Pub Date : 2023-01-26DOI: 10.21608/ajnsa.2022.156600.1627
Noura Marrouf Arafa, Eman H. Kandil, D. Ibrahim, A. Nada, Nour El-Din A Mohammed
.
{"title":"Modulatory impact of Ebselen against Diethylnitrosamine initiated Hepatocarcinogenesis in rats.","authors":"Noura Marrouf Arafa, Eman H. Kandil, D. Ibrahim, A. Nada, Nour El-Din A Mohammed","doi":"10.21608/ajnsa.2022.156600.1627","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.156600.1627","url":null,"abstract":".","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41725144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-26DOI: 10.21608/ajnsa.2022.160849.1631
Laith Najam, Karam Abd Al- Aziz, M. Hamood
{"title":"Gamma Radiation Absorption Of (Al ,Cu, Pb) Alloys","authors":"Laith Najam, Karam Abd Al- Aziz, M. Hamood","doi":"10.21608/ajnsa.2022.160849.1631","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.160849.1631","url":null,"abstract":"","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47365792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-26DOI: 10.21608/ajnsa.2023.170144.1651
Jamal M. AL-Shareef, R. Elgebaly, E. Attalla, N. Deiab, Dalal Aqmar, Mohamed Fathy
In-vivo dosimetry (IVD) is one of the most accurate ways for determining the dosage provided to the patient during treatment . The aim of this work is to verify whether patients were receiving the accurate prescribed dose. Which occurs by assessing the dose delivery errors, caused by human or equipment malfunctioning, using in-vivo diode dosimetry (IVDD). In total, 302 fields were performed for 80 cases, including pelvis, abdomen, thorax, and head and neck (H & N) patients. Prior to the clinical application, Alderson Rando phantom was used to evaluate the diodes' dependability as a complement to the validation process. The results revealed that the measured dose of the phantom was within ±5% of the planned dose. Additionally, patients' doses achieved 91.4% of the measured dose were within ±5% of the planned dose. Of the other 8.6%, about 5.6 % of the measured doses were more than 5% and less than 10% and only 3% were larger than 10% of the planned dose. The outlying values that were more than 5% were repeated as in-vitro measurements on a phantom and the deviations were within ±5%. This study demonstrated that diode measurements provide an immediate readout during the treatment process and it is reliable as quality assurance for linear accelerator. Moreover, IVDD is capable of detecting major and common treatment errors such as patient setup errors and incorrect source surface distance.
{"title":"An insight on using in-vivo diode dosimetry to verify the delivered doses during radiotherapy","authors":"Jamal M. AL-Shareef, R. Elgebaly, E. Attalla, N. Deiab, Dalal Aqmar, Mohamed Fathy","doi":"10.21608/ajnsa.2023.170144.1651","DOIUrl":"https://doi.org/10.21608/ajnsa.2023.170144.1651","url":null,"abstract":"In-vivo dosimetry (IVD) is one of the most accurate ways for determining the dosage provided to the patient during treatment . The aim of this work is to verify whether patients were receiving the accurate prescribed dose. Which occurs by assessing the dose delivery errors, caused by human or equipment malfunctioning, using in-vivo diode dosimetry (IVDD). In total, 302 fields were performed for 80 cases, including pelvis, abdomen, thorax, and head and neck (H & N) patients. Prior to the clinical application, Alderson Rando phantom was used to evaluate the diodes' dependability as a complement to the validation process. The results revealed that the measured dose of the phantom was within ±5% of the planned dose. Additionally, patients' doses achieved 91.4% of the measured dose were within ±5% of the planned dose. Of the other 8.6%, about 5.6 % of the measured doses were more than 5% and less than 10% and only 3% were larger than 10% of the planned dose. The outlying values that were more than 5% were repeated as in-vitro measurements on a phantom and the deviations were within ±5%. This study demonstrated that diode measurements provide an immediate readout during the treatment process and it is reliable as quality assurance for linear accelerator. Moreover, IVDD is capable of detecting major and common treatment errors such as patient setup errors and incorrect source surface distance.","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46735369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-26DOI: 10.21608/ajnsa.2022.163538.1639
M. Sanad, F. Marzook, S. Challan, H. Essam, A. Farag
Ulcerative colitis (UC) is a chronic, regressive natural disease. The use of conventional diagnostic procedures such as magnetic resonance imaging, ultrasonography, and X-rays during the dormant and early stages of the disease does not aid in diagnosing the disease. As a result, a novel design, such as labelled compounds, were used to image ulcerative colitis disease. In this study, olsalazine was labeled with [ 125/131 I] and the labelling parameters were adjusted to obtain a high radiochemical yield (98.5%). In addition, the olsalazine radiotracer gave 96.0% purity in rate serum for up to twelve hours before it started to degrade at twenty-four hours, and it was stable also, in saline for up to twenty-four hours. Molecular docking was used to assess a complex's affinity for its biological target, and the PPAR receptor. The biological assessment was also performed in mice models of both standard and ulcerative colitis. The results demonstrated that [ 125/131 I] iodoolsalazine had a high uptake of 79.5% (ID/g) at 120 minutes post-injection and is still high to 77% at 24 hours. So, the labelled compound, [ 125/131 I] iodoolsalazine, could be considered a new potential selective radiotracer for preclinical diagnostic research of ulcerative colitis.
