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An approach to the upper airway evaluation in pediatric persistent obstructive sleep apnea. 儿童持续性阻塞性睡眠呼吸暂停的上呼吸道评估方法。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-11-02 DOI: 10.5546/aap.2023-10117.eng
María V Demarchi, Federico Herranz, Cinthia Pérez, Carlos S López, Carla Pereyra

In pediatrics, obstructive sleep apnea syndrome (OSAS) is a disorder associated with multiple consequences at the cognitive and behavioral level. The main associated risk factor is the presence of tonsillar hypertrophy and adenoids. An adenotonsillectomy is the first-line treatment. The incidence of persistent OSAS varies from 15% to 75%, depending on comorbidities. This is a challenge in terms of management; it requires a comprehensive approach for an adequate diagnosis and treatment. The objective of this bibliographic review is to propose a diagnostic and therapeutic approach for persistent OSAS.

在儿科,阻塞性睡眠呼吸暂停综合征(OSAS)是一种与认知和行为水平的多种后果相关的疾病。主要的相关危险因素是扁桃体肥大和腺样体的存在。腺扁桃体切除术是一线治疗方法。根据合并症的不同,持续性OSAS的发生率从15%到75%不等。这在管理方面是一个挑战;它需要一种全面的方法来进行充分的诊断和治疗。本文献综述的目的是提出一种持续性OSAS的诊断和治疗方法。
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引用次数: 0
Resistance to integrase inhibitors in children with vertically-transmitted human immunodeficiency virus: First cases in Uruguay. 垂直传播人类免疫缺陷病毒感染儿童对整合酶抑制剂的抗药性:乌拉圭的首例病例。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-06-01 DOI: 10.5546/aap.2023-02992.eng
Ana V González Castro, Verónica Sande, Lorena V Pardo Casaretto, Stella I Gutiérrez Rodríguez

Antiretroviral (ARV) drug resistance is a public health issue. Resistance has also been observed in the case of integrase strand transfer inhibitors (INSTIs) used in pediatrics. The objective of this article is to describe 3 cases of INSTI resistance. These are the cases of 3 children with vertically-transmitted human immunodeficiency virus (HIV). They were started on ARVs as infants and preschoolers, with poor treatment adherence, and had different management plans due to associated comorbidities and virological failure due to resistance. In the 3 cases, resistance developed rapidly as a result of virological failure and INSTI involvement. Treatment adherence should be monitored so that any increase in viremia can be detected early. Virological failure in a patient treated with raltegravir forces to a rapid change in ARV therapy because its continued use may favor new mutations and resistance to second-generation INSTIs.

抗逆转录病毒(ARV)耐药性是一个公共卫生问题。儿科使用的整合酶链转移抑制剂(INSTIs)也出现了耐药性。本文旨在描述 3 例 INSTI 耐药性病例。这是 3 例垂直传播人类免疫缺陷病毒(HIV)的儿童病例。他们从婴儿和学龄前儿童开始接受抗逆转录病毒药物治疗,治疗依从性差,由于相关合并症和耐药导致的病毒学失败,他们的治疗方案各不相同。在这 3 个病例中,由于病毒学失败和 INSTI 的参与,耐药性发展迅速。应监测治疗的依从性,以便及早发现病毒血症的增加。使用拉替拉韦治疗的患者如果出现病毒学失败,就必须迅速更换抗逆转录病毒疗法,因为继续使用拉替拉韦可能会产生新的突变,并对第二代 INSTI 产生耐药性。
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引用次数: 0
Assessment of children's physical fitness and school health in the province of San Luis, Argentina. 阿根廷圣路易斯省儿童体质和学校健康评估。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-08-17 DOI: 10.5546/aap.2022-02975.eng
Damián E Aimar, Alicia Bañuelos, Juliana Menéndez, Yamir de Las Mercedes García López, Karim A Neme, María B Magallanes, Gastón C García

