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#35875 Perioperative fluid fasting in elective upper limb surgery in a tretiary orthopaedic hospital #35875三级骨科医院择期上肢手术围手术期禁食
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.433
Rhys Williams, Mruthunjaya Hulgur

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page) Application for ESRA Abstract Prizes: I don’t wish to apply for the ESRA Prizes

Background and Aims

Fasting guidelines have been established to reduce the risk of a pulmonary aspiration event in patients undergoing anaesthesia. Excessive fasting can contribute to anxiety, nausea, dehydration and physiological derangement. In practice, patients are likely to be fasted for longer than the conventional times. The aim of our project was to identify the average length of fluid fast in our elective patients.

Methods

This was a retrospective case-note review of 50 patients undergoing elective upper limb surgery in our tertiary orthopaedic institution. Their reported fasting times for solids and liquids were recorded. Their sent for operation times were interrogated from Operating Room Management Information System (ORMIS) computer system. This information was subsequently compiled into a datasheet.

Results

The average fasting time for solids was 14h 30mins. The average conventional fluid fasting time was 3h 29 mins. When this adjusted to a sent for operating time, the average time was 6 h 11min (range 0min to 18h 10 min). 16% of patients included in the study were fluid fasted for greater than 12 hours.

Conclusions

Our study revealed excessive fasting times in the majority of our patients. Evidently a two-hour fluid fasting target becomes a longer fast in the real world. We have adapted out current fasting guidelines to align with progressive institutions which use a sip-till-send approach to allow 170ml of water each hour until sent for operating (Checketts 2023). We will re-audit these times after implementation of the guideline.
请确认已申请或授予伦理委员会批准:不相关(见本页底部信息)ESRA申请摘要奖励:我不希望申请ESRA奖励背景和目的已经建立了禁食指南,以降低接受麻醉的患者肺部误吸事件的风险。过度禁食会导致焦虑、恶心、脱水和生理紊乱。实际上,患者的禁食时间可能比传统时间更长。我们项目的目的是确定我们的择期患者液体禁食的平均长度。方法回顾性分析我院三级骨科收治的50例选择性上肢手术患者。他们报告的固体和液体禁食时间被记录下来。通过手术室管理信息系统(ORMIS)计算机系统查询患者的手术时间。这些资料随后被汇编成一份数据表。结果固体禁食时间平均为14h 30min。常规液体禁食时间平均为3h 29 min。当此调整为发送操作时间时,平均时间为6小时11分钟(范围为0分钟至18小时10分钟)。研究中16%的患者液体禁食超过12小时。结论:我们的研究显示大多数患者空腹时间过长。显然,两个小时的液体禁食目标在现实世界中变得更长了。我们已经调整了目前的禁食指南,以与先进的机构保持一致,这些机构使用小口-直到送出的方法,每小时允许170毫升的水,直到送出操作(Checketts 2023)。我们将在指南实施后重新审核这些时间。
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引用次数: 0
#35801 Fungal osteomyelitis of TMJ and skull base caused by chronic otitis media #35801慢性中耳炎引起的TMJ和颅底真菌骨髓炎
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.391
Bok Eum Kim

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page)

Background and Aims

Chronic otitis media (COM) is an inflammatory disease of the middle ear. The symptoms of COM are ear pain, intracranial complication. Skull base osteomyelitis (SBO) may occur by transmission of infection based on COM. In this paper, we present a patient with untreated COM who was diagnosed with SBO.

Methods

A-67-year-old man visited our clinic with left TMJ pain. He had taken NSAIDs, and his symptoms had been relieved but not disappeared. CT showed no abnormal finding. But he showed familiar pain in the left TMJ. He was diagnosed with left TMJ arthralgia. After medication, the pain in the left TMJ was disappeared. 6 months later, he re-visited clinic and presented with pricking pain in the same area. CT revealed erosive change in left TMJ. He was diagnosed with left TMJ osteoarthritis and prescribed medicines including amoxicillin, ketorolac. However, his severe pain had been persisted.

Results

CRP is 49.1. A MRI showed heterogeneous enhancement in the left condyle. He was referred to ENT and left mastoidectomy was performed. When the microbial cultures of resected specimens were performed, candida was found, which led to the final diagnosis of SBO.

Conclusions

In case of atypical pain on TMJ, it is necessary to take a careful history taking. Untreated COM can spread, leading to SBO. Untreated SBO can lead to death. If COM patient has a history of systemic diseases, fungal osteomyelitis may develop up to the skull base, leading to bony change. It is important to diagnose by using CT/MRI.
背景和目的慢性中耳炎(Chronic otitis media, COM)是一种中耳炎症性疾病。COM的症状为耳痛、颅内并发症。颅底骨髓炎(SBO)可能是基于COM的感染传播而发生的。在本文中,我们报告了一位未经治疗的COM患者被诊断为SBO。方法a -67岁男性以左侧颞下颌关节疼痛就诊。他服用了非甾体抗炎药,他的症状有所缓解,但没有消失。CT未见异常。但他的左颞下颌关节有常见的疼痛。他被诊断为左颞下颌关节痛。用药后,左侧颞下颌关节疼痛消失。6个月后再次就诊,同一部位出现刺痛感。CT显示左侧TMJ糜烂改变。他被诊断为左颞下颌关节骨关节炎,并开了阿莫西林、酮酸等药物。然而,他的剧痛一直持续着。结果CRP为49.1。MRI显示左髁不均匀强化。他被转介到耳鼻喉科,并进行了左侧乳突切除术。当切除标本进行微生物培养时,发现念珠菌,最终诊断为SBO。结论对不典型颞下颌关节疼痛的患者,应进行详细的病史记录。未经治疗的COM会扩散,导致SBO。未经治疗的SBO会导致死亡。如果COM患者有全身性疾病史,真菌骨髓炎可能发展到颅底,导致骨改变。CT/MRI诊断非常重要。
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引用次数: 0
#35918 A randomized control trial to evaluate the effects of Ketofol versus propofol on cerebral oxygenation in patients undergoing Trans-sphenoidal pituitary surgery under total intravenous anesthesia #35918一项随机对照试验,评估酮酚与异丙酚对全静脉麻醉下经蝶窦垂体手术患者脑氧合的影响
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.436
Arvind Chaturvedi

