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Peri-articular Dextrose Prolotherapy: Investigating the Effect of Injection Site on Knee Osteoarthritis Pain: A Double-Blind, Randomized, Clinical Trial 关节周围葡萄糖注射疗法:调查注射部位对膝关节骨关节炎疼痛的影响:一项双盲、随机临床试验
Q2 Medicine Pub Date : 2024-03-27 DOI: 10.5812/aapm-140966
Shahrokh Ebnerasooli, Arash Barghi, Karim Nasseri, N. Moghimi
Background: Osteoarthritis (OA) is a chronic health condition that affects millions of people worldwide. It not only causes pain and physical limitations but also impacts mental health, sleep, work participation, and even mortality. Peri-articular dextrose prolotherapy has been shown to reduce knee osteoarthritis pain; however, the effect of injection sites on its effectiveness is not clear. Objectives: This study aimed to investigate the effect of injection points on pain intensity, joint stiffness, and physical activity in patients with knee osteoarthritis who underwent peri-articular dextrose prolotherapy. Methods: This double-blind clinical trial involved 26 patients with grade 2 and 3 bilateral knee osteoarthritis. Three times every one week, dextrose and lidocaine were injected as interventions. Injection sites were positioned within acupuncture points on one knee, but were relocated by 1.5 centimeters to the medial side of the same acupuncture points on the other knee. Pain intensity, joint stiffness, and physical activity were evaluated using the Visual Analog Pain Scale (VAS) and the Persian version of the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) before the intervention and at each follow-up visit at 1 and 2 months post-injection. Results: Pain intensity score, joint stiffness, physical performance, and WOMAC were significantly decreased one and two months after the intervention in both groups (P = 0.0001). The improvement in the patients of both groups was similar, and the two study groups did not have a statistically significant difference in terms of study outcomes (P = 0.37). Conclusions: Prolotherapy with dextrose is an effective treatment for knee osteoarthritis.
背景:骨关节炎(OA)是一种慢性疾病,影响着全球数百万人。它不仅会导致疼痛和身体受限,还会影响心理健康、睡眠、工作参与度甚至死亡率。关节周围葡萄糖增生疗法已被证明可减轻膝关节骨性关节炎疼痛,但注射部位对其效果的影响尚不明确。研究目的本研究旨在探讨注射点对接受关节周围葡萄糖增生疗法的膝骨关节炎患者的疼痛强度、关节僵硬度和体力活动的影响。研究方法这项双盲临床试验涉及 26 名 2 级和 3 级双侧膝关节骨关节炎患者。每周注射三次葡萄糖和利多卡因作为干预措施。注射部位位于一侧膝关节的穴位内,但将另一侧膝关节的穴位向内侧移动 1.5 厘米。在干预前以及注射后 1 个月和 2 个月的每次随访中,使用视觉模拟疼痛量表(VAS)和波斯语版的西安大略和麦克马斯特大学骨关节炎指数(WOMAC)对疼痛强度、关节僵硬度和体力活动进行评估。结果显示干预后 1 个月和 2 个月,两组患者的疼痛强度评分、关节僵硬度、体能表现和 WOMAC 均明显下降(P = 0.0001)。两组患者的改善情况相似,两组研究结果在统计学上无明显差异(P = 0.37)。结论使用葡萄糖进行推拿治疗是一种有效的膝关节骨性关节炎治疗方法。
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引用次数: 0
Comparison Between Erector Spinae Plane Block versus Serratus Anterior Plane Block Regarding Analgesia and Stress Response After Modified Radical Mastectomy: Randomized Controlled Trial 改良根治性乳房切除术后脊肌平面阻滞与前锯肌平面阻滞在镇痛和应激反应方面的比较:随机对照试验
Q2 Medicine Pub Date : 2024-03-26 DOI: 10.5812/aapm-142189
A. Bedewy, Maged Salah Mohamed, H. M. Sultan, M. S. Khalil
Background: Modified radical mastectomy (MRM) is the primary surgical treatment for breast cancer, yet it leads to significant postoperative pain. Objectives: This randomized controlled trial evaluates the effects of an erector spinae plane block (ESPB) versus a serratus anterior plane block (SAPB) on post-MRM pain management and stress response reduction. Methods: Sixty individuals scheduled for unilateral MRM under general anesthesia from October 2021 to October 2022 were divided into three groups. Group A comprised 20 patients who received ultrasound-guided ESPB (20 mL of 0.25% bupivacaine). Group B included 20 patients who received ultrasound-guided SAPB (20 mL of 0.25% bupivacaine). Group C was treated with intravenous morphine based on pain scores. Anesthesia was induced using 2 μg/kg of fentanyl and 2 - 3 mg/kg of propofol. The study compared the three groups regarding pain scores using a numerical rating scale, serum cortisol levels, total fentanyl, and morphine consumption, changes in mean arterial blood pressure (MAP) and heart rate (HR) during surgery, and the occurrence of postoperative complications. Results: Statistically significant reductions in pain scores were observed in group A compared to groups B and C. Moreover, group A exhibited a significant decrease in postoperative morphine consumption, serum cortisol levels 1 hour post-surgery (P = 0.021), MAP, and postoperative vomiting and nausea compared to group B. Furthermore, groups A and B showed statistically significant improvements in all parameters compared to group C. Conclusions: The study demonstrates that ESPB provides superior analgesic effects compared to SAPB in patients undergoing MRM, with reduced morphine use and lower postoperative cortisol levels. Both blocks offer more effective pain control than intravenous morphine alone.
