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Subnuclear lipid-containing vacuolization in cases of ketoacidosis - correlation of morphological findings and ketone body concentrations. 酮症酸中毒病例的亚核含脂空泡化——形态学发现与酮体浓度的相关性。
Pub Date : 2016-08-01 DOI: 10.4323/rjlm.2020.363
Kirsten Wollner, C. Hess, B. Madea
In a study on alcoholics, diabetics, cases of hypothermia, combinations of alcoholism, diabetes and hypothermia as well as 55 controls, ketone body measurements were performed in femoral vein blood, heart blood, vitreous humor, cerebrospinal fluid and urine. Histological investigations were carried out on the kidneys of the deceased. In addition to HE-staining, the cuts were stained with Sudan and PAS to allow differentiation between lipids and glycogens. The degree of stainability in the Sudan stains was correlated with the ketone body concentrations measured. In those cases in which elevated ketone body concentrations were measured, marked fat deposits in the renal tubular epithelial cells could be demonstrated with the Sudan staining method. The higher the stainability the higher the ketone body concentrations. The ketone body concentrations measured in the various body fluids correlated with the intensity of fat stainability.
在一项针对酗酒者、糖尿病患者、体温过低患者、酒精中毒、糖尿病和体温过低合并病例以及55名对照者的研究中,对股静脉血液、心脏血液、玻璃体体液、脑脊液和尿液进行了酮体测量。对死者的肾脏进行了组织学检查。除了he染色外,还用苏丹红染色和PAS染色,以区分脂质和糖原。苏丹红染色的染色程度与测定的酮体浓度有关。在酮体浓度升高的病例中,可以用苏丹染色法证明肾小管上皮细胞中有明显的脂肪沉积。染色度越高,酮体浓度越高。在各种体液中测量的酮体浓度与脂肪染色的强度相关。
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引用次数: 1
[Skull fracture or accessory suture in a child?]. [儿童颅骨骨折或附属缝合?]。
Pub Date : 2016-05-01
Katrin Burkhard, Lena M Lange, Stefanie Plenzig, Marcel A Verhoff, Sarah C Kölzer

Differentiation between accessory sutures and fractures in the skull of an infant can be difficult. Apart from the regular sutures there is a multitude of variations that may be mistaken for a fracture line. Such variations include for instance the intraparietal suture between the two ossification centers of the parietal bone or the mendosal suture between the supraoccipital and interparietal bone of the occipital squama. The presented case refers to an approximately 20-month-old female child. During autopsy, a discontinuity in the right paramedian posterior cranial fossa parallel to the internal occipital crest with connection to the foramen magnum was observed. The macroscopic findings suggested a fracture line because of its course. However, neither a hemorrhage in the soft tissue nor callus formation was discernible. The discontinuity was preserved with the adjacent parts of the occipital bone for further histological examination. In the report of a cranial CT, which was carried out five days before the child's death, an accessory suture paramedially in the right posterior cranial fossa was described. When the clinical CT records were re-evaluated, a similar discontinuity at the corresponding position on the other side was detected, though of noticeably shorter length. Additionally, the preserved occipital bone fragment including the discontinuity was histologically processed. In the radiological literature, precise (radiological) criteria for differential diagnosis are indicated. A zigzag pattern with sclerotic borders and a bilateral and fairly symmetric occurrence indicate a suture, whereas a sharp lucency with non-sclerotic edges and a unilateral occurrence indicate a fracture. Taking all the findings into account, the depicted discontinuity was regarded as an accessory suture. This case demonstrates that differentiation between a fracture and an accessory suture may be difficult in the autopsy of a child and underlines the importance of a postmortem CT examination.

