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GENOTYPING STUDY ON HEPATITIS B VIRUS AMONG EGYPTIAN PATIENTS 埃及乙型肝炎病毒基因分型研究
Pub Date : 2022-08-01 DOI: 10.21608/amj.2022.255173
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引用次数: 0
OPTICAL COHERENCE TOMOGRAPHY PROGNOSTIC CRITERIA FOR INTRAVITREAL INJECTION OF ANTIVEGF IN DIABETIC MACULAR EDEMA 糖尿病性黄斑水肿玻璃体内注射抗vegf的光学相干断层成像预后标准
Pub Date : 2022-08-01 DOI: 10.21608/amj.2022.258339
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引用次数: 0
EVALUATION OF THE IMPACT OF HLA-G 14BP POLYMORPHISM ON THE SUSCEPTIBILITY OF HEPATITIS C VIRUS INFECTION IN EGYPTIAN PATIENTS HLA-g14bp多态性对埃及丙型肝炎病毒感染易感性的影响
Pub Date : 2022-08-01 DOI: 10.21608/amj.2022.258337
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引用次数: 0
PLATELET LEUKOCYTE AGGREGATES AS A PRO-THROMBOTIC RISK FACTOR IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE 炎症性肠病患者血小板白细胞聚集作为促血栓形成的危险因素
Pub Date : 2022-08-01 DOI: 10.21608/amj.2022.255190
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引用次数: 0
EVALUATION OF DIFFERENT ELASTOGRAPHY TECHNIQUES IN PREDICTION OF HEPATOCELLULAR CARCINOMA IN PATIENTS WITH HEPATITIS C RELATED LIVER CIRRHOSIS 不同弹性成像技术对丙型肝炎相关肝硬化患者肝细胞癌预测的评价
Pub Date : 2022-07-01 DOI: 10.21608/amj.2022.240695
Background: Although there has been significant improvement in the therapy for HCV achieving a high sustained virological response (SVR). The possibility of developing HCC remains approximately 1% per year after SVR in patients with liver cirrhosis. Objective: To evaluate the validity of different elastography techniques in prediction of presence of HCC in patients with chronic hepatitis C related liver cirrhosis. Patients and Methods: This study was a cross-sectional study conducted on Sixty (60) chronic hepatitis C patients (with or without cirrhosis or hepatocellular carcinoma). The studied patients were recruited from Al-Hussein
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引用次数: 0
IMPACT OF METABOLIC SYNDROME ON ANDROGEN/ ESTRADIOL RATIO, SEMEN PARAMETERS AND TESTICULAR VOLUME IN ADULTS 代谢综合征对成人雄激素/雌二醇比值、精液参数和睾丸体积的影响
Pub Date : 2022-07-01 DOI: 10.21608/amj.2022.240691
Background: Metabolic syndrome and the related co-morbidities can lead to impaired male reproductive function, including adverse effects on spermatogenesis and steroidogenesis as illustrated by reduced sperm number and quality, decreased testosterone levels and elevated inflammatory markers. Objective: To evaluate the impact of metabolic syndrome on androgen / estradiol ratio, semen parameters and testicular volume in adults. Patients and methods: This study was carried out on 60 adult males recruited from Al-Azhar University Hospitals outpatient clinics during the period between November 2016 and February 2021, divided into two equal groups: Group A: Males with the criteria of metabolic syndrome, and Group B: Males without the criteria of metabolic syndrome. All patients were subjected to: complete history taking, general and local examination, laboratory investigations (including total and free testosterone, serum estradiol, lipid profile, fasting blood glucose and Semen analysis) and scrotal duplex. Results: Significant decrease in both free and total testosterone in the metabolic group than the non-metabolic group. Significant inverse correlation between free testosterone / estadiol ratio and BMI, and an inverse but non statically significant correlation between free testosterone / estadiol ratio and waist circumference. Significant decrease was in both semen volume and total motility in the metabolic group than the non-metabolic group, with no statically significant difference in total sperm count, Sperm concentration, progressive motility or abnormal forms between both groups. Significant inverse correlation was found between semen volumes with BMI. Significant inverse correlation between total sperm count and sperm concentration with BMI. Significant inverse correlation was found between testicular volume on one side, and both BMI and waist circumference (WC) on the other side. Conclusion: Metabolic syndrome is directly related to a decrease in both free and total testosterone levels. Higher BMI is associated with decreased free testosterone/ estadiol ratio.
