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Methodological Concerns Regarding Cost-effectiveness Analysis of Palivizumab in Florida Medicaid-Reply. 对佛罗里达州医疗补助中帕利珠单抗成本-效果分析的方法学关注-回复。
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2012.1594
Christian Hampp, Teresa L Kauf, Arwa S Saidi, Almut G Winterstein
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引用次数: 1
About this journal. 关于这本日记。
Pub Date : 2012-10-01 DOI: 10.1001/archpedi.166.10.887
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引用次数: 0
The Pleiades, or Seven Sisters (Messier object 45), which is an open star cluster in the constellations of Taurus. Taken at Anza, California. 昴宿星团,又称七姐妹星团(梅西耶45号天体),是金牛座中的一个疏散星团。摄于加州安扎。
Pub Date : 2012-10-01 DOI: 10.1001/2013.jamapediatrics.22
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引用次数: 0
Television viewing and externalizing problems in preschool children: the Generation R Study. 学龄前儿童的电视观看和外化问题:R世代研究。
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2012.653
Marina Verlinden, Henning Tiemeier, James J Hudziak, Vincent W V Jaddoe, Hein Raat, Mònica Guxens, Albert Hofman, Frank C Verhulst, Pauline W Jansen

Objective: To determine whether the amount, type, and patterns of television viewing predict the onset or the persistence of externalizing problems in preschool children.

Design: Longitudinal study of a prospective population-based cohort in the Netherlands.

Setting: Parents reported time of television exposure and type of programs watched by children. Externalizing problems were assessed using the Child Behavior Checklist at 18 and 36 months.

Participants: A population-based sample of 3913 children.

Main exposure: Television viewing time, content, and patterns of exposure (at 24 and 36 months) in children with and without preexisting problems to assess the incidence and persistence of externalizing problems.

Main outcome measures: Externalizing problems at 36 months.

Results: Program content and time of television exposure assessed at 24 months did not predict the incidence of externalizing problems at 36 months (odds ratio, 2.24; 95% CI, 0.97-5.18). However, the patterns of exposure over time reflecting high levels of television viewing were associated with the incidence of externalizing problems (odds ratio, 2.00; 95% CI, 1.07-3.75) and the persistence of the preexisting externalizing problems (2.59; 1.03-6.55).

Conclusions: Our study showed that high television exposure increases the risk of the incidence and the persistence of externalizing problems in preschool children.

目的:探讨学龄前儿童看电视的数量、类型和模式是否能预测外化问题的发生或持续。设计:荷兰前瞻性人群队列的纵向研究。设置:父母报告孩子看电视的时间和观看的节目类型。在18个月和36个月时使用儿童行为检查表评估外化问题。参与者:以人群为基础的3913名儿童样本。主要暴露:有和没有先前存在问题的儿童的电视观看时间、内容和暴露模式(24和36个月),以评估外化问题的发生率和持久性。主要观察指标:36个月时问题外部化。结果:24个月时评估的电视节目内容和时间不能预测36个月时外化问题的发生率(优势比为2.24;95% ci, 0.97-5.18)。然而,随着时间的推移,反映高水平电视观看的暴露模式与外部化问题的发生率有关(优势比,2.00;95% CI, 1.07-3.75)和先前存在的外化问题的持久性(2.59;1.03 - -6.55)。结论:我们的研究表明,高电视暴露增加了学龄前儿童外化问题发生率和持久性的风险。
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引用次数: 48
Children's environmental health. 儿童环境卫生。
Pub Date : 2012-10-01 DOI: 10.1001/2013.jamapediatrics.8
Megan A Moreno, Fred Furtner, Frederick P Rivara
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引用次数: 0
Nothing is free in life--not even prevention! 生活中没有什么是免费的——即使是预防!
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2012.1141
Paul S Casamassimo
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引用次数: 1
This month in archives of pediatrics & adolescent medicine. 这个月在儿科和青少年医学档案。
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2011.554
I n their study van der Aa et al (page 509) found that more of the variation in sedentary behavior among 20-year-old individuals was accounted for by genetics (48% for males and 34% for females) and nonshared environmental factors (52% for males and 66% for females) than it was for 12-year-old adolescents (35% for males and 19% for females by genetics and 36% for males and 34% for females by nonshared environmental factors). Conversely, shared environmental factors played less of a role in late adolescence.
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引用次数: 0
Use of olive oil for the treatment of seborrheic dermatitis in children. 使用橄榄油治疗儿童脂溢性皮炎。
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2012.765
Elaine Siegfried, Erica Glenn
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引用次数: 15
Urban Latino children's physical activity levels and performance in interactive dance video games: effects of goal difficulty and goal specificity. 拉丁美洲城市儿童体育活动水平和互动舞蹈视频游戏的表现:目标难度和目标特异性的影响。
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2012.649
Zan Gao, Leslie Podlog