Introduction. The assessment of physical fitness (PF), is useful strategy to know the current status of schoolchildren. Our primary objective was to measure the current health status and PF levels of schoolchildren in San Luis and to develop PF reference tables. Population and methods. Schoolchildren aged 9 to 12 years (boys and girls) were assessed based on 2 health indicators: body mass index and blood pressure. PF was measured using the ALPHA-Fitness test battery. Blood pressure, body mass, height, foot and hand length, standing long jump, 30 m sprint, 4 × 10 m agility test, and 20 m shuttle run test were assessed. The body mass index (BMI) and biological maturation were estimated. Results. A total of 15 548 schoolchildren were assessed. Average systolic blood pressure was 101 ± 10 mmHg and diastolic blood pressure, 66 ± 7 mmHg; BMI: 20.2 ± 4.3 kg/m 2 . Average PF was, in the cardiorespiratory component, VO2 max.: 39.87 ± 3.2 mL/kg/min and speed reached during the 20 m shuttle run test: 8.9 ± 0.6 km/h; in the musculoskeletal component, standing long jump: 120.6 ± 23.9 cm, 30 m sprint: 6.56 ± 0.85 s, 4 × 10 m agility test: 15.17 ± 1.82 s. The performance was better in the boys group (p < 0.001). Conclusion. Blood pressure was normal. Fifty percent of the sample was overweight or obese as per their BMI. Both boys and girls showed low PF levels. PF reference tables for schoolchildren from San Luis were developed for the first time.

引言体能(PF)评估是了解学童现状的有用策略。我们的首要目标是测量圣路易斯市学龄儿童的健康现状和体能水平,并编制体能参考表。人群和方法。我们根据体重指数和血压这两项健康指标对 9 至 12 岁的学龄儿童(男孩和女孩)进行了评估。PF采用ALPHA-Fitness测试电池进行测量。对血压、体重、身高、手脚长度、立定跳远、30 米短跑、4 × 10 米敏捷性测试和 20 米往返跑测试进行了评估。还估算了体重指数(BMI)和生物成熟度。结果共对 15 548 名学童进行了评估。平均收缩压为 101 ± 10 mmHg,舒张压为 66 ± 7 mmHg;体重指数为 20.2 ± 4.3 kg/m 2。在心肺功能方面,最大容氧量为 39.87 ± 3.2 毫升/千克/分钟,20 米往返跑测试速度为 8.9 ± 0.6 千米/小时;在肌肉骨骼功能方面,立定跳远的平均速度为 120.6 ± 23.9 厘米:120.6 ± 23.9 厘米,30 米短跑:6.56 ± 0.85 秒,4 × 10 米敏捷性测试:男生组的成绩更好(P < 0.001)。结论血压正常。根据体重指数,50%的样本超重或肥胖。男孩和女孩的 PF 值均较低。首次为圣路易斯的学龄儿童制定了血压参考表。
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引用次数: 0
Evaluación de la usabilidad de la teleconsulta durante la pandemia por COVID-19 en un hospital pediátrico 评估一家儿科医院在 COVID-19 大流行期间远程会诊的可用性
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 DOI: 10.5546/aap.2023-10163
Comunicación Breve, Romina Ledesma, P. Domínguez, Emiliano Gigliotti, M. E. Ibarra
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引用次数: 0
Prevalence of osteopenia of prematurity before and after implementing an early strategy with the use of calcium and phosphate. 使用钙和磷酸盐的早期策略实施前后早产儿骨质疏松的患病率。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-08-17 DOI: 10.5546/aap.2023-03001.eng
Maria P Carrascal Gutiérrez, María C Janis, Pablo H Brener Dik, María F Galletti, Gonzalo L Mariani