Please confirm that an ethics committee approval has been applied for or granted: Yes: I’m uploading the Ethics Committee Approval as a PDF file with this abstract submission Application for ESRA Abstract Prizes: I don’t wish to apply for the ESRA Prizes

Background and Aims

Propofol causes hypotension and respiratory depression while Ketamine preserves airway reflexes and respiration, prevents hypotension. Ketofol (combination of Propofol and Ketamine) has shown to have cumulative effects on analgesia, and hypnosis,requiring lower dose of drug and less adverse effects ,maintains hemodynamics. Effect of various intravenous anaesthetic agents on cerebral oxygenation has not been evaluated. We compared the effects of Ketofol&Propofol on cerebral oxygenation in patients undergoing pituitary surgery.

Methods

Study ,conducted on 50 patients,undergoing pituitary surgery.Patients divided into Ketofol&Propofol groups,25 patients each. Intra-operative cerebral oxygenation (rSO2), hemodynamic parameters ,SpO2, Total analgesic,time to emergence and time to first post-operative analgesia ,recorded.

Results

In both groups, baseline values of rSO2 were within normal limits. rSO2 values were significantly higher in Ketofol-group than Propofol-group all- time, on both sides. rSO2 during surgery were higher in Ketofol-group and lower in Propofol-group on both sides . rSO2 values at specific stages of surgery/anaesthesia were higher than baseline in Ketofol-group and lower in Propofol-group on both side, .Intraoperative hemodynamic parameters was similar in the two groups, but significant increase in HR and MAP in Propofol group was observed during various stimuli (anaesthesia/surgical) compared to Ketofol. Episodes of hypotension were significantly higher in Propofol compared to Ketofol group Intraoperative requirement of opioid , propofol was significantly reduced in Ketofol-group .Time to first analgesic was longer in Ketofol than Propofol-group, emergence from anaesthesia was significantly longer in Propofol group.

Conclusions

In patients with pituitary surgery, Ketofol provides better cerebral oxygenation, hemodynamic stability , rapid emergence , prolong analgesia, compared to Propofol.

Attachment

Sudeshna , ethics.pdf
请确认伦理委员会的批准已经申请或授予:是的:我正在将伦理委员会的批准以PDF文件的形式上传,并随摘要提交ESRA申请摘要奖项:我不希望申请ESRA奖项背景和目的异丙酚导致低血压和呼吸抑制,而氯胺酮保持气道反射和呼吸,防止低血压。酮酚(异丙酚和氯胺酮的混合物)已显示出对镇痛的累积效应,而催眠所需的药物剂量较低,不良反应较少,可维持血液动力学。各种静脉麻醉药对脑氧合的影响尚未得到评价。我们比较了酮叶酸和异丙酚对垂体手术患者脑氧合的影响。方法对50例垂体手术患者进行研究。患者分为酮叶酸组和异丙酚组,每组25例。记录术中脑氧合(rSO2)、血流动力学参数、SpO2、总镇痛药、出现时间及术后首次镇痛时间。结果两组rSO2基线值均在正常范围内。无论何时,酮福尔组的rSO2值均显著高于异丙酚组。术中双侧rSO2水平,酮酚组较高,异丙酚组较低。在手术/麻醉的特定阶段,双侧rSO2值酮福组高于基线,异丙酚组低于基线,两组术中血流动力学参数相似,但在各种刺激(麻醉/手术)下,异丙酚组的HR和MAP明显高于酮福。术中对阿片类药物的需要量、丙泊酚用量均明显降低,首次镇痛时间较丙泊酚组延长,麻醉恢复时间明显延长。结论与异丙酚相比,酮酚在垂体手术患者中提供更好的脑氧合,血流动力学稳定,快速苏醒,延长镇痛时间。附件Sudeshna,伦理学。pdf
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引用次数: 0
#35931 Regional anaesthesia for intubation and maintenance in myasthenia gravis patient with bilateral renal calculi 区域麻醉在重症肌无力合并双侧肾结石患者插管和维持中的应用
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.406
Prashanth Prabhu, Suvina N, Sitara AY, Hemashree G, Poornashree G

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page) Application for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)

Background and Aims

30year old male patient weighing 40kg with a known case of myasthenia gravis was posted for right percutaneous nephrolithotomy and left open urethrolithotomy. Patient had a muscle power of 3/5, hence we wanted to avoid skeletal muscle relaxant to the patient.

