N. Panse, Sumedha Mehta, K. Adate, Priyanka Gangthade
Pierre Robin sequence (PRS) with bilateral temporomandibular joint (TMJ) ankylosis is a rare and challenging case for anaesthesiologists. A 6-year-old girl with PRS along with bilateral progressive TMJ ankylosis was scheduled for gap arthroplasty. Her mouth opening was <1 finger. Securing the airway in a syndromic child with mandibular hypoplasia was challenging. We performed an asleep fibreoptic bronchoscope (FOB)-guided nasotracheal intubation while retaining spontaneous breathing. Managing a difficult paediatric airway needs expertise. We believe that with the use of FOB, difficult airways can be successfully and safely managed.
{"title":"Asleep fibreoptic bronchoscope-guided nasal intubation in a child with bilateral temporomandibular joint ankylosis","authors":"N. Panse, Sumedha Mehta, K. Adate, Priyanka Gangthade","doi":"10.4103/arwy.arwy_20_22","DOIUrl":"https://doi.org/10.4103/arwy.arwy_20_22","url":null,"abstract":"Pierre Robin sequence (PRS) with bilateral temporomandibular joint (TMJ) ankylosis is a rare and challenging case for anaesthesiologists. A 6-year-old girl with PRS along with bilateral progressive TMJ ankylosis was scheduled for gap arthroplasty. Her mouth opening was <1 finger. Securing the airway in a syndromic child with mandibular hypoplasia was challenging. We performed an asleep fibreoptic bronchoscope (FOB)-guided nasotracheal intubation while retaining spontaneous breathing. Managing a difficult paediatric airway needs expertise. We believe that with the use of FOB, difficult airways can be successfully and safely managed.","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"16 1","pages":"88 - 91"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74522238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-10DOI: 10.1183/23120541.lsc-2022.89
J. Nieto-Fontarigo, M. Hvidtfeldt, S. Cerps, S. Ramu, M. Menzel, A. Sverrild, L. Uller, C. Porsbjerg
{"title":"Budesonide reduces the bronchial epithelial response to a viral mimic in T2high asthma, and boosts anti-microbial responses in T2low asthma","authors":"J. Nieto-Fontarigo, M. Hvidtfeldt, S. Cerps, S. Ramu, M. Menzel, A. Sverrild, L. Uller, C. Porsbjerg","doi":"10.1183/23120541.lsc-2022.89","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.89","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78794052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-10DOI: 10.1183/23120541.lsc-2022.169
C. Moermans, S. Graff, Medard Laurie, Schleich Florence, V. Paulus, F. Guissard, M. Henket, R. Louis
{"title":"Effects of probiotics in uncontrolled asthma","authors":"C. Moermans, S. Graff, Medard Laurie, Schleich Florence, V. Paulus, F. Guissard, M. Henket, R. Louis","doi":"10.1183/23120541.lsc-2022.169","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.169","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73043196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-10DOI: 10.1183/23120541.lsc-2022.73
S. Graeter, Anna Schnell, Joseph Bain, Ilka Schulze, C. Vonarburg, A. Schaub
{"title":"Human plasma-derived IgG protects against respiratory pathogens in an epithelial air-liquid interface model","authors":"S. Graeter, Anna Schnell, Joseph Bain, Ilka Schulze, C. Vonarburg, A. Schaub","doi":"10.1183/23120541.lsc-2022.73","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.73","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77235073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-10DOI: 10.1183/23120541.lsc-2022.71
M. Šutovská, J. Mažerik, M. Kocmálová, S. Fraňová
{"title":"The bronchodilatory and anti-inflammatory effect of TRPV4 ion channels blocker in experimentally-induced allergic asthma.","authors":"M. Šutovská, J. Mažerik, M. Kocmálová, S. Fraňová","doi":"10.1183/23120541.lsc-2022.71","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.71","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74791173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-10DOI: 10.1183/23120541.lsc-2022.207
I. Cerqua, E. Granato, M. Riemma, A. Rossi, R. Sorrentino, G. Cirino, F. Roviezzo
{"title":"Sphingosine-1-phosphate drives sex-dimorphism in lung function","authors":"I. Cerqua, E. Granato, M. Riemma, A. Rossi, R. Sorrentino, G. Cirino, F. Roviezzo","doi":"10.1183/23120541.lsc-2022.207","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.207","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73107800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-10DOI: 10.1183/23120541.lsc-2022.28
Guilherme Dragunas, M. A. de Oliveira, W. Tavares-de-Lima, R. Gosens, C. Munhoz
