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Improved intra-atrial conduction delay after successful ablation for atrial fibrillation by scar homogenization in right atrium 通过右心房瘢痕均匀化改善心房颤动消融成功后的心房内传导延迟。
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-10-02 DOI: 10.1111/anec.13091
Jeongduk Seo MD, Yae Min Park MD, PhD, Yong Hoon Shin MD, Albert Youngwoo Jang MD, PhD, Woong Chol Kang MD, PhD, Wook-Jin Chung MD, PhD, Young-Hoon Kim MD, PhD, In Suck Choi MD, PhD

Atrial fibrosis in the right atrium (RA) presenting as a low-voltage zone might be the mechanism of atrial fibrillation (AF) and intra-atrial conduction delay. The impact of scar homogenization in RA on intra-atrial conduction delay is unknown. We describe a patient with paroxysmal AF and significant intra-atrial conduction delay with repetitive atrial flutter, triggered from the lateral free wall in the RA between the significant low-voltage zone and slow conduction area after pulmonary vein isolation. Linear ablation along the trabeculated lateral free wall in the RA to homogenize the scar was successfully performed, and the intra-atrial conduction delay improved ultimately.

右心房(RA)作为低压区的心房纤维化可能是心房颤动(AF)和心房内传导延迟的机制。RA瘢痕均匀化对心房内传导延迟的影响尚不清楚。我们描述了一名阵发性房颤患者,在肺静脉隔离后,由显著低电压区和慢传导区之间的RA侧游离壁触发,并伴有重复性心房扑动的显著心房内传导延迟。成功地沿着RA的小梁侧游离壁进行了线性消融,使瘢痕均匀化,最终改善了心房内传导延迟。
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引用次数: 0
Prognostic significance of the Holter-derived T-wave variability in patients with ventricular tachyarrhythmias complicating acute coronary syndrome—TWIST study 动态心电图T波变异性对室性快速心律失常并发急性冠状动脉综合征患者预后的意义TWIST研究。
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-22 DOI: 10.1111/anec.13069
Taro Makino MD, Tomohide Ichikawa MD, Mari Amino MD, Mari Nakamura MD, Masayuki Koshikawa MD, Yuji Motoike MD, Yoshihiro Nomura MD, Masahide Harada MD, Yoshihiro Sobue MD, Eiichi Watanabe MD, Ken Kiyono PhD, Koichiro Yoshioka MD, Yuji Ikari MD, Yukio Ozaki MD, Hideo Izawa MD

Background

We aimed to investigate the association between ventricular repolarization instability and sustained ventricular tachycardia and ventricular fibrillation (VT/VF) occurring within 48 h (acute-phase VT/VF) after the onset of acute coronary syndrome (ACS) and the prognostic role of repolarization instability and heart rate variability (HRV) after discharge from the hospital.

Methods

We studied 572 ACS patients with a left ventricular ejection fraction >35%. The ventricular repolarization instability was assessed by the beat-to-beat T-wave amplitude variability (TAV) using high-resolution 24-h Holter ECGs recorded at a median of 11 days from the date of admission. We calculated the HRV parameters including the deceleration capacity (DC) and non-Gaussian index calculated on a 25 s timescale (λ25s). The DC and λ25s were dichotomized based on previous studies' thresholds.

Results

Acute-phase VT/VF developed in 43 (7.5%) patients. In-hospital mortality was significantly higher among VT/VF patients (4.7% vs. 0.9%, p = .03). An adjusted logistic model showed that the maximum TAV (odds ratio 1.02, 95% confidence interval [CI] 1.00–1.29, p = .04) was associated with acute-phase VT/VF. During a median follow-up period of 2.1 years, 19 (3.3%) patients had cardiac deaths or resuscitated cardiac arrest. Acute-phase VT/VF (p = .12) and TAV (p = .72) were not significant predictors of survival. An age and sex-adjusted Cox model showed that the DC (p < .01), λ25s (p < .01), and emergency coronary intervention (p < .01) were independent predictors.

Conclusion

T-wave amplitude variability was associated with acute-phase VT/VF, but the TAV was not predictive of survival post-discharge. The DC, λ25s, and emergency coronary intervention were independent predictors of survival.

