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Transient erectile dysfunction associated with intramuscular injection of botulinum toxin type A. A型肉毒毒素肌内注射与短暂性勃起功能障碍有关。
Anastasios S Papadonikolakis, Marios D Vekris, John P Kostas, Anastasios V Korompilias, Panayotis N Soucacos

Autonomic nervous system dysfunction occurs rarely after botulinum toxin type A (BTX-A) intramuscular injections. We report a case of a 23-year-old man with spastic diplegia who had transient erectile dysfunction after intramuscular injection of BTX-A (total dosage, 300 IU, body weight 95 kg) in both hamstring muscles. Some investigators believe that the local spread of the toxin is responsible for autonomic dysfunction, while others believe that the transportation of the toxin to the spinal cord via retrograde flow or via the blood flow after entering the circulation are possible mechanisms of neurologic side effects. On the basis of our case, a retrograde axoplasmic flow to the spinal cord could probably occur because the spinal cord level of hamstring muscles is close to spinal cord levels responsible for erection control.

A型肉毒毒素(BTX-A)肌肉注射后很少发生自主神经系统功能障碍。我们报告一例23岁男性痉挛性双瘫患者,在双腿筋肌肌内注射BTX-A(总剂量300 IU,体重95 kg)后出现短暂性勃起功能障碍。一些研究者认为毒素的局部扩散是导致自主神经功能障碍的原因,而另一些研究者认为毒素通过逆行血流或进入循环后通过血流进入脊髓是神经系统副作用的可能机制。根据我们的病例,由于腘绳肌的脊髓水平接近控制勃起的脊髓水平,可能会发生向脊髓的逆行轴浆流。
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引用次数: 0
Chronic osteomyelitis associated with cat-scratch disease. 慢性骨髓炎与猫抓病有关。
Brad G Prybis, John L Eady, George S Kotchmar

Cat-scratch disease (CSD) is usually a self-limited illness, though atypical presentations of infection with Bartonella henselae can occur, including osteomyelitis, oculoglandular syndrome, and granulomatous hepatitis. We describe a 6-year-old boy who had atypical CSD osteomyelitis of the left proximal femoral metaphysis due to a cat scratch. This is the second paper to report serial serology of B henselae, and the second paper to identify plasma cells on histologic examination, compatible with chronic osteomyelitis. The diagnosis was made by clinical, serologic, and histologic examination. Sixteen cases of atypical CSD osteomyelitis have been reported in the English literature and are reviewed in this paper.

猫抓病(CSD)通常是一种自限性疾病,但也可能出现非典型的亨塞巴尔通体感染,包括骨髓炎、眼腺综合征和肉芽肿性肝炎。我们描述了一个6岁的男孩谁有不典型CSD骨髓炎的左股骨近端由于猫抓伤。这是第二篇报道henselae系列血清学的文章,也是第二篇通过组织学检查鉴定出与慢性骨髓炎相容的浆细胞的文章。经临床、血清学及组织学检查诊断。本文对英文文献报道的16例非典型CSD骨髓炎进行综述。
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引用次数: 0
Pigmented villonodular synovitis of the knee: average five-year follow-up of arthroscopic treatment. 膝关节色素绒毛结节性滑膜炎:关节镜治疗的平均5年随访。
Peter B Rauh, Jason Bernard, David M Craig

We have reviewed the results of arthroscopic treatment of pigmented villonodular synovitis (PVNS) with reference to both recurrence and to function. Between 1985 and 1995, a single surgeon treated eight patients. At an average 5-year follow-up, all patients were interviewed and had assessment of Hospital for Special Surgery (HSS) knee score for both the affected and unaffected knees. Also recorded were age, sex, and whether disease was recurrent, localized, or diffuse. Disease recurred in 4 patients, all with diffuse PVNS, and 3 of them required a further arthroscopic synovectomy at a mean of 16 months after the index procedure. All patients had good or excellent functional results. There was no significant difference between HSS knee scores for affected and unaffected knees. Arthroscopic synovectomy is a successful treatment in patients with localized PVNS of the knee and results in a knee that is functionally not different from its unaffected partner.

