness of BIS for depth of anesthesia monitoring. <i>Search Methods</i>. A systematic search of Ovid-MEDLINE, Cochrane, and PubMed was conducted from inception to April 20, 2023. Clinical trial registers and grey literature were also searched, and reference lists of included studies, as well as related review articles, were manually reviewed. <i>Selection Criteria</i>. The inclusion criteria were randomized controlled trials without gender or age restrictions. The control groups used conventional monitoring, while the intervention groups utilized BIS monitoring. The exclusion criteria included duplicates, reviews, animal studies, unclear outcomes, and incomplete data. <i>Data Collection and Analysis</i>. Two independent reviewers screened the literature, extracted data, and assessed methodological quality, with analyses conducted using R 4.0 software. <i>Main Results</i>. Forty studies were included. In comparison to the conventional depth of anesthesia monitoring, BIS monitoring reduced the postoperative cognitive dysfunction risk (RR = 0.85, 95% CI: 0.73∼0.99, <i>P</i> = 0.04), shortened the eye-opening time (MD = -1.34, 95% CI: -2.06∼-0.61, <i>P</i> < 0.01), orientation recovery time (MD = -1.99, 95% CI: -3.62∼-0.36, <i>P</i> = 0.02), extubation time (MD = -2.54, 95% CI: -3.50∼-1.58, <i>P</i> < 0.01), and postanesthesia care unit stay time (MD = -7.11, 95% CI: -12.67∼-1.55, <i>P</i> = 0.01) and lowered the anesthesia drug dosage (SMD = -0.39, 95% CI: -0.63∼-0.15, <i>P</i> < 0.01). <i>Conclusion</i>. BIS can be used to effectively monitor the depth of anesthesia. Its use in general anesthesia enhances the effectiveness of both patient care and surgical procedures.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"5555481"},"PeriodicalIF":1.6,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11325011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Maternal satisfaction with pain management after cesarean delivery serves as an indicator of the quality of care. Assessing the level of satisfaction with postcesarean delivery pain management is paramount for both the mother and the healthcare institution. This study aimed to assess maternal satisfaction with postcesarean section pain management and associated factors at the Comprehensive Specialized Hospital in Northwest, Ethiopia, in 2023.
Methods: An institution-based cross-sectional study was conducted from April to June 2023, involving 424 study participants. A consecutive sampling method was utilized for participant selection. Data were entered into Epidata and then exported to SPSS version 25 for analysis. Descriptive and analytic statistics were employed. Both bivariable and multivariable logistic regression analyses were conducted to identify factors associated with maternal satisfaction regarding postcesarean section pain management. Variables with a p value of <0.2 in the bivariable analysis were included in the multivariable analysis. In the multivariable analysis, variables with a p value of <0.05 were considered statistically significant. Crude odds ratio and adjusted odds ratio with 95% confidence intervals were calculated to demonstrate the strength of the association.
Results: A total of 424 participants were included in the study with a response rate of 97.8%. The overall maternal satisfaction with postcesarean section pain management was 80.2% (95% CI: 76.1%-83.8%). Urban residence, elective cesarean section, mild pain, two and above previous history of cesarean section, and waiting less than 30 minutes to get analgesia were associated with maternal satisfaction with postcesarean section pain management.
Conclusion: The overall maternal satisfaction with postcesarean section pain management was promising. Urban residence, elective cesarean section, previous history of cesarean section, mild pain, and waiting less than 30 minutes to get analgesia were predictor factors for maternal satisfaction with postcaesarian section pain management. We recommend that the stakeholders should give attention to enhancing maternal satisfaction.
