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Roles of TRPV4 and piezo channels in stretch-evoked Ca2+ response in chondrocytes. TRPV4和压电通道在软骨细胞拉伸诱发的Ca2+反应中的作用
IF 3.2 Pub Date : 2020-02-01 Epub Date: 2019-12-02 DOI: 10.1177/1535370219892601
Genlai Du, Li Li, Xinwang Zhang, Jianbing Liu, Jianqing Hao, Jianjun Zhu, Hao Wu, Weiyi Chen, Quanyou Zhang
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引用次数: 0
Helen Margaret Wallis, 1924–1995 海伦·玛格丽特·沃利斯,1924-1995
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引用次数: 0
I am not a man: Maybe this makes things different 我不是男人:也许这让事情有所不同
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引用次数: 0
Bayesian population reconstruction of female populations for less developed and more developed countries. 欠发达国家和较发达国家女性人口的贝叶斯人口重建。
IF 0.8 Pub Date : 2016-01-01 Epub Date: 2016-02-23 DOI: 10.1080/00324728.2016.1139164
Mark C Wheldon, Adrian E Raftery, Samuel J Clark, Patrick Gerland

We show that Bayesian population reconstruction, a recent method for estimating past populations by age, works for data of widely varying quality. Bayesian reconstruction simultaneously estimates age-specific population counts, fertility rates, mortality rates, and net international migration flows from fragmentary data, while formally accounting for measurement error. As inputs, Bayesian reconstruction uses initial bias-reduced estimates of standard demographic variables. We reconstruct the female populations of three countries: Laos, a country with little vital registration data where population estimation depends largely on surveys; Sri Lanka, a country with some vital registration data; and New Zealand, a country with a highly developed statistical system and good quality vital registration data. In addition, we extend the method to countries without censuses at regular intervals. We also use it to assess the consistency of results between model life tables and available census data, and hence to compare different model life table systems.

我们的研究表明,贝叶斯人口重建法是一种按年龄估算过去人口的最新方法,它适用于质量参差不齐的数据。贝叶斯重构法可同时从零散数据中估算特定年龄的人口数量、生育率、死亡率和国际移民净流量,同时正式考虑测量误差。作为输入,贝叶斯重构使用标准人口变量的初始偏差缩小估计值。我们重建了三个国家的女性人口:老挝是一个缺乏人口动态登记数据的国家,其人口估计主要依赖于调查;斯里兰卡是一个拥有一些人口动态登记数据的国家;新西兰是一个拥有高度发达的统计系统和高质量人口动态登记数据的国家。此外,我们还将该方法推广到没有定期进行人口普查的国家。我们还用它来评估生命表模型与现有人口普查数据之间结果的一致性,从而对不同的生命表模型系统进行比较。
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引用次数: 0
Annals, Volume 105 Index 年鉴,第105卷索引
Pub Date : 2015-11-02 DOI: 10.1080/00045608.2015.1096111
D. Lambert, M. Solem, Sirpa Tani
Achieving Human Potential Through Geography Education: A Capabilities Approach to Curriculum Making in Schools, David Lambert, Michael Solem, and Sirpa Tani 4:723 Agro-Ecology and Food Sovereignty Movements in Chile: Sociospatial Practices for Alternative Peasant Futures, Beatriz Cid Aguayo and Alex Latta 2:397 Aguayo, Beatriz Cid, and Alex Latta, Agro-Ecology and Food Sovereignty Movements in Chile: Sociospatial Practices for Alternative Peasant Futures 2:397 Alter-Childhoods: Biopolitics and Childhoods in Alternative Education Spaces, Peter Kraftl 1:219 An, Li, Ming-Hsiang Tsou, Stephen E. S. Crook, Yongwan Chun, Brian Spitzberg, J. Mark Gawron, and Dipak K. Gupta, Space–Time Analysis: Concepts, Quantitative Methods, and Future Directions 5:891 Anderson, Eva, see Clark, William A. V. Andrucki, Max J., and Jen Dickinson, Rethinking Centers and Margins in Geography: Bodies, Life Course, and the Performance of Transnational Space 1:203 Another Place Is Possible? Labor Geography, Spatial Dispossession, and Gendered Resistance in Central Appalachia, Barbara Ellen Smith 3:567 The Art of Socioecological Transformation, Harriet Hawkins, Sallie A. Marston, Mrill Ingram, and Elizabeth Straughan 2:331 Atchison, Christopher L., see, Hawthorne, Timothy L.
