Pub Date : 2015-09-29DOI: 10.1186/s40733-015-0011-5
R. Normansell, E. Welsh
{"title":"“Asthma can take over your life but having the right support makes that easier to deal with.” Informing research priorities by exploring the barriers and facilitators to asthma control: a qualitative analysis of survey data","authors":"R. Normansell, E. Welsh","doi":"10.1186/s40733-015-0011-5","DOIUrl":"https://doi.org/10.1186/s40733-015-0011-5","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0011-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65749326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-22eCollection Date: 2015-01-01DOI: 10.1186/s40733-015-0009-z
Neha M Dunn, Rohit K Katial, Flavia C L Hoyte
Vocal cord dysfunction (VCD) is a term that refers to inappropriate adduction of the vocal cords during inhalation and sometimes exhalation. It is a functional disorder that serves as an important mimicker of asthma. Vocal cord dysfunction can be difficult to treat as the condition is often underappreciated and misdiagnosed in clinical practice. Recognition of vocal cord dysfunction in patients with asthma-type symptoms is essential since missing this diagnosis can be a barrier to adequately treating patients with uncontrolled respiratory symptoms. Although symptoms often mimic asthma, the two conditions have certain distinct clinical features and demonstrate specific findings on diagnostic studies, which can serve to differentiate the two conditions. Moreover, management of vocal cord dysfunction should be directed at minimizing known triggers and initiating speech therapy, thereby minimizing use of unnecessary asthma medications. This review article describes key clinical features, important physical exam findings and commonly reported triggers in patients with vocal cord dysfunction. Additionally, this article discusses useful diagnostic studies to identify patients with vocal cord dysfunction and current management options for such patients.
{"title":"Vocal cord dysfunction: a review.","authors":"Neha M Dunn, Rohit K Katial, Flavia C L Hoyte","doi":"10.1186/s40733-015-0009-z","DOIUrl":"10.1186/s40733-015-0009-z","url":null,"abstract":"<p><p>Vocal cord dysfunction (VCD) is a term that refers to inappropriate adduction of the vocal cords during inhalation and sometimes exhalation. It is a functional disorder that serves as an important mimicker of asthma. Vocal cord dysfunction can be difficult to treat as the condition is often underappreciated and misdiagnosed in clinical practice. Recognition of vocal cord dysfunction in patients with asthma-type symptoms is essential since missing this diagnosis can be a barrier to adequately treating patients with uncontrolled respiratory symptoms. Although symptoms often mimic asthma, the two conditions have certain distinct clinical features and demonstrate specific findings on diagnostic studies, which can serve to differentiate the two conditions. Moreover, management of vocal cord dysfunction should be directed at minimizing known triggers and initiating speech therapy, thereby minimizing use of unnecessary asthma medications. This review article describes key clinical features, important physical exam findings and commonly reported triggers in patients with vocal cord dysfunction. Additionally, this article discusses useful diagnostic studies to identify patients with vocal cord dysfunction and current management options for such patients.</p>","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-07DOI: 10.1186/s40733-015-0008-0
M. Egan, S. Bunyavanich
{"title":"Allergic rhinitis: the “Ghost Diagnosis” in patients with asthma","authors":"M. Egan, S. Bunyavanich","doi":"10.1186/s40733-015-0008-0","DOIUrl":"https://doi.org/10.1186/s40733-015-0008-0","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0008-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-08-05DOI: 10.1186/s40733-015-0007-1
I. Baiardini, Francesca Sicuro, F. Balbi, G. Canonica, F. Braido
{"title":"Psychological aspects in asthma: do psychological factors affect asthma management?","authors":"I. Baiardini, Francesca Sicuro, F. Balbi, G. Canonica, F. Braido","doi":"10.1186/s40733-015-0007-1","DOIUrl":"https://doi.org/10.1186/s40733-015-0007-1","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0007-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-15eCollection Date: 2015-01-01DOI: 10.1186/s40733-015-0006-2
Giovanni Passalacqua, Anthi Rogkakou, Marcello Mincarini, Giorgio Walter Canonica
The use and role of allergen immunotherapy (AIT) in asthma is still a matter of debate, and no definite recommendation about this is made in guidelines, both for the subcutaneous and sublingual routes. This is essentially due to the fact that most controlled randomised trials were not specifically designed for asthma, and that objective measures of pulmonary function were only occasionally considered. Nonetheless, in many trials, favourable results in asthma (symptoms, medication usage, bronchial reactivity) were consistently reported. There are also several meta analyses in favour of AIT, although their validity is limited by a relevant methodological heterogeneity. In addition to the crude clinical effect, a disease modifying action of AIT (prevention of asthma onset and long-lasting effects) have been reported. The safety is an important aspect to consider in asthma. Fatalities were rare: in Europe no fatality was reported in the last three decades, as in the United States in the last 4 years. Based on previous surveys, and common sense, uncontrolled asthma is still recognized as the most important risk factor for severe adverse events. On the contrary, there is no evidence that AIT can worsen or induce asthma. According to the available evidence, AIT can be safely used as add-on treatment when asthma is associated with rhinitis (a frequent condition), provided that asthma is adequately controlled by pharmacotherapy. AIT cannot be recommended or suggested as single therapy. When asthma is the unique manifestation of respiratory allergy, its use should be evaluated case by case.