区分婴儿颅骨的附属缝合线和骨折是很困难的。除了常规的缝合线外,还有许多不同的缝合线可能被误认为是骨折线。这种变异包括例如顶骨两个骨化中心之间的顶骨内缝线或枕鳞的枕上骨和顶骨间缝线。本病例涉及一名大约20个月大的女婴。尸检时,在与枕骨大孔相连的右侧后颅窝旁正中平行处观察到一个不连续性。由于其过程,宏观表现为骨折线。然而,既没有软组织出血,也没有骨痂形成。保留与枕骨相邻部分的不连续性,以便进一步进行组织学检查。在儿童死亡前5天进行的头颅CT报告中,描述了右侧后颅窝的辅助缝合。当重新评估临床CT记录时,在另一侧相应位置检测到类似的不连续,尽管长度明显较短。此外,保存的枕骨碎片包括不连续性进行组织学处理。在放射学文献中,明确了鉴别诊断的放射学标准。具有硬化边缘的锯齿形图案和两侧相当对称的出现表明缝合线,而具有非硬化边缘的锐利透光和单侧出现表明骨折。考虑到所有的发现,所描述的不连续性被认为是副缝合线。本病例表明,在儿童尸检中区分骨折和附属缝合线可能很困难,并强调了尸检CT检查的重要性。
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引用次数: 0
[Reconstructive investigations and identification measures in unknown soldiers of the Second World War]. [第二次世界大战身份不明士兵的重建调查与鉴定措施]。
Pub Date : 2016-05-01
Eilin Jopp-van Well, Axel Gehl, Dennis Säring, Michael Amling, Michael Hahn, Jan Sperhake, Christa Augustin, Oliver Krebs, Klaus Püschel

The article reports on the exhumation and identification of unknown soldiers from the Second World War. With the help of medicolegal investigation and reconstruction methods an American pilot presumably murdered by a shot to the head (lynch law) and an interned Italian soldier could be identified after about 70 years and brought back home.

这篇文章报道了第二次世界大战中无名士兵的挖掘和身份鉴定。在医学调查和重建方法的帮助下,一名可能被枪杀(私刑法)的美国飞行员和一名被拘留的意大利士兵的身份在时隔70年后得以确认,并被带回家。
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引用次数: 0
[Sepsis due to fusobacteria in a young adult]. [年轻成人中梭杆菌引起的败血症]。
Pub Date : 2016-05-01
Gerhard Kernbach-Wighton, Rainer Amberg, Marijo Parchina, Cornelius Hess, Burkhard Madea

Fusobacteria belong to the normal population of the pharyngeal mucosa as well as the mucosa of the upper airways and the gastrointestinal tract. Infections are comparatively rare. The most common causative organism is Fusobacterium necrophorum. A well-known infection caused by this germ is Lemierre's syndrome. In the presented case, a 19-year-old man (123 kg body weight, 186 cm body length) was found dead in his bed in the morning after having complained of muscular fatigue and vomiting the previous day. Autopsy was carried out only two days after death. At that time, the body showed marked putrefaction with partial greenish discoloration and marbling of the skin although it had been stored in a refrigerator at +2 degrees C in the meantime. While the autopsy itself revealed no cause of death, microbiological examination of a smear from the left lower pulmonary lobe demonstrated Staphylococcus aureus and Fusobacterium necrophorum. Toxicological investigations produced negative results throughout. The cause of death was defined as sepsis caused by Fusobacterium necrophorum.

梭杆菌属咽部粘膜、上呼吸道和胃肠道粘膜的正常菌群。感染相对较少。最常见的致病生物是坏死梭杆菌。由这种细菌引起的一种众所周知的感染是莱米尔综合征。在本例中,一名19岁男子(体重123公斤,体长186厘米)在前一天主诉肌肉疲劳和呕吐后,于早上被发现死在床上。尸体解剖是在死后两天进行的。当时,尸体在+2摄氏度的冰箱中保存了一段时间,但却显示出明显的腐烂,部分变色,皮肤上有大理石纹。虽然尸检本身没有显示死因,但左下肺叶的微生物涂片检查显示金黄色葡萄球菌和坏死梭杆菌。毒理学调查结果均为阴性。死亡原因确定为坏死梭杆菌引起的败血症。
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引用次数: 0
[True color accuracy in digital forensic photography]. [数字法医摄影的真彩色准确性]。
Pub Date : 2016-05-01
Frank Ramsthaler, Christoph G Birngruber, Ann-Katrin Kröll, Mattias Kettner, Marcel A Verhoff