{"title":"Radioiodination, and Biological Assessment of Olsalazine, as a Highly Selective Radiotracer for Ulcerative Colitis Imaging in Mice","authors":"M. Sanad, F. Marzook, S. Challan, H. Essam, A. Farag","doi":"10.21608/ajnsa.2022.163538.1639","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.163538.1639","url":null,"abstract":"Ulcerative colitis (UC) is a chronic, regressive natural disease. The use of conventional diagnostic procedures such as magnetic resonance imaging, ultrasonography, and X-rays during the dormant and early stages of the disease does not aid in diagnosing the disease. As a result, a novel design, such as labelled compounds, were used to image ulcerative colitis disease. In this study, olsalazine was labeled with [ 125/131 I] and the labelling parameters were adjusted to obtain a high radiochemical yield (98.5%). In addition, the olsalazine radiotracer gave 96.0% purity in rate serum for up to twelve hours before it started to degrade at twenty-four hours, and it was stable also, in saline for up to twenty-four hours. Molecular docking was used to assess a complex's affinity for its biological target, and the PPAR receptor. The biological assessment was also performed in mice models of both standard and ulcerative colitis. The results demonstrated that [ 125/131 I] iodoolsalazine had a high uptake of 79.5% (ID/g) at 120 minutes post-injection and is still high to 77% at 24 hours. So, the labelled compound, [ 125/131 I] iodoolsalazine, could be considered a new potential selective radiotracer for preclinical diagnostic research of ulcerative colitis.","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42116869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/ajnsa.2022.170999.1655
Amir Tolba
{"title":"Using Systematic Analysis for Stealth Elements Against Intrusion of Research Reactors","authors":"Amir Tolba","doi":"10.21608/ajnsa.2022.170999.1655","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.170999.1655","url":null,"abstract":"","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44683830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/ajnsa.2022.144473.1597
Mohamed Ahmed, Farouk Abd El-Rahman
{"title":"Legal Frame of Nuclear and Radiological Programs in Generals And the Egyptians Programs in Special Part1. Nuclear and Radiological Programs in Generals","authors":"Mohamed Ahmed, Farouk Abd El-Rahman","doi":"10.21608/ajnsa.2022.144473.1597","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.144473.1597","url":null,"abstract":"","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44819830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/ajnsa.2022.171880.1661
Philip DORDOH-GASU
{"title":"Ageing Management Activities at the Ghana Research Reactor-1 Facility","authors":"Philip DORDOH-GASU","doi":"10.21608/ajnsa.2022.171880.1661","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.171880.1661","url":null,"abstract":"","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48308748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/ajnsa.2022.171878.1659
Hilda Mpakany, Victor Mutava
{"title":"The Role of Research Reactors in Sustainable Development in Kenya","authors":"Hilda Mpakany, Victor Mutava","doi":"10.21608/ajnsa.2022.171878.1659","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.171878.1659","url":null,"abstract":"","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43831563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.21608/ajnsa.2022.171655.1658
K. Ali
{"title":"Results of the Hydraulic Testing of the New Low Enriched Core of Tajoura Research Reactor","authors":"K. Ali","doi":"10.21608/ajnsa.2022.171655.1658","DOIUrl":"https://doi.org/10.21608/ajnsa.2022.171655.1658","url":null,"abstract":"","PeriodicalId":8110,"journal":{"name":"Arab Journal of Nuclear Sciences and Applications","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41812074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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