过敏原免疫疗法（AIT）在哮喘中的应用和作用仍是一个争论不休的问题，无论是皮下途径还是舌下途径，指南中都没有对此提出明确的建议。这主要是由于大多数随机对照试验并不是专门针对哮喘设计的，而且只是偶尔考虑对肺功能进行客观测量。尽管如此，在许多试验中，对哮喘（症状、用药情况、支气管反应性）的治疗效果都很好。此外，还有几项荟萃分析支持 AIT，但其有效性受到相关方法异质性的限制。除了粗略的临床效果外，也有报道称 AIT 还具有改变疾病的作用（预防哮喘发作并具有长期效果）。安全性是哮喘治疗中需要考虑的一个重要方面。死亡病例非常罕见：欧洲在过去三十年中没有死亡病例的报道，美国在过去四年中也是如此。根据以往的调查和常识，不受控制的哮喘仍被认为是导致严重不良事件的最重要风险因素。相反，没有证据表明 AIT 会加重或诱发哮喘。根据现有证据，如果哮喘伴有鼻炎（一种常见病），且药物治疗已充分控制哮喘，则可以安全地将 AIT 用作附加治疗。不能推荐或建议将 AIT 作为单一疗法。当哮喘是呼吸道过敏的独特表现时，应根据具体病例对其使用进行评估。
{"title":"Allergen immunotherapy in asthma; what is new?","authors":"Giovanni Passalacqua, Anthi Rogkakou, Marcello Mincarini, Giorgio Walter Canonica","doi":"10.1186/s40733-015-0006-2","DOIUrl":"10.1186/s40733-015-0006-2","url":null,"abstract":"<p><p>The use and role of allergen immunotherapy (AIT) in asthma is still a matter of debate, and no definite recommendation about this is made in guidelines, both for the subcutaneous and sublingual routes. This is essentially due to the fact that most controlled randomised trials were not specifically designed for asthma, and that objective measures of pulmonary function were only occasionally considered. Nonetheless, in many trials, favourable results in asthma (symptoms, medication usage, bronchial reactivity) were consistently reported. There are also several meta analyses in favour of AIT, although their validity is limited by a relevant methodological heterogeneity. In addition to the crude clinical effect, a disease modifying action of AIT (prevention of asthma onset and long-lasting effects) have been reported. The safety is an important aspect to consider in asthma. Fatalities were rare: in Europe no fatality was reported in the last three decades, as in the United States in the last 4 years. Based on previous surveys, and common sense, uncontrolled asthma is still recognized as the most important risk factor for severe adverse events. On the contrary, there is no evidence that AIT can worsen or induce asthma. According to the available evidence, AIT can be safely used as add-on treatment when asthma is associated with rhinitis (a frequent condition), provided that asthma is adequately controlled by pharmacotherapy. AIT cannot be recommended or suggested as single therapy. When asthma is the unique manifestation of respiratory allergy, its use should be evaluated case by case.</p>","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-07-02DOI: 10.1186/s40733-015-0004-4
M. Bonini, P. Palange
{"title":"Exercise-induced bronchoconstriction: new evidence in pathogenesis, diagnosis and treatment","authors":"M. Bonini, P. Palange","doi":"10.1186/s40733-015-0004-4","DOIUrl":"https://doi.org/10.1186/s40733-015-0004-4","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0004-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-06-04DOI: 10.1186/s40733-015-0001-7
C. Baffi, D. Winnica, F. Holguin
{"title":"Asthma and obesity: mechanisms and clinical implications","authors":"C. Baffi, D. Winnica, F. Holguin","doi":"10.1186/s40733-015-0001-7","DOIUrl":"https://doi.org/10.1186/s40733-015-0001-7","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0001-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-06-04DOI: 10.1186/s40733-015-0005-3
J. Celedón, G. Passalacqua, G. Canonica
{"title":"Asthma research and practice: a new journey begins","authors":"J. Celedón, G. Passalacqua, G. Canonica","doi":"10.1186/s40733-015-0005-3","DOIUrl":"https://doi.org/10.1186/s40733-015-0005-3","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0005-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-06-04DOI: 10.1186/s40733-015-0002-6
C. Lombardi, Eleonora Musicco, F. Rastrelli, G. Bettoncelli, G. Passalacqua, G. Canonica
{"title":"The patient with rhinitis in the pharmacy. A cross-sectional study in real life","authors":"C. Lombardi, Eleonora Musicco, F. Rastrelli, G. Bettoncelli, G. Passalacqua, G. Canonica","doi":"10.1186/s40733-015-0002-6","DOIUrl":"https://doi.org/10.1186/s40733-015-0002-6","url":null,"abstract":"","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s40733-015-0002-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65748986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-01-01Epub Date: 2015-10-08DOI: 10.1186/s40733-015-0010-6
Marissa Hauptman, Wanda Phipatanakul
In this article, we discuss the relationship between environmental exposures within the school environment and pediatric asthma morbidity. This article will conclude by reviewing novel school based asthma education and therapeutic programs and environmental interventions designed to help mitigate pediatric asthma morbidity.
{"title":"The school environment and asthma in childhood.","authors":"Marissa Hauptman, Wanda Phipatanakul","doi":"10.1186/s40733-015-0010-6","DOIUrl":"10.1186/s40733-015-0010-6","url":null,"abstract":"<p><p>In this article, we discuss the relationship between environmental exposures within the school environment and pediatric asthma morbidity. This article will conclude by reviewing novel school based asthma education and therapeutic programs and environmental interventions designed to help mitigate pediatric asthma morbidity.</p>","PeriodicalId":8572,"journal":{"name":"Asthma research and practice","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9931662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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