首页 > 最新文献

Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress最新文献

英文 中文
[Attractive work schedules--the Sinsheim model]. (吸引人的工作时间表——Sinsheim模式)。
B Kuhnert-Frey

The head of the anaesthetic department in a teaching district general hospital affiliated to the University Heidelberg, gives an appraisal of her 20 year experience in dealing with organising part-time employment for doctors in her department. The project proved so successful that most doctors in the department changed from full-time to part-time employment. On average two thirds of the doctors choosing part-time employment are female, one third male. The advantages exceeded by far the disadvantages. The greater number of colleagues aids problem-solving. The disadvantages were overcome by organisational means and also by the active participation of the highly motivated colleagues. This project proved it is possible to make hospital work more attractive.

海德堡大学附属教学区综合医院麻醉科的负责人,对她20年来组织部门医生兼职工作的经验进行了评价。这个项目非常成功,以至于该部门的大多数医生都从全职转为兼职。选择兼职的医生中,平均三分之二是女性,三分之一是男性。优点远远超过缺点。更多的同事有助于解决问题。这些缺点通过组织手段和高度积极的同事的积极参与被克服了。这个项目证明了使医院工作更有吸引力是可能的。
{"title":"[Attractive work schedules--the Sinsheim model].","authors":"B Kuhnert-Frey","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The head of the anaesthetic department in a teaching district general hospital affiliated to the University Heidelberg, gives an appraisal of her 20 year experience in dealing with organising part-time employment for doctors in her department. The project proved so successful that most doctors in the department changed from full-time to part-time employment. On average two thirds of the doctors choosing part-time employment are female, one third male. The advantages exceeded by far the disadvantages. The greater number of colleagues aids problem-solving. The disadvantages were overcome by organisational means and also by the active participation of the highly motivated colleagues. This project proved it is possible to make hospital work more attractive.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"929-36"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22350137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Quality and economy--contradictory demands]. 【质量与经济——矛盾的需求】。
H J Oestern, T Schwermann

Polytrauma treatment (40-60,000,-[symbol: see text]) and trauma killed victims (750,000,-[symbol: see text]) are a severe economical problem. The data of the German Trauma Registry show a significant influence of arrival time of the emergency doctor and lethality. There is also a significant increase of the length of stay at the intensive unit in severe thoracic and abdominal trauma (AIS > 3). The analysis of the audit filter for quality management showed between 1999-2000 a decrease of the time till first CCT from 41 to 31 minutes and for the first thoracic X-ray from 20 to 16 minutes. The German Trauma Registry includes till now more than 10,000 polytraumatized patients. There is an increase of 110% between the years 1998 and 2000.

多重创伤治疗(40-60,000,-[符号:见文本])和创伤致死受害者(75万,-[符号:见文本])是一个严重的经济问题。德国创伤登记处的数据显示急诊医生到达时间和死亡率有显著影响。严重胸腹外伤患者在重症监护病房的住院时间也显著增加(AIS > 3)。质量管理审计过滤器的分析显示,1999-2000年间,第一次CCT的时间从41分钟减少到31分钟,第一次胸部x线检查的时间从20分钟减少到16分钟。到目前为止,德国创伤登记处包括一万多名多重创伤患者。从1998年到2000年,增长了110%。
{"title":"[Quality and economy--contradictory demands].","authors":"H J Oestern,&nbsp;T Schwermann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Polytrauma treatment (40-60,000,-[symbol: see text]) and trauma killed victims (750,000,-[symbol: see text]) are a severe economical problem. The data of the German Trauma Registry show a significant influence of arrival time of the emergency doctor and lethality. There is also a significant increase of the length of stay at the intensive unit in severe thoracic and abdominal trauma (AIS > 3). The analysis of the audit filter for quality management showed between 1999-2000 a decrease of the time till first CCT from 41 to 31 minutes and for the first thoracic X-ray from 20 to 16 minutes. The German Trauma Registry includes till now more than 10,000 polytraumatized patients. There is an increase of 110% between the years 1998 and 2000.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"937-40"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22350138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Colonic carcinoma--state of the art. Primary and secondary prevention]. 结肠癌——最先进的技术。一级和二级预防]。
D Hartmann, J F Riemann

Considering the high incidence and mortality rate of colorectal cancer, great efforts are made for primary and secondary prevention. By doing so, primary prophylaxis includes the use of protective measures in order to prevent the development of adenomas and carcinomas. Epidemological studies have shown that nutrition or medication (e.g. NSAID) have an immediate influence on the pathogenesis of colorectal carcinomas. Secondary prevention includes early diagnosis and treatment of precursors of carcinomas. Considering this, colonoscopy is the cheapest and gentlest method and therefore the screening method of choice.