背景:我们旨在研究心室复极不稳定与48小时内发生的持续性室性心动过速和心室颤动(VT/VF)之间的关系 h(急性期VT/VF)以及出院后复极不稳定性和心率变异性(HRV)的预后作用。方法:我们研究了572例左心室射血分数>35%的ACS患者。心室复极不稳定性是通过使用高分辨率24小时动态心电图(记录在中位数11 天。我们计算了HRV参数,包括减速能力(DC)和在25 s时间尺度(λ25s)。根据先前研究的阈值对DC和λ25s进行二分。结果:43例(7.5%)患者出现急性期VT/VF。VT/VF患者的住院死亡率明显较高(4.7%vs.0.9%,p = .03)。调整后的逻辑模型显示,最大TAV(比值比1.02,95%置信区间[CI]1.00-1.29,p = .04)与急性期VT/VF相关。中位随访期为2.1 年,19名(3.3%)患者出现心脏死亡或复苏性心脏骤停。急性期VT/VF(p = .12) 和TAV(p = .72)不是生存的重要预测因素。年龄和性别调整的Cox模型显示DC(p 结论:T波振幅变异性与急性期VT/VF有关,但TAV不能预测出院后的生存率。DC、λ25s和紧急冠状动脉介入治疗是生存率的独立预测因素。
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引用次数: 0
Increasing averaging beats improves the test accuracy on Holter-based late potentials in patients with myocardial infarction 增加平均搏动可提高心肌梗死患者基于动态心电图的晚电位测试的准确性。
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-19 DOI: 10.1111/anec.13089
Kenichi Hashimoto MD, PhD, ISHNE-F, Naomi Harada MA, Motohiro Kimata MD, Yusuke Kawamura MD, Naoya Fujita MD, Akinori Sekizawa MD, Yosuke Ono MD, PhD, Yasuhiro Obuchi MD, PhD, Tadateru Takayama MD, PhD, Yuji Kasamaki MD, PhD, Yuji Tanaka MD, PhD

Background

The prevalence of Holter-based late potentials (H-LPs) in cases of fatal cardiac events has increased. Although the noise level of H-LP is higher than that of conventional real-time late potential (LP) recording, a procedure to reduce the noise severity in H-LP by increasing the averaging beats has not been investigated.

Methods

We enrolled 104 patients with post-myocardial infarction (MI) and 86 control participants. Among the patients, 30 reported sustained ventricular tachycardia (VT), and the remaining 74 had unrecorded VT. H-LPs were measured twice in all groups to evaluate the efficacy of increasing the averaging beats for H-LPs. Thereafter, the average of LP was calculated at 250 (default setting), 300, 400, 500, 600, 700, and 800 beats.

Results

Across all three groups (MI-VT group, MI non-VT group, and control group), the noise levels significantly decreased in consonance with the increase in averaging beats. In the MI-VT group, the H-LP positive rate considerably increased with the increase in the averaging beats from 250 to 800 both at night and daytime. In the MI-VT group, the LP parameters significantly deteriorated, which led to a positive judgment corresponding to the increment of the averaged night and day beats. The H-LP positive rates were unchanged in the MI non-VT and control groups, while the LP parameters remained consistent, despite the increased averaging beats in the MI non-VT and control groups.

Conclusion

Increasing the calculated averaging beats in H-LPs can improve the sensitivity of predicting fatal cardiac events in patients with MI.

背景:致命心脏事件中基于动态心电图的晚电位(H-LP)的患病率有所上升。尽管H-LP的噪声水平高于传统的实时晚电位(LP)记录的噪声水平,但尚未研究通过增加平均拍频来降低H-LP中噪声严重程度的程序。方法:我们招募了104名心肌梗死后患者和86名对照组参与者。在这些患者中,30例报告了持续性室性心动过速(VT),其余74例报告了未记录的VT。在所有组中测量了两次H-LPs,以评估增加H-LPs平均搏动的疗效。此后,在250(默认设置)、300、400、500、600、700和800拍下计算LP的平均值。结果:在所有三组(MI-VT组、MI非VT组和对照组)中,噪声水平显著降低,与平均心跳的增加一致。在MI-VT组中,H-LP阳性率随着夜间和日间平均搏动从250次增加到800次而显著增加。在MI-VT组中,LP参数显著恶化,这导致了与平均昼夜跳动的增量相对应的积极判断。MI非VT和对照组的H-LP阳性率没有变化,而LP参数保持一致,尽管MI非VT组和对照组平均搏动增加。结论:增加H-LP计算的平均搏动可以提高MI患者预测致命心脏事件的敏感性。
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引用次数: 0
Reassessing the clinical significance of electrocardiographically unrecognized myocardial infarctions: Radionuclide infarct size and its impact on long-term prognosis 重新评估心电图未识别心肌梗死的临床意义:放射性核素梗死大小及其对长期预后的影响
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-14 DOI: 10.1111/anec.13088
Khawaja Afzal Ammar MD, MS, Richard J. Rodeheffer MD

Background

Silent or unrecognized myocardial infarction (UMI) diagnosed by surveillance electrocardiography (ECG) carries similarly poor prognosis as recognized MI (RMI) for poorly understood reasons.