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引用次数: 0
MANAGEMENT OF THYROTOXICOSIS IN PREGNANCY 妊娠期甲状腺毒症的处理
Pub Date : 2022-07-01 DOI: 10.21608/amj.2022.240663
A. Mansour, Mohamed Sobhy Teamma, Osama, Fathy Ibrahim Al-Mezaien, A. Saeed
Background: Autoimmune GD (Graves' Disease) is the most common cause of hyperthyroidism in women of childbearing age. To prevent maternal and fetal complications, thyrotoxicosis during pregnancy should be adequately managed and controlled. The physiological adaptations associated with pregnancy challenge the assessment of thyroid function in pregnant women, and the treatment with antithyroid drugs (ATD) raises concerns for the pregnant woman and the fetus. Our aim of this study was to discuss the effect of hyperthyroidism on pregnancy, different methods of diagnosis of hyperthyroidism and treatment of hyperthyroidism during pregnancy for a favorable maternal health and fetal outcome. Objective: To discuss thyrotoxicosis this affects the pregnant woman and the effect of hyperthyroidism on pregnancy. It is to discuss different methods of diagnosis of hyperthyroidism during pregnancy. Also it is to study the treatment of hyperthyroidism and thyrotoxicosis during pregnancy for a favorable maternal health and fetal outcome. Patients and Methods: A prospective randomized clinical study that was conducted on 20 pregnant female patients with thyrotoxicosis in different stages of pregnancy attending Bab-El Shaaria and El-Hussein University Hospitals through the period from April (2020) to December (2020). The selected patients received one of the two main medications which are propyl-thiouracil (PTU) and methimazole (MMI). Propylthiouracil was given in the 1st trimester and Methimazole was given in 2nd and 3rd trimester. Results: There was statistically significant difference found between pretreatment and post treatment groups regarding Heat Intolerance, Palpitations, Tremors, and Irritability, while there was no statistically significant difference found between Pretreatment and Post treatment regarding Exophthalmos. Methimazole (MMI) is preferred to propyl-thiouracil (PTU) after the first trimester because PTU has an association with hepatotoxicity. However, PTU is recommended for the first trimester of pregnancy because its teratogenic effects are considered less severe than those of MMI. Conclusion: Management of hyperthyroidism during pregnancy and lactation requires special considerations and should be meticulously implemented to provide best care to pregnant woman and prevent any adverse effects. Thyrotoxicosis of pregnancy can present unique diagnostic challenges and, if untreated, is associated with increased risks of adverse maternal, fetal, and neonatal complications. The clinical presentation, serum thyroid function test results, and serum TRAb titers can help differentiate the etiology of thyrotoxicosis. However, assessment and monitoring with serum thyroid function tests can be difficult, as there is significant overlap between test results arising from normal pregnancy physiology and intrinsic hyperthyroidism.