我们回顾了关节镜下治疗色素性绒毛结节性滑膜炎(PVNS)的结果,包括复发和功能。从1985年到1995年,一个外科医生治疗了8个病人。在平均5年的随访中,对所有患者进行访谈,并对受影响和未受影响的膝关节进行HSS (Hospital for Special Surgery)评分。还记录了年龄、性别和疾病是否复发、局部或弥漫性。4例患者复发,均为弥漫性PVNS,其中3例患者在指数手术后平均16个月需要进一步的关节镜滑膜切除术。所有患者均有良好或优异的功能效果。受影响和未受影响膝关节的HSS评分无显著差异。关节镜下滑膜切除术是一种成功的治疗膝关节局部PVNS患者的方法,其结果是膝关节与未受影响的同伴在功能上没有区别。
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引用次数: 0
Cerebral palsy: past, present, and future. 脑瘫:过去、现在和未来。
L Andrew Koman
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引用次数: 0
Fractures of the ankle: pathogenesis and treatment. 踝关节骨折:发病机制及治疗。
F C Wilson

From the foregoing, one may reduce the following principles for the management of ankle injuries: The mechanism of injury and the diagnosis, including ligamentous injury, can be made from initial radiographs. A displaced fracture of only one malleolus must be accompanied by ligamentous injury of either the deltoid or syndesmotic ligaments, or both. When there is only one break in the ring of the ankle mortise, there is no potential for significant displacement; thus, ORIF is rarely necessary. With two breaks in the ring, the potential for displacement exists, even after successful manipulation, which usually makes operative treatment a more attractive option. Closed reduction is done by reversing the direction of the injuring forces, though it is not necessary to do so in precise inverse order to their occurrences. When ORIF is used, all significant malleolar fractures should be rigidly fixed to allow early motion, which, along with delayed weight bearing, is especially beneficial when comminution of the articular surface exists. Syndesmotic fixation is usually unnecessary if the malleolar fractures can be reduced anatomically and securely fixed. The reduction, whatever technique is used, should result in full congruency of the ankle mortise and a level joint line. Trimalleolar fractures, especially when they involve more than 25% of the tibial plafond, are much more likely than bimalleolar fractures to be associated with posttraumatic arthritis.

综上所述,我们可以减少以下处理踝关节损伤的原则:损伤的机制和诊断,包括韧带损伤,可以从最初的x线片来判断。只有一个外踝的移位性骨折必须伴有三角韧带或联合韧带的韧带损伤,或两者兼有。当踝关节榫环只有一个断裂时,没有明显位移的可能;因此,很少需要ORIF。由于环上有两次断裂,即使在成功操作后也存在移位的可能性,这通常使手术治疗成为更有吸引力的选择。闭合复位是通过逆转损伤力的方向来完成的,尽管没有必要按照它们出现的精确逆顺序这样做。当使用ORIF时,所有重要的踝部骨折都应严格固定,以便早期活动,这与延迟负重一起,在关节面存在粉碎性时尤其有益。如果踝骨骨折可以解剖复位并安全固定,通常不需要骨联合固定。复位,无论采用何种技术,都应使踝关节榫完全一致,关节线水平。三踝骨折,特别是当它们累及超过25%的胫骨平台时,比双踝骨折更容易与创伤后关节炎相关。
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引用次数: 0
Iliac crest autogenous bone grafting: donor site complications. 髂骨自体骨移植:供区并发症。
J G Seiler, J Johnson

Autogenous bone grafting is often done in orthopaedic surgery for a variety of conditions. The iliac crest is currently the most common donor site for obtaining autogenous bone graft. We searched the literature to summarize reported complications related to the donation of autogenous bone from the iliac crest. Our review revealed reports of arterial injury, ureteral injury, herniation, chronic pain, nerve injury, infection, fracture, pelvic instability, cosmetic defects, hematoma, and tumor transplantation. Currently, autogenous bone grafting is a necessary part of the treatment of various orthopaedic conditions. Obtaining bone from the iliac crest can be associated with significant morbidity. As bone grafting technology emerges, the known complications of the current standard should be weighed against the risk of alternate therapies.

