Pub Date : 2023-12-26DOI: 10.1080/20905998.2023.2295041
Faiz Manzar Ansari, Sajad Ahmad Para, Mohammad Saleem Wani, A. Bhat, Abdul Rouf Khawaja, S. Malik, Saqib Mehdi, Waseem Ashraf, Shashank Singh, M. Maurya, Aamir Mushtaq
{"title":"Mini-PCNL – a boon for CKD patients with nephrolithiasis","authors":"Faiz Manzar Ansari, Sajad Ahmad Para, Mohammad Saleem Wani, A. Bhat, Abdul Rouf Khawaja, S. Malik, Saqib Mehdi, Waseem Ashraf, Shashank Singh, M. Maurya, Aamir Mushtaq","doi":"10.1080/20905998.2023.2295041","DOIUrl":"https://doi.org/10.1080/20905998.2023.2295041","url":null,"abstract":"","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"23 62","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139156110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-25DOI: 10.1080/20905998.2023.2298048
Eric Chung, W. Atmoko, R. Saleh, R. Shah, Ashok Agarwal
{"title":"Sixth edition of the World Health Organization laboratory manual of semen analysis: Updates and essential take away for busy clinicians","authors":"Eric Chung, W. Atmoko, R. Saleh, R. Shah, Ashok Agarwal","doi":"10.1080/20905998.2023.2298048","DOIUrl":"https://doi.org/10.1080/20905998.2023.2298048","url":null,"abstract":"","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"24 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139159696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-07DOI: 10.1080/20905998.2023.2291628
P. Kavoussi, P. Birowo, R. Saleh, R. Shah, Ashok Agarwal
{"title":"Varicocele and male infertility conundrum: Making sense of a never-ending story for the busy clinician","authors":"P. Kavoussi, P. Birowo, R. Saleh, R. Shah, Ashok Agarwal","doi":"10.1080/20905998.2023.2291628","DOIUrl":"https://doi.org/10.1080/20905998.2023.2291628","url":null,"abstract":"","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"59 38","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138592542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-30DOI: 10.1080/20905998.2023.2287869
Ahmed Reda, Adel A Kurkar, Mahmoud Mohamad Shalaby, Mohammed Abdelhafez, Mahmoud Osman, Sherif Abulsorour
{"title":"Combined on-demand sildenafil citrate and tramadol hydrochloride is an effective and safe treatment for premature ejaculation: A randomized placebo-controlled double-blind clinical trial","authors":"Ahmed Reda, Adel A Kurkar, Mahmoud Mohamad Shalaby, Mohammed Abdelhafez, Mahmoud Osman, Sherif Abulsorour","doi":"10.1080/20905998.2023.2287869","DOIUrl":"https://doi.org/10.1080/20905998.2023.2287869","url":null,"abstract":"","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"414 27","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139205191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives Sperm DNA fragmentation (SDF) is a molecular marker of sperm chromatin health. Elevated SDF is associated with male infertility, recurrent pregnancy loss, and failure of assisted reproductive technologies (ART). In 2021, the sixth edition of the World Health Organization (WHO) Manual for the Laboratory Examination and Processing of Human Semen has listed SDF as an extended test of semen that can be ordered under certain circumstances. However, the manual neither explained the indications for testing nor provided clear guidance on diagnostic thresholds.
{"title":"Sperm DNA fragmentation in male infertility: From bench to bedside","authors":"Ala’a Farkouh, Ramadan Saleh, Rupin Shah, Ashok Agarwal","doi":"10.1080/20905998.2023.2278200","DOIUrl":"https://doi.org/10.1080/20905998.2023.2278200","url":null,"abstract":"Objectives Sperm DNA fragmentation (SDF) is a molecular marker of sperm chromatin health. Elevated SDF is associated with male infertility, recurrent pregnancy loss, and failure of assisted reproductive technologies (ART). In 2021, the sixth edition of the World Health Organization (WHO) Manual for the Laboratory Examination and Processing of Human Semen has listed SDF as an extended test of semen that can be ordered under certain circumstances. However, the manual neither explained the indications for testing nor provided clear guidance on diagnostic thresholds.","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"26 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-06DOI: 10.1080/20905998.2023.2277081
Ahmed Mahmoud Hasan, Mohammed Sayed Abdelkader, Mostafa AbdelRazek Ahmed, Mahmoud Mohsen Mohammed, Gamal Abdelhamid Alsaghier
Objective To compare the efficacy of tadalafil alone, dapoxetine alone, and tadalafil with dapoxetine as a combination therapy for the treatment of premature ejaculation.