Objective: To examine the effects of different levels of goal specificity and difficulty on Latino children's performance and physical activity (PA) levels in an after-school program incorporating an interactive dance program (Dance Dance Revolution [DDR]; Konami Corporation).

Design: Comparison study.

Setting: Rose Park Elementary School, Salt Lake City, Utah.

Participants: Ninety-eight Latino children in the first through sixth grades, aged 7 to 13 years.

Intervention: After the pretest, the participants were randomly assigned into 1 of the following 3 goal-setting conditions: (1) easy, (2) difficult, and (3) best effort (hereinafter referred to as do-your-best goal).

Main outcome measures: Participants' PA levels were measured using piezoelectric pedometers, and steps per minute were used as the outcome variable. Participants' total points for their dance on television screens were retrieved as their performance scores. These outcome variables were assessed again 8 weeks later (posttest score).

Results: The multivariate analysis of covariance yielded a significant main effect for the goal-setting condition. Follow-up tests revealed that children who set specific (easy or difficult) goals had significantly greater increased PA levels (mean scores, 10.34 for easy and 22.45 for difficult) and DDR performance (0.011 for easy and 0.67 for difficult) than those in the do-your-best group (0.83 for PA and 0.17 for performance). In addition, children's increased PA levels in the difficult-goal group were significantly higher than those in the easy-goal group.

Conclusions: The easy- and difficult-goal groups show a significant improvement on DDR performance. The difficult- goal group also displays the highest improvement on PA levels. Strategies to enhance children's DDR performance and PA levels are discussed in relation to the extant goal-setting literature.

目的:探讨不同水平的目标特异性和难度对拉丁裔儿童在一个包含互动舞蹈项目的课外活动中的表现和身体活动(PA)水平的影响。科乐美公司)。设计:比较研究。地点:犹他州盐湖城玫瑰公园小学。参与者:98名7至13岁的一至六年级拉丁裔儿童。干预:在预测后,参与者被随机分配到以下3个目标设定条件中的一个:(1)容易,(2)困难,(3)尽力而为(以下简称尽力而为目标)。主要结果测量:使用压电计步器测量参与者的PA水平,每分钟步数作为结果变量。参与者在电视屏幕上跳舞的总分作为他们的表演分数被检索出来。8周后再次评估这些结果变量(测试后得分)。结果:多变量协方差分析对目标设定条件有显著的主效应。后续测试显示,设定具体(简单或困难)目标的儿童的PA水平(平均得分,简单10.34分,困难22.45分)和DDR表现(简单0.011分,困难0.67分)显著高于尽力而为组(PA 0.83分,表现0.17分)。此外,困难目标组儿童的PA水平显著高于容易目标组。结论:易目标组和难目标组在DDR表现上有显著改善。难度目标组在PA水平上也表现出最高的进步。本文结合现有的目标设定文献,讨论了提高儿童DDR绩效和PA水平的策略。
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引用次数: 26
Infections in pediatric postdiarrheal hemolytic uremic syndrome: factors associated with identifying shiga toxin-producing Escherichia coli. 儿童腹泻后溶血性尿毒症综合征的感染:与鉴定产志贺毒素大肠杆菌相关的因素
Pub Date : 2012-10-01 DOI: 10.1001/archpediatrics.2012.471
Rajal K Mody, Ruth E Luna-Gierke, Timothy F Jones, Nicole Comstock, Sharon Hurd, Joni Scheftel, Sarah Lathrop, Glenda Smith, Amanda Palmer, Nancy Strockbine, Deborah Talkington, Barbara E Mahon, Robert M Hoekstra, Patricia M Griffin