Methods

Patient was shifted to operation room, monitors connected, IV cannula established. Anterior neck area was disinfected with surgical spirit. – Bilateral superior Laryngeal nerve block given using 2ml of 2%lignocaine + 2ml of 0.5%bupivacaine. – Translaryngeal block given using 1ml of 2%lignocaine + 1ml of 0.5%bupivacaine. – 2 sprays of 10%lignocaine spray was administered in the posterior pharyngeal area. Later epidural was established at L1-L2. After test dose, epidural was activated with 10ml of 0.5% bupivacaine. BIS monitor was connected. Inj. Dexmedetomidine was administered 40mcg IV over 10 minutes. The patient was preoxygenated for 3 minutes and later Induced with Inj. Propofol 80mg IV. Once BIS was <60, patient was intubated using 7.0 cuffed endotracheal tube and fixed at 21cm. The endotracheal tube cuff was inflated with 5ml of 1%lignocaine to prevent intubation related complications during extubation process.

Results

If BIS>80, Inj. Propofol 20mg IV bolus was given. BIS was maintained around 60 intraoperatively. Patient was maintained intraoperatively by O2: Air = 0.5l:2l. Inj.Propofol at 160 to 320mg/hr, Inj. Dexmedetomidine at 10 to 20mcg/hr and epidural infusion was maintained with 4 to 6ml of 0.25%bupivacaine. Post-Operative patient was extubated the next day in ICU.

Conclusions

Airway block helped in successful management of myasthenia gravis patient without skeletal muscle relaxant for successful surgery.
摘要奖项:本人以麻醉师身份申请(年龄在35岁以下)背景与目的30岁男性,体重40kg,已知重症肌弱,拟行右侧经皮肾镜取石术和左侧开放输尿管取石术。患者的肌力为3/5,因此我们希望避免给患者使用骨骼肌松弛剂。方法将患者移入手术室,连接监护仪,建立静脉插管。颈前区用手术液消毒。-双侧喉上神经阻滞给予2ml 2%利多卡因+ 2ml 0.5%布比卡因。经喉阻滞使用1ml 2%利多卡因+ 1ml 0.5%布比卡因。-在咽后区使用10%利多卡因喷雾剂2剂。后来硬膜外在L1-L2建立。试验给药后,用10ml 0.5%布比卡因激活硬膜外。已连接BIS监视器。Inj。右美托咪定静脉注射40mcg,持续10分钟。患者预充氧3分钟后注射诱导。异丙酚80mg IV。待BIS = 60时,采用7.0折口气管插管,固定于21cm处。在拔管过程中,气管插管袖口充气5ml 1%利多卡因,以防止插管相关并发症。结果BIS>80;给予异丙酚20mg静脉丸。术中BIS维持在60左右。术中维持O2: Air = 0.5l:2l。Inj。异丙酚160 - 320毫克/小时,注射。右美托咪定剂量为10 ~ 20mcg/hr,硬膜外输注0.25%布比卡因4 ~ 6ml。术后患者于次日在ICU拔管。结论气道阻滞有助于无骨骼肌松弛剂的重症肌无力患者手术成功。
{"title":"#35931 Regional anaesthesia for intubation and maintenance in myasthenia gravis patient with bilateral renal calculi","authors":"Prashanth Prabhu, Suvina N, Sitara AY, Hemashree G, Poornashree G","doi":"10.1136/rapm-2023-esra.406","DOIUrl":"https://doi.org/10.1136/rapm-2023-esra.406","url":null,"abstract":"<h3></h3> <b>Please confirm that an ethics committee approval has been applied for or granted:</b> Not relevant (see information at the bottom of this page) <b>Application for ESRA Abstract Prizes:</b> I apply as an Anesthesiologist (Aged 35 years old or less) <h3>Background and Aims</h3> 30year old male patient weighing 40kg with a known case of myasthenia gravis was posted for right percutaneous nephrolithotomy and left open urethrolithotomy. Patient had a muscle power of 3/5, hence we wanted to avoid skeletal muscle relaxant to the patient. <h3>Methods</h3> Patient was shifted to operation room, monitors connected, IV cannula established. Anterior neck area was disinfected with surgical spirit. – Bilateral superior Laryngeal nerve block given using 2ml of 2%lignocaine + 2ml of 0.5%bupivacaine. – Translaryngeal block given using 1ml of 2%lignocaine + 1ml of 0.5%bupivacaine. – 2 sprays of 10%lignocaine spray was administered in the posterior pharyngeal area. Later epidural was established at L1-L2. After test dose, epidural was activated with 10ml of 0.5% bupivacaine. BIS monitor was connected. Inj. Dexmedetomidine was administered 40mcg IV over 10 minutes. The patient was preoxygenated for 3 minutes and later Induced with Inj. Propofol 80mg IV. Once BIS was <60, patient was intubated using 7.0 cuffed endotracheal tube and fixed at 21cm. The endotracheal tube cuff was inflated with 5ml of 1%lignocaine to prevent intubation related complications during extubation process. <h3>Results</h3> If BIS>80, Inj. Propofol 20mg IV bolus was given. BIS was maintained around 60 intraoperatively. Patient was maintained intraoperatively by O2: Air = 0.5l:2l. Inj.Propofol at 160 to 320mg/hr, Inj. Dexmedetomidine at 10 to 20mcg/hr and epidural infusion was maintained with 4 to 6ml of 0.25%bupivacaine. Post-Operative patient was extubated the next day in ICU. <h3>Conclusions</h3> Airway block helped in successful management of myasthenia gravis patient without skeletal muscle relaxant for successful surgery.","PeriodicalId":80519,"journal":{"name":"Archaeologia aeliana, or, Miscellaneous tracts relating to antiquity","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135685778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
#36044 Perioperative hypersensitivity reaction after an ophtalmologic block: case report #36044眼科阻滞后围手术期超敏反应一例报告
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.400
Anderson Gonçalves, Paulo Sérgio M M Serzedo, Flávio Coelho Barroso

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page)

Background and Aims

Perioperative hypersensitivity reactions (PHR) are of great concern to anesthesiologists daily. During a procedure, several agents are administered sequentially in any anesthesia, which can trigger allergic reactions of lesser or greater severity. Otherwise, anaphylaxis is a severe, life-threatening, systemic allergic reaction that occurs rapidly after exposure to a sensitizing agent.