Forensic photographs not only need to be unaltered and authentic and capture context-relevant images, along with certain minimum requirements for image sharpness and information density, but color accuracy also plays an important role, for instance, in the assessment of injuries or taphonomic stages, or in the identification and evaluation of traces from photos. The perception of color not only varies subjectively from person to person, but as a discrete property of an image, color in digital photos is also to a considerable extent influenced by technical factors such as lighting, acquisition settings, camera, and output medium (print, monitor). For these reasons, consistent color accuracy has so far been limited in digital photography. Because images usually contain a wealth of color information, especially for complex or composite colors or shades of color, and the wavelength-dependent sensitivity to factors such as light and shadow may vary between cameras, the usefulness of issuing general recommendations for camera capture settings is limited. Our results indicate that true image colors can best and most realistically be captured with the SpyderCheckr technical calibration tool for digital cameras tested in this study. Apart from aspects such as the simplicity and quickness of the calibration procedure, a further advantage of the tool is that the results are independent of the camera used and can also be used for the color management of output devices such as monitors and printers. The SpyderCheckr color-code patches allow true colors to be captured more realistically than with a manual white balance tool or an automatic flash. We therefore recommend that the use of a color management tool should be considered for the acquisition of all images that demand high true color accuracy (in particular in the setting of injury documentation).

法医照片不仅需要保持原貌和真实性,并捕捉与背景相关的图像,同时对图像清晰度和信息密度有一定的最低要求,而且色彩准确性也起着重要作用,例如,在评估伤害或掩埋阶段,或在识别和评估照片中的痕迹。对色彩的感知不仅因人而异,而且作为图像的离散属性,数码照片中的色彩也在相当程度上受到照明、采集设置、相机和输出介质(打印、显示器)等技术因素的影响。由于这些原因,到目前为止,一致的色彩精度在数码摄影中一直受到限制。因为图像通常包含丰富的颜色信息,特别是复杂或复合颜色或颜色的阴影,以及波长依赖的灵敏度因素,如光和阴影可能会因相机而异,发布相机捕获设置的一般建议的有用性是有限的。我们的研究结果表明,使用SpyderCheckr技术校准工具,本研究中测试的数码相机可以最好、最真实地捕获真实的图像颜色。除了校准过程的简单和快速等方面外,该工具的另一个优点是结果独立于所使用的相机,也可用于显示器和打印机等输出设备的色彩管理。与手动白平衡工具或自动闪光灯相比,SpyderCheckr颜色代码补丁允许更真实地捕捉真实的颜色。因此,我们建议应考虑使用色彩管理工具来获取所有需要高真彩色精度的图像(特别是在伤害文件的设置中)。
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引用次数: 0
[An unusual bodily injury]. [不寻常的身体伤害]。
Pub Date : 2016-05-01
Gerhard Kernbach-Wighton, Cornelius Hess, Burkhard Madea

In most cases, bodily harm results from the use of sharp objects or blunt force. This paper deals with a 42-year-old pharmacist who was known to the police and the courts because of several previous convictions for bodily injury. The man had visited a pub just before it closed and was therefore not served any drinks. He got angry about this and returned to his pharmacy (within walking distance) to fetch three disposable syringes which he filled with phosphoric acid (85%). Through the open pub window, he splattered the acid from the syringes on two guests and the host, who were hit on the upper part of their bodies and the arms. All the victims developed dermal alterations such as focal erythema and small blisters (pemphigus-like efflorescences, as already described by Weyrich). At first, the pharmacist denied the use of phosphoric acid and claimed to have used a mixture of urine and water. Examinations of spots on the still unwashed clothes revealed very low pH-values (ca. 2.0; pH-Indicator-Stripes, Merck; Medi-Test, Machery & Nagel). Tests for substances typical of urine produced completely negative results. However, very high phosphate concentrations were found on the spots in question. Thus, the probability that the pharmacist had used phosphoric acid to commit the offence was very high. The pharmacist was sentenced to one year and two months' imprisonment for dangerous bodily harm according to Section 224 German Criminal Code. In accordance with the law, phosphoric acid was classified as "poison", for which application on the skin is sufficient.

在大多数情况下,身体伤害是由使用尖锐物体或钝器造成的。本文涉及一名42岁的药剂师,他因多次身体伤害罪被警方和法院所知。这名男子在一家酒吧关门前去了,因此没有提供任何饮料。他对此很生气,回到药房(步行即可到达)拿了三个一次性注射器,里面装满了磷酸(85%)。透过开着的酒吧窗户,他将注射器里的酸泼向两名客人和主人,他们的上半身和手臂被击中。所有的受害者都出现了皮肤变化,如局灶性红斑和小水泡(天疱疮样的红肿,Weyrich已经描述过)。起初,药剂师否认使用了磷酸,并声称使用了尿液和水的混合物。对未洗衣服上的斑点的检查显示ph值非常低(约2.0;pH-Indicator-Stripes,默克公司;介质测试,机械和Nagel)。对尿液中典型物质的检测结果完全为阴性。然而,在这些斑点上发现了非常高的磷酸盐浓度。因此,药剂师使用磷酸进行犯罪的可能性非常高。根据德国刑法第224条,这名药剂师因危险的身体伤害被判处一年零两个月的监禁。根据法律,磷酸被归类为“毒药”,在皮肤上使用就足够了。
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引用次数: 0
[Stature estimation from sagittal and coronal suture lengths for Central European individuals]. [根据中欧个体矢状面和冠状面缝线长度估算身高]。
Pub Date : 2016-05-01
Tesseera V Kolencherry, Christoph G Birngruber, Frank Ramsthaler, Marcel A Verhoff, Sarah C Kölzer

