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Mini-PCNL – a boon for CKD patients with nephrolithiasis Mini-PCNL - 肾炎 CKD 患者的福音
IF 1.5 Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-12-26 DOI: 10.1080/20905998.2023.2295041
Faiz Manzar Ansari, Sajad Ahmad Para, Mohammad Saleem Wani, A. Bhat, Abdul Rouf Khawaja, S. Malik, Saqib Mehdi, Waseem Ashraf, Shashank Singh, M. Maurya, Aamir Mushtaq
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引用次数: 0
Sixth edition of the World Health Organization laboratory manual of semen analysis: Updates and essential take away for busy clinicians 世界卫生组织精液分析实验室手册第六版:为繁忙的临床医生提供最新信息和必备资料
IF 1.5 Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-12-25 DOI: 10.1080/20905998.2023.2298048
Eric Chung, W. Atmoko, R. Saleh, R. Shah, Ashok Agarwal
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引用次数: 0
Varicocele and male infertility conundrum: Making sense of a never-ending story for the busy clinician 精索静脉曲张和男性不育的难题:让忙碌的临床医生了解永无止境的故事
IF 1.5 Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-12-07 DOI: 10.1080/20905998.2023.2291628
P. Kavoussi, P. Birowo, R. Saleh, R. Shah, Ashok Agarwal
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引用次数: 0
Combined on-demand sildenafil citrate and tramadol hydrochloride is an effective and safe treatment for premature ejaculation: A randomized placebo-controlled double-blind clinical trial 枸橼酸西地那非和盐酸曲马多联合按需治疗早泄既有效又安全:随机安慰剂对照双盲临床试验
IF 1.5 Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-11-30 DOI: 10.1080/20905998.2023.2287869
Ahmed Reda, Adel A Kurkar, Mahmoud Mohamad Shalaby, Mohammed Abdelhafez, Mahmoud Osman, Sherif Abulsorour
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引用次数: 0
Sperm DNA fragmentation in male infertility: From bench to bedside 男性不育的精子DNA断裂:从实验到临床
Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-11-12 DOI: 10.1080/20905998.2023.2278200
Ala’a Farkouh, Ramadan Saleh, Rupin Shah, Ashok Agarwal
Objectives Sperm DNA fragmentation (SDF) is a molecular marker of sperm chromatin health. Elevated SDF is associated with male infertility, recurrent pregnancy loss, and failure of assisted reproductive technologies (ART). In 2021, the sixth edition of the World Health Organization (WHO) Manual for the Laboratory Examination and Processing of Human Semen has listed SDF as an extended test of semen that can be ordered under certain circumstances. However, the manual neither explained the indications for testing nor provided clear guidance on diagnostic thresholds.
目的精子DNA断裂(SDF)是精子染色质健康状况的分子标志物。SDF升高与男性不育、复发性流产和辅助生殖技术(ART)失败有关。2021年,世界卫生组织(世卫组织)第六版《人类精液实验室检查和处理手册》将SDF列为在某些情况下可订购的精液扩展检测。然而,该手册既没有解释检测的适应症,也没有提供诊断阈值的明确指导。
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引用次数: 0
Prospective comparison of tadalafil 5 mg, dapoxetine 30 mg, and the combination of both in the treatment of premature ejaculation 他达拉非5mg、达泊西汀30mg及两者联合治疗早泄的前瞻性比较
Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-11-06 DOI: 10.1080/20905998.2023.2277081
Ahmed Mahmoud Hasan, Mohammed Sayed Abdelkader, Mostafa AbdelRazek Ahmed, Mahmoud Mohsen Mohammed, Gamal Abdelhamid Alsaghier
Objective To compare the efficacy of tadalafil alone, dapoxetine alone, and tadalafil with dapoxetine as a combination therapy for the treatment of premature ejaculation.