考虑到结直肠癌的高发病率和死亡率,人们在一级和二级预防方面做了很大的努力。通过这样做,初级预防包括使用保护措施,以防止腺瘤和癌的发展。流行病学研究表明,营养或药物(如非甾体抗炎药)对结直肠癌的发病有直接影响。二级预防包括早期诊断和治疗癌症的前体。考虑到这一点,结肠镜检查是最便宜和最温和的方法,因此是首选的筛查方法。
{"title":"[Colonic carcinoma--state of the art. Primary and secondary prevention].","authors":"D Hartmann,&nbsp;J F Riemann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Considering the high incidence and mortality rate of colorectal cancer, great efforts are made for primary and secondary prevention. By doing so, primary prophylaxis includes the use of protective measures in order to prevent the development of adenomas and carcinomas. Epidemological studies have shown that nutrition or medication (e.g. NSAID) have an immediate influence on the pathogenesis of colorectal carcinomas. Secondary prevention includes early diagnosis and treatment of precursors of carcinomas. Considering this, colonoscopy is the cheapest and gentlest method and therefore the screening method of choice.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"146-8"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22348787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laparoscopic fundoplication--what is proven?]. [腹腔镜下眼底复制术——证明了什么?]
H J Stein

Laparoscopic fundoplication has become a popular procedure but several questions remain unresolved. Although randomised trials suggest that antireflux surgery is a good alternative to continuous medical therapy, the selection of patients for surgery remains crucial to achieve success. There is currently no proof that antireflux surgery will reduce the risk for developing esophageal adenocarcinoma. Complications, side effects and failures appear to be higher after a laparoscopic approach as compared to conventional open surgery, particularly in un-experienced hands. Partial fundoplications and tailored approaches have so far not shown convincingly better results than those that can be achieved by short and floppy 360 fundoplication.

腹腔镜下翻底术已成为一种流行的手术,但仍有几个问题尚未解决。尽管随机试验表明,抗反流手术是持续药物治疗的一个很好的替代方案,但手术患者的选择仍然是取得成功的关键。目前还没有证据表明抗反流手术会降低患食管腺癌的风险。与传统的开放手术相比,腹腔镜手术的并发症、副作用和失败似乎更高,特别是在没有经验的患者中。到目前为止,局部复底和量身定制的方法并没有显示出令人信服的效果,而短而软的360度复底可以取得更好的效果。
{"title":"[Laparoscopic fundoplication--what is proven?].","authors":"H J Stein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Laparoscopic fundoplication has become a popular procedure but several questions remain unresolved. Although randomised trials suggest that antireflux surgery is a good alternative to continuous medical therapy, the selection of patients for surgery remains crucial to achieve success. There is currently no proof that antireflux surgery will reduce the risk for developing esophageal adenocarcinoma. Complications, side effects and failures appear to be higher after a laparoscopic approach as compared to conventional open surgery, particularly in un-experienced hands. Partial fundoplications and tailored approaches have so far not shown convincingly better results than those that can be achieved by short and floppy 360 fundoplication.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"184-7"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22348791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Necrosis of the semilunar bone--what is possible in ambulatory operations?]. [半月骨坏死——在门诊手术中可能发生什么?]。
W Förster, A Kerres

The author has been operating on cases of lunatum necrose using all usual operating methods, excluding attached vessel pisiforme transfer, increasingly over the past 9 years without an overnight stay in hospital being necessary for patients. Depending on the quality of the structure, we have not experienced any disadvantages in comparison to hospitalised patients. Regarding funding: The costs of these operations are covered and are justifiable in combination with additional hand operations within the outpatients department.

