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Comparative Study of Treatments of Children with ADHD with Medication Alone Vs Medication with Cognitive Behavioral Therapy 单独用药与认知行为疗法治疗儿童多动症的比较研究
Pub Date : 2018-10-05 DOI: 10.26502/JPPD.2572-519X0047
Z. Alina, Abida Niazi, Ambreen Mehmood, H. Ijaz, Abida Hussain, Sabika Zaheer, H. Nasar, H. Shahid, F. Sundus, S. Nawaz, R. Zaheer
This study is important due to the long terms negative effects of using stimulants for ADHD therapy as they manifest negative side effects. The amphetamine stimulants are neurotoxic with long-terms use and it’s imperative to use it in lower dosages while at the same time yielding the maximum affects to treat ADHD symptoms. This narrative review is conducted to explore the professional literature between 2000-2015. The trials conducted to explore the efficacy of adjunctive therapy with stimulants demonstrated various results. The supplementation of combined magnesium and vitamin B6 yielded positive results with significant improvement in ADHD, specifically in hyperactivity, aggression, and low attention span. Zinc supplementation, with 30 mg or more, with amphetamine aided in lowering the dosage of amphetamine use by at least 20% while yielding the same results compared to higher amphetamine use without zinc. Zinc + methylphenidate combination yielded positive results to lower ADHD symptoms; however the results are not conclusive due to more trials are needed in different dosages of zinc. Based on the clinical studies, dietary supplements are useful in treating ADHD symptoms. Clinical trials with zinc and magnesium+B6 have shown to yield positive results in lowering the ADHD symptoms. With current ADHD therapy, continued stimulant use leads to tolerance and increases with continued use; hence the stimulant dosage also needs to be increased to reach efficacy. Adding adjunctive dietary supplements have demonstrated that the stimulant dosages can be lowered. However, further study is needed to factor in bioavailability, efficacy of other dosages, diet, and any other factors that could hinder the function of the dietary supplements internally.
这项研究很重要,因为长期使用兴奋剂治疗多动症的负面影响,因为它们表现出负面的副作用。长期使用安非他命兴奋剂对神经有毒性,因此必须在治疗ADHD症状时减少剂量,同时产生最大的效果。本文对2000-2015年间的专业文献进行了叙述性回顾。为探索兴奋剂辅助治疗的疗效而进行的试验显示了各种结果。镁和维生素B6的联合补充对多动症,特别是多动症,攻击性和注意力不集中的显著改善产生了积极的效果。与不加锌的高剂量安非他明相比,加锌30毫克或更多的安非他明有助于将安非他明的用量降低至少20%,同时产生相同的结果。锌+哌甲酯联用对降低ADHD症状有积极效果;然而,由于需要对不同剂量的锌进行更多的试验,结果并不是决定性的。根据临床研究,膳食补充剂对治疗ADHD症状是有用的。临床试验表明,锌和镁+B6在减轻多动症症状方面产生了积极的结果。在目前的ADHD治疗中,持续使用兴奋剂会导致耐受性,并随着持续使用而增加;因此,兴奋剂的剂量也需要增加,以达到疗效。添加辅助性膳食补充剂已经证明可以降低兴奋剂的剂量。然而,需要进一步的研究来考虑生物利用度、其他剂量的功效、饮食和任何其他可能阻碍膳食补充剂内部功能的因素。
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引用次数: 0
Synthesis, spectral characterization, molecular structure, HOMO-LUMO, MEP and NLO analysis of some (E)-N-(4-Fluoro-3-Phenoxybenzylidene)- substituted benzenamines 一些(E)- n -(4-氟-3-苯氧基苄基)取代苯胺的合成、光谱表征、分子结构、HOMO-LUMO、MEP和NLO分析
Pub Date : 2016-11-23 DOI: 10.14419/IJAC.V4I2.6742
G. Raj, P. Jayanthi, M. Sekar
In this work, (E)-N-(4-Fluoro-3-Phenoxybenzylidene)-substituted benzenamines (1-6) have been synthesized and characterized by IR, 1 H and 13 C NMR spectral studies. Density functional theory (DFT) has been used to optimize geometrical parameters, atomic charges, vibrational wavenumbers and intensity of vibrational bands. The molecular properties HOMO-LUMO, MEP and atomic charges of carbon, nitrogen and oxygen were calculated using B3LYP/6-311G (d, p) basis set. The polarizability and first order hyperpolarizability of the title Compounds were calculated and interpreted.