Introduction. With the use of aggressive parenteral nutrition in very low birth weight infants, alterations in calcium and phosphate metabolism were detected. In 2016, a prevention strategy was implemented through calcium phosphate monitoring and early supplementation. Our objective was to study whether this strategy reduces the prevalence of osteopenia and to identify associated risk factors. Population and methods. Quasi-experiment comparing the prevalence of osteopenia between two groups: one after implementing the calcium phosphate monitoring and supplementation strategy (01/01/2017-12/31/2019) and another prior to such intervention (01/01/2013-12/31/2015). Results. A total of 226 patients were included: 133 in the pre-intervention period and 93 in the post-intervention period. The overall prevalence of osteopenia was 26.1% (95% CI: 20.5-32.3) and it was reduced from 29.3% (95% CI: 21.7-37.8) in the pre-intervention period to 21.5% (95% CI: 13.6-31.2) in the post-intervention period, with no statistical significance (p = 0.19). In the multivariate analysis, the NEOCOSUR score for risk of death at birth, use of postnatal corticosteroids, and the intervention period were independently associated with osteopenia. Being born after the intervention reduced the probability of alkaline phosphatase > 500 IU/L by 71%, regardless of the other variables included in the model. Conclusion. Calcium phosphate monitoring and early supplementation is a protective factor against the development of osteopenia in very low birth weight infants.

简介在对极低出生体重儿使用积极的肠外营养时,发现了钙和磷代谢的改变。2016 年,通过磷酸钙监测和早期补充实施了一项预防策略。我们的目的是研究这一策略是否降低了骨质疏松症的发病率,并找出相关的风险因素。研究对象和方法比较两组人群的骨质疏松症患病率的准实验:一组在实施磷酸钙监测和补充策略后(01/01/2017-12/31/2019),另一组在实施该干预前(01/01/2013-12/31/2015)。结果。共纳入 226 名患者:其中 133 人在干预前,93 人在干预后。骨质疏松症的总发病率为 26.1%(95% CI:20.5-32.3),从干预前的 29.3%(95% CI:21.7-37.8)降至干预后的 21.5%(95% CI:13.6-31.2),但无统计学意义(P = 0.19)。在多变量分析中,出生时死亡风险的 NEOCOSUR 评分、产后使用皮质类固醇和干预期与骨质疏松症有独立关联。无论模型中是否包含其他变量,干预后出生的婴儿碱性磷酸酶大于 500 IU/L 的概率降低了 71%。结论监测并及早补充磷酸钙是防止极低出生体重儿患骨质疏松症的一个保护因素。
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引用次数: 0
Pylephlebitis in pediatrics: A diagnostic challenge. 儿科静脉炎:诊断难题。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-06-01 DOI: 10.5546/aap.2022-02934.eng
Dolores Artese, Juana I Romero, Natalia P Álvarez, Guillermo N Ledo, Mariano N Lorenzo, Melina Perdiz, María V Cohen

Pylephlebitis is defined as suppurative thrombosis of the portal vein as a complication of abdominal infections. In pediatrics, the most frequent etiology is appendicitis, generally of late diagnosis, presenting as sepsis, with a high mortality rate. Imaging methods are necessary for diagnosis; the most common are the Doppler ultrasound and computed tomography angiography. Treatment is based on surgery, antibiotic therapy, and anticoagulation. The indication for the latter is controversial, but it may improve prognosis and decrease morbidity and mortality. Here we describe a clinical case of pylephlebitis secondary to Escherichia coli sepsis, which started as acute appendicitis in a pediatric patient who progressed to cavernomatous transformation of the portal vein. It is important to know the management of this disease because, once the initial symptoms are overcome, it will require close follow-up due to a potential progression to liver failure.

门静脉静脉炎是指门静脉化脓性血栓形成,是腹部感染的并发症。在儿科,最常见的病因是阑尾炎,一般诊断较晚,表现为败血症,死亡率很高。诊断需要影像学方法,最常见的是多普勒超声和计算机断层扫描血管造影。治疗以手术、抗生素治疗和抗凝为主。后者的适应症尚存争议,但可改善预后,降低发病率和死亡率。我们在此描述一例继发于大肠埃希菌败血症的幽门静脉炎临床病例,该病例起初为一名儿童患者的急性阑尾炎,后来发展为门静脉海绵状瘤变。了解这种疾病的治疗方法非常重要,因为一旦克服了最初的症状,就需要密切随访,因为这种疾病有可能发展为肝功能衰竭。
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引用次数: 0
Do the WHO head circumference standards underestimate microcephaly? 世界卫生组织的头围标准是否低估了小头畸形?
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-08-10 DOI: 10.5546/aap.2023-10127.eng
Mariana Del Pino
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引用次数: 0
The metaverse in the world of health: The present future. Challenges and opportunities. 健康世界中的元世界:当前的未来。挑战与机遇。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-05-18 DOI: 10.5546/aap.2022-02942.eng
Joia Nuñez, Laura Krynski, Paula Otero

