J Prakash, A Gupta, V Malhotra, O Kumar, P K Srivastava
A total of 638 patients with acute renal failure (ARF) of diverse etiology were studied over a period of 9 years (July 1985-Dec, 1994) of which 96 (15%) patients were classified as elderly ARF with mean age of 72.5 years. Medical causes accounted for 80% of geriatric ARF while 20% patients, had ARF of surgical origin. Decreased renal perfusion resulting from gastroenteritis was the predominant (52.8%) cause of ARF in the medical group. Nephrotoxic ARF and ARF due to F. malaria were seen in 10 and 7 patients respectively. Obstructive uropathy was observed in 12 patients in surgical group and in remaining 8 patients ARF developed following various surgical procedures. ARF in association with multiorgan failure was not observed in our study. Mortality was seen in 24 patients (25%). The causes of mortality were GI bleed (6), peripheral circulatory failure (5), hyperkalemia (4) and sepsis (4). Thus medical ARF remains the major cause of acute renal failure in elderly patients in our study in contrast to ARF associated with multiorgan failure and surgery in developed countries.
{"title":"Acute renal failure in the elderly: a demographic and clinical study of patients in eastern India.","authors":"J Prakash, A Gupta, V Malhotra, O Kumar, P K Srivastava","doi":"10.1023/a:1008268525309","DOIUrl":"https://doi.org/10.1023/a:1008268525309","url":null,"abstract":"<p><p>A total of 638 patients with acute renal failure (ARF) of diverse etiology were studied over a period of 9 years (July 1985-Dec, 1994) of which 96 (15%) patients were classified as elderly ARF with mean age of 72.5 years. Medical causes accounted for 80% of geriatric ARF while 20% patients, had ARF of surgical origin. Decreased renal perfusion resulting from gastroenteritis was the predominant (52.8%) cause of ARF in the medical group. Nephrotoxic ARF and ARF due to F. malaria were seen in 10 and 7 patients respectively. Obstructive uropathy was observed in 12 patients in surgical group and in remaining 8 patients ARF developed following various surgical procedures. ARF in association with multiorgan failure was not observed in our study. Mortality was seen in 24 patients (25%). The causes of mortality were GI bleed (6), peripheral circulatory failure (5), hyperkalemia (4) and sepsis (4). Thus medical ARF remains the major cause of acute renal failure in elderly patients in our study in contrast to ARF associated with multiorgan failure and surgery in developed countries.</p>","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 2","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008268525309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20351286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elderly patients may exhibit changes in plasma hormone levels, as well as thirst disorders. Two groups of elderly hemodialysis patients were evaluated to determine if excessive interdialytic weight gain was related to differences in postdialysis plasma osmolality or postdialysis measurement of plasma renin activity, or plasma levels of angiotensin II (a dipsogenic hormone), aldosterone, and vasopressin. Patients mean age was 77.0 +/- 8.8 years and patients were divided into groups, I and II, with less than or greater than 2 kg interdialytic weight gain. Postdialysis plasma osmolality was similar in both groups of patients (309.3 +/- 2.3 vs. 309.6 +/- 2.4 mOsm/Kg, p = 0.8) and postdialysis AVP levels also were no different (2.7 +/- 0.6 vs. 2.1 +/- 0.2 pg/mL, p = 0.3). There was also no statistical difference between postdialysis angiotensin II and aldosterone levels in either group of patients. Plasma renin activity (PRA) was also not different in either group (2.3 +/- 1.1 vs. 0.43 +/- 0.1 ng/mL/hr, p = 0.1), but group I patients, with less than 2 kg weight gain, tended to exhibit higher PRA values perhaps reflecting proximity to their dry weight postdialysis. Since excessive fluid intake did not appear to relate to plasma osmolality and hormone levels studied, it might be suggested that excessive drinking could be due to excessive sodium intake associated with personal dietary habits or perhaps other as yet unmeasured factors.
