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Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology最新文献

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Forms and functions of cytochrome P450. 细胞色素P450的形态和功能。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1998-11-01
J J Stegeman, D R Livingstone
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引用次数: 0
Mixed function oxidase induction in Carcinus aestuarii. Field and experimental studies for the evaluation of toxicological risk due to Mediterranean contaminants. 混合功能氧化酶在口腔癌中的诱导作用。为评价地中海污染物所造成的毒理学风险进行实地和实验研究。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1998-11-01
M C Fossi, C Savelli, S Casini

The aim of this study was to test and validate the use of mixed function oxidase (MFO) induction, in the crab Carcinus aestuarii, under experimental and field studies, for the evaluation of toxicological risk due to the main contaminants in the Mediterranean. Two different experiments were performed in the laboratory in order to identify the most suitable tissues for MFO studies in this species and the most suitable and sensitive MFO responses for evaluating chemical stress due to lipophilic contaminants. In order to validate this methodology in the field, two studies were carried out in two polluted Mediterranean lagoons: a transplant experiment in Orbetello Lagoon and an in situ experiment in Venice Lagoon. The following MFO responses were investigated in hepatopancreas and gills of the crabs: ethoxyresorufin-O-deethylase (EROD) and benzo(a)pyrene hydroxylase (BPH) activities and reductase enzyme activities. The main results can be summarised as follows: midgut-gland and gills were confirmed to be useful for MFO tests; BPH activity in hepatopancreas was the most suitable and sensitive MFO response for evaluating chemical stress due to Mediterranean contaminants in laboratory and field studies; in the Orbetello Lagoon experiment, a statistically significant difference was found between sites subject to different human impact.

本研究的目的是在实验和实地研究中测试和验证混合功能氧化酶(MFO)诱导在地中海主要污染物的毒理学风险评估中的应用。在实验室中进行了两个不同的实验，以确定该物种中最适合进行MFO研究的组织，以及最适合和最敏感的MFO反应，以评估由亲脂性污染物引起的化学应激。为了在实地验证这一方法，在两个受污染的地中海泻湖进行了两项研究:在奥尔贝特洛泻湖进行移植实验，在威尼斯泻湖进行原位实验。研究了MFO在蟹肝胰腺和鳃中的反应:乙氧基间苯二酚- o -去乙基酶(EROD)、苯并(a)芘羟化酶(BPH)活性和还原酶活性。主要结果可总结如下:证实中肠腺和鳃可用于MFO试验;在实验室和实地研究中，肝胰脏BPH活性是评价地中海污染物引起的化学应激最合适和最敏感的MFO反应;在奥尔贝特洛泻湖实验中，在受到不同人类影响的地点之间发现了统计上显著的差异。
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引用次数: 0
Everything you wanted to know about sex a perspective on the first symposium on Comparative Neuroendocrinology of Vertebrate Reproduction and Growth: Molecular, Cellular and Organismal Aspects. 你想知道的关于性的一切——从脊椎动物繁殖和生长的比较神经内分泌学:分子、细胞和有机体方面的第一次研讨会的角度来看。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1998-06-01
V L Trudeau
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引用次数: 0
Bibliography of Comparative biochemistry and physiology C generated from the Current awareness in biological sciences database. 比较生物化学与生理学参考书目-从当前生物科学数据库中产生的意识。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1997-09-01
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引用次数: 0
Bibliography of Comparative Biochemistry and Physiology C generated from the Current Awareness in Biological Sciences database. 比较生物化学和生理学参考书目C从生物科学的当前意识数据库生成。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1997-06-01
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引用次数: 0
Bibliography of comparative biochemistry and physiology C generated from the current awareness in biological sciences database. 比较生物化学与生理学目录学-从目前生物科学数据库的认识中产生。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1997-05-01
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引用次数: 0
Bibliography of comparative biochemistry and physiology C generated from the Current Awareness in Biological Sciences database. 比较生物化学和生理学参考书目C从当前生物科学的认识数据库生成。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1997-01-01
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引用次数: 0
Bibliography of Comparative Biochemistry and Physiology C generated from the Current Awareness in Biological Sciences database. 比较生物化学和生理学参考书目C从生物科学的当前意识数据库生成。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1997-01-01 DOI: 10.1016/s0300-9629(96)90006-7
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引用次数: 0
Comparative biochemistry & physiology C bibliography. 比较生物化学与生理学C参考书目。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1995-05-01
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引用次数: 0
Comparative biochemistry & physiology C bibliography. 比较生物化学与生理学C参考书目。
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology
Pub Date : 1995-03-01
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引用次数: 0
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