背景:改良根治性乳房切除术(MRM)是乳腺癌的主要外科治疗方法,但它会导致术后明显的疼痛。研究目的本随机对照试验评估了竖脊肌平面阻滞(ESPB)与前锯肌平面阻滞(SAPB)对乳腺根治术后疼痛控制和应激反应减轻的效果。方法:将 2021 年 10 月至 2022 年 10 月期间计划在全身麻醉下进行单侧 MRM 的 60 名患者分为三组。A 组包括 20 名接受超声引导 ESPB(20 毫升 0.25% 布比卡因)的患者。B 组的 20 名患者在超声引导下接受 SAPB(20 毫升 0.25% 布比卡因)治疗。C 组患者根据疼痛评分静脉注射吗啡。麻醉诱导使用 2 μg/kg 芬太尼和 2 - 3 mg/kg 丙泊酚。研究比较了三组患者的疼痛评分、血清皮质醇水平、芬太尼总量、吗啡消耗量、术中平均动脉血压(MAP)和心率(HR)的变化以及术后并发症的发生情况。研究结果此外,与 B 组相比,A 组在术后吗啡用量、术后 1 小时血清皮质醇水平(P = 0.021)、MAP 以及术后呕吐和恶心方面均有明显下降。此外,与 C 组相比,A 组和 B 组在所有参数上都有显著的统计学改善:该研究表明,在接受 MRM 的患者中,ESPB 的镇痛效果优于 SAPB,吗啡用量减少,术后皮质醇水平降低。与静脉注射吗啡相比,两种阻滞都能提供更有效的疼痛控制。
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引用次数: 0
Validity of Ultrasound in Correlation with Cormack-Lehane Grading in Obese Patients: A Cross-Sectional Study 超声波与肥胖患者 Cormack-Lehane 分级的相关性:横断面研究
Q2 Medicine Pub Date : 2024-03-24 DOI: 10.5812/aapm-142701
Ahmed El-Tawansy, Ahmed Mohamed Elnajar, Hossam Abdel Baky Mahmoud, Mohamed Ibrahim Amin, A. Bedewy
Background: Ultrasound (US) of the upper airway has the potential to be a valuable addition to traditional clinical evaluation methods. Objectives: This work aimed to assess the validity of US in correlation with Cormack-Lehane grading (CLG) in obese patients. Methods: This cross-sectional work was performed on 78 patients ranging in age between 21 and 60 years, both genders with the American Society of Anesthesiologists (ASA) II-III individuals and body mass index (BMI) 30 kg/m² or more, under general anesthesia with endotracheal tube placement. Each separate finding by the US and conventional clinical airway assessment methods before anesthesia induction correlated to the CLG of the same patient after the induction of anesthesia. Grades III and IV are categorized as difficult laryngoscopy. Results: A significant positive association existed among CLG and duration of US measures, pre-epiglottis spaces (Pre-E) ratios, to the distance between a point mid away vocal cords and epiglottis, Pre-E, ratio of hyomental distance extension/hyomental distance neutral and Mallampati; however, there was a significant negative correlation with skin to anterior commissure, hyomental distance extension, hyomental distance neutral, sternomental distance, and thyromental distance (P < 0.05). The ratio between Pre-E over the distance between the epiglottis and a point midway through the vocal cords at cut-off > 2.23 can discriminate difficult laryngoscopy with sensitivity 100% and specificity 100% and area under the curve of 1. Conclusions: The sonographic assessment of the upper airway aids in predicting individuals who might have challenges with airway management. A reliable indicator of a challenging laryngoscopy was the sonographic parameter ratio of Pre-E to the distance between the vocal cords' midway point and the epiglottis.