在过去的9年里,作者一直在使用所有常规手术方法对月牙坏死病例进行手术,不包括附着的扁平状血管转移,越来越多的患者无需住院过夜。根据结构的质量,与住院患者相比,我们没有遇到任何缺点。关于资金:这些手术的费用包括在内,并且与门诊部门的额外手工手术相结合是合理的。
{"title":"[Necrosis of the semilunar bone--what is possible in ambulatory operations?].","authors":"W Förster,&nbsp;A Kerres","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author has been operating on cases of lunatum necrose using all usual operating methods, excluding attached vessel pisiforme transfer, increasingly over the past 9 years without an overnight stay in hospital being necessary for patients. Depending on the quality of the structure, we have not experienced any disadvantages in comparison to hospitalised patients. Regarding funding: The costs of these operations are covered and are justifiable in combination with additional hand operations within the outpatients department.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"536-9"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22349765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Stabilizing intramedullary pediatric shaft fractures]. 稳定小儿髓内骨干骨折。
A Prokop, A Jubel, U Hahn, K E Rehm

Intramedullary stabilisation (Prévot-nailing) of shaft fractures in childhood allows full weight bearing without cast. Early fracture healing is seen by respecting soft tissue around fracture and by using distal or proximal approaches. Good indications of femoral shaft osteosynthesis are recommended in oblique and transverse fractures. Intramedullary stabilization seems to be a good alternative method instead of casting calf-shaft fractures. An unstable fracture of forearm may be treated intramedullary to avoid often observed displacement ad axim and rotation. Humoral fractures primary have to be treated conservatively. Only in displaced fractures or in cases with additional injuries an intramedullary procedure with free range of motion is recommended.

儿童期椎体骨折髓内固定(pracimvo -钉钉)允许完全负重,无需石膏。早期骨折愈合应尊重骨折周围的软组织,并采用远端或近端入路。在斜向骨折和横向骨折中,推荐采用股骨干骨固定术。髓内固定似乎是一个很好的替代方法,而不是铸造小腿轴骨折。前臂不稳定骨折可以髓内治疗,以避免经常观察到的移位、轴向和旋转。原发性体液骨折必须保守治疗。只有在移位性骨折或有额外损伤的情况下,才推荐髓内手术,使其活动范围自由。
{"title":"[Stabilizing intramedullary pediatric shaft fractures].","authors":"A Prokop,&nbsp;A Jubel,&nbsp;U Hahn,&nbsp;K E Rehm","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intramedullary stabilisation (Prévot-nailing) of shaft fractures in childhood allows full weight bearing without cast. Early fracture healing is seen by respecting soft tissue around fracture and by using distal or proximal approaches. Good indications of femoral shaft osteosynthesis are recommended in oblique and transverse fractures. Intramedullary stabilization seems to be a good alternative method instead of casting calf-shaft fractures. An unstable fracture of forearm may be treated intramedullary to avoid often observed displacement ad axim and rotation. Humoral fractures primary have to be treated conservatively. Only in displaced fractures or in cases with additional injuries an intramedullary procedure with free range of motion is recommended.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"689-94"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22350334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laparoscopic cholecystectomy--surgical standard in cholelithiasis]. [腹腔镜胆囊切除术-胆石症的手术标准]。
E Kraas, S Farke

Laparoscopic surgery showed a dramatic development in the last years of the 20th century. From the beginning laparoscopic cholecystectomy (LCCE) has been the pacemaker of this development. Today laparoscopic cholecystectomy is the first choice for treatment of cholecystolithiasis in nearly all surgical clinics. Therefore laparoscopic cholecystectomy is the most common part of minimal invasive technique. LCCE is the golden standard in therapy of gallstones, more than 90% of cholecystectomies in specialized clinics are done laparoscopically. It is an established, evidence based operation today. Open cholecystectomy is left for special indications only. A problem of LCCE is the occult carcinoma of the gallbladder. In histological proven carcinoma of the gallbladder LCCE is the adequate operation only for Tis and T1 carcinoma. In T2 and T3 carcinoma a radical oncologic resection with lymph node dissection should be performed. Due to the poor prognosis T4 tumors should be left with laparoscopic biopsy only.