《通过地理教育实现人类潜能:学校课程设置的能力方法》,David Lambert, Michael Solem和Sirpa Tani,《智利的农业生态和粮食主权运动:替代农民未来的社会空间实践》,Beatriz Cid Aguayo和Alex Latta,《智利的农业生态和粮食主权运动:替代农民未来的社会空间实践》,2:397安,李明祥,邹明祥,斯蒂芬E. S.克鲁克,春永万,Brian Spitzberg, J. Mark Gawron, Dipak K. Gupta,时空分析:概念、定量方法和未来方向:891安德森,Eva,参见Clark, William A. V. Andrucki, Max J., Jen Dickinson,地理学中的中心与边缘:身体、生命历程和跨国空间的表现:203另一个地方是可能的?《社会生态转型的艺术》,Harriet Hawkins, Sallie A. Marston, Mrill Ingram, and Elizabeth Straughan, 2:331 Atchison, Christopher L., see, Hawthorne, Timothy L.。
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引用次数: 0
Manuscript Reviewers 手稿评论者
Pub Date : 2015-11-02 DOI: 10.1080/00045608.2015.1076310
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引用次数: 0
Invention in the United States City System 美国城市制度的发明
Pub Date : 2015-10-16 DOI: 10.1080/00045608.2015.1074497
Breandán Ó hUallacháin, K. Kane, S. Kenyon
This article draws on several empirical regularities underlying central place theory (CPT) to enhance understanding of the uneven distribution of invention in the U.S. city system, especially the immense array of specializations that comprise national technological advance. CPT depicts city systems as collections of places in which functions expand in number as city size increases. Small cities have few functions and large cities many. A long-term hierarchical system is successively inclusive if large cities have all of the functions of smaller cities and some additional ones. The functions investigated here are 399 patent classes distributed across 366 U.S. metropolitan areas in the period from 2000 to 2011. Evidence is strong that patent classes with large numbers of awards are widely spread across the city system. This leads to the average sizes of places active in generating patents in the robust classes to be significantly smaller compared with the average sizes of areas that generate patents in unusual classes. Small cities are tied to national technological advance through the generation of patents in the most active and ubiquitous inventive specialties. Inventors in large cities are more likely to invent in unusual domains. Bigger areas are significantly more diversified compared with smaller ones. The system is not, however, strictly successively inclusive. Whereas 88.3 percent of all patent class–area pairs are generated in at least 50 percent of equally sized and bigger areas, only 20.5 percent of pairs are 100 percent strictly hierarchical.
本文借鉴了中心地理论(CPT)的几个经验规律,以加深对美国城市系统中发明分布不均匀的理解,特别是构成国家技术进步的巨大专业化阵列。CPT将城市系统描述为地方的集合,其中的功能随着城市规模的增加而增加。小城市功能少,大城市功能多。如果大城市具有小城市的全部功能和一些附加功能,那么一个长期的等级体系就是先后包容性的。这里调查的功能是2000年至2011年期间分布在美国366个大都市地区的399个专利类别。强有力的证据表明,获得大量奖励的专利类别广泛分布在整个城市体系中。这导致在稳健类别中活跃于产生专利的区域的平均大小明显小于在不寻常类别中产生专利的区域的平均大小。小城市通过在最活跃和最普遍的发明专业中产生专利,与国家的技术进步联系在一起。大城市的发明家更有可能在不寻常的领域进行发明创造。较大的区域明显比较小的区域更加多样化。然而,该系统并不严格地包括先后顺序。尽管88.3%的专利类别-区域对是在至少50%的同等大小和更大的区域中产生的,但只有20.5%的专利类别-区域对是100%严格分级的。
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引用次数: 3
Modeling and Visualizing Regular Human Mobility Patterns with Uncertainty: An Example Using Twitter Data 建模和可视化具有不确定性的常规人类流动模式:使用Twitter数据的示例
Pub Date : 2015-09-23 DOI: 10.1080/00045608.2015.1081120
Qunying Huang, D. Wong
Traditional space–time paths show the spatiotemporal trajectories of individuals in one to several days. Based on data for such short periods, these space–time paths might not be able to show regular activity patterns, which are pertinent to various types of planning and policy analysis. Travel data gathered for longer periods might capture regular activity patterns, but footprints captured by these data also include irregular activities, introducing noises or uncertainty. Our objective is to determine the representative spatiotemporal trajectories of individuals, accounting for stochastic disturbances and spatiotemporal variability, but using activity data with longer duration. Therefore, we explore using Twitter data, which have relatively low and irregular spatial and temporal resolutions. This article introduces a methodology to construct individual representative space–time paths using various aggregation and spatiotemporal clustering techniques. To depict and visualize spatiotemporal trajectories with uncertain information, we propose space–time cones of variable sizes to reflect the spatial precision of the paths and use colors on the cones to represent the confidence level. To illustrate the proposed methodology, we use the geo-tagged tweets for an extended period. Our analysis indicates that the representative space–time path reasonably describes an individual's regular activity patterns. As visual elements, cones and cone colors effectively show the varying geographical precision along the path and changing certainty levels across different path segments, respectively.