背景:上气道超声波(US)有望成为传统临床评估方法的重要补充。目的:本研究旨在评估 US 与 Cormack-Lehane 分级相关性的有效性:本研究旨在评估肥胖患者上气道超声检查与 Cormack-Lehane 分级(CLG)的相关性。方法这项横断面研究对 78 名年龄介于 21 岁至 60 岁之间、美国麻醉医师协会(ASA)II-III 级、体重指数(BMI)30 公斤/平方米或以上的男女患者进行了研究,他们都接受了气管插管全身麻醉。麻醉诱导前通过 US 和传统临床气道评估方法得出的每项单独结果都与麻醉诱导后同一患者的 CLG 相关联。III 级和 IV 级被归类为困难喉镜检查。结果:CLG与US测量的持续时间、会厌前间隙(Pre-E)比值、声带与会厌中间点的距离、Pre-E、会厌间距延长/会厌间距中性比值和Mallampati之间存在明显的正相关;但与皮肤到前会厌、会厌间距延长、会厌间距中性、胸骨间距和甲状腺间距之间存在明显的负相关(P < 0.05)。会厌与声带中点之间距离的 Pre-E 比值(临界值 > 2.23)可判别喉镜检查困难,灵敏度为 100%,特异度为 100%,曲线下面积为 1。 结论:上气道超声评估有助于预测气道管理中可能遇到困难的患者。声学参数 Pre-E 与声带中点和会厌之间距离的比值是喉镜检查困难的可靠指标。
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引用次数: 0
Comparing Apotel and Remifentanil for Multimodal Patient-Controlled Analgesia in Postoperative Pain Management Following Total Knee Arthroplasty Surgery: A Randomized Controlled Trial 在全膝关节置换术后疼痛控制中比较阿博泰和雷米芬太尼的多模式患者自控镇痛:随机对照试验
Q2 Medicine Pub Date : 2024-03-18 DOI: 10.5812/aapm-141975
Seyed Ali Golrokh Moghadam, Amin Tajerian, Behnam Mahmoudieh, Mohsen Parsi Khamene, Alireza Kamali
Background: Total knee arthroplasty (TKA) is a standard surgical procedure for individuals with debilitating knee arthritis. Effective postoperative pain management is essential for successful recovery, although traditional opioid-based methods have limitations. Objectives: This study aimed to compare the efficacy of Apotel and Remifentanil patient-controlled analgesia in managing postoperative pain after TKA. Methods: This double-blind, randomized, controlled clinical trial took place at Amir-al-Momenin and Qods Hospitals in Arak, Iran, spanning from June 2022 to September 2023. Sixty-two eligible patients scheduled for knee joint replacement were randomly assigned to receive either Apotel (Group A) or Remifentanil (Group R) as part of multimodal analgesia administered via a pain pump for postoperative pain relief in TKA. The study assessed hemodynamic parameters, pain levels (measured using the Visual Analog Scale), analgesic duration, and narcotic consumption. Statistical analyses were performed using SPSS v.27 and Plotly. Results: Subjects exhibited no statistically significant differences in age, gender distribution, duration of surgery, or anesthesia. The hemodynamic status assessment in the recovery room showed no significant differences in SPO2, PR, or MAP between the groups. However, Remifentanil demonstrated superior effectiveness in reducing pain over 24 hours post TKA surgery compared to Apotel, as evidenced by lower average Visual Analog Scale (VAS) scores (P < 0.001), longer duration without the need for narcotic painkillers (P < 0.001), and lower cumulative opioid analgesic consumption in Group R (P < 0.001). Conclusions: Remifentanil demonstrates superior pain control in a multimodal pain management approach compared to Apotel, providing sustained pain reduction over 24 hours post-surgery. Moreover, Remifentanil offers longer-lasting pain relief and results in lower cumulative narcotic painkiller consumption compared to Apotel.
背景:全膝关节置换术(TKA)是治疗膝关节炎患者的标准手术方法。有效的术后疼痛管理是成功康复的关键,但传统的阿片类药物治疗方法存在局限性。研究目的本研究旨在比较 Apotel 和 Remifentanil 患者自控镇痛在控制 TKA 术后疼痛方面的疗效。方法:这项双盲、随机对照临床试验于 2022 年 6 月至 2023 年 9 月在伊朗阿拉克的 Amir-al-Momenin 和 Qods 医院进行。62名符合条件的膝关节置换术患者被随机分配到阿博泰(A组)或雷米芬太尼(R组)组,作为通过镇痛泵进行多模式镇痛的一部分,以缓解TKA术后疼痛。研究评估了血液动力学参数、疼痛程度(使用视觉模拟量表测量)、镇痛持续时间和麻醉剂消耗量。统计分析使用 SPSS v.27 和 Plotly 进行。结果受试者在年龄、性别分布、手术持续时间或麻醉方面没有明显的统计学差异。在恢复室进行的血液动力学状态评估显示,两组之间的 SPO2、PR 或 MAP 没有明显差异。然而,与阿博泰相比,瑞芬太尼在减轻 TKA 术后 24 小时内的疼痛方面表现出更高的有效性,这体现在 R 组的平均视觉模拟量表 (VAS) 评分更低(P < 0.001)、无需使用麻醉止痛药的持续时间更长(P < 0.001)以及阿片类镇痛药的累积用量更低(P < 0.001)。结论在多模式疼痛管理方法中,雷米芬太尼的镇痛效果优于阿博泰,可在术后 24 小时内持续减轻疼痛。此外,与阿博泰尔相比,瑞芬太尼的止痛效果更持久,麻醉止痛药的累积用量也更低。
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引用次数: 0
Professional Attitudes and Practice of Pediatric Dentists About the Use of Local Anesthesia for the Treatment of Children Under General Anesthesia 儿科牙医对全身麻醉下使用局部麻醉治疗儿童的专业态度和做法
Q2 Medicine Pub Date : 2024-03-17 DOI: 10.5812/aapm-143076
Reyhaneh Faghihian, Aryana Golabbakhsh, Elahe Asnaashari
Background: The application of local anesthesia in dental surgeries conducted under general anesthesia poses a challenge in pediatric dentistry. There is a lack of consensus regarding the benefits and drawbacks of using general anesthesia in this field. Objectives: The purpose of this study was to assess the attitudes and practices of pediatric dentists regarding the use of local anesthesia for dental treatments in children under general anesthesia in Iran. Methods: This cross-sectional study involved 110 pediatric dentists from across Iran. The dentists' professional attitudes and practices were assessed using a specially designed questionnaire for this study. The questionnaire was distributed through the Line press system, and the data were analyzed following collection. Results: Regarding professional practices, 34.5% of specialists refrained from using local anesthesia. The most frequent application of local anesthesia was observed in tooth extractions. The preferred local anesthetic agent was 2% lidocaine with 1:100 000 epinephrine. A lower dose than that used in outpatient settings was administered, and most specialists allowed sufficient time for the anesthesia to take effect. Conclusions: This study revealed that opinions and attitudes towards the use of local anesthesia in the dental treatment of children under general anesthesia vary across different specialties and are significantly influenced by the patient's condition, type of treatment, and practice techniques.