老年患者可能表现出血浆激素水平的变化,以及口渴障碍。对两组老年血液透析患者进行评估,以确定过度的透析间期体重增加是否与透析后血浆渗透压或透析后血浆肾素活性测量或血浆血管紧张素II(一种糖尿病激素)、醛固酮和血管加压素水平的差异有关。患者的平均年龄为77.0±8.8岁,患者分为I组和II组,透析间期体重增加小于或大于2 kg。两组患者的透析后血浆渗透压相似(309.3 +/- 2.3 vs 309.6 +/- 2.4 mOsm/Kg, p = 0.8),透析后AVP水平也无差异(2.7 +/- 0.6 vs 2.1 +/- 0.2 pg/mL, p = 0.3)。两组患者透析后血管紧张素II和醛固酮水平也无统计学差异。血浆肾素活性(PRA)在两组中也没有差异(2.3 +/- 1.1 vs. 0.43 +/- 0.1 ng/mL/hr, p = 0.1),但体重增加小于2 kg的I组患者往往表现出更高的PRA值,这可能反映了透析后他们的干重接近。由于过量的液体摄入似乎与所研究的血浆渗透压和激素水平无关,因此可能建议过量饮酒可能是由于与个人饮食习惯或其他尚未测量的因素相关的过量钠摄入所致。
{"title":"Evaluation of plasma osmolality and hormone responses in elderly chronic hemodialysis patients with excessive interdialytic weight gain.","authors":"R Samuel-Variath, R Chan, M F Michelis","doi":"10.1023/a:1008294601458","DOIUrl":"https://doi.org/10.1023/a:1008294601458","url":null,"abstract":"<p><p>Elderly patients may exhibit changes in plasma hormone levels, as well as thirst disorders. Two groups of elderly hemodialysis patients were evaluated to determine if excessive interdialytic weight gain was related to differences in postdialysis plasma osmolality or postdialysis measurement of plasma renin activity, or plasma levels of angiotensin II (a dipsogenic hormone), aldosterone, and vasopressin. Patients mean age was 77.0 +/- 8.8 years and patients were divided into groups, I and II, with less than or greater than 2 kg interdialytic weight gain. Postdialysis plasma osmolality was similar in both groups of patients (309.3 +/- 2.3 vs. 309.6 +/- 2.4 mOsm/Kg, p = 0.8) and postdialysis AVP levels also were no different (2.7 +/- 0.6 vs. 2.1 +/- 0.2 pg/mL, p = 0.3). There was also no statistical difference between postdialysis angiotensin II and aldosterone levels in either group of patients. Plasma renin activity (PRA) was also not different in either group (2.3 +/- 1.1 vs. 0.43 +/- 0.1 ng/mL/hr, p = 0.1), but group I patients, with less than 2 kg weight gain, tended to exhibit higher PRA values perhaps reflecting proximity to their dry weight postdialysis. Since excessive fluid intake did not appear to relate to plasma osmolality and hormone levels studied, it might be suggested that excessive drinking could be due to excessive sodium intake associated with personal dietary habits or perhaps other as yet unmeasured factors.</p>","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"7 3","pages":"131-5"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1008294601458","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20417442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harry G. Preuss, S. Jarrell, N. Bushehri, Victor Onyejiaka, N. Mirdamadi-Zonozi
{"title":"Nutrients and trace elements as they affect blood pressure in the elderly","authors":"Harry G. Preuss, S. Jarrell, N. Bushehri, Victor Onyejiaka, N. Mirdamadi-Zonozi","doi":"10.1007/BF00249633","DOIUrl":"https://doi.org/10.1007/BF00249633","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"169-179"},"PeriodicalIF":0.0,"publicationDate":"1997-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00249633","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51090249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Renal sodium transport in healthy elderly and elderly with systolic hypertension","authors":"Huamin Wang, Ming-Zi Zhang, Haiyan Wang","doi":"10.1007/BF00451972","DOIUrl":"https://doi.org/10.1007/BF00451972","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"13-19"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451972","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51317050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peritoneal dialysis in the nineth decade of life experience in a single center","authors":"A. Vecchi, M. Maccario, C. Ponticelli","doi":"10.1007/BF00451110","DOIUrl":"https://doi.org/10.1007/BF00451110","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"75-80"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51314790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rehabilitation of the elderly patient on dialysis","authors":"N. Kutner","doi":"10.1007/BF00451111","DOIUrl":"https://doi.org/10.1007/BF00451111","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"81-88"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51314798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Hansen, M. Benjamin, R. G. Appel, T. Craven, R. Dean
{"title":"Renovascular hypertension in the elderly: Results of surgical management","authors":"K. Hansen, M. Benjamin, R. G. Appel, T. Craven, R. Dean","doi":"10.1007/BF00451971","DOIUrl":"https://doi.org/10.1007/BF00451971","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"3-11"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451971","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51317038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lisinopril has no natriuretic effect in elderly: A study of the single-dose response in aged vs young individuals","authors":"D. Chevet, J. Mallié, C. Jeandel","doi":"10.1007/BF00451109","DOIUrl":"https://doi.org/10.1007/BF00451109","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"69-74"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51314779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical physiology — pharmacology: multifactorial hypocalcemia in an elderly patient with myeloproliferative disorder","authors":"D. Maggio, A. Cherubim, U. Senin, D. Lowenthal","doi":"10.1007/BF00451115","DOIUrl":"https://doi.org/10.1007/BF00451115","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"113-117"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51314840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Jessup, D. Lowenthal, M. Pollock, K. Smyth, L. Williams, J. Ruiz, M. Fagien, L. Garzarella
{"title":"Exercise training in older men and women: Effects on cardiovascular and renal function","authors":"J. Jessup, D. Lowenthal, M. Pollock, K. Smyth, L. Williams, J. Ruiz, M. Fagien, L. Garzarella","doi":"10.1007/BF00451974","DOIUrl":"https://doi.org/10.1007/BF00451974","url":null,"abstract":"","PeriodicalId":79490,"journal":{"name":"Geriatric nephrology and urology","volume":"6 1","pages":"27-34"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF00451974","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51317088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}