目的比较他达拉非单用、达泊西汀单用及他达拉非联用达泊西汀治疗早泄的疗效。
{"title":"Prospective comparison of tadalafil 5 mg, dapoxetine 30 mg, and the combination of both in the treatment of premature ejaculation","authors":"Ahmed Mahmoud Hasan, Mohammed Sayed Abdelkader, Mostafa AbdelRazek Ahmed, Mahmoud Mohsen Mohammed, Gamal Abdelhamid Alsaghier","doi":"10.1080/20905998.2023.2277081","DOIUrl":"https://doi.org/10.1080/20905998.2023.2277081","url":null,"abstract":"Objective To compare the efficacy of tadalafil alone, dapoxetine alone, and tadalafil with dapoxetine as a combination therapy for the treatment of premature ejaculation.","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135636445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-16DOI: 10.1080/20905998.2023.2254960
Zulfikar Ali, Reginald Rustandi, Mohammad Sulchan, Ponco Birowo, Tri Indah Winarni
This systematic review and meta-analysis aims to identify the main risk factors for nephrolithiasis in Asian populations, with comparisons to European and American populations. Using a comprehensive literature search across PubMed, Science Direct, and ResearchGate, in accordance with the Preferred Reporting Items of Systematic reviews and Meta-Analysis (PRISMA) guidelines, we synthesized data from 11 geographically diverse studies. Our findings reveal substantial population-specific differences in nephrolithiasis risk factors, particularly familial history, water consumption, and smoking patterns. In Asian populations, a 60% increase in risk was associated with a family history of nephrolithiasis. In the meantime, drinking sources also affected nephrolithiasis risk, with the consumption of boiled water being associated with a 25% increase in risk compared to consumption of bottled or mineral water. These findings highlight the importance of tailoring preventive strategies and treatments to specific risk factors, taking into account regional variations, and call for additional research to understand the complex interaction between genetic, environmental, and lifestyle factors in the development of nephrolithiasis.
{"title":"Comparing the risk factors of nephrolithiasis in Asian countries population: A systematic review and meta-analysis","authors":"Zulfikar Ali, Reginald Rustandi, Mohammad Sulchan, Ponco Birowo, Tri Indah Winarni","doi":"10.1080/20905998.2023.2254960","DOIUrl":"https://doi.org/10.1080/20905998.2023.2254960","url":null,"abstract":"This systematic review and meta-analysis aims to identify the main risk factors for nephrolithiasis in Asian populations, with comparisons to European and American populations. Using a comprehensive literature search across PubMed, Science Direct, and ResearchGate, in accordance with the Preferred Reporting Items of Systematic reviews and Meta-Analysis (PRISMA) guidelines, we synthesized data from 11 geographically diverse studies. Our findings reveal substantial population-specific differences in nephrolithiasis risk factors, particularly familial history, water consumption, and smoking patterns. In Asian populations, a 60% increase in risk was associated with a family history of nephrolithiasis. In the meantime, drinking sources also affected nephrolithiasis risk, with the consumption of boiled water being associated with a 25% increase in risk compared to consumption of bottled or mineral water. These findings highlight the importance of tailoring preventive strategies and treatments to specific risk factors, taking into account regional variations, and call for additional research to understand the complex interaction between genetic, environmental, and lifestyle factors in the development of nephrolithiasis.","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136112446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-16DOI: 10.1080/20905998.2023.2252227
Basheer N. Elmohamady, Mahmoud M. Farag, Hamouda W. Sherif, Ahmed EL Ghobashy, Mohamed A. AL Hefnawy
Background To evaluate the predictive ability of the RIRS scoring system and the RUSS in predicting stone-free rate (SFR) after retrograde intrarenal surgery (RIRS).
目的评价RIRS评分系统和RUSS对逆行肾内手术(RIRS)后无结石率(SFR)的预测能力。
{"title":"Predicting stone free rate after retrograde intrarenal surgery using RIRS scoring system versus Resorlu Unsal stone score (RUSS)","authors":"Basheer N. Elmohamady, Mahmoud M. Farag, Hamouda W. Sherif, Ahmed EL Ghobashy, Mohamed A. AL Hefnawy","doi":"10.1080/20905998.2023.2252227","DOIUrl":"https://doi.org/10.1080/20905998.2023.2252227","url":null,"abstract":"Background To evaluate the predictive ability of the RIRS scoring system and the RUSS in predicting stone-free rate (SFR) after retrograde intrarenal surgery (RIRS).","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136112300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-14DOI: 10.1080/2090598x.2023.2208492
Hassan F. Abol-Elnazer, Amira Awadalla, Asmaa E. Ahmed, Hassan Abol-Enein, Munir Ali Al Ganzouri, Amr A. Elsawy
Background Urothelial bladder carcinoma (UBC) is usually detected during work-up for hematuria. Cystoscopy and/or contrast-enhanced imaging are the gold standard tools for UBC diagnosis, despite limited by being invasive, expensive and low yield in small flat tumors.Objectives To assess the diagnostic performance of urine-based DNA methylation of six genes (GATA4, P16, P14, APC, CDH1 and CD99) for UBC detection in patients with hematuria.Patients and methods Voided urine was collected from consecutive patients presented with hematuria for urine cytology and DNA methylation assay of the assigned genes using methylation-specific Polymerase Chain Reaction (PCR). Further assessment by office cystoscopy and imaging with subsequent inpatient cystoscopic biopsy for positive findings was done. The diagnostic characteristics of DNA methylation and urine cytology were assessed based on its capability to predict UBC.Results We included 246 patients in the study with identified macroscopic hematuria in 204 (82.9%) patients. Positive cytology was found in 78 (31.7%) patients. DNA methylation of GATA4, P16, P14, APC, CDH1 and CD99 genes was identified in 127 (51.6%), 52 (21.1%), 117 (47.6%), 106 (43.1%), 90 (36.6%) and 71 (28.9%) patients, respectively. The sensitivity of the assigned genes for UBC detection ranges from 35% (95%CI: 31–39) to 83% (95%CI: 79–87). Optimal specificity (SP) (100%) was noted for P16, APC and CDH1 genes. While for the other genes (GATA4, P14 and CD99), the SP was 95% (95%CI: 92–98), 96% (95%CI: 92–99) and 97% (95%CI: 93–99), respectively. On multivariate logistic regression analysis, all genes exclusively demonstrated independent prediction of UBC. On receiver operator characteristic (ROC) analysis, all tested genes methylation showed superior area under the curve (AUC) when compared to urine cytology.Conclusions We have developed a novel urine-based DNA methylation assay for detection of UBC in patients with hematuria with superior diagnostic performance and independent predictive capacity over urine cytology.