目的比较他达拉非单用、达泊西汀单用及他达拉非联用达泊西汀治疗早泄的疗效。
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引用次数: 0
Comparing the risk factors of nephrolithiasis in Asian countries population: A systematic review and meta-analysis 比较亚洲国家人群肾结石的危险因素:系统回顾和荟萃分析
Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-10-16 DOI: 10.1080/20905998.2023.2254960
Zulfikar Ali, Reginald Rustandi, Mohammad Sulchan, Ponco Birowo, Tri Indah Winarni
This systematic review and meta-analysis aims to identify the main risk factors for nephrolithiasis in Asian populations, with comparisons to European and American populations. Using a comprehensive literature search across PubMed, Science Direct, and ResearchGate, in accordance with the Preferred Reporting Items of Systematic reviews and Meta-Analysis (PRISMA) guidelines, we synthesized data from 11 geographically diverse studies. Our findings reveal substantial population-specific differences in nephrolithiasis risk factors, particularly familial history, water consumption, and smoking patterns. In Asian populations, a 60% increase in risk was associated with a family history of nephrolithiasis. In the meantime, drinking sources also affected nephrolithiasis risk, with the consumption of boiled water being associated with a 25% increase in risk compared to consumption of bottled or mineral water. These findings highlight the importance of tailoring preventive strategies and treatments to specific risk factors, taking into account regional variations, and call for additional research to understand the complex interaction between genetic, environmental, and lifestyle factors in the development of nephrolithiasis.
本系统综述和荟萃分析旨在确定亚洲人群肾结石的主要危险因素,并与欧洲和美国人群进行比较。根据系统评价和荟萃分析(PRISMA)指南的首选报告项目,我们对PubMed、Science Direct和ResearchGate进行了全面的文献检索,综合了11项地理上不同的研究的数据。我们的研究结果揭示了肾结石风险因素在人群特异性方面的巨大差异,特别是家族史、饮水量和吸烟模式。在亚洲人群中,60%的风险增加与肾结石家族史有关。与此同时,饮用水源也影响肾结石的风险,与饮用瓶装水或矿泉水相比,饮用开水的风险增加了25%。这些发现强调了针对特定风险因素定制预防策略和治疗的重要性,同时考虑到区域差异,并呼吁进一步研究以了解肾结石发展中遗传、环境和生活方式因素之间复杂的相互作用。
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引用次数: 0
Predicting stone free rate after retrograde intrarenal surgery using RIRS scoring system versus Resorlu Unsal stone score (RUSS) 应用RIRS评分系统与reslu - Unsal结石评分(RUSS)对比预测逆行肾内手术后结石清除率
Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-10-16 DOI: 10.1080/20905998.2023.2252227
Basheer N. Elmohamady, Mahmoud M. Farag, Hamouda W. Sherif, Ahmed EL Ghobashy, Mohamed A. AL Hefnawy
Background To evaluate the predictive ability of the RIRS scoring system and the RUSS in predicting stone-free rate (SFR) after retrograde intrarenal surgery (RIRS).
目的评价RIRS评分系统和RUSS对逆行肾内手术(RIRS)后无结石率(SFR)的预测能力。
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引用次数: 0
Novel urine-based DNA methylation biomarkers for urothelial bladder carcinoma detection in patients with hematuria 血尿患者尿路上皮性膀胱癌检测的新型尿液DNA甲基化生物标志物
Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-05-14 DOI: 10.1080/2090598x.2023.2208492
Hassan F. Abol-Elnazer, Amira Awadalla, Asmaa E. Ahmed, Hassan Abol-Enein, Munir Ali Al Ganzouri, Amr A. Elsawy