Results

Case report: 56 years-old female, ASA P1, without any known allergies, was admitted to right eye trabeculectomy. Sedation was performed with midazolam and fentanyl to perform the peribulbar block of the eye under adequate asepsis, with injection of 5 ml of 1% ropivacaine and 300 UI of hyaluronidase, with Nicoll Scale, equal to 8, four-quadrant akinesia. After 3 hours, the patient presented slight edema in periorbital tissue, with spontaneous regression of the condition. After 5 days, the patient returned to the clinic to perform the same surgery the eye due procedure failure. After a few minutes from the blockade, the patient presented an important periorbital cold edema, associated with nauseas and urticaria, and the diagnostic hypothesis of PHR class II of Ring & Messmer Scale was suggested. The treatment was immediately performed with aliquots of 20mcg of adrenaline, 250 mg of hydrocortisone and clinical support, that led to regression of the symptoms.

Conclusions

Discussion

Recently, a new consensus was released about the nomenclature of perioperative hypersensitivity, since some terms are not used anymore. Besides that, the variability of symptoms challenges the anesthesiologist in care of the patient, that can be able to diagnose and treat any suspected perioperative allergic reactions.
背景和目的围手术期超敏反应(PHR)是麻醉医师每天非常关注的问题。在手术过程中,在任何麻醉中顺序使用几种药物,这可能引发或轻或重的过敏反应。否则,过敏反应是一种严重的、危及生命的全身性过敏反应,在接触致敏剂后迅速发生。结果病例报告:56岁女性,ASA P1,无任何已知过敏,接受右眼小梁切除术。给予咪达唑仑和芬太尼镇静,在充分无菌条件下对眼球进行球周阻滞,注射1%罗哌卡因5 ml,透明质酸酶300 UI,尼科尔评分,等于8分,四象限肌动障碍。3小时后,患者眼眶周围组织出现轻度水肿,病情自行消退。5天后,由于手术失败,患者返回诊所进行相同的手术。阻断几分钟后,患者出现重要的眶周冷水肿,伴有恶心和荨麻疹,诊断假设为Ring &提出了梅斯默量表。立即给予肾上腺素20微克、氢化可的松250毫克等量治疗和临床支持,导致症状消退。关于围手术期超敏反应的命名近来有了新的共识,因为一些术语已不再使用。除此之外,症状的可变性对麻醉医生在护理患者时提出了挑战,他们可以诊断和治疗任何可疑的围手术期过敏反应。
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引用次数: 0
#36390 A case of Anti Synthetase Syndrome with Interstial lung disease for laparoscopic surgery #36390腹腔镜手术抗合成酶综合征合并间质性肺病1例
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.397
Zanariah Yahaya

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page) Application for ESRA Abstract Prizes: I don’t wish to apply for the ESRA Prizes

Background and Aims

Anti-synthetase syndrome (ASS ) is a rare chronic autoimmune disorder of unknown cause. The hallmark of ASS is the presence of serum autoantibodies directed against amino act-tRNA synthetase. ASS is 2-3 times more common in women than in men. The morbidity and mortality of ASS are usually linked to pulmonary findings .

Methods

48 years old lady who was diagnosed having Anti -Synthetase syndrome in 2020. She has interstitial lung disease with pulmonary function test of FeV1 1.4 (61%) FVC 1.65 (61%) and DLLO 40% .She was scheduled for total laparoscopic hysterectomy and salphingoophrectomy . She was assessed by respiratory unit pre operative where surgical risk was moderate , aim for early mobilisation and suggested for spinal anaesthesia if possible . Rheumatologist was also consulted preoperatively .The surgery was conducted under general anaesthesia with IPPV and securing the airway , neuromuscular blockade monitoring and surgeon was told to be careful with the intraabdominal pressure . The surgery went well she was extubated with sugamadex .

Conclusions

ASS is a rare idiopathic inflammatory multi system disorder which can lead to serious postoperative complications secondary to muscle weakness and respiratory complications. As laparoscopic surgery requires inflation of gas to intra abdominal cavity and head down position during the surgery , regional anaesthesia would be a challenge for this patient . A multidisciplinary teams including respiratory unit , rheumatology , physiotherapist and anaesthesiology is essential in the care of a patient with ASS.