背景:在全身麻醉下进行的牙科手术中应用局部麻醉是儿童牙科面临的一项挑战。关于在该领域使用全身麻醉的利弊还缺乏共识。研究目的本研究旨在评估伊朗儿童牙科医生对全身麻醉下儿童牙科治疗使用局部麻醉的态度和做法。研究方法这项横断面研究涉及伊朗各地的 110 名儿童牙医。牙医的专业态度和做法是通过为本研究专门设计的调查问卷进行评估的。问卷通过线性新闻系统发放,数据收集后进行分析。结果:在专业实践方面,34.5% 的专家不使用局部麻醉。局部麻醉最常应用于拔牙。首选的局麻药是 2% 利多卡因加 1:100 000 肾上腺素。使用的剂量低于门诊使用的剂量,大多数专科医生都会留出足够的时间让麻醉起效。结论:这项研究表明,不同专科对在全身麻醉下使用局部麻醉进行儿童牙科治疗的看法和态度各不相同,并且受到患者病情、治疗类型和实践技术的显著影响。
{"title":"Professional Attitudes and Practice of Pediatric Dentists About the Use of Local Anesthesia for the Treatment of Children Under General Anesthesia","authors":"Reyhaneh Faghihian, Aryana Golabbakhsh, Elahe Asnaashari","doi":"10.5812/aapm-143076","DOIUrl":"https://doi.org/10.5812/aapm-143076","url":null,"abstract":"Background: The application of local anesthesia in dental surgeries conducted under general anesthesia poses a challenge in pediatric dentistry. There is a lack of consensus regarding the benefits and drawbacks of using general anesthesia in this field. Objectives: The purpose of this study was to assess the attitudes and practices of pediatric dentists regarding the use of local anesthesia for dental treatments in children under general anesthesia in Iran. Methods: This cross-sectional study involved 110 pediatric dentists from across Iran. The dentists' professional attitudes and practices were assessed using a specially designed questionnaire for this study. The questionnaire was distributed through the Line press system, and the data were analyzed following collection. Results: Regarding professional practices, 34.5% of specialists refrained from using local anesthesia. The most frequent application of local anesthesia was observed in tooth extractions. The preferred local anesthetic agent was 2% lidocaine with 1:100 000 epinephrine. A lower dose than that used in outpatient settings was administered, and most specialists allowed sufficient time for the anesthesia to take effect. Conclusions: This study revealed that opinions and attitudes towards the use of local anesthesia in the dental treatment of children under general anesthesia vary across different specialties and are significantly influenced by the patient's condition, type of treatment, and practice techniques.","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"3 9‐10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140235452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Etomidate Versus Midazolam-Sodium Thiopental on Attenuating the Cardiovascular Response to Laryngoscopy and Tracheal Intubation 依托咪酯与咪达唑仑-硫喷妥钠对减轻喉镜检查和气管插管时心血管反应的影响
Q2 Medicine Pub Date : 2024-03-14 DOI: 10.5812/aapm-143382
H. Shetabi, Darioush Moradi Farsani, Zahra Allafchian
Background: Laryngoscopy and tracheal intubation lead to an increased sympathetic reflex response, which is associated with increased heart rate and blood pressure. This response can be detrimental in patients with myocardial ischemia. This study aimed to investigate the effects of etomidate in comparison to a combination of midazolam and sodium thiopental in reducing the sympathetic response to laryngoscopy and tracheal intubation. Methods: This double-blind, randomized clinical trial study was conducted on two groups of 39 candidates for elective surgery under general anesthesia. Anesthesia was induced by etomidate (E) 0.3 mg/kg in the first group and sodium thiopental 2.5 mg/kg and midazolam 0.075 mg/kg in the second group (TM); then, the patients were intubated. Laryngoscopy findings and cardiovascular response were evaluated during the study. Finally, the data were analyzed using SPSS version 23 (IBM SPSS, Armonk, NY, USA). Results: There was no significant difference between the two groups in terms of age (P = 0.82), weight (P = 0.42), height (P = 0.201), body mass index (P = 0.78), gender (P = 0.65), American Society of Anesthesiologists (ASA) physical status (P = 0.36), and laryngoscopy view grading (P = 0.83). The average laryngoscopy time in the E group was less than the TM group (P = 0.019). In the TM group, at 10 minutes after intubation, mean diastolic blood pressure (P = 0.029) and mean arterial blood pressure (P = 0.023) were significantly lower; however, at other times, there was no significant difference between the two groups (P > 0.05). There was no significant difference between the two groups in terms of adverse responses to laryngoscopy and intubation (P = 0.19). Conclusions: The results of the present study showed that etomidate (E) and a combination of midazolam-sodium thiopental (TM) acted similarly in attenuating the cardiovascular response to laryngoscopy and tracheal intubation, and it seems that TM can be used instead of E if needed.