{"title":"Maternal Satisfaction and Associated Factors with Postcesarean Section Pain Management: A Cross-Sectional Study.","authors":"Biruk Adie Admass, Fikadu Tadesse Diress, Demeke Yilkal Fentie, Nigussie Simeneh Endalew","doi":"10.1155/2024/4885678","DOIUrl":"https://doi.org/10.1155/2024/4885678","url":null,"abstract":"<p><strong>Background: </strong>Maternal satisfaction with pain management after cesarean delivery serves as an indicator of the quality of care. Assessing the level of satisfaction with postcesarean delivery pain management is paramount for both the mother and the healthcare institution. This study aimed to assess maternal satisfaction with postcesarean section pain management and associated factors at the Comprehensive Specialized Hospital in Northwest, Ethiopia, in 2023.</p><p><strong>Methods: </strong>An institution-based cross-sectional study was conducted from April to June 2023, involving 424 study participants. A consecutive sampling method was utilized for participant selection. Data were entered into Epidata and then exported to SPSS version 25 for analysis. Descriptive and analytic statistics were employed. Both bivariable and multivariable logistic regression analyses were conducted to identify factors associated with maternal satisfaction regarding postcesarean section pain management. Variables with a <i>p</i> value of <0.2 in the bivariable analysis were included in the multivariable analysis. In the multivariable analysis, variables with a <i>p</i> value of <0.05 were considered statistically significant. Crude odds ratio and adjusted odds ratio with 95% confidence intervals were calculated to demonstrate the strength of the association.</p><p><strong>Results: </strong>A total of 424 participants were included in the study with a response rate of 97.8%. The overall maternal satisfaction with postcesarean section pain management was 80.2% (95% CI: 76.1%-83.8%). Urban residence, elective cesarean section, mild pain, two and above previous history of cesarean section, and waiting less than 30 minutes to get analgesia were associated with maternal satisfaction with postcesarean section pain management.</p><p><strong>Conclusion: </strong>The overall maternal satisfaction with postcesarean section pain management was promising. Urban residence, elective cesarean section, previous history of cesarean section, mild pain, and waiting less than 30 minutes to get analgesia were predictor factors for maternal satisfaction with postcaesarian section pain management. We recommend that the stakeholders should give attention to enhancing maternal satisfaction.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"4885678"},"PeriodicalIF":1.6,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11390219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-24eCollection Date: 2024-01-01DOI: 10.1155/2024/6418429
Mitra Golmohammadi, Shahryar Sane, Somayeh Ghavipanjeh Rezaei, Rana Hosseini, Enas R Alwaily, Beneen M Hussien, Ramin Mohammadpour, Nazila Rahmani, Behzad Kazemi Haki
Introduction: Emergence agitation (EA) is one of the common problems during recovery from general anesthesia, especially in children. In this study, we investigated the effect of dexmedetomidine on the control of agitation after anesthesia with sevoflurane in children.
Method: This randomized control-placebo, double-blind prospective clinical trial was conducted on seventy-six children between 2 and 7 years with ASA (American Society of Anesthesiologists) class I who were candidates for elective adenoidectomy surgery and tonsillectomy. Participants were selected by an available sampling method. Patients were randomly placed in one of the two groups D (dexmedetomidine 0.5 μg/kg infusion within ten minutes) or P (placebo: normal saline infusion within ten minutes). A four-point scale evaluated agitation. Pain evaluation was done by FLACC (faces, legs, activity, cry, and consolability). The statistical software was SPSS version 23. P < 0.05 was considered statistically significant.
Results: The level of agitation was significantly lower in the intervention group (P < 0.05), except after 40 minutes in the PACU (Post Anesthesia Care Unit) (P=1.00). Patients in the control group experienced high pain scores when admitted at PACU, 10, 20, and 30 minutes after admission at PACU (P < 0.05). Pethidine and metoclopramide prescriptions in the intervention group were lower than in the control group (P < 0.05). Shivering occurred in five patients in the intervention group and nine in the control groups (P=0.032). Hypotension that required intervention occurred in 3 patients in the intervention group and one in the control group (P=0.024).
Conclusion: Our trial demonstrated that the prescription of 0.5 μg/kg of dexmedetomidine within ten minutes after intubation significantly reduced the EA frequency, pain severity, analgesic consumption, and PONV (postoperative nausea and vomiting). However, it caused delays in the emergence from anesthesia. This trial is registered with IRCT20160430027677N14.