$Human skulls frequently represent the only skeletal remains of an unidentified corpse available for forensic osteological examination. Skulls are very useful in reliably determining sex and also yield fairly good clues to an individual's age and ancestry. To date, however, a sufficiently accurate correlation between skull measurements and stature could not be found. In contrast, the results of a study by Rao et al. (2009) seemed to be promising, by finding a good correlation between the length of the coronal and sagittal sutures and stature in a male Indian population. In an attempt to verify the transferability of their results to a Central European population, the authors measured the length of the sagittal and coronal sutures with a tape measure along with body height in the course of 117 autopsies performed at the Institute of Forensic Medicine at the University of Giessen during 2009 and 2010. The age of the individuals measured ranged from 15 to 96 years (mean value 52.8, median 51 years). Of these individuals, 82 were male and 35 were female. The length of the sagittal suture with respect to body length yielded a correlation coefficient of only r = 0.045 (p = 0.617) in the regression analysis. Similar results were found for the coronal suture: In this case the correlation coefficient was r = 0.015. With an assumed maximum permissible probability of error of α = 0.05, none of the performed regression analyses were found to be statistically significant. As expected, our results suggest that neither the length of the sagittal nor the length of the coronal suture is suitable for a forensic estimation of stature for Central European individuals.

$人的头盖骨往往是可用于法医骨学检查的身份不明的尸体的唯一骨骼残骸。头骨在可靠地确定性别方面非常有用,也提供了关于个人年龄和祖先的相当好的线索。然而,到目前为止,还没有发现头骨尺寸和身高之间足够精确的相关性。相比之下,Rao等人(2009)的研究结果似乎很有希望,他们在印度男性人群中发现冠状和矢状缝合线的长度与身高之间存在良好的相关性。为了验证其结果在中欧人群中的可转移性,作者在2009年至2010年期间在吉森大学法医研究所进行的117例尸检中,用皮尺测量了矢状和冠状缝合线的长度以及身体高度。被测个体的年龄从15岁到96岁不等(平均值52.8岁,中位数51岁)。其中82只为雄性,35只为雌性。矢状缝线长度与体长的相关系数在回归分析中仅为r = 0.045 (p = 0.617)。冠状缝合线的相关系数为r = 0.015。假设最大允许误差概率为α = 0.05,所有进行的回归分析均无统计学显著性。正如预期的那样,我们的结果表明,无论是矢状线的长度还是冠状线的长度都不适合中欧个体的身高法医估计。
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引用次数: 0
[Fatal explosion injuries from blasting a cigarette machine]. [卷烟机爆炸造成的致命爆炸伤害]。
Pub Date : 2016-03-01
Burkhard Madea, Hani Ridwan, Volker Längin, Elke Doberentz

In the last few years, a growing number of cases have been reported in Germany in which vending machines have been blasted by criminals to get at the money. Thus, it was only a question of time for the first fatalities to occur as a consequence of such careless explosions. We report on the death of a 16-year-old boy who died after triggering an explosion by spraying a deodorant into the coin slot of a cigarette machine. Death was caused by severe craniocerebral trauma due to tertiary blast-related injuries when the front plate of the machine hit the victim's cerebral and facial skull.