腹腔镜手术在20世纪的最后几年有了巨大的发展。从一开始,腹腔镜胆囊切除术(LCCE)一直是这一发展的起搏器。如今,腹腔镜胆囊切除术几乎是所有外科诊所治疗胆囊结石的首选方法。因此腹腔镜胆囊切除术是微创技术中最常见的部分。LCCE是治疗胆结石的黄金标准,专科诊所90%以上的胆囊切除术都是腹腔镜下进行的。这是一项已确立的、以证据为基础的行动。开放胆囊切除术仅用于特殊适应症。LCCE的一个问题是胆囊的隐匿性癌。在组织学证实的胆囊癌中,LCCE仅适用于ti和T1癌。T2和T3癌应行根治性肿瘤切除术并淋巴结清扫。由于预后较差,T4肿瘤应仅行腹腔镜活检。
{"title":"[Laparoscopic cholecystectomy--surgical standard in cholelithiasis].","authors":"E Kraas,&nbsp;S Farke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Laparoscopic surgery showed a dramatic development in the last years of the 20th century. From the beginning laparoscopic cholecystectomy (LCCE) has been the pacemaker of this development. Today laparoscopic cholecystectomy is the first choice for treatment of cholecystolithiasis in nearly all surgical clinics. Therefore laparoscopic cholecystectomy is the most common part of minimal invasive technique. LCCE is the golden standard in therapy of gallstones, more than 90% of cholecystectomies in specialized clinics are done laparoscopically. It is an established, evidence based operation today. Open cholecystectomy is left for special indications only. A problem of LCCE is the occult carcinoma of the gallbladder. In histological proven carcinoma of the gallbladder LCCE is the adequate operation only for Tis and T1 carcinoma. In T2 and T3 carcinoma a radical oncologic resection with lymph node dissection should be performed. Due to the poor prognosis T4 tumors should be left with laparoscopic biopsy only.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"322-7"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22348762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Resection of tumor stenoses and stent implantations in advanced neoplasms of the esophagus, stomach and duodenum]. [食管、胃、十二指肠晚期肿瘤狭窄切除及支架植入术]。
D Tübergen, L Biermann, N Senninger

Up to now many people demand treatment only with symptoms of a progressed cancer disease. As curative therapy is often not possible any more, endoscopy offers valuable palliative treatment options. Tumor destructive methods are mainly used for soft exophytic neoplastic tissue, whereas stent implantation is the therapy of choice in all other cases, especially if severe obstruction is present. The advantage of this method is the immediate and long lasting effect. Because of the different stent types and indications there is no optimal universal stent, so that we have to choose the individual best endoprosthesis.

到目前为止,许多人只在出现癌症进展的症状时才要求治疗。由于治愈性治疗通常不再可能,内窥镜检查提供了有价值的姑息治疗选择。肿瘤破坏方法主要用于软外生性肿瘤组织,而支架植入术是所有其他情况下的治疗选择,特别是如果存在严重的梗阻。这种方法的优点是立竿见影,效果持久。由于支架类型和适应症不同,没有最优的通用支架,因此我们必须选择个体最佳的内假体。
{"title":"[Resection of tumor stenoses and stent implantations in advanced neoplasms of the esophagus, stomach and duodenum].","authors":"D Tübergen,&nbsp;L Biermann,&nbsp;N Senninger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Up to now many people demand treatment only with symptoms of a progressed cancer disease. As curative therapy is often not possible any more, endoscopy offers valuable palliative treatment options. Tumor destructive methods are mainly used for soft exophytic neoplastic tissue, whereas stent implantation is the therapy of choice in all other cases, especially if severe obstruction is present. The advantage of this method is the immediate and long lasting effect. Because of the different stent types and indications there is no optimal universal stent, so that we have to choose the individual best endoprosthesis.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"328-32"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22348763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[What can thoracic surgery accomplish in recurrent/second carcinoma of non-small-cell bronchial carcinoma?]. 【对于非小细胞支气管癌的复发/二次癌,胸外科手术能完成什么?】
P Wex, E Utta, V Haas

From 1990 to 2000, 2268 (29.9%) of 9600 lung cancer patients underwent resection for stage I to IIIA non-small cell lung cancer. Reinterventions were done in one hundred (3.5%) patients, for locoregional recurrence in 27, metachronous cancer in 42, metastasis or a third tumor in 31. A third intervention was performed in 23 patients and a fourth in two. The in-hospital mortality rate was 9%. The overall survival was 31.9% at five and 17.9% at ten years. The 5-year survival after the first intervention (reintervention) was 26% (11%) for local recurrence, 80.3% (27%) for metachronous cancer, 7% (0%) for recurrence of synchronous cancers and 0% (0%) for lung metastasis after a solitary primary lung cancer.