{"title":"Investigating the Effect of Dexmedetomidine in Controlling Postoperative Emergence Agitation in Children under Sevoflurane Anesthesia.","authors":"Mitra Golmohammadi, Shahryar Sane, Somayeh Ghavipanjeh Rezaei, Rana Hosseini, Enas R Alwaily, Beneen M Hussien, Ramin Mohammadpour, Nazila Rahmani, Behzad Kazemi Haki","doi":"10.1155/2024/6418429","DOIUrl":"10.1155/2024/6418429","url":null,"abstract":"<p><strong>Introduction: </strong>Emergence agitation (EA) is one of the common problems during recovery from general anesthesia, especially in children. In this study, we investigated the effect of dexmedetomidine on the control of agitation after anesthesia with sevoflurane in children.</p><p><strong>Method: </strong>This randomized control-placebo, double-blind prospective clinical trial was conducted on seventy-six children between 2 and 7 years with ASA (American Society of Anesthesiologists) class I who were candidates for elective adenoidectomy surgery and tonsillectomy. Participants were selected by an available sampling method. Patients were randomly placed in one of the two groups D (dexmedetomidine 0.5 <i>μ</i>g/kg infusion within ten minutes) or P (placebo: normal saline infusion within ten minutes). A four-point scale evaluated agitation. Pain evaluation was done by FLACC (faces, legs, activity, cry, and consolability). The statistical software was SPSS version 23. <i>P</i> < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The level of agitation was significantly lower in the intervention group (<i>P</i> < 0.05), except after 40 minutes in the PACU (Post Anesthesia Care Unit) (<i>P</i>=1.00). Patients in the control group experienced high pain scores when admitted at PACU, 10, 20, and 30 minutes after admission at PACU (<i>P</i> < 0.05). Pethidine and metoclopramide prescriptions in the intervention group were lower than in the control group (<i>P</i> < 0.05). Shivering occurred in five patients in the intervention group and nine in the control groups (<i>P</i>=0.032). Hypotension that required intervention occurred in 3 patients in the intervention group and one in the control group (<i>P</i>=0.024).</p><p><strong>Conclusion: </strong>Our trial demonstrated that the prescription of 0.5 <i>μ</i>g/kg of dexmedetomidine within ten minutes after intubation significantly reduced the EA frequency, pain severity, analgesic consumption, and PONV (postoperative nausea and vomiting). However, it caused delays in the emergence from anesthesia. This trial is registered with IRCT20160430027677N14.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"6418429"},"PeriodicalIF":1.6,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141892663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-05eCollection Date: 2024-01-01DOI: 10.1155/2024/2021671
Anne Strand Finstad, Conrad Arnfinn Bjørshol, Ingunn Aase, Jo Røislien, Randi Ballangrud
Background: In situ simulation-based team training of non-technical skills is considered an important initiative for preventing adverse events caused by poor teamwork among healthcare personnel. This study aimed to assess the non-technical skills of anaesthesia personnel before and after in situ simulation-based team training in a clinical setting.
Methods: The study was conducted from October 2020 to June 2021 using a quasiexperimental before and after design based on video-recorded observations and ratings of anaesthesia teams' non-technical skills during anaesthesia induction in the operating room before and shortly after in situ simulation-based team training. Anaesthesia personnel were divided into 20 teams and video recorded during anaesthesia induction. The Anaesthetists' Non-technical Skills (ANTS) system was used to score the teams' non-technical skills. A paired-sample t-test was used to assess the impact of the intervention on the anaesthesia teams' scores on the various ANTS categories. Interrater agreement between the two ANTS raters was assessed using weighted kappa.
Results: At the category level, the overall scores had a statistically significant increase in performance after simulation-based team training (3.48 vs. 3.71; p < 0.001). Furthermore, scores of five of the 15 elements were significantly different. Interrater agreement revealed moderate agreement between the two raters (weighted kappa = 0.51, p value <0.001).