Background Urothelial bladder carcinoma (UBC) is usually detected during work-up for hematuria. Cystoscopy and/or contrast-enhanced imaging are the gold standard tools for UBC diagnosis, despite limited by being invasive, expensive and low yield in small flat tumors.Objectives To assess the diagnostic performance of urine-based DNA methylation of six genes (GATA4, P16, P14, APC, CDH1 and CD99) for UBC detection in patients with hematuria.Patients and methods Voided urine was collected from consecutive patients presented with hematuria for urine cytology and DNA methylation assay of the assigned genes using methylation-specific Polymerase Chain Reaction (PCR). Further assessment by office cystoscopy and imaging with subsequent inpatient cystoscopic biopsy for positive findings was done. The diagnostic characteristics of DNA methylation and urine cytology were assessed based on its capability to predict UBC.Results We included 246 patients in the study with identified macroscopic hematuria in 204 (82.9%) patients. Positive cytology was found in 78 (31.7%) patients. DNA methylation of GATA4, P16, P14, APC, CDH1 and CD99 genes was identified in 127 (51.6%), 52 (21.1%), 117 (47.6%), 106 (43.1%), 90 (36.6%) and 71 (28.9%) patients, respectively. The sensitivity of the assigned genes for UBC detection ranges from 35% (95%CI: 31–39) to 83% (95%CI: 79–87). Optimal specificity (SP) (100%) was noted for P16, APC and CDH1 genes. While for the other genes (GATA4, P14 and CD99), the SP was 95% (95%CI: 92–98), 96% (95%CI: 92–99) and 97% (95%CI: 93–99), respectively. On multivariate logistic regression analysis, all genes exclusively demonstrated independent prediction of UBC. On receiver operator characteristic (ROC) analysis, all tested genes methylation showed superior area under the curve (AUC) when compared to urine cytology.Conclusions We have developed a novel urine-based DNA methylation assay for detection of UBC in patients with hematuria with superior diagnostic performance and independent predictive capacity over urine cytology.
背景尿路上皮性膀胱癌(UBC)通常在血尿检查中被发现。膀胱镜检查和/或对比增强成像是UBC诊断的金标准工具,尽管在小的扁平肿瘤中存在侵入性、昂贵和低收益的限制。目的评价尿中6个基因(GATA4、P16、P14、APC、CDH1和CD99) DNA甲基化对血尿患者UBC检测的诊断价值。患者和方法收集连续出现血尿的患者的空尿,进行尿细胞学检查,并采用甲基化特异性聚合酶链反应(methyl- specific Polymerase Chain Reaction, PCR)对指定基因进行DNA甲基化检测。通过办公室膀胱镜检查和成像以及随后的住院膀胱镜活检来进一步评估阳性结果。DNA甲基化和尿细胞学的诊断特点是基于其预测UBC的能力进行评估。结果我们纳入了246例患者,其中204例(82.9%)患者肉眼可见血尿。细胞学阳性78例(31.7%)。GATA4、P16、P14、APC、CDH1和CD99基因甲基化分别在127例(51.6%)、52例(21.1%)、117例(47.6%)、106例(43.1%)、90例(36.6%)和71例(28.9%)患者中检测到。指定基因检测UBC的灵敏度范围为35% (95%CI: 31-39)至83% (95%CI: 79-87)。P16、APC和CDH1基因的最佳特异性(SP)为100%。其他基因GATA4、P14和CD99的SP分别为95% (95% ci: 92 ~ 98)、96% (95% ci: 92 ~ 99)和97% (95% ci: 93 ~ 99)。多因素logistic回归分析显示,所有基因均能独立预测UBC。在受试者操作特征(ROC)分析中,与尿细胞学相比,所有测试基因甲基化显示出优越的曲线下面积(AUC)。我们开发了一种新的基于尿液的DNA甲基化检测方法,用于血尿患者的UBC检测,具有优于尿细胞学的诊断性能和独立预测能力。
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引用次数: 0
Authors' response:Vitamin D supplementation for improving sperm parameters in infertile men: A systematic review and meta-analysis of randomized clinical trials. 作者回应:补充维生素D改善不育男性精子参数:随机临床试验的系统综述和荟萃分析
IF 1.3 Q3 UROLOGY & NEPHROLOGY Pub Date : 2023-04-26 eCollection Date: 2023-01-01 DOI: 10.1080/2090598X.2023.2203605
Clarissa Tania, Edwin Raja Pardamean Lumban Tobing, Christiano Tansol, Patricia Diana Prasetiyo, Caesar Khairul Wallad, Timotius Ivan Hariyanto
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引用次数: 0
期刊
Arab Journal of Urology
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