Methods

This study included 5430 consecutive patients who presented to the nuclear laboratory and underwent 2-day stress and rest Tc-99m sestamibi and ECG studies between March 1991 and June 1999. UMI was diagnosed if ECG showed Q-wave MI in the absence of a history of RMI. We measured infarct size (% defect size as compared with the entire left ventricular sestamibi uptake), ejection fraction (EF, %), and summed difference score (SDS, sestamibi uptake by myocardium in stress minus sestamibi uptake in rest images as a marker of ischemia). Survival was determined by follow-up survey (median 6 years).

Results

We identified 346 UMIs, 628 RMIs, and 4456 subjects without MI (No MI). As compared with RMI, UMI patients had lesser abnormalities on nuclear scans (p < .0001 for all), including smaller infarct size (5.7% vs. 12.2%), higher EF (58% vs. 53%), and lesser ischemia (SDS; 3.9% vs. 2.7%). UMI prognosis was as poor as that of RMI (annual mortality rate 4.7% vs. 4.8% with No MI rate of 2.9%; p < .001 for all comparisons), and this persisted after multivariate analysis. Infarct size quantification successfully risk-stratified ECG-UMI patients, but UMI patients continued to predict mortality even if the infarct size was 0%.

Conclusions

Although UMI patients have lesser abnormalities on nuclear scans, ECG-based UMI continues to independently predict mortality, indicating the continuing relevance of ECG in clinical practice.

背景:监测心电图(ECG)诊断的无症状或无法识别的心肌梗死(UMI)与已识别的心肌梗死(RMI)有着相似的不良预后,原因尚不清楚。方法在1991年3月至1999年6月期间,5430例连续到核实验室就诊的患者进行了为期2天的应激休息Tc-99m sestamibi和心电图检查。在没有RMI病史的情况下,如果心电图显示q波MI,则诊断为UMI。我们测量了梗死面积(缺损面积与整个左心室安定比摄取的百分比)、射血分数(EF, %)和总差异评分(SDS,应激状态下心肌安定比摄取减去静止状态下安定比摄取作为缺血标志)。生存率通过随访调查确定(中位6年)。结果我们确定了346名UMIs, 628名RMIs和4456名无MI (No MI)的受试者。与RMI相比,UMI患者在核扫描上的异常较少(p <)。0001),包括较小的梗死面积(5.7%对12.2%),较高的EF(58%对53%)和较小的缺血(SDS;3.9% vs. 2.7%)。UMI预后与RMI一样差(年死亡率4.7% vs. 4.8%,无MI率2.9%;p <001),在多变量分析后,这种情况仍然存在。梗死面积量化成功地对ECG-UMI患者进行了风险分层,但即使梗死面积为0%,UMI患者仍能预测死亡率。尽管UMI患者在核扫描上的异常较小,但基于ECG的UMI仍然可以独立预测死亡率,这表明ECG在临床实践中仍然具有相关性。
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引用次数: 0
Risk assessment of post-myocardial infarction patients with preserved ejection fraction using 45-min short resting Holter electrocardiographic recordings 使用45分钟静息短动态心电图记录保留射血分数的心肌梗死后患者的风险评估
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-12 DOI: 10.1111/anec.13087
Konstantinos Triantafyllou MD, Nikolaos Fragakis MD, PhD, Konstantinos A. Gatzoulis MD, PhD, Antonios Antoniadis MD, PhD, Georgios Giannopoulos MD, PhD, Petros Arsenos MD, PhD, Dimitrios Tsiachris MD, PhD, Christos-Konstantinos Antoniou MD, PhD, Konstantinos Trachanas MD, PhD, Konstantinos Tsimos MD, PhD, Vassilios Vassilikos MD, PhD

Background

Risk stratification for sudden cardiac death in post-myocardial infarction (post-MI) patients remains a challenging task. Several electrocardiographic noninvasive risk factors (NIRFs) have been associated with adverse outcomes and were used to refine risk assessment. This study aimed to evaluate the performance of NIRFs extracted from 45-min short resting Holter ECG recordings (SHR), in predicting ventricular tachycardia inducibility with programmed ventricular stimulation (PVS) in post-MI patients with preserved left ventricular ejection fraction (LVEF).