传统的时空路径显示个体在一天到几天内的时空轨迹。基于如此短时间的数据,这些时空路径可能无法显示与各种规划和政策分析相关的常规活动模式。长时间收集的旅行数据可能会捕捉到规律的活动模式,但这些数据捕捉到的足迹也包括不规则的活动,引入噪音或不确定性。我们的目标是确定个体的代表性时空轨迹,考虑随机干扰和时空变异性,但使用持续时间较长的活动数据。因此,我们使用Twitter数据进行探索,Twitter数据具有相对较低且不规则的时空分辨率。本文介绍了一种利用各种聚合和时空聚类技术构建个体代表性时空路径的方法。为了描述和可视化具有不确定信息的时空轨迹,我们提出了可变尺寸的时空锥来反映路径的空间精度,并使用锥上的颜色来表示置信水平。为了说明所提出的方法,我们在较长一段时间内使用地理标记的tweet。我们的分析表明,代表性时空路径合理地描述了个体的规律活动模式。作为视觉元素,锥体和锥体颜色分别有效地表现了沿路径的地理精度变化和不同路径段的确定性变化。
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引用次数: 86
Harm J. de Blij, 1935–2014 Harm J.de Blij,1935–2014
Pub Date : 2015-09-18 DOI: 10.1080/00045608.2015.1079989
Peter O. Muller, Alexander B. Murphy
What Carl Sagan did for cosmology, Harm de Blij is doing for geography. See, hear, or read him and you will sign on for a continuing course in a subject that he has brought alive like no one else i...
卡尔·萨根(Carl Sagan)为宇宙学所做的,哈姆·德·布莱吉(Harm de Blij)正在为地理学所做的。看到、听到或读到他的作品,你就会报名参加一门继续课程,这门课程是他让人耳目一新的……
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引用次数: 0
A Multiscalar Analysis of Neighborhood Composition in Los Angeles, 2000–2010: A Location-Based Approach to Segregation and Diversity 2000-2010年洛杉矶社区组成的多标量分析:基于区位的隔离和多样性分析方法
Pub Date : 2015-09-04 DOI: 10.1080/00045608.2015.1072790
W. Clark, Evan Anderson, John Östh, B. Malmberg
There continues to be cross-disciplinary interest in the patterns, extent, and changing contexts of segregation and spatial inequality more generally. The changes are clearly context dependent but at the same time there are broad generalizations that arise from the processes of residential sorting and selection. A major question in U.S. segregation research is how the growth of Asian and Hispanic populations is influencing patterns of segregation and diversity at the neighborhood level. In this article we use a variant of a nearest neighbor approach to map, graph, and evaluate patterns of race and ethnicity at varying scales. We show that using a multiscalar approach to segregation can provide a detailed and more complete picture of segregation. The research confirms work from other studies that segregation is decreasing between some groups and increasing between others, and the patterns, and processes can be described as dynamic diversity. In a series of maps of ethnic clusters and population homogeneity we show how metropolitan areas, represented in this case by Los Angeles, now display patterns of complex living arrangements with multiple groups inhabiting both local neighborhoods and wider community spheres.
在更普遍的隔离和空间不平等的模式、程度和变化背景方面,继续存在跨学科的兴趣。这些变化显然与环境有关,但同时,从住宅分类和选择的过程中产生了广泛的概括。美国种族隔离研究的一个主要问题是亚洲和西班牙裔人口的增长如何影响社区层面的种族隔离模式和多样性。在本文中,我们使用最近邻方法的一种变体来绘制、绘制和评估种族和民族在不同尺度上的模式。我们表明,使用多标量方法来分离可以提供详细和更完整的分离图像。这项研究证实了其他研究的结论,即一些群体之间的隔离正在减少,而另一些群体之间的隔离正在增加,这种模式和过程可以被描述为动态多样性。在一系列种族集群和人口同质性的地图中,我们展示了以洛杉矶为代表的大都市地区,如何呈现出复杂的生活安排模式,多个群体居住在当地社区和更广泛的社区领域。
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引用次数: 106
期刊
Annals of the Association of American Geographers. Association of American Geographers
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