Attachment

Esra Abstract.pdf
申请ESRA摘要奖项:我不希望申请ESRA奖项背景和目的抗合成酶综合征(ASS)是一种罕见的慢性自身免疫性疾病,原因不明。ASS的标志是血清中存在针对氨基- trna合成酶的自身抗体。ASS在女性中的发病率是男性的2-3倍。ASS的发病率和死亡率通常与肺部表现有关。方法2020年确诊为抗合成酶综合征的48岁女性。她患有间质性肺疾病,肺功能检查FeV1 1.4 (61%) FVC 1.65 (61%) dlo 40%,计划行腹腔镜全子宫切除术和脑脊膜切除术。术前由呼吸科评估,手术风险中等,目标是早期活动,并建议在可能的情况下进行脊髓麻醉。术前还咨询了风湿病学家。手术是在全麻下进行的,有IPPV和固定气道,神经肌肉阻滞监测,外科医生被告知要小心腹内压。手术进行得很顺利,她拔管时用了糖糖。结论ASS是一种罕见的特发性炎性多系统疾病,可导致严重的术后并发症,继发于肌肉无力和呼吸系统并发症。由于腹腔镜手术需要向腹腔内充气,手术过程中需要头部朝下,因此局部麻醉对该患者来说是一个挑战。包括呼吸科、风湿病科、物理治疗师和麻醉科在内的多学科团队在ASS患者的护理中至关重要
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引用次数: 0
#35209 Incidence of nosocomial infections in icu of a tertiary care hospital and antibiogram #35209三级护理医院icu的医院感染发生率和抗生素谱
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.437
Sami Ur Rehman

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page)

Background and Aims

Antimicrobial resistance (AMR) has become a global issue. Not only decreasing the treatment options but serious threat to low-income countries associated with both misuse and overuse of antibiotics. This study has determined the antibiogram profile of patients admitted in SURGICAL icu (SICU) at Doctors Hospital and Medical Centre, Lahore.

Methods

This study was retrospective cross-sectional in nature.Total 502 patients were admitted in ICU during our study period.Blood, tracheal and urine culture reports of 364 patients were recorded for the purpose of study.All cultures were processed in accordance with standard microbiological protocols defined by CLSI. CLED used for urine cultures, while Mac-Conkey, Choclate and Blood Agar were being used for tracheal and sputum cultures. Blood cultures were processed on BACT/ALERT automated blood culture system.Statistical analysis were performed using the SPSS 64-bit version.

Results

Among 364 patients analyzed in the study, the cultures obtained from different sites were Blood (54%), Urine (33%) and tracheal (13%). Among blood cultures, no organism was isolated.Among tracheal cultures, most common organisms isolated were Klebsiella (5), followed by Acinetobacter (4) and Pseudomonas (3).Among urine cultures, most common organism isolated was E. coli (4), then Klebsiella (3) and Pseudomonas (2).Vancomycin and Linezolid showed zero percent resistance to Staphylococcus sp. Collistin showed zero percent resistance for Acinetobacter and Klebsiella. Moxifloxacin was resistant for E. coli.

Conclusions

The gram-negative bacteria were the major cause of infection in the ICU. Gram negative organisms(88.46%) were detected more than gram positive organisms(11.53%). We need to prescribe broad-spectrum antibiotics more wisely to reduce pressure on sensitive strains.

Attachment

antibiogram dhmc.docx
请确认是否已申请或批准伦理委员会的批准:不相关(见本页底部的信息)背景和目的抗菌素耐药性(AMR)已成为一个全球性问题。不仅减少了治疗选择,而且与抗生素的滥用和过度使用有关,对低收入国家构成严重威胁。本研究确定了拉合尔医生医院和医疗中心外科icu (SICU)住院患者的抗生素谱。方法本研究为回顾性横断面研究。在我们的研究期间,共有502例患者入住ICU。记录364例患者的血液、气管和尿液培养报告。所有培养物均按照CLSI定义的标准微生物学方案进行处理。cle用于尿液培养,而Mac-Conkey, chocolate和Blood Agar用于气管和痰培养。血培养在BACT/ALERT自动血培养系统上进行。采用SPSS 64位版进行统计分析。结果本组364例患者中,不同部位培养物分别为血液(54%)、尿液(33%)和气管(13%)。在血液培养中,没有分离出任何有机体。在气管培养中,最常见的细菌是克雷伯菌(5),其次是不动杆菌(4)和假单胞菌(3)。在尿液培养中,最常见的细菌是大肠杆菌(4),其次是克雷伯菌(3)和假单胞菌(2)。万古霉素和利奈唑胺对葡萄球菌的耐药性为0%,粘菌素对不动杆菌和克雷伯菌的耐药性为0%。莫西沙星对大肠杆菌耐药。结论革兰氏阴性菌是ICU感染的主要原因。革兰氏阴性菌(88.46%)多于革兰氏阳性菌(11.53%)。我们需要更明智地开出广谱抗生素,以减轻对敏感菌株的压力。附件抗生素图dhmc.docx
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引用次数: 0
#36517 Perioperative management of antithrombotic therapy in hip fracture surgery #36517髋部骨折围手术期抗栓治疗的管理
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.420
Amparo Izquierdo Aicart, Maria Sempere, Alba Montoya, Rafael Badenes

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page) Application for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)

Background and Aims

Hip fracture surgery has a huge prevalence and morbimortality. One of the main reasons of delaying surgery is the use of anticoagulants/antiplatelet therapies, being these patients old and with comorbidities. Risks of delay surgery are higher than surgical bleeding or vertebral canal haematoma; so promp surgery in first 48 hours should be facilitated.

Methods

In this review we search the main guidelines about perioperative management of antithrombotic drugs and locorregional guidelines; focusing in hip fracture surgery and also its management when neuroaxial anesthesia is performed.