Methods

We studied 99 post-MI ischemia-free patients (mean age: 60.5 ± 9.5 years, 86.9% men) with LVEF ≥40%, at least 40 days after revascularization. All the patients underwent PVS and a high-resolution SHR. The following parameters were evaluated: mean heart rate, ventricular arrhythmias (premature ventricular complexes, couplets, tachycardias), QTc duration, heart rate variability (HRV), deceleration capacity, heart rate turbulence, late potentials, and T-wave alternans.

Results

PVS was positive in 24 patients (24.2%). HRV, assessed by the standard deviation of normal-to-normal R–R intervals (SDNN), was significantly decreased in the positive PVS group (42 ms vs. 51 ms, p = .039). SDNN values <50 ms were also associated with PVS inducibility (OR 3.081, p = .032 in univariate analysis, and 4.588, p = .013 in multivariate analysis). No significant differences were identified for the other NIRFs. The presence of diabetes, history of ST-elevation MI (STEMI) and LVEF <50% were also important predictors of positive PVS.

Conclusions

HRV assessed from SHR, combined with other noninvasive clinical and echocardiographic variables (diabetes, STEMI history, LVEF), can provide an initial, practical, and rapid screening tool for arrhythmic risk assessment in post-MI patients with preserved LVEF.

背景:心肌梗死后(post-MI)患者心源性猝死的风险分层仍然是一个具有挑战性的任务。一些心电图无创危险因素(nirf)与不良结果相关,并被用于完善风险评估。本研究旨在评估从45分钟短静息动态心电图记录(SHR)中提取的nirf在保留左室射血分数(LVEF)的心肌梗死后患者的程序性心室刺激(PVS)预测室性心动过速诱发性中的作用。方法我们研究了99例心肌梗死后无缺血患者(平均年龄:60.5±9.5岁,86.9%为男性),LVEF≥40%,血运重建术后至少40天。所有患者均行PVS和高分辨率SHR。评估以下参数:平均心率、室性心律失常(室性早搏、室性心律联、心动过速)、QTc持续时间、心率变异性(HRV)、减速能力、心率湍流、晚期电位和t波交替。结果PVS阳性24例(24.2%)。通过正常到正常R-R区间(SDNN)的标准偏差评估,PVS阳性组的HRV显著降低(42 ms vs 51 ms, p = 0.039)。SDNN值<50 ms也与PVS诱导性相关(OR 3.081, p =。单变量分析为0.32,p = 4.588, p =。多变量分析(013)。其他nirf没有发现显著差异。糖尿病的存在、st段抬高性心肌梗死(STEMI)史和LVEF <50%也是PVS阳性的重要预测因素。结论SHR评估HRV,结合其他无创临床和超声心动图变量(糖尿病、STEMI病史、LVEF),可为心肌梗死后保留LVEF患者心律失常风险评估提供初步、实用和快速的筛查工具。
{"title":"Risk assessment of post-myocardial infarction patients with preserved ejection fraction using 45-min short resting Holter electrocardiographic recordings","authors":"Konstantinos Triantafyllou MD,&nbsp;Nikolaos Fragakis MD, PhD,&nbsp;Konstantinos A. Gatzoulis MD, PhD,&nbsp;Antonios Antoniadis MD, PhD,&nbsp;Georgios Giannopoulos MD, PhD,&nbsp;Petros Arsenos MD, PhD,&nbsp;Dimitrios Tsiachris MD, PhD,&nbsp;Christos-Konstantinos Antoniou MD, PhD,&nbsp;Konstantinos Trachanas MD, PhD,&nbsp;Konstantinos Tsimos MD, PhD,&nbsp;Vassilios Vassilikos MD, PhD","doi":"10.1111/anec.13087","DOIUrl":"10.1111/anec.13087","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Risk stratification for sudden cardiac death in post-myocardial infarction (post-MI) patients remains a challenging task. Several electrocardiographic noninvasive risk factors (NIRFs) have been associated with adverse outcomes and were used to refine risk assessment. This study aimed to evaluate the performance of NIRFs extracted from 45-min short resting Holter ECG recordings (SHR), in predicting ventricular tachycardia inducibility with programmed ventricular stimulation (PVS) in post-MI patients with preserved left ventricular ejection fraction (LVEF).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We studied 99 post-MI ischemia-free patients (mean age: 60.5 ± 9.5 years, 86.9% men) with LVEF ≥40%, at least 40 days after revascularization. All the patients underwent PVS and a high-resolution SHR. The following parameters were evaluated: mean heart rate, ventricular arrhythmias (premature ventricular complexes, couplets, tachycardias), QTc duration, heart rate variability (HRV), deceleration capacity, heart rate turbulence, late potentials, and T-wave alternans.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PVS was positive in 24 patients (24.2%). HRV, assessed by the standard deviation of normal-to-normal R–R intervals (SDNN), was significantly decreased in the positive PVS group (42 ms vs. 51 ms, <i>p</i> = .039). SDNN values &lt;50 ms were also associated with PVS inducibility (OR 3.081, <i>p</i> = .032 in univariate analysis, and 4.588, <i>p</i> = .013 in multivariate analysis). No significant differences were identified for the other NIRFs. The presence of diabetes, history of ST-elevation MI (STEMI) and LVEF &lt;50% were also important predictors of positive PVS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>HRV assessed from SHR, combined with other noninvasive clinical and echocardiographic variables (diabetes, STEMI history, LVEF), can provide an initial, practical, and rapid screening tool for arrhythmic risk assessment in post-MI patients with preserved LVEF.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"28 6","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.13087","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10223305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of right bundle branch block or intraventricular conduction delay with recurrence of atrial fibrillation after catheter ablation 导管消融后房颤复发与右束分支阻滞或室内传导延迟的关系
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-10 DOI: 10.1111/anec.13083
Sung Ho Lee MD, PhD, Ji-Hoon Choi MD, Seung-Jung Park MD, PhD, Kyoung-Min Park MD, PhD, June Soo Kim MD, PhD, Young Keun On MD, PhD