背景:喉镜检查和气管插管会导致交感神经反射反应增强,这与心率和血压升高有关。这种反应对心肌缺血患者不利。本研究旨在探讨依托咪酯与咪达唑仑和硫喷妥钠联合用药相比,在减少喉镜检查和气管插管时交感神经反应方面的效果。方法:这项双盲、随机临床试验研究针对两组 39 名在全身麻醉下进行择期手术的患者。第一组使用依托咪酯 0.3 毫克/千克诱导麻醉,第二组(TM)使用硫喷妥钠 2.5 毫克/千克和咪达唑仑 0.075 毫克/千克诱导麻醉,然后给患者插管。研究期间对喉镜检查结果和心血管反应进行了评估。最后,使用 SPSS 23 版本(IBM SPSS,美国纽约阿蒙克)对数据进行分析。结果两组患者在年龄(P = 0.82)、体重(P = 0.42)、身高(P = 0.201)、体重指数(P = 0.78)、性别(P = 0.65)、美国麻醉医师协会(ASA)身体状况(P = 0.36)和喉镜视图分级(P = 0.83)方面无明显差异。E 组的平均喉镜检查时间少于 TM 组(P = 0.019)。在 TM 组中,插管后 10 分钟的平均舒张压(P = 0.029)和平均动脉血压(P = 0.023)显著较低;但在其他时间,两组之间没有显著差异(P > 0.05)。在喉镜检查和插管的不良反应方面,两组之间没有明显差异(P = 0.19)。结论:本研究结果表明,依托咪酯(E)和咪达唑仑-硫喷妥钠联合用药(TM)在减轻喉镜检查和气管插管时的心血管反应方面作用相似,似乎在必要时可以用TM代替E。
{"title":"Effect of Etomidate Versus Midazolam-Sodium Thiopental on Attenuating the Cardiovascular Response to Laryngoscopy and Tracheal Intubation","authors":"H. Shetabi, Darioush Moradi Farsani, Zahra Allafchian","doi":"10.5812/aapm-143382","DOIUrl":"https://doi.org/10.5812/aapm-143382","url":null,"abstract":"Background: Laryngoscopy and tracheal intubation lead to an increased sympathetic reflex response, which is associated with increased heart rate and blood pressure. This response can be detrimental in patients with myocardial ischemia. This study aimed to investigate the effects of etomidate in comparison to a combination of midazolam and sodium thiopental in reducing the sympathetic response to laryngoscopy and tracheal intubation. Methods: This double-blind, randomized clinical trial study was conducted on two groups of 39 candidates for elective surgery under general anesthesia. Anesthesia was induced by etomidate (E) 0.3 mg/kg in the first group and sodium thiopental 2.5 mg/kg and midazolam 0.075 mg/kg in the second group (TM); then, the patients were intubated. Laryngoscopy findings and cardiovascular response were evaluated during the study. Finally, the data were analyzed using SPSS version 23 (IBM SPSS, Armonk, NY, USA). Results: There was no significant difference between the two groups in terms of age (P = 0.82), weight (P = 0.42), height (P = 0.201), body mass index (P = 0.78), gender (P = 0.65), American Society of Anesthesiologists (ASA) physical status (P = 0.36), and laryngoscopy view grading (P = 0.83). The average laryngoscopy time in the E group was less than the TM group (P = 0.019). In the TM group, at 10 minutes after intubation, mean diastolic blood pressure (P = 0.029) and mean arterial blood pressure (P = 0.023) were significantly lower; however, at other times, there was no significant difference between the two groups (P > 0.05). There was no significant difference between the two groups in terms of adverse responses to laryngoscopy and intubation (P = 0.19). Conclusions: The results of the present study showed that etomidate (E) and a combination of midazolam-sodium thiopental (TM) acted similarly in attenuating the cardiovascular response to laryngoscopy and tracheal intubation, and it seems that TM can be used instead of E if needed.","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"19 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140243162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Vibration on Acute and Chronic Back Pain After Spinal Anesthesia: A Randomized Clinical Trial 振动对脊柱麻醉后急性和慢性背痛的影响:随机临床试验
Q2 Medicine Pub Date : 2024-03-11 DOI: 10.5812/aapm-143528
Shervin Shahinpour, Fatemeh Refahi, Nader Ali Nazemian
Background: Post-spinal anesthesia back pain often initiates with needle insertion and may persist for months, particularly among young women following cesarean section. Mechanical vibration has been proposed as an effective method to alleviate this pain. Objectives: The study aimed to evaluate the impact of vibration on reducing pain experienced during needle insertion, as well as its effects one week and one-month post-puncture. Methods: This randomized clinical trial enrolled patients undergoing spinal anesthesia for various surgical procedures. Patients were randomly assigned to either receive routine spinal anesthesia or spinal anesthesia combined with vibration. Demographic data were collected, and pain levels during needle insertion and back pain were assessed using a visual analog scale (VAS). Results: A total of 64 patients were included in the study. There were no significant differences between the two groups in terms of the number of attempts required for needle insertion (P = 0.341), the predominant anatomical level, or the needle approach (midline or paramedian). Ultimately, pain experienced during needle insertion, back pain after one week, and back pain after one month did not differ significantly between the two groups (P = 0.562, P = 0.14, and P = 0.267, respectively) Conclusions: The results of the present study showed that vibration at the site of needle insertion during spinal anesthesia had no effect on acute and chronic back pain on subsequent follow-up due to spinal anesthesia.