Results

-With antiplatelet drugs therapy surgery should not be delay. In case of PY12 inhibitors neuraxial anesthesia is not recommended. -With vitamin K antagonists therapy, reversal with vitamin K/prothrombin complex concentrate (PCC) should be done for ensure INR <1,8. Neuraxial anesthesia can be performed when INR <1,5. -With new oral anticoagulants (NOAC) interruption intervals of 1-2 half-life is recommended (12-24 hours without impaired kidney function). Neuraxial anesthesia is not recommended in early surgery without a specific coagulation test. If there is a risk performing general anesthesia we should consider use of reversal agents or specific tests.

Conclusions

Early hip fracture surgery is safe in patients taking anticoagulant/antiplatelet drugs. Special attention should we pay in perioperative timing when neuraxial anesthesia is performed.
请确认已申请或授予伦理委员会批准:不相关(见本页底部信息)ESRA申请摘要奖项:我以麻醉师身份申请(年龄在35岁以下)背景和目的髋部骨折手术具有巨大的患病率和死亡率。延迟手术的主要原因之一是使用抗凝血剂/抗血小板治疗,因为这些患者年龄大且有合并症。延迟手术的风险高于手术出血或椎管血肿;因此,应在头48小时内进行及时手术。方法检索抗栓药物围手术期管理的主要指南和地方指南;重点介绍髋部骨折手术及其在神经轴向麻醉下的处理。结果-配合抗血小板药物治疗手术不应延误。在PY12抑制剂的情况下,不建议使用轴向麻醉。-使用维生素K拮抗剂治疗时,应使用维生素K/凝血酶原复合物浓缩物(PCC)进行逆转,以确保INR <1,8。当INR <1,5时可进行轴向麻醉。-使用新的口服抗凝剂(NOAC)时,建议中断时间间隔为1-2个半衰期(12-24小时不损害肾功能)。如果没有特定的凝血试验,不建议在早期手术中使用轴向麻醉。如果有进行全身麻醉的风险,我们应该考虑使用逆转剂或特定的测试。结论早期髋部骨折患者服用抗凝/抗血小板药物是安全的。神经轴麻醉的围术期时机应特别注意。
{"title":"#36517 Perioperative management of antithrombotic therapy in hip fracture surgery","authors":"Amparo Izquierdo Aicart, Maria Sempere, Alba Montoya, Rafael Badenes","doi":"10.1136/rapm-2023-esra.420","DOIUrl":"https://doi.org/10.1136/rapm-2023-esra.420","url":null,"abstract":"<h3></h3> <b>Please confirm that an ethics committee approval has been applied for or granted:</b> Not relevant (see information at the bottom of this page) <b>Application for ESRA Abstract Prizes:</b> I apply as an Anesthesiologist (Aged 35 years old or less) <h3>Background and Aims</h3> Hip fracture surgery has a huge prevalence and morbimortality. One of the main reasons of delaying surgery is the use of anticoagulants/antiplatelet therapies, being these patients old and with comorbidities. Risks of delay surgery are higher than surgical bleeding or vertebral canal haematoma; so promp surgery in first 48 hours should be facilitated. <h3>Methods</h3> In this review we search the main guidelines about perioperative management of antithrombotic drugs and locorregional guidelines; focusing in hip fracture surgery and also its management when neuroaxial anesthesia is performed. <h3>Results</h3> -With antiplatelet drugs therapy surgery should not be delay. In case of PY12 inhibitors neuraxial anesthesia is not recommended. -With vitamin K antagonists therapy, reversal with vitamin K/prothrombin complex concentrate (PCC) should be done for ensure INR <1,8. Neuraxial anesthesia can be performed when INR <1,5. -With new oral anticoagulants (NOAC) interruption intervals of 1-2 half-life is recommended (12-24 hours without impaired kidney function). Neuraxial anesthesia is not recommended in early surgery without a specific coagulation test. If there is a risk performing general anesthesia we should consider use of reversal agents or specific tests. <h3>Conclusions</h3> Early hip fracture surgery is safe in patients taking anticoagulant/antiplatelet drugs. Special attention should we pay in perioperative timing when neuraxial anesthesia is performed.","PeriodicalId":80519,"journal":{"name":"Archaeologia aeliana, or, Miscellaneous tracts relating to antiquity","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135686160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
#36494 Ultrasound-guided serratus posterior superior block in a case of multitrauma: first catheter application in the novel block 超声引导下后上锯肌阻滞1例:导管在新型阻滞中的首次应用
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.427
Serkan Tulgar, Dilan Akyurt, Caner Genc

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page) Application for ESRA Abstract Prizes: I apply as an Anesthesiologist (Aged 35 years old or less)

Background and Aims

Ultrasound-guided Serratus posterior superior intercostal plane (SPSIP) block is a newly defined interfascial plane block and targets the shoulder and hemithorax. Ultrasound-guided Serratsu posterior superior plane (SPSIP) block is a newly defined interfascial plane block and targets the shoulder and hemithorax. Extensive spread was reported from C7 to T7 in the cadaveric study, and from C3 to T10 in clinical applications [1]. Herein, we report our SPSIP block and first catheterization in a critical patient.

Methods

A 48-year-old male patient presented with a fall, resulting in fractures of the left scapula, radius, pelvis, and acetabulum, along with multiple rib fractures and a pneumothorax.He had severe pain due to scapula and rib fractures, thoracic tube, and began to desaturate (88-90%) because he had difficulty in breathing deeply and atelectasis was developing.