The World Health Organization has defined "digital health" as the use of information and communication technologies to improve health. In recent years, there has been a strong acceleration in the adoption of these digital tools, which has had a major impact on traditional healthcare models. We are currently witnessing the emergence of a large immersive virtual environment called the "metaverse." Its emergence creates new and challenging opportunities in health care. This article explores some metaverse-related concepts, provides specific examples of its use in pediatrics, describes experiences in the hospital setting, and finally delves into the resulting challenges and opportunities.

世界卫生组织将 "数字健康 "定义为利用信息和通信技术改善健康。近年来,这些数字工具的应用速度明显加快,对传统的医疗保健模式产生了重大影响。目前,我们正在目睹一个被称为 "元宇宙 "的大型沉浸式虚拟环境的出现。它的出现为医疗保健领域带来了新的挑战性机遇。本文探讨了一些与元宇宙相关的概念,提供了在儿科使用元宇宙的具体实例,介绍了在医院环境中的体验,最后深入探讨了由此带来的挑战和机遇。
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引用次数: 0
Prenatal and postnatal exposure to tobacco smoke, nicotine, alcohol, marijuana, opioids, and illegal drugs. 产前和产后接触烟草烟雾、尼古丁、酒精、大麻、阿片类药物和非法药物。
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-08-03 DOI: 10.5546/aap.2023-10121.eng
Damián L Taire
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引用次数: 0
Assessment of the usability of teleconsultations during the COVID-19 pandemic at a children's hospital. COVID-19大流行期间儿童医院远程会诊的可用性评估
IF 0.8 4区 医学 Q3 Medicine Pub Date : 2024-02-01 Epub Date: 2023-12-07 DOI: 10.5546/aap.2023-10163.eng
Agustina Del R Sbruzzi, Romina Ledesma, Pablo Domínguez, Emiliano Gigliotti, Mariano E Ibarra

Introduction. Usability in a telemedicine system directly affects the efficiency and effectiveness of remote health care. Objective. To assess the usability of teleconsultations during the COVID-19 pandemic. Population and method. This was a cross-sectional study. The caregivers of children aged 1 month to 12 years were included. Usability was assessed with the Telehealth Usability Questionnaire, adapted to Spanish. Socioeconomic data were also assessed. Results. The response rate was 70.2% (n = 221). Most responders were women whose average age was 33 years, had completed secondary education and had public health insurance. Of them, 87.8% selected telephone health care and 88.2% had their first teleconsultation. The overall satisfaction was high, with lower scores for ease of use and learning how to use video calls. Conclusion. Regardless of modality, the usability of teleconsultations by caregivers of children aged 1 month to 12 years was adequate.

介绍。远程医疗系统的可用性直接影响远程医疗的效率和效果。目标。评估COVID-19大流行期间远程会诊的可用性。人口和方法。这是一项横断面研究。包括1个月至12岁儿童的照顾者。可用性评估与远程医疗可用性问卷,改编为西班牙语。社会经济数据也被评估。结果。有效率为70.2% (n = 221)。大多数答复者是平均年龄为33岁、完成中等教育并拥有公共医疗保险的妇女。其中,87.8%的人选择了电话保健,88.2%的人进行了第一次远程咨询。总体满意度很高,在易用性和学习如何使用视频通话方面得分较低。结论。无论采用何种方式,1个月至12岁儿童的护理人员远程咨询的可用性是充分的。
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引用次数: 0
期刊
Archivos argentinos de pediatria
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