背景:椎管内麻醉后的背痛通常在插针时开始,并可能持续数月之久,尤其是剖腹产后的年轻女性。机械振动被认为是缓解这种疼痛的有效方法。研究目的本研究旨在评估振动对减轻进针时疼痛的影响,以及对进针后一周和一个月疼痛的影响。方法: 随机临床试验这项随机临床试验招募了因各种外科手术而接受脊髓麻醉的患者。患者被随机分配接受常规脊髓麻醉或脊髓麻醉结合振动。试验收集了患者的人口统计学数据,并使用视觉模拟量表(VAS)评估了插针时的疼痛程度和背部疼痛。结果共有 64 名患者参与了研究。两组患者在进针次数(P = 0.341)、主要解剖层次或进针方式(中线或旁线)方面均无明显差异。最终,两组患者在进针时的疼痛、一周后的背痛和一个月后的背痛没有显著差异(分别为 P = 0.562、P = 0.14 和 P = 0.267):本研究结果表明,脊髓麻醉时针头插入部位的振动对脊髓麻醉引起的急性和慢性背痛没有影响。
{"title":"Effect of Vibration on Acute and Chronic Back Pain After Spinal Anesthesia: A Randomized Clinical Trial","authors":"Shervin Shahinpour, Fatemeh Refahi, Nader Ali Nazemian","doi":"10.5812/aapm-143528","DOIUrl":"https://doi.org/10.5812/aapm-143528","url":null,"abstract":"Background: Post-spinal anesthesia back pain often initiates with needle insertion and may persist for months, particularly among young women following cesarean section. Mechanical vibration has been proposed as an effective method to alleviate this pain. Objectives: The study aimed to evaluate the impact of vibration on reducing pain experienced during needle insertion, as well as its effects one week and one-month post-puncture. Methods: This randomized clinical trial enrolled patients undergoing spinal anesthesia for various surgical procedures. Patients were randomly assigned to either receive routine spinal anesthesia or spinal anesthesia combined with vibration. Demographic data were collected, and pain levels during needle insertion and back pain were assessed using a visual analog scale (VAS). Results: A total of 64 patients were included in the study. There were no significant differences between the two groups in terms of the number of attempts required for needle insertion (P = 0.341), the predominant anatomical level, or the needle approach (midline or paramedian). Ultimately, pain experienced during needle insertion, back pain after one week, and back pain after one month did not differ significantly between the two groups (P = 0.562, P = 0.14, and P = 0.267, respectively) Conclusions: The results of the present study showed that vibration at the site of needle insertion during spinal anesthesia had no effect on acute and chronic back pain on subsequent follow-up due to spinal anesthesia.","PeriodicalId":7841,"journal":{"name":"Anesthesiology and Pain Medicine","volume":"19 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case Report on Pneumocephalus That Occurred Following an Epidural Ozone Injection During Percutaneous Lumbar Disc Decompression Surgery 经皮腰椎间盘减压术中硬膜外臭氧注射后发生气胸的病例报告
Q2 Medicine Pub Date : 2024-03-07 DOI: 10.5812/aapm-142519
Karim Hemati, Parniyan Hematy, Saeid Rahimi Ghasabeh, Ali Shokooh
: Spinal decompression is a common procedure in spinal, neurosurgery, and orthopedic surgery. While there are a number of known complications associated with it, pneumocephalus (air in the brain) is generally not a recognized complication postoperatively. However, in rare cases, it can occur as a result of spinal decompression surgery. We describe a case of a 54-year-old female patient who developed pneumocephalus following percutaneous lumbar disc decompression surgery of the lumbar spine. The patient presented to the emergency department 3 hours after discharge with severe restlessness, cognitive impairment, nausea, vomiting, and lack of balance. During symptomatic treatment in the emergency department and 1 hour after taking oxygen, the patient’s vital signs improved. Before discharge, a computed tomography (CT) scan was taken again, which showed the disappearance of radiological symptoms. The patient was discharged 12 hours after hospitalization with suitable clinical conditions. Obtaining urgent imaging tests (magnetic resonance imaging [MRI] or CT) at the cranial and spinal levels, along with an electroencephalogram, allows us to diagnose the problem and determine the appropriate course of treatment, whether pharmacological or surgical.