Results

Despite routine analgesia, the patient started to deteriorate and left SPSIP block was applied with 40 mL of local anesthetic. Despite routine analgesia, the patient started to deteriorate and left SPSIP block was applied with 40 mL of local anesthetic. When asked about the patient‘s pain originating from the shoulder and thorax, he reported that his NRS decreased from 9 to 2. The next day, a catheter was inserted in the same plane. 20 ml of contrast was administered, allowing determination of the contrast spread from T1 to T4, reaching up to the anterior axillary line (figure 1).

Conclusions

Ultrasound-guided SPSIP block can effectively alleviate pain in the shoulder and hemithorax and may be beneficial in patients with scapula and rib fractures.
摘要奖项:本人以麻醉师身份申请(年龄在35岁以下)背景与目的超声引导下锯肌后上肋间平面(SPSIP)阻滞是一种新定义的筋膜间平面阻滞,针对肩部和半胸。超声引导Serratsu后上平面阻滞(SPSIP)是一种新定义的筋膜间平面阻滞,主要作用于肩部和半胸。尸体研究报道从C7到T7的广泛传播,临床应用报道从C3到T10的广泛传播[1]。在此,我们报告了一例危重患者的SPSIP阻滞和首次置管。方法一名48岁男性患者因跌倒导致左肩胛骨、桡骨、骨盆和髋臼骨折,并伴有多处肋骨骨折和气胸。由于肩胛骨和肋骨骨折,他有严重的疼痛,胸管,并开始去饱和(88-90%),因为他呼吸困难和肺不张发展。结果在常规镇痛的情况下,患者病情开始恶化,左SPSIP阻滞应用局麻40ml。尽管常规镇痛,患者开始恶化,左SPSIP阻滞应用40ml局麻。当被问及患者源自肩部和胸部的疼痛时,他报告说他的NRS从9下降到2。第二天,在同一平面插入导管。给药20ml造影剂,测定造影剂从T1到T4的扩散,达到腋前线(图1)。结论超声引导下SPSIP阻滞可有效缓解肩部和半胸疼痛,对肩胛骨和肋骨骨折患者可能有益。
{"title":"#36494 Ultrasound-guided serratus posterior superior block in a case of multitrauma: first catheter application in the novel block","authors":"Serkan Tulgar, Dilan Akyurt, Caner Genc","doi":"10.1136/rapm-2023-esra.427","DOIUrl":"https://doi.org/10.1136/rapm-2023-esra.427","url":null,"abstract":"<h3></h3> <b>Please confirm that an ethics committee approval has been applied for or granted:</b> Not relevant (see information at the bottom of this page) <b>Application for ESRA Abstract Prizes:</b> I apply as an Anesthesiologist (Aged 35 years old or less) <h3>Background and Aims</h3> Ultrasound-guided Serratus posterior superior intercostal plane (SPSIP) block is a newly defined interfascial plane block and targets the shoulder and hemithorax. Ultrasound-guided Serratsu posterior superior plane (SPSIP) block is a newly defined interfascial plane block and targets the shoulder and hemithorax. Extensive spread was reported from C7 to T7 in the cadaveric study, and from C3 to T10 in clinical applications [1]. Herein, we report our SPSIP block and first catheterization in a critical patient. <h3>Methods</h3> A 48-year-old male patient presented with a fall, resulting in fractures of the left scapula, radius, pelvis, and acetabulum, along with multiple rib fractures and a pneumothorax.He had severe pain due to scapula and rib fractures, thoracic tube, and began to desaturate (88-90%) because he had difficulty in breathing deeply and atelectasis was developing. <h3>Results</h3> Despite routine analgesia, the patient started to deteriorate and left SPSIP block was applied with 40 mL of local anesthetic. Despite routine analgesia, the patient started to deteriorate and left SPSIP block was applied with 40 mL of local anesthetic. When asked about the patient‘s pain originating from the shoulder and thorax, he reported that his NRS decreased from 9 to 2. The next day, a catheter was inserted in the same plane. 20 ml of contrast was administered, allowing determination of the contrast spread from T1 to T4, reaching up to the anterior axillary line (figure 1). <h3>Conclusions</h3> Ultrasound-guided SPSIP block can effectively alleviate pain in the shoulder and hemithorax and may be beneficial in patients with scapula and rib fractures.","PeriodicalId":80519,"journal":{"name":"Archaeologia aeliana, or, Miscellaneous tracts relating to antiquity","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135686237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
#34837 Decision-making framework to undertake regional anaethesia in patients with poor comorbidities and diminished mental capacity #34837对不良合并症和智力下降的患者进行局部麻醉的决策框架
Pub Date : 2023-09-01 DOI: 10.1136/rapm-2023-esra.402
Tong-Khee Tan

Please confirm that an ethics committee approval has been applied for or granted: Not relevant (see information at the bottom of this page) Application for ESRA Abstract Prizes: I don’t wish to apply for the ESRA Prizes

Background and Aims

Informed consent forms the cornerstone of regional anaesthesia. In patients lacking mental capacity, risks of a performing a particular regional technique/alternatives would not be able to be conveyed. The decision to use regional techniques may make anaesthetists uncomfortable especially if the incompetent patient has no family members/legal representatives. This poster suggests using Jonsens’s 4box approach(1) to aid anaesthetists’decision-making/justification when using regional techniques in sub-optimal patients.