在过去的几年里,德国报道了越来越多的自动售货机被犯罪分子炸毁以骗取钱财的案件。因此,由于这种粗心的爆炸而造成的第一次死亡只是时间问题。我们报道一名16岁男孩的死亡,他将除臭剂喷洒到香烟贩卖机的投币口引发爆炸后死亡。死亡是由于第三次爆炸造成的严重颅脑损伤造成的,当时机器的前板击中了受害者的大脑和面部头骨。
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引用次数: 0
[A critical review of applied criminology]. [应用犯罪学评论]。
Pub Date : 2016-03-01
Alexander Vollbach

By reporting on a recent decision of the Regional Court (LG) of Marburg (Germany) calling attention to applied criminology, a concept still insufficiently considered in the administration of criminal justice, the paper argues that professional action in the execution of the sentence represents nothing else but applied criminology. Based on this assumption, the paper discusses practical diagnosis and correctional planning. Beyond that, the paper deals with the future of criminology. In the opinion of the author an important aspect for the future of criminology will be if it will be able to remain in touch with the world in which we live, as an independent empirical science. Applied criminology and its methodology constitute the link between science and practice.

通过报道马尔堡(德国)地区法院(LG)最近的一项决定,呼吁关注应用犯罪学,这一概念在刑事司法行政中仍未得到充分考虑,本文认为,在执行判决时的专业行动只代表应用犯罪学。基于这一假设,本文讨论了实际诊断和纠正方案。除此之外,这篇论文还探讨了犯罪学的未来。在作者看来,犯罪学未来的一个重要方面将是,它是否能够作为一门独立的经验科学,与我们生活的世界保持联系。应用犯罪学及其方法论构成了科学与实践之间的联系。
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引用次数: 0
High variation of congener alcohols in apple wines. 苹果酒中同族醇含量变化大。
Pub Date : 2016-03-01
Clara S E Klinger, Katharina A Derra, Gerald Reiter, Cora Wunder, Stefan W Toennes, Alexander Paulke

Congener alcohol (CA) analysis became an important tool in forensic science to prove the kind of alcoholic beverage consumed. The aim of the present study was to determine the influence of yeast strain and apple variety on the formation of congener alcohols in self-produced apple wine. There exist data on CA patterns of industrially produced alcoholic beverages, but these are not available for apple wine. Must from five different commercial as well as from six genuine apple varieties were used for fermentation under similar conditions CA formation was monitored during the fermentation process. Additionally, nine commercial apple wines from commercial producers were analyzed. Analysis was performed by headspaces-GC-MS. All apple wines contained markedly high contents of the CA 3-methylbutan-1-ol (88-251 mg/L). Compared to self-produced apple wines from genuine musts the industrial apple wines (purchased in supermarkets and self-produced from commercial musts) exhibited significant differences in methanol concentrations(8.5-94 mg/L), whereas all other CAs, such as propan-1-ol, butan-1-0l, 2-methylpropan-1-ol(isobutanol), 3-methyl-butan-1-oi, and 2-methylbutan-1-oi, were found to be present in similar concentrations. Methanol was not detectable in apple wine made from genuine musts during fermentation but after a storage period. In some cases, concentrations of some CAs additionally changed during storage. This may be explained by a secondary (unwanted) fermentation after bottling. According to the data obtained in the present study, it is recommended to analyze a sample of the allegedly consumed apple wine in forensic cases, rather than to rely on data obtained from the literature or from some data collections.

同族酒精(CA)分析已成为法医学证明酒精饮料种类的重要工具。本研究的目的是确定酵母菌株和苹果品种对自产苹果酒中同类醇形成的影响。有关于工业生产的酒精饮料的CA模式的数据,但这些数据不能用于苹果酒。在相似的条件下,用5个不同的商品苹果和6个真正的苹果品种的果脯进行发酵,监测发酵过程中CA的形成。此外,还分析了来自商业生产商的9种商业苹果酒。采用顶空-气相色谱-质谱分析。所有苹果酒的CA 3-甲基丁醇含量均显著高(88-251 mg/L)。工业苹果酒(从超市购买)和商业苹果酒(从商业苹果酒中自行生产)相比,甲醇浓度(8.5-94 mg/L)存在显著差异,而所有其他CAs,如丙烯-1-醇、丁烷-1- 01、2-甲基丙烯-1-醇(异丁醇)、3-甲基丁烷-1-油和2-甲基丁烷-1-油,被发现存在相似的浓度。在发酵过程中,但在储存一段时间后,用真正的葡萄酿制的苹果酒中检测不到甲醇。在某些情况下,某些CAs的浓度在储存过程中还会发生变化。这可以解释为装瓶后的二次(不必要的)发酵。根据本研究获得的数据,建议在法医案件中分析据称消耗的苹果酒的样本,而不是依靠从文献或一些数据收集中获得的数据。
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引用次数: 0
期刊
Archiv fur Kriminologie
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