Conclusion: The anaesthesia teams' increased non-technical skills after simulation-based team training may indicate the transfer of knowledge from training to clinical practice. The moderate agreement between the raters could be attributed to the subjective nature of the evaluation procedure. The ANTS was originally used as an individual assessment tool; however, this study has demonstrated its potential as a team assessment tool.
背景:对非技术性技能进行原位模拟团队培训被认为是预防医护人员因团队合作不佳而导致不良事件的重要举措。本研究旨在评估麻醉人员在临床环境中接受原位模拟团队培训前后的非技术性技能:该研究于 2020 年 10 月至 2021 年 6 月进行,采用了准实验性的前后设计,基于原位模拟团队培训前后对麻醉团队在手术室麻醉诱导过程中的非技术性技能进行视频录像观察和评分。麻醉人员被分成 20 个小组,在麻醉诱导过程中进行录像。使用麻醉师非技术技能(ANTS)系统对各小组的非技术技能进行评分。采用配对样本 t 检验来评估干预措施对麻醉团队在 ANTS 各项评分上的影响。采用加权卡帕法评估了两名ANTS评分员之间的相互一致性:结果:在类别水平上,模拟团队培训后的总分在统计学上有显著提高(3.48 vs. 3.71; p < 0.001)。此外,15 个要素中有 5 个要素的得分存在明显差异。两位评分者之间的相互评分一致度为中等(加权卡帕 = 0.51,P 值 结论:麻醉团队的技术水平在模拟培训后有了明显提高(3.48 对 3.71;P < 0.001):麻醉团队在接受模拟团队培训后,非技术性技能有所提高,这可能表明知识已从培训转移到临床实践中。评分者之间的一致性一般,这可能归因于评估程序的主观性。ANTS 最初是作为个人评估工具使用的,但本研究证明了其作为团队评估工具的潜力。
{"title":"Assessment of Anaesthesia Teams' Non-Technical Skills in Clinical Practice before and after Simulation-Based Team Training: A Quasiexperimental Study.","authors":"Anne Strand Finstad, Conrad Arnfinn Bjørshol, Ingunn Aase, Jo Røislien, Randi Ballangrud","doi":"10.1155/2024/2021671","DOIUrl":"10.1155/2024/2021671","url":null,"abstract":"<p><strong>Background: </strong>In situ simulation-based team training of non-technical skills is considered an important initiative for preventing adverse events caused by poor teamwork among healthcare personnel. This study aimed to assess the non-technical skills of anaesthesia personnel before and after in situ simulation-based team training in a clinical setting.</p><p><strong>Methods: </strong>The study was conducted from October 2020 to June 2021 using a quasiexperimental before and after design based on video-recorded observations and ratings of anaesthesia teams' non-technical skills during anaesthesia induction in the operating room before and shortly after in situ simulation-based team training. Anaesthesia personnel were divided into 20 teams and video recorded during anaesthesia induction. The Anaesthetists' Non-technical Skills (ANTS) system was used to score the teams' non-technical skills. A paired-sample <i>t</i>-test was used to assess the impact of the intervention on the anaesthesia teams' scores on the various ANTS categories. Interrater agreement between the two ANTS raters was assessed using weighted kappa.</p><p><strong>Results: </strong>At the category level, the overall scores had a statistically significant increase in performance after simulation-based team training (3.48 vs. 3.71; <i>p</i> < 0.001). Furthermore, scores of five of the 15 elements were significantly different. Interrater agreement revealed moderate agreement between the two raters (weighted kappa = 0.51, <i>p</i> value <0.001).</p><p><strong>Conclusion: </strong>The anaesthesia teams' increased non-technical skills after simulation-based team training may indicate the transfer of knowledge from training to clinical practice. The moderate agreement between the raters could be attributed to the subjective nature of the evaluation procedure. The ANTS was originally used as an individual assessment tool; however, this study has demonstrated its potential as a team assessment tool.</p>","PeriodicalId":7834,"journal":{"name":"Anesthesiology Research and Practice","volume":"2024 ","pages":"2021671"},"PeriodicalIF":1.6,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11245334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141615790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}