背景:自身免疫性GD (Graves病)是育龄妇女甲状腺功能亢进的最常见原因。为预防母胎并发症,妊娠期甲状腺毒症应得到适当的管理和控制。与妊娠相关的生理适应对孕妇甲状腺功能的评估提出了挑战,抗甲状腺药物(ATD)的治疗引起了孕妇和胎儿的关注。本研究的目的是探讨甲状腺功能亢进对妊娠的影响,甲状腺功能亢进的不同诊断方法和妊娠期间甲状腺功能亢进的治疗方法,以获得良好的孕产妇健康和胎儿结局。目的:探讨甲亢对妊娠的影响及甲亢对妊娠的影响。探讨妊娠期甲状腺机能亢进的不同诊断方法。同时,研究妊娠期间甲状腺功能亢进和甲状腺毒症的治疗方法,以获得良好的孕产妇健康和胎儿结局。患者与方法:对2020年4月至2020年12月在巴布沙里亚大学和侯赛因大学附属医院就诊的20例不同妊娠阶段甲状腺毒症孕妇进行前瞻性随机临床研究。所选患者接受丙基硫脲嘧啶(PTU)和甲巯咪唑(MMI)两种主要药物中的一种。丙基硫脲嘧啶在妊娠早期给予,甲巯咪唑在妊娠中期和晚期给予。结果:治疗前后两组患者在不耐热、心悸、震颤、易怒方面差异有统计学意义,而在眼球突出方面,治疗前后两组差异无统计学意义。甲巯咪唑(MMI)优于丙基硫脲嘧啶(PTU),因为PTU与肝毒性有关。然而,PTU被推荐用于妊娠的前三个月,因为它的致畸作用被认为比MMI的致畸作用要轻。结论:妊娠期和哺乳期甲状腺功能亢进的处理需要特别注意,应精心实施,为孕妇提供最好的护理,防止任何不良反应。妊娠甲状腺毒症可以提出独特的诊断挑战,如果不治疗,与母体、胎儿和新生儿不良并发症的风险增加有关。临床表现、血清甲状腺功能检查结果和血清TRAb滴度有助于甲状腺毒症病因的鉴别。然而,血清甲状腺功能测试的评估和监测可能是困难的,因为正常妊娠生理和内在甲状腺功能亢进的测试结果之间存在显著的重叠。
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引用次数: 0
SURVEY OF INCIDENCE, INDICATIONS, COMPLICATIONS AND MANAGEMENT OF COMPLICATIONS OF CESAREAN SECTIONS AT EL-TAHRIR GENERAL HOSPITAL "IMBABA" DURING "2018-2019" 2018-2019年IMBABA EL-TAHRIR综合医院剖宫产的发生率、指征、并发症及并发症处理调查
Pub Date : 2022-07-01 DOI: 10.21608/amj.2022.245214
Mohammed E. M. Amar, Hossam A. Hussein, Osama M. Deif
Background: Cesarean section (CS) rates have been increasing worldwide, but little research exists on trends of cesarean section delivery for any country in the Arab world. Objectives: To present an updated assessment of incidence, indications, complications and management of complications of C.S about the patients at Al-Tahrir General Hospital (Imbaba) and making a statistical survey during (2018-2019) to reach to the most common indications and complications which if avoided, can improve the outcome for the mother and fetus. Patients and methods: This is a retrospective study, carried out at Obstetrics and Gynecology department at Al-Tahrir General Hospital, Faculty of Medicine, on one thousand and four hundred pregnant females, from August 2019 till December 2020. Result: There was a significant difference between previous CS and birth outcome as regards gestational age at birth. Among the studied cases regarding indications for caesarean section, 22.1% had previous cesarean deliveries, 17.7% had a late pregnancy, 18.5% had abnormal amniotic fluid, 4.2% had hypertensive disorder, and 11.2% labored Prolonged and obstructed, 14.6% had fetal problems, 7.14% had preeclampsia, 5.7% had preeclampsia, 4.3% had urinary tract infection, 7.9% had other problems. Among the cases studied according to the characteristics of the operation, the mean duration was 37.50 (±4.62) with a range (30-45), as for the level of surgeon, there were 20.9% consultant, 40.8% specialist, 38.4% resident, and for the estimates of blood loss there were 31.2% less From 1000, 65.8% between (1000-1500), 3% over 1500. Among the studied cases in terms of complications, there were 1.9% stillbirth, 1.8% infection complications, 0.3% breathing problems for the child, 1.9% surgical injury to the bladder, 1.1% severe bleeding, 0.1% fetal injury. Conclusion: Cesarean sections should be performed with caution. The main challenge related to cesarean sections is its best use which is an important resource for the reduction of maternal and neonatal mortality but on the other, when used excessively may be associated with an increased risk of serious maternal outcomes.
