Clinical laser monthly最新文献_第2页

LAUP found successful for sleep apnea, snoring. LAUP成功治疗了睡眠呼吸暂停，打鼾。

Clinical laser monthly

Pub Date : 1994-03-01

J Dibler

引用次数: 0

Functional Aqualaser sinuscopy for nasal polyposis. 鼻息肉病的功能性超声鼻窦镜检查。

Clinical laser monthly

Pub Date : 1994-02-01

D M Schuman, R Pineyro

引用次数: 0

Use of Nd:YAG for excision of breast lesions promising. 使用Nd:YAG切除乳腺病变有希望。

Clinical laser monthly

Pub Date : 1994-01-01

C J Daly

引用次数: 0

Excimer angioplasty: multicenter trials showing excellent results. 准分子血管成形术:多中心试验显示良好的结果。

Clinical laser monthly

Pub Date : 1993-11-01

F Litvack, N Eigler

引用次数: 0

Q-switched ruby laser provides effective treatment for tattoos. 调q红宝石激光提供有效的治疗纹身。

Clinical laser monthly

Pub Date : 1993-11-01

R Ashinoff

引用次数: 0

Pulsed dye laser gives hope to scar patients. 脉冲染料激光给疤痕患者带来希望。

Clinical laser monthly

Pub Date : 1993-10-01

T Alster

引用次数: 0

Green light photodynamic therapy in the human bladder. 绿色光动力疗法在人类膀胱中的应用。

Clinical laser monthly

Pub Date : 1993-10-01 DOI: 10.1089/CLM.1993.11.247

U. Nseyo, D. Merrill, S. Lundahl

We conducted this pilot clinical study to investigate the safety, primarily acute toxicity, of green light (514.5 nm) whole bladder photodynamic therapy (PDT) in human bladders with transitional cell carcinoma. We enrolled five patients who were scheduled to undergo radical cystectomy and urinary diversion for locally muscle invasive bladder cancer. Four patients received intravenous injection of Photofrin at 1 mg/kg, while one patient received no drug, 48 hr before undergoing green light whole bladder photoactivation with light doses of 20-60 J/cm 2. Each patient underwent radical cystectomy on day 7 following light treatment. Post-PDT evaluation included daily monitoring of voiding symptoms, cystometric measurements of bladder capacity, and gross and histopathologic examination of the excised bladders. Our results show that the intensity of acute bladder irritation and acute post-PDT loss in bladder volume depended on the light dose and extent of bladder tumor with the associated inflammation. There was no transmural bladder injury and no treatment related morbidity. These data on acute toxicity suggest that green light whole bladder PDT treatment with 1 mg/kg of Photofrin and 20-40 J/cm 2 of laser power is safe.

我们进行了这项实验性临床研究，以研究绿光(514.5 nm)全膀胱光动力治疗(PDT)对人类膀胱移行细胞癌的安全性，主要是急性毒性。我们招募了5例因局部肌肉浸润性膀胱癌而计划行根治性膀胱切除术和尿转移的患者。4例患者静脉注射Photofrin，剂量为1 mg/kg, 1例患者不给药，48小时后进行绿光全膀胱光激活，光剂量为20-60 J/ cm2。每位患者在轻度治疗后的第7天接受根治性膀胱切除术。pdt后的评估包括每日监测排尿症状、膀胱容量的膀胱计量测量以及切除膀胱的大体和组织病理学检查。我们的研究结果表明，急性膀胱刺激的强度和急性pdt后膀胱体积的损失取决于光剂量和膀胱肿瘤的范围以及相关的炎症。无经壁膀胱损伤，无治疗相关并发症。这些急性毒性数据表明，以1 mg/kg的Photofrin和20-40 J/ cm2的激光功率进行绿光全膀胱PDT治疗是安全的。

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引用次数: 13

Holmium thermal sclerostomy: successful approach to glaucoma. 钬热巩膜造口术:青光眼的成功入路。

Clinical laser monthly

Pub Date : 1993-10-01

C Channon

引用次数: 0

Green light photodynamic therapy in the human bladder. 绿色光动力疗法在人类膀胱中的应用。

Clinical laser monthly

Pub Date : 1993-10-01

U O Nseyo, D C Merrill, S L Lundahl

We conducted this pilot clinical study to investigate the safety, primarily acute toxicity, of green light (514.5 nm) whole bladder photodynamic therapy (PDT) in human bladders with transitional cell carcinoma. We enrolled five patients who were scheduled to undergo radical cystectomy and urinary diversion for locally muscle invasive bladder cancer. Four patients received intravenous injection of Photofrin at 1 mg/kg, while one patient received no drug, 48 hr before undergoing green light whole bladder photoactivation with light doses of 20-60 J/cm 2. Each patient underwent radical cystectomy on day 7 following light treatment. Post-PDT evaluation included daily monitoring of voiding symptoms, cystometric measurements of bladder capacity, and gross and histopathologic examination of the excised bladders. Our results show that the intensity of acute bladder irritation and acute post-PDT loss in bladder volume depended on the light dose and extent of bladder tumor with the associated inflammation. There was no transmural bladder injury and no treatment related morbidity. These data on acute toxicity suggest that green light whole bladder PDT treatment with 1 mg/kg of Photofrin and 20-40 J/cm 2 of laser power is safe.

我们进行了这项实验性临床研究，以研究绿光(514.5 nm)全膀胱光动力治疗(PDT)对人类膀胱移行细胞癌的安全性，主要是急性毒性。我们招募了5例因局部肌肉浸润性膀胱癌而计划行根治性膀胱切除术和尿转移的患者。4例患者静脉注射Photofrin，剂量为1 mg/kg, 1例患者不给药，48小时后进行绿光全膀胱光激活，光剂量为20-60 J/ cm2。每位患者在轻度治疗后的第7天接受根治性膀胱切除术。pdt后的评估包括每日监测排尿症状、膀胱容量的膀胱计量测量以及切除膀胱的大体和组织病理学检查。我们的研究结果表明，急性膀胱刺激的强度和急性pdt后膀胱体积的损失取决于光剂量和膀胱肿瘤的范围以及相关的炎症。无经壁膀胱损伤，无治疗相关并发症。这些急性毒性数据表明，以1 mg/kg的Photofrin和20-40 J/ cm2的激光功率进行绿光全膀胱PDT治疗是安全的。

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引用次数: 0

Back pain sufferers see quick recovery with laser disc surgery. 腰酸背痛患者可以通过激光椎间盘手术快速康复。

Clinical laser monthly

Pub Date : 1993-09-01

S Jacobson

引用次数: 0