Pub Date : 2019-01-01DOI: 10.31058/J.AC.2019.21002
A. Heidari
{"title":"Debromoaplysiatoxin Time�CResolved Absorption and Resonance FT�CIR and Raman Biospectroscopy and Density Functional Theory (DFT) Investigation of Vibronic�CMode Coupling Structure in Vibrational Spectra Analysis","authors":"A. Heidari","doi":"10.31058/J.AC.2019.21002","DOIUrl":"https://doi.org/10.31058/J.AC.2019.21002","url":null,"abstract":"","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77521825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.31058/j.ac.2019.21001
Md. Saddam Hossain
{"title":"A Short Review on Antimicrobial Activity Study on Transition Metal Complexes of Ni Incorporating Schiff Bases","authors":"Md. Saddam Hossain","doi":"10.31058/j.ac.2019.21001","DOIUrl":"https://doi.org/10.31058/j.ac.2019.21001","url":null,"abstract":"","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74012363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.31058/J.AC.2018.11002
I. M. Iloamaeke
Extraction of the leaves of Sarcocephalus latifolius was done using acetone, methanol, diethylether, petroleum ether, water and ethanol as solvent to analyze its phytochemical constituents followed by the quantitative analysis and antimicrobial property. Phytochemical analysis indicated the presence of alkaloids (5.22%) in diethylether, petroleum ether and water extracts, saponins (18.2%) in methanol and water extracts, but trace amount in acetone, petroleum ether and ethanol extracts, tannins (0.63%) in water and ethanol extracts, glycosides (0.72%) in acetone, diethyl ether, ethanol, water and methanol extracts while steroids and flavonoids were absent. Antimicrobial susceptibility test of water and methanol extract was done using the agar well diffusion method against clinical isolates of gram positive bacteria (and staphylococcus aureus) and gram negative bacteria (Escherichia coli and Salmonella typhi). The result of water extract showed higher inhibition potency than the methanol extract when compared with the positive control Ciprofloxacin. Heavy metal analysis was also conducted, the result indicated absence of chromium, lead, and arsenic, presence of zinc(0.18ppm), nickel(7.69ppm), manganese(2.21ppm), iron(1.36ppm),) and copper(0.1ppm). All were within W.H.O acceptable limit except nickel. This result concludes that the leaves of Sarcocephalus latifolius is medicinal as speculated by the orthodox medicine, but the heavy metals constituents of the plant should also be considered to avoid taking contaminated extract as medicine.
{"title":"Phytochemical, Antimicrobial and Heavy Metals Analyses of Sarcocephalus Latifolius Leave Extract","authors":"I. M. Iloamaeke","doi":"10.31058/J.AC.2018.11002","DOIUrl":"https://doi.org/10.31058/J.AC.2018.11002","url":null,"abstract":"Extraction of the leaves of Sarcocephalus latifolius was done using acetone, methanol, diethylether, petroleum ether, water and ethanol as solvent to analyze its phytochemical constituents followed by the quantitative analysis and antimicrobial property. Phytochemical analysis indicated the presence of alkaloids (5.22%) in diethylether, petroleum ether and water extracts, saponins (18.2%) in methanol and water extracts, but trace amount in acetone, petroleum ether and ethanol extracts, tannins (0.63%) in water and ethanol extracts, glycosides (0.72%) in acetone, diethyl ether, ethanol, water and methanol extracts while steroids and flavonoids were absent. Antimicrobial susceptibility test of water and methanol extract was done using the agar well diffusion method against clinical isolates of gram positive bacteria (and staphylococcus aureus) and gram negative bacteria (Escherichia coli and Salmonella typhi). The result of water extract showed higher inhibition potency than the methanol extract when compared with the positive control Ciprofloxacin. Heavy metal analysis was also conducted, the result indicated absence of chromium, lead, and arsenic, presence of zinc(0.18ppm), nickel(7.69ppm), manganese(2.21ppm), iron(1.36ppm),) and copper(0.1ppm). All were within W.H.O acceptable limit except nickel. This result concludes that the leaves of Sarcocephalus latifolius is medicinal as speculated by the orthodox medicine, but the heavy metals constituents of the plant should also be considered to avoid taking contaminated extract as medicine.","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"12 20 1","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73467451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.31058/J.AC.2018.11001