背景:剖宫产(CS)率在全球范围内一直在上升,但很少有研究表明阿拉伯世界任何国家的剖宫产趋势。目的:对Al Tahrir综合医院(Imbaba)患者的C.S发病率、适应症、并发症和并发症管理进行最新评估,并在2018年至2019年期间进行统计调查,以了解最常见的适应症和并发症,如果避免这些适应症和症候,可以改善母亲和胎儿的预后。患者和方法:这是一项回顾性研究,于2019年8月至2020年12月在Al Tahrir综合医院妇产科对1400名孕妇进行。结果:就出生时的胎龄而言,既往CS与出生结果之间存在显著差异。在关于剖腹产适应症的研究病例中,22.1%的患者曾进行过剖宫产,17.7%的患者妊娠晚期,18.5%的患者羊水异常,4.2%的患者患有高血压疾病,11.2%的患者长期分娩和分娩受阻,14.6%的患者有胎儿问题,7.14%的患者有先兆子痫,5.7%的患者存在先兆子痫,4.3%的患者有尿路感染,7.9%的患者还有其他问题。在根据手术特点研究的病例中,平均持续时间为37.50(±4.62),范围为(30-45)。就外科医生的水平而言,咨询师占20.9%,专科医生占40.8%,住院医生占38.4%,而对于失血量的估计,从1000开始减少31.2%,在(1000-1500)之间减少65.8%,在1500以上减少3%。在并发症方面的研究病例中,有1.9%的死产,1.8%的感染并发症,0.3%的儿童呼吸问题,1.9%的膀胱手术损伤,1.1%的严重出血,0.1%的胎儿损伤。结论:剖宫产手术应谨慎进行。剖宫产的主要挑战是其最佳使用,这是降低孕产妇和新生儿死亡率的重要资源,但另一方面,过度使用可能会增加严重产妇结局的风险。
{"title":"SURVEY OF INCIDENCE, INDICATIONS, COMPLICATIONS AND MANAGEMENT OF COMPLICATIONS OF CESAREAN SECTIONS AT EL-TAHRIR GENERAL HOSPITAL \"IMBABA\" DURING \"2018-2019\"","authors":"Mohammed E. M. Amar, Hossam A. Hussein, Osama M. Deif","doi":"10.21608/amj.2022.245214","DOIUrl":"https://doi.org/10.21608/amj.2022.245214","url":null,"abstract":"Background: Cesarean section (CS) rates have been increasing worldwide, but little research exists on trends of cesarean section delivery for any country in the Arab world. Objectives: To present an updated assessment of incidence, indications, complications and management of complications of C.S about the patients at Al-Tahrir General Hospital (Imbaba) and making a statistical survey during (2018-2019) to reach to the most common indications and complications which if avoided, can improve the outcome for the mother and fetus. Patients and methods: This is a retrospective study, carried out at Obstetrics and Gynecology department at Al-Tahrir General Hospital, Faculty of Medicine, on one thousand and four hundred pregnant females, from August 2019 till December 2020. Result: There was a significant difference between previous CS and birth outcome as regards gestational age at birth. Among the studied cases regarding indications for caesarean section, 22.1% had previous cesarean deliveries, 17.7% had a late pregnancy, 18.5% had abnormal amniotic fluid, 4.2% had hypertensive disorder, and 11.2% labored Prolonged and obstructed, 14.6% had fetal problems, 7.14% had preeclampsia, 5.7% had preeclampsia, 4.3% had urinary tract infection, 7.9% had other problems. Among the cases studied according to the characteristics of the operation, the mean duration was 37.50 (±4.62) with a range (30-45), as for the level of surgeon, there were 20.9% consultant, 40.8% specialist, 38.4% resident, and for the estimates of blood loss there were 31.2% less From 1000, 65.8% between (1000-1500), 3% over 1500. Among the studied cases in terms of complications, there were 1.9% stillbirth, 1.8% infection complications, 0.3% breathing problems for the child, 1.9% surgical injury to the bladder, 1.1% severe bleeding, 0.1% fetal injury. Conclusion: Cesarean sections should be performed with caution. The main challenge related to cesarean sections is its best use which is an important resource for the reduction of maternal and neonatal mortality but on the other, when used excessively may be associated with an increased risk of serious maternal outcomes.","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46392035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STUDY THE THERAPEUTIC ROLE OF BILATERAL TRANSCRANIAL MAGNETIC STIMULATION IN A SAMPLE OF PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER ATTENDING AL-AZHAR UNIVERSITY HOSPITALS 研究双侧经颅磁刺激在爱资哈尔大学附属医院强迫症患者中的治疗作用
Pub Date : 2022-07-01 DOI: 10.21608/amj.2022.240778
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引用次数: 0
EVALUATION OF LOCAL AXIAL FLAPS IN SCALP DEFECTS RECONSTRUCTION 局部轴向皮瓣在头皮缺损重建中的应用价值
Pub Date : 2022-07-01 DOI: 10.21608/amj.2022.240673