Objective: To describe pathogens identified through routine clinical practice and factors associated with identifying Shiga toxin-producing Escherichia coli (STEC) infection in patients with postdiarrheal hemolytic uremic syndrome (DHUS).

Design: Population-based active surveillance.

Setting: Hospitals in the FoodNet surveillance areas from 2000 through 2010.

Participants: Children younger than 18 years with DHUS.

Main exposures: Testing for STEC and demographic and clinical characteristics.

Main outcome measures: Percentage of patients with evidence of infection with likely HUS-causing agents and associations between exposures and evidence of STEC infection.

Results: Of 617 patients, 436 (70.7%) had evidence of infection with likely HUS-causing agents: STEC O157 (401 patients), non-O157 STEC (21 patients), O157 and non-O157 STEC (1 patient), Streptococcus pneumoniae (11 patients), and other pathogens (2 patients). Among patients without microbiological evidence of STEC, 76.9% of those tested had serologic evidence of STEC infection. Children more likely to have evidence of STEC infections included those patients tested for STEC less than 4 days after diarrhea onset, 12 months or older (71.6% vs 27.8% if <12 months of age), with infections as part of an outbreak (94.3% vs 67.3%), with bloody diarrhea (77.2% vs 40.4%), with onset during June through September (76.9% vs 60.1%), with a leukocyte count greater than 18 000/μL (to convert to ×10(9)/L, multiply by 0.001) (75.7% vs 65.3%), or with only moderate anemia (hemoglobin 7.0 g/dL [to convert to grams per liter, multiply by 10] or hematocrit greater than 20% [to convert to a proportion of 1, multiply by 0.01]) (75.1% vs 66.3%). However, many of these associations were weaker among children with thorough STEC testing.

Conclusions: Early stool collection for E coli O157 culture and Shiga toxin testing of all children with possible bacterial enteric infection will increase detection of STEC strains causing HUS. In the absence of microbiological evidence of STEC, serologic testing should be performed.

目的:描述在腹泻后溶血性尿毒症(DHUS)患者中通过常规临床实践鉴定出的致病菌以及鉴定产志贺毒素大肠杆菌(STEC)感染的相关因素。设计:基于人群的主动监测。环境:2000年至2010年食品网监测区域的医院。参与者:18岁以下DHUS患儿。主要暴露:产志贺毒素大肠杆菌检测及人口学和临床特征。主要结局指标:有证据表明感染可能引起尿毒综合征的病原体的患者百分比以及暴露与产志贺毒素大肠杆菌感染证据之间的关联。结果:在617例患者中,436例(70.7%)有证据表明感染了可能引起胡斯综合征的病原体:STEC O157(401例)、非O157 STEC(21例)、O157和非O157 STEC(1例)、肺炎链球菌(11例)和其他病原体(2例)。在没有产志贺毒素大肠杆菌微生物学证据的患者中,76.9%的检测者有产志贺毒素大肠杆菌感染的血清学证据。更可能有产志贺毒素大肠杆菌感染证据的儿童包括腹泻发病后不到4天、12个月或更大的产志贺毒素大肠杆菌检测患者(71.6% vs 27.8%)。结论:早期收集粪便进行大肠杆菌O157培养和志贺毒素检测所有可能的肠道细菌感染儿童将增加检测出引起溶血性尿毒综合征的产志贺毒素大肠杆菌菌株。在没有产志贺毒素大肠杆菌微生物证据的情况下,应进行血清学检测。
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引用次数: 42
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Archives of pediatrics & adolescent medicine
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