Background

The association between bundle branch block (BBB) and recurrence of atrial fibrillation (AF) after catheter ablation is unclear. The aim of this study was to determine whether AF combined with BBB is associated with AF recurrence after catheter ablation.

Methods

A total of 477 consecutive AF patients who underwent catheter ablation were included. The AF patients were divided into three groups according to BBB: AF without BBB (n = 427), AF with right bundle branch block (AF with RBBB) (n = 16), and AF with intraventricular conduction delay (AF with IVCD) (n = 34).

Results

Of the 477 AF patients (mean age 57 years, 81% men, median CHA2DS2-VASc score of 1), 16 (3.4%) patients had RBBB, and 34 (7.1%) patients had IVCD. During a mean follow-up of 15.2 ± 6.7 months, 119 patients (24.9%) had recurrence of AF. Of these, 111 (26%) patients were in the AF without BBB group, with 2 (12.5%) and 6 (17.6%) patients in the RBBB and IVCD groups, respectively. The Kaplan–Meier estimate of the rate of recurrent AF was not significantly different among the three groups (p = .39). Multivariable analysis showed that persistent AF (HR 1.7, 95% CI 1.15–2.50, p = .007), chronic kidney disease (HR 2.94, 95% CI 1.20–7.17, p = .01), and left atrial diameter (HR 1.04, 95% CI 1.009–1.082, p = .01) were significantly associated with AF recurrence.

Conclusion

AF with BBB was not significantly associated with the recurrence of AF after catheter ablation in middle-aged patients with low-risk cardiovascular profile.

背景:束支阻滞(BBB)与导管消融后房颤(AF)复发的关系尚不清楚。本研究的目的是确定房颤合并血脑屏障是否与导管消融后房颤复发有关。方法连续477例房颤患者行导管消融治疗。根据血脑屏障情况将房颤患者分为3组:无血脑屏障房颤(n = 427)、右束支阻滞房颤(n = 16)、室内传导延迟房颤(n = 34)。结果477例房颤患者(平均年龄57岁,81%为男性,CHA2DS2-VASc中位评分为1),16例(3.4%)患者有RBBB, 34例(7.1%)患者有IVCD。在平均15.2±6.7个月的随访中,有119例(24.9%)患者发生房颤复发,其中无血凝血组111例(26%),RBBB组2例(12.5%),IVCD组6例(17.6%)。Kaplan-Meier估计的房颤复发率在三组间无显著差异(p = 0.39)。多变量分析显示,持续性房颤(HR 1.7, 95% CI 1.15-2.50, p = 0.007)、慢性肾脏疾病(HR 2.94, 95% CI 1.20-7.17, p = 0.01)和左房内径(HR 1.04, 95% CI 1.009-1.082, p = 0.01)与房颤复发显著相关。结论中年低危心血管患者房颤伴血脑梗死与房颤消融后复发无显著相关性。
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引用次数: 0
Mayo Clinic VT calculator: A practical tool for accurate wide complex tachycardia differentiation 梅奥诊所VT计算器:一个实用的工具,准确的宽复杂心动过速分化
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-05 DOI: 10.1111/anec.13085
Anthony H. Kashou MD, Sarah LoCoco MD, Matthew R. Gardner MBA, MDes, Jocelyn Webb BS, Jacob C. Jentzer MD, Peter A. Noseworthy MD, Christopher V. DeSimone MD, PhD, Abhishek J. Deshmukh MBBS, Samuel J. Asirvatham MD, Adam M. May MD