{"title":"Chronic unpredictable stress exacerbates allergic airway inflammation in mice.","authors":"Guilherme Dragunas, M. A. de Oliveira, W. Tavares-de-Lima, R. Gosens, C. Munhoz","doi":"10.1183/23120541.lsc-2022.28","DOIUrl":"https://doi.org/10.1183/23120541.lsc-2022.28","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73249294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anaesthesia in a patient with seckel syndrome - Plan for contingencies","authors":"S. Rawlani, M. Nandini","doi":"10.4103/arwy.arwy_1_22","DOIUrl":"https://doi.org/10.4103/arwy.arwy_1_22","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"26 1","pages":"61 - 62"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76651797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Anand, Femitha Pournami, A. Prithvi, Anand Nandakumar, Jyothi Prabhakar, Naveen Jain
Background: Inhaled nitric oxide (iNO) has been in use for several decades now in neonates with hypoxic respiratory failure (HRF) associated with pulmonary hypertension (PH). Its requirement is uncommon, and is considered as an advanced form of support that is not widely available. Analysis of outcomes in specific settings, notably from low-middle income countries, is crucial. Objectives: To evaluate the patient profile and outcomes of neonates treated with iNO in our Level IIIB unit. Methods: This retrospective observational study describes the clinical diagnosis, management strategies and short-term outcomes of all neonates who received iNO in the years between 2013 and 2021. Details were retrieved from Electronic Medical Records and systematically analysed. Observation: Of 35 infants who received iNO during the study period, 31 (88.6%) were >34 weeks. The median and interquartile range (IQR) of oxygenation index at which iNO was started was 28 (20,33). The median (IQR) duration of iNO therapy was 48 (23,95) hours. Overall, 18 neonates (51.4%) survived till hospital discharge. Therapeutic response was best observed in infants with HRF secondary to meconium aspiration syndrome or congenital pneumonia (100% survival). Though the benefits of iNO use in congenital diaphragmatic hernia and bronchopulmonary dysplasia associated with PH are debatable, its use continues as a rescue measure. Conclusion: iNO is used in severe HRF associated with PH in neonates and can improve survival rates in select patient profiles without any major adverse outcomes.
{"title":"Inhaled nitric oxide therapy for pulmonary arterial hypertension of newborn: Eight-year experience of a level IIIB unit","authors":"V. Anand, Femitha Pournami, A. Prithvi, Anand Nandakumar, Jyothi Prabhakar, Naveen Jain","doi":"10.4103/arwy.arwy_57_21","DOIUrl":"https://doi.org/10.4103/arwy.arwy_57_21","url":null,"abstract":"Background: Inhaled nitric oxide (iNO) has been in use for several decades now in neonates with hypoxic respiratory failure (HRF) associated with pulmonary hypertension (PH). Its requirement is uncommon, and is considered as an advanced form of support that is not widely available. Analysis of outcomes in specific settings, notably from low-middle income countries, is crucial. Objectives: To evaluate the patient profile and outcomes of neonates treated with iNO in our Level IIIB unit. Methods: This retrospective observational study describes the clinical diagnosis, management strategies and short-term outcomes of all neonates who received iNO in the years between 2013 and 2021. Details were retrieved from Electronic Medical Records and systematically analysed. Observation: Of 35 infants who received iNO during the study period, 31 (88.6%) were >34 weeks. The median and interquartile range (IQR) of oxygenation index at which iNO was started was 28 (20,33). The median (IQR) duration of iNO therapy was 48 (23,95) hours. Overall, 18 neonates (51.4%) survived till hospital discharge. Therapeutic response was best observed in infants with HRF secondary to meconium aspiration syndrome or congenital pneumonia (100% survival). Though the benefits of iNO use in congenital diaphragmatic hernia and bronchopulmonary dysplasia associated with PH are debatable, its use continues as a rescue measure. Conclusion: iNO is used in severe HRF associated with PH in neonates and can improve survival rates in select patient profiles without any major adverse outcomes.","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"25 1","pages":"19 - 24"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86724679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Ramkumar, B. Mcguire, S. Myatra, M. Sorbello, F. Urdaneta, J. Divatia
{"title":"Role of airway societies in improving airway management","authors":"V. Ramkumar, B. Mcguire, S. Myatra, M. Sorbello, F. Urdaneta, J. Divatia","doi":"10.4103/arwy.arwy_6_22","DOIUrl":"https://doi.org/10.4103/arwy.arwy_6_22","url":null,"abstract":"","PeriodicalId":7848,"journal":{"name":"Airway Pharmacology and Treatment","volume":"1 1","pages":"1 - 3"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84362919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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