E. L. Ayuk, Boniface I Eze, A. N. Njokunwogbu, Samuel B. Aronimo
Phenothiazine and its derivatives are very important compounds that have many biological and industrial applications. Azo-compounds on the other hand have also been identified to possess good dyeing and biological properties as well. This work is focused on the synthesis of new linear phenothiazine azo-dye compounds via diazotization reaction as well as the determination of their biological activity against some microogrganisms. The above was achieved by the condensation reaction of 3- nitoaniline and phenol in presence of potassium hydroxide and DMF (solvent) to furnished 3-nitrodiphenylamine. Sulphonation of this compound in presence of molecular iodine gave 4-nitro-[10H]-phenothiazine. The conversion of nitro group in 4-nitro-[10H]-phenothiazine to an amino group was achieved by treating it with dilute hydrochloric acid and iron (III) chloride. The amino compound formed, (4-amino-[10H]-phenothiazine) was thereafter converted to an unstable diazonium ion in the presence of sodium nitrite and concentrated hydrochloric. The ion formed above was immediately coupled with the following compounds; 3-nitroaniline, 4-nitroaniline and phenol respectively to furnish four new azophenothiazine compounds namely; 4-azo-(4-amino-2-nitroanilino)-[10H]-phenothiazine, 4-azo-(2-amino-5-nitroanilino)-[10H]- phenothiazine and 4-azo-(4-hydroxyphenyl)-[10H]-phenothiazine with good percentage yields. The synthesized compounds were tested for activity against some microorganisms and they showed some level of inhibition.
{"title":"Functionalization and Antimicrobial Evaluation of New Linear Azo-Phenothiazine Derivatives","authors":"E. L. Ayuk, Boniface I Eze, A. N. Njokunwogbu, Samuel B. Aronimo","doi":"10.31058/J.AC.2018.11001","DOIUrl":"https://doi.org/10.31058/J.AC.2018.11001","url":null,"abstract":"Phenothiazine and its derivatives are very important compounds that have many biological and industrial applications. Azo-compounds on the other hand have also been identified to possess good dyeing and biological properties as well. This work is focused on the synthesis of new linear phenothiazine azo-dye compounds via diazotization reaction as well as the determination of their biological activity against some microogrganisms. The above was achieved by the condensation reaction of 3- nitoaniline and phenol in presence of potassium hydroxide and DMF (solvent) to furnished 3-nitrodiphenylamine. Sulphonation of this compound in presence of molecular iodine gave 4-nitro-[10H]-phenothiazine. The conversion of nitro group in 4-nitro-[10H]-phenothiazine to an amino group was achieved by treating it with dilute hydrochloric acid and iron (III) chloride. The amino compound formed, (4-amino-[10H]-phenothiazine) was thereafter converted to an unstable diazonium ion in the presence of sodium nitrite and concentrated hydrochloric. The ion formed above was immediately coupled with the following compounds; 3-nitroaniline, 4-nitroaniline and phenol respectively to furnish four new azophenothiazine compounds namely; 4-azo-(4-amino-2-nitroanilino)-[10H]-phenothiazine, 4-azo-(2-amino-5-nitroanilino)-[10H]- phenothiazine and 4-azo-(4-hydroxyphenyl)-[10H]-phenothiazine with good percentage yields. The synthesized compounds were tested for activity against some microorganisms and they showed some level of inhibition.","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"191 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72810810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2013-01-01DOI: 10.1007/978-1-4614-4262-2
O. V. Roussak, H. D. Gesser
{"title":"Applied Chemistry: A Textbook for Engineers and Technologists","authors":"O. V. Roussak, H. D. Gesser","doi":"10.1007/978-1-4614-4262-2","DOIUrl":"https://doi.org/10.1007/978-1-4614-4262-2","url":null,"abstract":"","PeriodicalId":7954,"journal":{"name":"Applied Chemistry","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73038731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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