The discrimination of ventricular tachycardia (VT) versus supraventricular wide complex tachycardia (SWCT) via 12-lead electrocardiogram (ECG) is crucial for achieving appropriate, high-quality, and cost-effective care in patients presenting with wide QRS complex tachycardia (WCT). Decades of rigorous research have brought forth an expanding arsenal of applicable manual algorithm methods for differentiating WCTs. However, these algorithms are limited by their heavy reliance on the ECG interpreter for their proper execution. Herein, we introduce the Mayo Clinic ventricular tachycardia calculator (MC-VTcalc) as a novel generalizable, accurate, and easy-to-use means to estimate VT probability independent of ECG interpreter competency. The MC-VTcalc, through the use of web-based and mobile device platforms, only requires the entry of computerized measurements (i.e., QRS duration, QRS axis, and T-wave axis) that are routinely displayed on standard 12-lead ECG recordings.

通过12导联心电图(ECG)区分室性心动过速(VT)与室上宽性复杂心动过速(SWCT)对于获得对宽QRS复杂心动过速(WCT)患者的适当、高质量和高成本效益的护理至关重要。几十年的严格研究已经提出了一个适用于区分wct的手动算法方法的扩展库。然而,这些算法由于其对ECG解释器的严重依赖而受到限制。在此,我们介绍了梅奥诊所室性心动过速计算器(MC-VTcalc),作为一种新颖的、通用的、准确的、易于使用的方法来估计VT概率,而不依赖于ECG口译能力。MC-VTcalc通过使用基于网络和移动设备平台,只需要输入计算机化的测量值(即QRS持续时间,QRS轴和t波轴),这些测量值通常显示在标准的12导联心电图记录上。
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引用次数: 0
A large population-based study on the prevalence of electrocardiographic abnormalities: A result of Mashhad stroke and heart atherosclerotic disorder cohort study 一项基于人群的心电图异常患病率研究:马什哈德卒中和心脏动脉粥样硬化性疾病队列研究结果
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-03 DOI: 10.1111/anec.13086
Sara Saffar Soflaei MD, PhD, Mahmoud Ebrahimi MD, Hamid Reza Rahimi MD, PhD, AmirAli Moodi Ghalibaf MD, Maryam Jafari MD, Hedieh Alimi MD, Nasrin Talkhi MSc, Bahram Shahri MD, Alireza Heidari-Bakavoli MD, Fatemeh Malakouti, Mahla Velayati, Reza Assaran-Darban PhD, Malihehsadat Abedsaeidi MSc, Farnoosh Azarian MSc, MohammadReza Latifi MSc, Mohammad Reza Mohammad Taghizadeh Sarabi MSc, Gordon A. Ferns MD, PhD, Habibollah Esmaily PhD, Mohsen Moohebati MD, Majid Ghayour-Mobarhan MD, PhD

Background

Twelve-lead electrocardiogram (ECG) is a common and inexpensive tool for the diagnostic workup of patients with suspected cardiovascular disease, both in clinical and epidemiological settings. The present study was designed to evaluate ECG abnormalities in Mashhad population.

Methods

ECGs were taken as part of MASHAD cohort study (phase1) and were coded according to the Minnesota coding criteria. Data were analyzed using SPSS.

Results

Total 9035 ECGs were available for final analysis including 3615 (40.0%) male and 5420 (60.0%) female. Among ECG abnormalities precordial Q wave, major T-wave abnormalities, inferior Q wave, sinus bradycardia, and left axis deviation were the most prevalent abnormalities. The frequency of precordial and inferior Q wave, inferior QS pattern, major and minor ST abnormalities, major and minor T abnormalities, Wolff-Parkinson-White and Brugada pattern, sinus bradycardia, sinus tachycardia, left axis deviation, ST elevation, and tall T wave were significantly different between two genders. Moreover, the frequency of Q wave in precordial and aVL leads, QS pattern in precordial and inferior leads, major and minor T-wave abnormalities, Wolff-Parkinson-White, atrial fibrillation, sinus bradycardia, left axis deviation, and ST elevation were significantly different in different age groups. A comparison of the heart rate, P-wave duration, and QRS duration between men and women indicated that there was a significant difference.

