Australian and New Zealand journal of ophthalmology最新文献

Purpose: To describe the ocular anomalies in two cases of branchio-oculo-facial syndrome (BOFS).

Methods: Two cases of BOFS are reviewed.

Results/conclusions: Branchio-oculo-facial syndrome is a rare branchial cleft syndrome that is characterized by a typical facial appearance of pseudo-cleft or cleft lip, subauricular branchial sinuses, deafness and ocular anomalies, which include nasolacrimal obstruction, telecanthus and colobomata. It has an autosomal dominant inheritance pattern.

Because different electrophysiological responses can be isolated to different retinal and cortical cell types and levels, the proportion in which the different signals are reduced can reflect the primary areas of damage. The knowledge of electrophysiology component sources can thus be applied when examining ophthalmic disorders. The present review covers the proposed origins and the usefulness of the conventional electrophysiological responses. Their application to glaucoma is discussed, with particular reference to the pattern electroretinogram. In the second part of the current review, we present some recent developments that relate to the use of multifocal pseudorandomly stimulated recording. This technique enables a new approach to the electrical assessment of visual responses. Analysis for temporal non-linearities and spatial distribution of the response throughout the visual field can be implemented. This type of recording has the potential to provide a method of objective visual field assessment in glaucoma and other disorders of the visual system.

Purpose/method: A case of a 28-year-old Maori with an aggressive primary choroidal malignant melanoma is presented.

Results/conclusion: Melanoma and particularly intra-ocular melanoma is very rare in pigmented races. This is the first reported case in the Maori.

Purpose: Unoperated cataract is the leading cause of blindness in the developing world. Many developing countries now use extracapsular cataract extraction (ECCE) with intra-ocular lens insertion (IOL) in their cataract blindness-prevention programmes. To date, little research has been directed at visual outcomes and complication rates of ECCE/IOL surgery in developing countries.

Methods: We conducted a follow-up study of 155 eyes approximately 12 months after ECCE/IOL surgery by eight local eye surgeons in Central Vietnam. We report the findings for the 144 eyes (93%) successfully reviewed. All subjects underwent manual ECCE with insertion of a three-piece posterior chamber IOL. All eyes were also assessed for the presence and severity of posterior capsule opacification (PCO) using a newly developed grading system.

Results: Overall, 110 eyes (75%) had uncorrected visual acuities > or = 6/24 and 107 eyes (74%) had best spherically corrected visual acuities > or = 6/18. Some degree of PCO was found in 40% of eyes, but was graded as visually significant in only 4% of eyes. No major sight-threatening complications were noted. A portable neodymium:yttrium aluminium garnet (Nd:YAG) laser was used to perform capsulotomies on all eyes with visually significant PCO. There were no laser complications noted.

Conclusions: At approximately 1 year after ECCE/IOL, the visual outcomes for subjects in this cohort were favourable and complication rates were low. Posterior chamber opacification was not a major cause of vision impairment in this cohort. Portable Nd:YAG lasers may provide an effective solution to the problem of visually significant PCO occurring in developing countries as a late complication of extracapsular surgery. These findings support an increasing role for ECCE/PCIOL surgery by trained local eye surgeons in developing countries.