自体骨移植常用于各种情况的骨科手术。髂骨是目前获得自体骨移植最常见的供体部位。我们检索了文献,总结了与髂骨自体骨捐献相关的并发症报道。我们回顾了动脉损伤、输尿管损伤、疝、慢性疼痛、神经损伤、感染、骨折、骨盆不稳定、美容缺陷、血肿和肿瘤移植的报道。目前,自体骨移植是治疗各种骨科疾病的必要组成部分。从髂骨取骨可引起显著的发病率。随着植骨技术的出现,现有标准的已知并发症应该与替代疗法的风险进行权衡。
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引用次数: 0
Transesophageal echocardiography in quantification of emboli during femoral nailing: reamed versus unreamed techniques. 经食管超声心动图在股内钉术中量化栓塞:扩孔与未扩孔技术。
R E Coles, F M Clements, J W Lardenoye, G V Wermeskerken, L A Hey, J A Nunley, L S Levin, A W Pearsall

We quantified the embolic load to the lungs created with two different techniques of femoral nailing. Eleven patients with 12 traumatic femur fractures were randomized to reamed (7 fractures) and unreamed (5 fractures) groups. Intramedullary nailing was with the AO/ASIF* universal reamed or unreamed nail. Transesophageal echocardiography (TEE) was used to evaluate the quantity and quality of emboli generated by nailing. Data were analyzed using software that digitized the TEE images and quantified the area of embolic particles in each frame. The duration of each level of embolic phenomena (zero, moderate, severe) was used to determine total embolic load with various steps (fracture manipulation, proximal portal opening, reaming, and nail passage). Manual grading of emboli correlated highly with software quantification. Our data confirm the presence and similarity of emboli generation with both methods of intramedullary nailing. Unreamed nails do not protect the patient from pulmonary embolization of marrow contents.

我们量化了两种不同的股内钉技术对肺部造成的栓塞负荷。11例12例外伤性股骨骨折患者随机分为扩孔组(7例)和未扩孔组(5例)。髓内钉采用AO/ASIF*通用扩孔或未扩孔钉。采用经食管超声心动图(TEE)评价钉入后栓子的数量和质量。使用软件对TEE图像进行数字化分析,并对每帧中的栓塞颗粒面积进行量化。每个级别的栓塞现象(零,中等,严重)的持续时间被用来确定不同步骤(骨折操作,近端门静脉打开,扩孔和钉子通道)的总栓塞负荷。栓子的人工分级与软件量化高度相关。我们的数据证实了两种髓内钉方法产生栓子的存在和相似性。未扩孔的指甲不能保护患者免于骨髓内容物的肺栓塞。
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引用次数: 0
Digital flexor sheath: repair and reconstruction of the annular pulleys and membranous sheath. 指屈肌鞘:环形滑轮和膜鞘的修复和重建。
J G Seiler, F J Leversedge

Rupture or transection of the digital pulley may necessitate repair or reconstruction to treat symptomatic flexor tendon bowstringing. When reconstruction is necessary, intrasynovial tendon grafts may provide superior gliding characteristics when compared with traditional extrasynovial tendon grafts. Lacerations of the membranous portion of the digital sheath and of noncritical annular pulleys usually do not require operative repair.

手指滑轮断裂或横断可能需要修复或重建治疗症状性屈肌腱弓弦。当需要重建时,与传统的滑膜外肌腱移植物相比,滑膜内肌腱移植物可以提供更好的滑动特性。指鞘的膜性部分和非临界环形滑带的撕裂通常不需要手术修复。
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引用次数: 0
Arthroscopy of the elbow for synovial chondromatosis. 肘关节镜治疗滑膜软骨瘤病。
J W Byrd

Two cases of arthroscopic removal of multiple loose bodies are presented. Successful results were achieved, and patients had 4-year follow-up. Both cases involved classic manifestations of synovial chondromatosis. Associated degenerative changes were present in one case; histologic examination could not confirm synovial origin of the disease. Arthroscopy for removal of symptomatic loose bodies is an excellent choice as exemplified by these two cases. Care should be taken to review histologic findings, which may help in understanding the natural history of this type of process.

本文报道两例关节镜下多体松脱术。获得了成功的结果,并对患者进行了4年的随访。这两个病例都有滑膜软骨瘤病的典型表现。1例出现相关退行性改变;组织学检查不能确定疾病的滑膜起源。关节镜切除有症状的松脱体是一个很好的选择,这两个病例就是例证。应注意回顾组织学发现,这可能有助于理解这种类型过程的自然历史。
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引用次数: 0
Past, present, and future of the Clinical Orthopaedic Society. 临床骨科学会的过去、现在和未来。
J C DeFiore
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Journal of the Southern Orthopaedic Association
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