Conclusions

Our finding indicated that the prevalence ECG abnormalities are different between men and women and also it varied in different age groups.

背景十二导联心电图(ECG)是临床和流行病学背景下对疑似心血管疾病患者进行诊断检查的一种常见且廉价的工具。本研究旨在评估马什哈德人群的心电图异常。方法将心电图作为MASHAD队列研究(第一阶段)的一部分,按照明尼苏达州编码标准进行编码。数据采用SPSS进行分析。结果共收集心电图9035张,其中男性3615张(40.0%),女性5420张(60.0%)。心电图异常中以心前Q波、主t波、下Q波、窦性心动过缓、左心轴偏曲最为常见。心前、下Q波、下QS型、轻重ST异常、轻重T异常、Wolff-Parkinson-White和Brugada型、窦性心动过缓、窦性心动过速、左轴偏移、ST抬高、高T波频率在两性间存在显著差异。此外,心前导联和aVL导联的Q波频率、心前导联和下导联的QS型、主要t波和次要t波异常、Wolff-Parkinson-White、心房颤动、窦性心动过缓、左轴偏曲、ST段抬高在不同年龄组间存在显著差异。男女之间的心率、p波持续时间和QRS持续时间的比较表明存在显著差异。结论心电异常的发生率在男女之间存在差异,在不同年龄组之间也存在差异。
{"title":"A large population-based study on the prevalence of electrocardiographic abnormalities: A result of Mashhad stroke and heart atherosclerotic disorder cohort study","authors":"Sara Saffar Soflaei MD, PhD,&nbsp;Mahmoud Ebrahimi MD,&nbsp;Hamid Reza Rahimi MD, PhD,&nbsp;AmirAli Moodi Ghalibaf MD,&nbsp;Maryam Jafari MD,&nbsp;Hedieh Alimi MD,&nbsp;Nasrin Talkhi MSc,&nbsp;Bahram Shahri MD,&nbsp;Alireza Heidari-Bakavoli MD,&nbsp;Fatemeh Malakouti,&nbsp;Mahla Velayati,&nbsp;Reza Assaran-Darban PhD,&nbsp;Malihehsadat Abedsaeidi MSc,&nbsp;Farnoosh Azarian MSc,&nbsp;MohammadReza Latifi MSc,&nbsp;Mohammad Reza Mohammad Taghizadeh Sarabi MSc,&nbsp;Gordon A. Ferns MD, PhD,&nbsp;Habibollah Esmaily PhD,&nbsp;Mohsen Moohebati MD,&nbsp;Majid Ghayour-Mobarhan MD, PhD","doi":"10.1111/anec.13086","DOIUrl":"10.1111/anec.13086","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Twelve-lead electrocardiogram (ECG) is a common and inexpensive tool for the diagnostic workup of patients with suspected cardiovascular disease, both in clinical and epidemiological settings. The present study was designed to evaluate ECG abnormalities in Mashhad population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>ECGs were taken as part of MASHAD cohort study (phase1) and were coded according to the Minnesota coding criteria. Data were analyzed using SPSS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Total 9035 ECGs were available for final analysis including 3615 (40.0%) male and 5420 (60.0%) female. Among ECG abnormalities precordial Q wave, major T-wave abnormalities, inferior Q wave, sinus bradycardia, and left axis deviation were the most prevalent abnormalities. The frequency of precordial and inferior Q wave, inferior QS pattern, major and minor ST abnormalities, major and minor T abnormalities, Wolff-Parkinson-White and Brugada pattern, sinus bradycardia, sinus tachycardia, left axis deviation, ST elevation, and tall T wave were significantly different between two genders. Moreover, the frequency of Q wave in precordial and aVL leads, QS pattern in precordial and inferior leads, major and minor T-wave abnormalities, Wolff-Parkinson-White, atrial fibrillation, sinus bradycardia, left axis deviation, and ST elevation were significantly different in different age groups. A comparison of the heart rate, P-wave duration, and QRS duration between men and women indicated that there was a significant difference.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Our finding indicated that the prevalence ECG abnormalities are different between men and women and also it varied in different age groups.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8074,"journal":{"name":"Annals of Noninvasive Electrocardiology","volume":"28 6","pages":""},"PeriodicalIF":1.9,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/anec.13086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10518924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Left ventricular noncompaction cardiomyopathy and short QT syndrome due to primary carnitine deficiency 原发性肉碱缺乏引起的左室非压实性心肌病和短QT综合征
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-09-01 DOI: 10.1111/anec.13077
Oliver P. Hanington MRCP, Catherine Armstrong MRCPCH, Germaine Pierre MRCPCH, Graham Stuart FRCP, Jules C. Hancox DSc, FRSB, FBPhS