:脊柱减压术是脊柱、神经外科和整形外科的常见手术。虽然有许多已知的相关并发症,但脑积气通常不是公认的术后并发症。不过,在极少数情况下,脊柱减压手术也可能导致气胸。我们描述了一例 54 岁女性患者在腰椎经皮腰椎间盘减压术后出现气胸的病例。患者在出院 3 小时后因严重烦躁不安、认知障碍、恶心、呕吐和缺乏平衡感而到急诊科就诊。在急诊科对症治疗期间和吸氧 1 小时后,患者的生命体征有所改善。出院前,再次进行了计算机断层扫描(CT),结果显示放射性症状消失。住院 12 小时后,患者出院,临床状况良好。在头颅和脊柱层面进行紧急成像检查(磁共振成像 [MRI] 或 CT),同时进行脑电图检查,可以让我们诊断出问题所在,并确定适当的治疗方案,无论是药物治疗还是手术治疗。
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引用次数: 0
Assessment of Ganglion Impar Block Effect on Treatment Results of Coccydynia: A Cross-sectional Study 评估神经节假体阻滞对尾骨神经痛治疗效果的影响:横断面研究
Q2 Medicine Pub Date : 2024-03-07 DOI: 10.5812/aapm-142137
Aliakbar Nasiri, Farzad Farajzadeh Vajari, Shahryar Sane, R. Afsargharehbagh
Background: The ganglion impar block is a minimally invasive technique used for alleviating pain associated with coccydynia. Objectives: This research evaluates the effectiveness of the ganglion impar block in treating patients with coccydynia who have not benefited from conservative treatments. Methods: This cross-sectional analysis reviewed the clinical records of coccydynia patients who received ganglion impar block injections at Urmia Imam Khomeini Hospital, Urmia, Iran, between 2020 and 2022. Data regarding age, gender, body mass index (BMI), onset of pain, and levels of patient satisfaction post-treatment were gathered from the medical records. Results: The study comprised 26 patients, with 4 (15.4%) being male and 22 (84.6%) female. The average age and BMI were 39.15 ± 14.24 years and 28.91 ± 2.14 kg/m2, respectively, which did not show significant variation (P = 0.19). The average Visual Analogue Scale (VAS) score before the ganglion impar block was 6.23 ± 2.35, which reduced to 4.47 ± 2.41 immediately after the procedure. At the 1-month follow-up, the average VAS score had further decreased to 3.47 ± 0.79. The decrease in VAS scores, both immediately after the procedure and at the 1-month follow-up, was statistically significant. The success rate of the block (defined as a reduction in pain of at least 20% from the baseline) was significantly high immediately and one-month post-procedure (P < 0.001). Out of the 26 patients treated with the impar block, satisfaction rates were 42.3% excellent, 27% good, 19.2% fair, and 11.5% poor. Conclusions: The study endorses the trans-sacro-coccygeal “needle inside needle” method for providing relief to patients suffering from coccydynia. The findings revealed significant patient satisfaction, with the majority describing their experience as excellent.