Background: The scalp consists of specialized tissue composed of dense hair follicles and inelastic thick galea aponeurotica, unlike other tissues of the body. Reconstruction of the scalp can be challenging because of the convexity of the underlying skeleton, the inelasticity of the galea, and the paucity of the adjacent tissue, which make even small defects difficult to close. Objective: To evaluate the local axial flaps used in reconstruction of the different scalp defects in terms of feeding vessels, arc of rotation, and flap dimensions. Patients and Methods: Twenty patients between 5-68 years old who had medium to huge scalp defects caused by burn, trauma and malignancy were subjected to this study at Al-Azhar University Hospitals (Al-Hussein and Al-Sayed Galal) to evaluate the effect of local axial flaps in them in terms of stable coverage of the defects with similar hair-bearing tissue, re-creation of the hairline, matching skin thickness, color and minimal donor site morbidity. Results: Non-expanded rotational and expanded advancement flap were the most used flaps, and the least used was the transposition flap. Minor complications included: seroma happened in 3 patients (25.0%) and graft loss in 2 patients (10%). Distal flap necrosis occurred in 3 patients (15%), TE Exposure in 2 patients (10%), wound dehiscence in 2 patients (10%), and ischemic necrosis of skin over the expander happened in 1 patient (5%). Conclusion: Reconstruction of scalp defects with local flaps is a safe, relatively short and simple procedure unlikely to cause any major complications or demand special postoperative care. In cranial or dural defect, a local scalp flap is the reconstructive method of choice. Application of local axial flaps indicates that complications were quite rare and did not extensively affect the survival of the flaps.
{"title":"EVALUATION OF LOCAL AXIAL FLAPS IN SCALP DEFECTS RECONSTRUCTION","authors":"","doi":"10.21608/amj.2022.240673","DOIUrl":"https://doi.org/10.21608/amj.2022.240673","url":null,"abstract":"Background: The scalp consists of specialized tissue composed of dense hair follicles and inelastic thick galea aponeurotica, unlike other tissues of the body. Reconstruction of the scalp can be challenging because of the convexity of the underlying skeleton, the inelasticity of the galea, and the paucity of the adjacent tissue, which make even small defects difficult to close. Objective: To evaluate the local axial flaps used in reconstruction of the different scalp defects in terms of feeding vessels, arc of rotation, and flap dimensions. Patients and Methods: Twenty patients between 5-68 years old who had medium to huge scalp defects caused by burn, trauma and malignancy were subjected to this study at Al-Azhar University Hospitals (Al-Hussein and Al-Sayed Galal) to evaluate the effect of local axial flaps in them in terms of stable coverage of the defects with similar hair-bearing tissue, re-creation of the hairline, matching skin thickness, color and minimal donor site morbidity. Results: Non-expanded rotational and expanded advancement flap were the most used flaps, and the least used was the transposition flap. Minor complications included: seroma happened in 3 patients (25.0%) and graft loss in 2 patients (10%). Distal flap necrosis occurred in 3 patients (15%), TE Exposure in 2 patients (10%), wound dehiscence in 2 patients (10%), and ischemic necrosis of skin over the expander happened in 1 patient (5%). Conclusion: Reconstruction of scalp defects with local flaps is a safe, relatively short and simple procedure unlikely to cause any major complications or demand special postoperative care. In cranial or dural defect, a local scalp flap is the reconstructive method of choice. Application of local axial flaps indicates that complications were quite rare and did not extensively affect the survival of the flaps.","PeriodicalId":84126,"journal":{"name":"Al Azhar medical journal = Majallat al-Tibb al-Azhar","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42212589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Al Azhar medical journal = Majallat al-Tibb al-Azhar
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