We report the case of a 13-year-old female patient presenting with presyncope and palpitations. Her electrocardiogram revealed an abbreviation of the rate-corrected QT interval with imaging showing significant left ventricular dysfunction. Carnitine levels were measured as part of her diagnostic workup, discovering a rare, reversible cause of short QT syndrome (SQTS) and associated cardiomyopathy—primary carnitine deficiency (PCD) caused by a homozygous mutation in the SLC22A5 gene, leading to an in-frame deletion mutation (NP_003051.1:p.Phe23del) affecting the organic cation transporter 2 (OCTN2) protein. Following the treatment with oral carnitine supplementation, her QT interval returned to within the normal range with significant improvement in left ventricular function.

我们报告的情况下,13岁的女性患者提出晕厥前和心悸。她的心电图显示经速率校正的QT间期缩短,影像学显示明显的左心室功能障碍。作为她的诊断检查的一部分,测量了肉碱水平,发现了一种罕见的,可逆的短QT综合征(SQTS)和相关心肌病-原发性肉碱缺乏症(PCD)的原因,这是由SLC22A5基因的纯合突变引起的,导致框内缺失突变(NP_003051.1:p.Phe23del)影响有机阳离子转运体2 (OCTN2)蛋白。经口服肉碱治疗后,QT间期恢复正常,左室功能明显改善。
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引用次数: 0
Outcomes of primary leadless pacemaker implantation: A systematic review 初级无铅起搏器植入的结果:一项系统综述
IF 1.9 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2023-08-22 DOI: 10.1111/anec.13084
Tayyiba Ahmed Noor MBBS, Muhammad Omer Rehman Rana MBBS, Sapna Kumari MBBS, Bakht Umer MBBS, Jahanzeb Malik MBBS, Amna Ashraf MBBS, Maria Faraz MBBS, Tabligh Hussain MBBS, Muhammad Awais MBBS, Amin Mehmoodi MD, Azmat Hayat MBBS

Background

During the last decade, leadless pacemakers (LPMs) have turned into a prevalent alternative to traditional transvenous (TV) pacemakers; however, there is no consolidated data on LPM implantation in emergencies.

Methods

Digital databases were searched for this review and four relevant studies, including 1276 patients were included in this review with procedure duration, fluoroscopic time, major complications, and mortality as primary outcomes and pacing threshold, impedance, sensing of LPM, and hospital stay as secondary outcomes.

Results

Gonzales et al. and Marschall et al. showed the duration of the procedure to be 180 ± 45 versus 324.6 ± 92 and 39.9 ± 8.7 versus 54.9 ± 9.8, respectively. Zhang et al. demonstrated the duration of the procedure and fluoroscopy time to be 36 ± 13.4 and 11.1 ± 3.1, respectively. Similarly, Schiavone et al. exhibited intermediate times of implantation at 60 (45–80) versus 50 (40–65) and fluoroscopic times at 6.5 (5–9.7) versus 5.1 (3.1–9). Hospital stay was more with a temp-perm pacemaker as compared to LPM and pacing parameters were not significantly different in all the studies.

Conclusion

For underlying arrhythmias, whenever appropriate, our review shows that LPMs may be a better option than temporary pacemakers, even as an urgent treatment.

在过去的十年中,无导线起搏器(lpm)已经成为传统经静脉(TV)起搏器的普遍替代方案;然而,没有关于紧急情况下LPM植入的综合数据。方法检索数字数据库,纳入本综述和4项相关研究,共纳入1276例患者,以手术时间、透视时间、主要并发症和死亡率为主要结局,以起搏阈值、阻抗、LPM感知和住院时间为次要结局。Gonzales et al.和Marschall et al.分别显示手术持续时间为180±45对324.6±92和39.9±8.7对54.9±9.8。Zhang等人证实手术时间和透视时间分别为36±13.4和11.1±3.1。同样,Schiavone等人的植入中间次数为60(45-80)和50(40-65),透视次数为6.5(5-9.7)和5.1(3.1-9)。与LPM相比,使用恒温起搏器的住院时间更长,起搏参数在所有研究中均无显著差异。结论:对于潜在的心律失常,无论何时,我们的综述显示lpm可能是比临时起搏器更好的选择,即使是作为紧急治疗。
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引用次数: 0
期刊
Annals of Noninvasive Electrocardiology
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