Methods

85 year old severely demented Mr.X, bedbound, was from state-run nursing home for destitutes. He was admitted with wet gangrene of right forefoot,in severe distress. He developed a sepsis-related myocardial infarction needing dual anti-platelets(clopidogrel,aspirin). A debridement/toes amputation was planned,under popliteal/saphenous nerve block,despite his coagulopathic state.

Results

Box1:Medical indications. To remove source of sepsis and pain relief, without general anaesthetic risks. Box2:Patient preference. Would he want surgery under regional block when coagulopathic, with complications such as haematoma/nerve injury? Lacking capacity and needing urgent procedure, the anaesthetist made decisions based on best interest/neccesity. Box3:Quality of life. His premorbid state was miserable but his current state worse as he was in pain and septic. Box4:Contextual features. There was no dignity having a smelly/painful septic gangrenous foot. Regional technique was safer than general anaesthetic in view of his recent infarction. Not without risks, the peripheral nature of the block and using ultrasound guidance made it safer.

Conclusions

The four box approach was used to guide decision to perform a nerve block in a coagulopathic patient, who was unable to discuss risks and alternatives. The over-riding consideration acutely was his dignity, comfort.

Attachment

AbstractJonsen AR.docx
请确认已申请或授予伦理委员会批准:不相关(见本页底部信息)ESRA摘要奖申请:我不希望申请ESRA奖背景和目的知情同意书是区域麻醉的基石。在缺乏精神能力的患者中,执行特定区域技术/替代方案的风险将无法传达。使用局部麻醉的决定可能会让麻醉师感到不舒服,尤其是当不称职的病人没有家庭成员/法律代表时。这张海报建议使用Jonsens的4box方法(1)来帮助麻醉师在对非最佳患者使用局部技术时做出决策/证明。方法85岁重度痴呆患者x先生,卧床不起,来自国营特困老人之家。他因右前足湿性坏疽入院,病情严重。他发展为败血症相关的心肌梗死,需要双重抗血小板药物(氯吡格雷,阿司匹林)。尽管患者处于凝血障碍状态,但仍计划在腘/隐神经阻滞下进行清创/脚趾截肢。方框1:医学指征。消除脓毒症源头,减轻疼痛,无全身麻醉风险。Box2:病人的偏好。当凝血功能障碍并伴有血肿/神经损伤等并发症时,他是否需要局部阻滞手术?由于能力不足,需要紧急手术,麻醉师根据最佳利益/必要性做出决定。专栏3:生活质量。他的病前状态很悲惨,但他目前的状态更糟,因为他在疼痛和化脓。Box4:上下文特征。有一只臭/痛的化脓性坏疽脚是没有尊严的。鉴于患者近期梗死,局部麻醉较全麻安全。并非没有风险,块的外围性质和使用超声波引导使其更安全。结论四盒方法可用于指导凝血障碍患者在无法讨论风险和替代方案的情况下进行神经阻滞的决定。首要考虑的是他的尊严和舒适。附件AbstractJonsen AR.docx
{"title":"#34837 Decision-making framework to undertake regional anaethesia in patients with poor comorbidities and diminished mental capacity","authors":"Tong-Khee Tan","doi":"10.1136/rapm-2023-esra.402","DOIUrl":"https://doi.org/10.1136/rapm-2023-esra.402","url":null,"abstract":"<h3></h3> <b>Please confirm that an ethics committee approval has been applied for or granted:</b> Not relevant (see information at the bottom of this page) <b>Application for ESRA Abstract Prizes:</b> I don’t wish to apply for the ESRA Prizes <h3>Background and Aims</h3> Informed consent forms the cornerstone of regional anaesthesia. In patients lacking mental capacity, risks of a performing a particular regional technique/alternatives would not be able to be conveyed. The decision to use regional techniques may make anaesthetists uncomfortable especially if the incompetent patient has no family members/legal representatives. This poster suggests using Jonsens’s 4box approach(1) to aid anaesthetists’decision-making/justification when using regional techniques in sub-optimal patients. <h3>Methods</h3> 85 year old severely demented Mr.X, bedbound, was from state-run nursing home for destitutes. He was admitted with wet gangrene of right forefoot,in severe distress. He developed a sepsis-related myocardial infarction needing dual anti-platelets(clopidogrel,aspirin). A debridement/toes amputation was planned,under popliteal/saphenous nerve block,despite his coagulopathic state. <h3>Results</h3> Box1:Medical indications. To remove source of sepsis and pain relief, without general anaesthetic risks. Box2:Patient preference. Would he want surgery under regional block when coagulopathic, with complications such as haematoma/nerve injury? Lacking capacity and needing urgent procedure, the anaesthetist made decisions based on best interest/neccesity. Box3:Quality of life. His premorbid state was miserable but his current state worse as he was in pain and septic. Box4:Contextual features. There was no dignity having a smelly/painful septic gangrenous foot. Regional technique was safer than general anaesthetic in view of his recent infarction. Not without risks, the peripheral nature of the block and using ultrasound guidance made it safer. <h3>Conclusions</h3> The four box approach was used to guide decision to perform a nerve block in a coagulopathic patient, who was unable to discuss risks and alternatives. The over-riding consideration acutely was his dignity, comfort. <h3>Attachment</h3> AbstractJonsen AR.docx","PeriodicalId":80519,"journal":{"name":"Archaeologia aeliana, or, Miscellaneous tracts relating to antiquity","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135686273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Archaeologia aeliana, or, Miscellaneous tracts relating to antiquity
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