{"title":"Novel urine-based DNA methylation biomarkers for urothelial bladder carcinoma detection in patients with hematuria","authors":"Hassan F. Abol-Elnazer, Amira Awadalla, Asmaa E. Ahmed, Hassan Abol-Enein, Munir Ali Al Ganzouri, Amr A. Elsawy","doi":"10.1080/2090598x.2023.2208492","DOIUrl":"https://doi.org/10.1080/2090598x.2023.2208492","url":null,"abstract":"Background Urothelial bladder carcinoma (UBC) is usually detected during work-up for hematuria. Cystoscopy and/or contrast-enhanced imaging are the gold standard tools for UBC diagnosis, despite limited by being invasive, expensive and low yield in small flat tumors.Objectives To assess the diagnostic performance of urine-based DNA methylation of six genes (GATA4, P16, P14, APC, CDH1 and CD99) for UBC detection in patients with hematuria.Patients and methods Voided urine was collected from consecutive patients presented with hematuria for urine cytology and DNA methylation assay of the assigned genes using methylation-specific Polymerase Chain Reaction (PCR). Further assessment by office cystoscopy and imaging with subsequent inpatient cystoscopic biopsy for positive findings was done. The diagnostic characteristics of DNA methylation and urine cytology were assessed based on its capability to predict UBC.Results We included 246 patients in the study with identified macroscopic hematuria in 204 (82.9%) patients. Positive cytology was found in 78 (31.7%) patients. DNA methylation of GATA4, P16, P14, APC, CDH1 and CD99 genes was identified in 127 (51.6%), 52 (21.1%), 117 (47.6%), 106 (43.1%), 90 (36.6%) and 71 (28.9%) patients, respectively. The sensitivity of the assigned genes for UBC detection ranges from 35% (95%CI: 31–39) to 83% (95%CI: 79–87). Optimal specificity (SP) (100%) was noted for P16, APC and CDH1 genes. While for the other genes (GATA4, P14 and CD99), the SP was 95% (95%CI: 92–98), 96% (95%CI: 92–99) and 97% (95%CI: 93–99), respectively. On multivariate logistic regression analysis, all genes exclusively demonstrated independent prediction of UBC. On receiver operator characteristic (ROC) analysis, all tested genes methylation showed superior area under the curve (AUC) when compared to urine cytology.Conclusions We have developed a novel urine-based DNA methylation assay for detection of UBC in patients with hematuria with superior diagnostic performance and independent predictive capacity over urine cytology.","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135189630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-26eCollection Date: 2023-01-01DOI: 10.1080/2090598X.2023.2203605
Clarissa Tania, Edwin Raja Pardamean Lumban Tobing, Christiano Tansol, Patricia Diana Prasetiyo, Caesar Khairul Wallad, Timotius Ivan Hariyanto
{"title":"Authors' response:Vitamin D supplementation for improving sperm parameters in infertile men: A systematic review and meta-analysis of randomized clinical trials.","authors":"Clarissa Tania, Edwin Raja Pardamean Lumban Tobing, Christiano Tansol, Patricia Diana Prasetiyo, Caesar Khairul Wallad, Timotius Ivan Hariyanto","doi":"10.1080/2090598X.2023.2203605","DOIUrl":"10.1080/2090598X.2023.2203605","url":null,"abstract":"","PeriodicalId":8113,"journal":{"name":"Arab Journal of Urology","volume":"1 1","pages":"214-215"},"PeriodicalIF":1.3,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10763586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41533860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}