本文合成了(E)- n -(4-氟-3-苯氧苄基)-取代苯胺(1-6),并通过IR、1h和13c NMR对其进行了表征。密度泛函理论(DFT)已被用于优化几何参数、原子电荷、振动波数和振动带强度。采用B3LYP/6-311G (d, p)基集计算了碳、氮、氧的分子性质HOMO-LUMO、MEP和原子电荷。计算并解释了标题化合物的极化率和一阶超极化率。
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引用次数: 0
Import risk assessment of hatching eggs and day old chicks via Khartoum International Airport, Sudan 经苏丹喀土穆国际机场的孵化蛋和日龄雏鸡进口风险评估
Pub Date : 2011-12-30 DOI: 10.5897/JCAB11.050
Ahmed Abdelgadir Berier, A. E. Abdelgadir
This study was aimed to assess the quality level of the Sudanese standards and risks associated with the importation of hatching eggs and day old chicks as well as the sanitary measures in place based on the international (OIE) standards. Data were collected from the Federal Ministry of Animal Resources and Fisheries (FMARF), the Sudanese Standards and Metrology Organization (SSMO) and from World Animal Health Organization (OIE). For that purpose, risk assessment was used as described in Section 2 of the (OIE, 2009). The results showed that a total of (11,241,209) chicks, and (62,3070,30) layers and broilers hatching eggs were imported into the Sudan during the period 2005 to 2009 from 14 countries, which may comprise potential risk of introducing avian influenza (AI) and many other diseases into the country. In viewing the poultry health status in the exporting counties, the avian influenza is endemic in Egypt, which represented the main exporting country of the two commodities in 2005. In 2006, about 18.3% (out of 235,626 susceptible population) were infected with avian influenza (AI) and 43.2% (n = 101,814) were destroyed for the same reason. Moreover, the Sudanese standards of hatching eggs and day old chicks had not been set according to scientifically based risk estimations and the sanitary measures in place were less stringent to achieve the appropriate level of protection. Therefore, a multidisciplinary scientific risk analysis following OIE standards are recommended for the importation procedures and setting the Sudanese standards.
本研究旨在评估苏丹标准的质量水平和与进口孵化蛋和日龄雏鸡相关的风险,以及根据国际兽疫局标准采取的卫生措施。数据收集自联邦动物资源和渔业部(FMARF)、苏丹标准与计量组织(SSMO)以及世界动物卫生组织(OIE)。为此,采用了《世界动物卫生组织,2009》第2节所述的风险评估方法。结果表明,2005年至2009年期间,苏丹共从14个国家进口了(11,241,209)只雏鸡和(62,3070,30)只蛋鸡和正在孵蛋的肉鸡,这可能存在将禽流感和许多其他疾病引入该国的潜在风险。从出口国的家禽健康状况来看,禽流感在埃及流行,埃及是2005年这两种商品的主要出口国。2006年,约18.3%(在235 626名易感人口中)感染了禽流感,43.2% (n = 101,814)因同样原因被销毁。此外,苏丹的孵化蛋和日龄雏鸡的标准没有根据科学的风险估计制定,现有的卫生措施也不太严格,无法达到适当的保护水平。因此,建议按照世界动物卫生组织的标准对进口程序和制定苏丹标准进行多学科科学风险分析。
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引用次数: 2
Determination of groundwater flow direction in Utagba-Ogbe Kingdom, Nokwa Land Area of Delta State, Nigeria. 尼日利亚三角洲州Nokwa地区Utagba-Ogbe王国地下水流向的测定。
Pub Date : 2010-01-01 DOI: 10.3923/OJESCI.2010.32.34
Oseji, J. Otutu, Merrious Oviri Ofomola
A study was carried out in Utagba-Ogbe Kingdom, Ndokwa west Local Government Area of Delta State using the global positioning system (GPS) and meter tape to determine the groundwater flow pattern of the area. The longitudes, latitudes and elevations of six locations evenly distributed within the kingdom were measured and recorded. The depths to the water level in the hand-dug wells were measured directly with the aid of a meter tape. The water elevation contour map of Utagba-Ogbe Kingdom revealed that groundwater flow direction is toward the Eastern part of the kingdom. It is therefore recommended that dumpsites should be sited within the Eastern part of the kingdom while boreholes for potable groundwater exploitation could be sited in the north, south and western regions of the kingdom to minimize groundwater contamination. In the event of pollution groundwater within the Eastern regions of Utagba-Ogbe Kingdom are densely contaminated. Therefore, communities within the North, West and Southern regions of Utagba- Ogbe Kingdom should take steps to ensure that land use activities will not pose a threat on the quality of groundwater. The present study act as a guide for future groundwater exploration, hence the information will be useful to both the Government and Individuals especially those in water industries in sinking and maintaining boreholes for optimum groundwater exploitation.
在三角洲州恩多克瓦西部地方政府区Utagba-Ogbe王国进行了一项研究,使用全球定位系统(GPS)和米带确定该地区的地下水流动模式。对全国分布均匀的六个地点的经度、纬度和海拔进行了测量和记录。手挖井的水位深度是借助米尺直接测量的。乌塔格巴-奥格贝王国的高程等高线图显示,地下水流向王国东部。因此,建议将倾倒场设在王国的东部,而开采饮用地下水的钻孔可设在王国的北部、南部和西部地区,以尽量减少地下水污染。如果发生污染,乌塔格巴-奥格贝王国东部地区的地下水受到严重污染。因此,乌塔格巴-奥格贝王国北部、西部和南部地区的社区应采取措施,确保土地利用活动不会对地下水质量构成威胁。本研究可作为未来地下水勘探的指南,因此所得资料对政府和个人,特别是水工业的业者,在挖掘和维持钻孔以达到最佳的地下水开采方面,将是有用的。
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引用次数: 17
Advances In Manufacturing Technology 制造技术的进步
Pub Date : 1986-01-01 DOI: 10.1007/978-1-4615-8524-4
G. MeghanaShivani., G. Venkateswarlu, R. Sharada
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引用次数: 45
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