背景:神经节阻滞是一种微创技术,用于缓解尾骨痛相关的疼痛。研究目的本研究评估了神经节阻滞对保守治疗无效的尾骨痛患者的治疗效果。研究方法这项横断面分析回顾了 2020 年至 2022 年期间在伊朗乌尔米亚伊玛目霍梅尼医院接受神经节阻滞注射的尾骨痛患者的临床记录。从病历中收集了有关年龄、性别、体重指数(BMI)、疼痛发作和治疗后患者满意度的数据。研究结果研究对象包括 26 名患者,其中男性 4 名(占 15.4%),女性 22 名(占 84.6%)。平均年龄和体重指数分别为(39.15 ± 14.24)岁和(28.91 ± 2.14)kg/m2,差异不显著(P = 0.19)。神经节阻滞前的平均视觉模拟量表(VAS)评分为(6.23±2.35)分,术后立即降至(4.47±2.41)分。在 1 个月的随访中,VAS 平均值进一步降至 3.47 ± 0.79。无论是术后即刻还是术后 1 个月的随访,VAS 评分的下降都具有显著的统计学意义。阻滞的成功率(定义为疼痛比基线减轻至少 20%)在术后即刻和术后一个月都明显较高(P < 0.001)。在接受 impar 阻滞治疗的 26 位患者中,满意度分别为:42.3% 为优、27% 为良、19.2% 为一般、11.5% 为差。结论:这项研究认可了经骶尾 "针内针 "方法来缓解尾骨痛患者的症状。研究结果显示,患者的满意度很高,大多数人都认为他们的体验非常好。
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引用次数: 0
Comparison of Ropivacaine versus Bupivacaine in Spinal-Induced Hypotension in Preeclampsia Patients: A Randomized Control Trial 罗哌卡因与布比卡因在先兆子痫患者脊髓诱发低血压中的比较:随机对照试验
Q2 Medicine Pub Date : 2024-02-29 DOI: 10.5812/aapm-142646
Morteza Hashemian, Mohsen Barouni, Zahra Honarvar, K. Alidousti, Seyed Amirabbas Mohajerani, Leila Rezaeizadeh
Background: Spinal anesthesia is considered to be the safest method of anesthesia for cesarean sections in patients with preeclampsia. Patients with preeclampsia are at an increased risk of experiencing severe hypotension following spinal anesthesia, which could have more profound and deleterious effects on both the fetus and the mother. However, bupivacaine, the most commonly used drug, can induce severe hypotension even at low doses. The purpose of this study is to minimize post-spinal hypotension in both the mother and the fetus. Objectives: To determine and compare the reduction in hypotension following spinal anesthesia in patients with preeclampsia between the ropivacaine and bupivacaine groups. Methods: In a randomized clinical trial, a total of 90 parturients with preeclampsia undergoing spinal anesthesia were enrolled and randomly divided into 2 groups: One receiving ropivacaine and the other receiving bupivacaine. The dose of spinal ropivacaine was 15 mg of a 0.5% solution, and the dose of bupivacaine was also 15 mg of a 0.5 % solution. Hemodynamic parameters, including systolic and diastolic blood pressure and heart rate, were recorded following the administration of spinal anesthesia. Pain scores and the time until the return of motor movement were also documented. Results: For statistical analysis, the t-test, Chi-square, and ANOVA tests were utilized to compare the groups. Demographic variables, including maternal age, gestational age, parity, and gravidity, were not significantly different between the 2 groups. The trend of mean systolic blood pressure (SBP) was significantly lower in the bupivacaine group compared to the ropivacaine group at all measured time points in the study (P < 0.05). The amount of ephedrine used after spinal anesthesia was significantly different at 2 and 4 minutes in the ropivacaine group compared to the bupivacaine group (P = 0.012, P = 0.025). Post-operative pain scores at 1 hour in recovery were not significantly different between the ropivacaine and bupivacaine groups (P = 0.015). The time to knee movement was also significantly shorter in the ropivacaine group compared to the bupivacaine group (P < 0.001). Conclusions: Ropivacaine reduces the incidence of hypotension in spinal anesthesia compared to bupivacaine for cesarean section in patients with preeclampsia. This is attributed to a lower occurrence of spinal-induced hypotension, improved hemodynamic control, reduced ephedrine usage, and faster patient ambulation. A future study could focus on investigating different dosages of both drugs with a larger number of participants.
背景:脊髓麻醉被认为是子痫前期患者剖宫产手术中最安全的麻醉方法。先兆子痫患者在脊髓麻醉后出现严重低血压的风险会增加,这可能会对胎儿和母亲产生更深远和有害的影响。然而,布比卡因作为最常用的药物,即使剂量较低也会诱发严重低血压。本研究的目的是尽量减少母亲和胎儿在椎管内麻醉后出现低血压。研究目的确定并比较罗哌卡因组和布比卡因组对子痫前期患者脊髓麻醉后低血压的缓解程度。方法在一项随机临床试验中,共招募了 90 名接受脊髓麻醉的子痫前期孕妇,并将其随机分为两组:一组接受罗哌卡因,另一组接受布比卡因。脊髓罗哌卡因剂量为15毫克0.5%溶液,布比卡因剂量也为15毫克0.5%溶液。脊髓麻醉后记录了血液动力学参数,包括收缩压、舒张压和心率。此外,还记录了疼痛评分和运动恢复时间。结果统计分析采用 t 检验、卡方检验和方差分析对各组进行比较。两组产妇的年龄、孕龄、胎次和胎龄等人口统计学变量无显著差异。在研究的所有测量时间点,布比卡因组的平均收缩压(SBP)都明显低于罗哌卡因组(P < 0.05)。与布比卡因组相比,罗哌卡因组在脊髓麻醉后 2 分钟和 4 分钟的麻黄碱用量明显不同(P = 0.012,P = 0.025)。术后 1 小时恢复期的疼痛评分在罗哌卡因组和布比卡因组之间无明显差异(P = 0.015)。罗哌卡因组与布比卡因组相比,膝关节活动时间也明显缩短(P < 0.001)。结论与布比卡因相比,罗哌卡因可降低子痫前期患者剖宫产脊髓麻醉中低血压的发生率。这归因于脊麻引起的低血压发生率较低、血流动力学控制得到改善、麻黄碱用量减少以及患者下床活动更快。今后的研究可重点研究两种药物的不同剂量,并增加参与人数。
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引用次数: 0
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Anesthesiology and Pain Medicine
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