从1990年到2000年,9600例肺癌患者中有2268例(29.9%)接受了I期至IIIA期非小细胞肺癌切除术。100例(3.5%)患者进行了再干预,27例为局部复发,42例为异时性肿瘤,31例为转移或第三肿瘤。对23名患者进行了第三次干预,对2名患者进行了第四次干预。住院死亡率为9%。5年和10年的总生存率分别为31.9%和17.9%。首次干预(再干预)后,局部复发的5年生存率为26%(11%),异时性癌症为80.3%(27%),同步性癌症复发为7%(0%),单发原发性肺癌后肺转移为0%(0%)。
{"title":"[What can thoracic surgery accomplish in recurrent/second carcinoma of non-small-cell bronchial carcinoma?].","authors":"P Wex,&nbsp;E Utta,&nbsp;V Haas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>From 1990 to 2000, 2268 (29.9%) of 9600 lung cancer patients underwent resection for stage I to IIIA non-small cell lung cancer. Reinterventions were done in one hundred (3.5%) patients, for locoregional recurrence in 27, metachronous cancer in 42, metastasis or a third tumor in 31. A third intervention was performed in 23 patients and a fourth in two. The in-hospital mortality rate was 9%. The overall survival was 31.9% at five and 17.9% at ten years. The 5-year survival after the first intervention (reintervention) was 26% (11%) for local recurrence, 80.3% (27%) for metachronous cancer, 7% (0%) for recurrence of synchronous cancers and 0% (0%) for lung metastasis after a solitary primary lung cancer.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"785-91"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22349024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Development of primary malignancies after liver and kidney transplantation and the treatment approach]. [肝肾移植术后原发性恶性肿瘤的发展及治疗方法]。
W O Bechstein, K Dette, M Golling, Ch Wullstein

Primary malignancy after solid organ transplantation has a more than three-fold incidence compared to the normal population. Causes are intensity and duration of immunosuppression, pre-operatively undetected, occult malignancy or pre-cancerous lesions in the recipient, direct or indirect tumor transmission via the transplant and environmental factors. Measures for prevention comprise antiviral treatment of individuals at risk for primary EBV-infection and prevention of sun exposure. Early detection follows general medical guidelines and, in addition, selective screening of certain risk groups of patients. Treatment of solid tumors follows established guidelines of professional working parties. Post-transplant lymphoproliferative disorders can often be treated with anti-CD antibody (rituximab). Antiproliferative immunosuppressants like rapamycin may seem promising with regard to a possibly reduced incidence of de-novo malignancy in the future.

实体器官移植后原发性恶性肿瘤的发生率是正常人群的三倍以上。原因包括免疫抑制的强度和持续时间、术前未被发现、受体存在隐匿的恶性或癌前病变、通过移植直接或间接的肿瘤传播以及环境因素。预防措施包括对有原发性eb病毒感染风险的个体进行抗病毒治疗和防止日晒。早期发现遵循一般医疗准则,此外,对某些危险患者群体进行选择性筛查。实体瘤的治疗遵循专业工作组的既定指导方针。移植后淋巴细胞增生性疾病通常可以用抗cd抗体(利妥昔单抗)治疗。抗增殖性免疫抑制剂如雷帕霉素在未来可能降低恶性肿瘤复发的发生率方面似乎很有希望。
{"title":"[Development of primary malignancies after liver and kidney transplantation and the treatment approach].","authors":"W O Bechstein,&nbsp;K Dette,&nbsp;M Golling,&nbsp;Ch Wullstein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary malignancy after solid organ transplantation has a more than three-fold incidence compared to the normal population. Causes are intensity and duration of immunosuppression, pre-operatively undetected, occult malignancy or pre-cancerous lesions in the recipient, direct or indirect tumor transmission via the transplant and environmental factors. Measures for prevention comprise antiviral treatment of individuals at risk for primary EBV-infection and prevention of sun exposure. Early detection follows general medical guidelines and, in addition, selective screening of certain risk groups of patients. Treatment of solid tumors follows established guidelines of professional working parties. Post-transplant lymphoproliferative disorders can often be treated with anti-CD antibody (rituximab). Antiproliferative immunosuppressants like rapamycin may seem promising with regard to a possibly reduced incidence of de-novo malignancy in the future.</p>","PeriodicalId":81771,"journal":{"name":"Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress","volume":"119 ","pages":"398-404"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22349319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1