{"title":"The influence of some hormonal, dietary, and tumor factors on liver catalase activity in rats.","authors":"R W BEGG, T E DICKINSON, A V WHITE","doi":"10.1139/cjms53-031","DOIUrl":"https://doi.org/10.1139/cjms53-031","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 4","pages":"307-14"},"PeriodicalIF":0.0,"publicationDate":"1953-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22680700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatty livers were produced in guinea pigs by the repeated feeding or injection of ethionine; the acinar cells of the pancreas were also affected in some of the animals. Marked changes in plasma coagulability always occurred as well as a definite reduction in complement titer in which two or more of the major complement components were involved. Methionine displayed some protective effect against the fatty liver induced by the ethionine and was partially effective in controlling the coagulative changes and the decline in complement titer. In some animals, choline likewise ameliorated these conditions, whereas cystine tended to aggravate them. A combination of cystine and choline was more effective than choline alone.
{"title":"Parallel studies of complement and blood coagulation. IX. The effect of methionine, choline, and cystine on the changes induced by ethionine.","authors":"C E RICE, P BOULANGER, P J PLUMMER, E ANNAU","doi":"10.1139/cjms53-036","DOIUrl":"https://doi.org/10.1139/cjms53-036","url":null,"abstract":"Fatty livers were produced in guinea pigs by the repeated feeding or injection of ethionine; the acinar cells of the pancreas were also affected in some of the animals. Marked changes in plasma coagulability always occurred as well as a definite reduction in complement titer in which two or more of the major complement components were involved. Methionine displayed some protective effect against the fatty liver induced by the ethionine and was partially effective in controlling the coagulative changes and the decline in complement titer. In some animals, choline likewise ameliorated these conditions, whereas cystine tended to aggravate them. A combination of cystine and choline was more effective than choline alone.","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 4","pages":"343-57"},"PeriodicalIF":0.0,"publicationDate":"1953-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22680705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of benign and malignant tumors on liver catalase activity.","authors":"R W BEGG, T E DICKINSON, J MILLAR","doi":"10.1139/cjms53-032","DOIUrl":"https://doi.org/10.1139/cjms53-032","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 4","pages":"315-9"},"PeriodicalIF":0.0,"publicationDate":"1953-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-032","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22680701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cholera vaccine prepared in a chemically defined fluid medium (containing tyrosine, asparagine, glycine, and inorganic salts) was compared antigenically in mice with vaccines prepared by standard methods. The mean LD50 for normal mice was 108 ± 9.1 V. comma of the strain employed for challenging. Both vaccines afforded a high degree of protection. Mice immunized with bivalent (Ogawa and Inaba) Standard vaccine had a mean LD50 of 40.0 ± 4.7 million V. comma. Mice protected by bivalent fluid-prepared vaccine had a mean LD50 of 32.7 ± 6.0 million V. comma. The difference is not statistically significant. Vaccines prepared in fluid medium were relatively unstable.
{"title":"The antigenicity of cholera vaccine prepared in fluid medium.","authors":"L E RANTA, P M MCCREERY","doi":"10.1139/cjms53-035","DOIUrl":"https://doi.org/10.1139/cjms53-035","url":null,"abstract":"Cholera vaccine prepared in a chemically defined fluid medium (containing tyrosine, asparagine, glycine, and inorganic salts) was compared antigenically in mice with vaccines prepared by standard methods. The mean LD50 for normal mice was 108 ± 9.1 V. comma of the strain employed for challenging. Both vaccines afforded a high degree of protection. Mice immunized with bivalent (Ogawa and Inaba) Standard vaccine had a mean LD50 of 40.0 ± 4.7 million V. comma. Mice protected by bivalent fluid-prepared vaccine had a mean LD50 of 32.7 ± 6.0 million V. comma. The difference is not statistically significant. Vaccines prepared in fluid medium were relatively unstable.","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 4","pages":"338-42"},"PeriodicalIF":0.0,"publicationDate":"1953-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22680704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Three strains of poliomyelitis virus isolated from Eskimos infected in the outbreak of poliomyelitis occurring at Chesterfield Inlet, N.W.T., in February 1949 have been typed. This typing has been ...
{"title":"Poliomyelitis in Canadian Eskimos laboratory studies. IV. Antigenic typing of virus strains in monkeys and in tissue cultures.","authors":"W WOOD, E M CLARK, F T SHIMADA, A J RHODES","doi":"10.1139/cjms53-023","DOIUrl":"https://doi.org/10.1139/cjms53-023","url":null,"abstract":"Three strains of poliomyelitis virus isolated from Eskimos infected in the outbreak of poliomyelitis occurring at Chesterfield Inlet, N.W.T., in February 1949 have been typed. This typing has been ...","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 3","pages":"207-21"},"PeriodicalIF":0.0,"publicationDate":"1953-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22659983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The absorption of light, in the visible and ultraviolet, by certain steroids in sulphuric acid and ethanol solutions.","authors":"J H LINFORD, O J FLEMING","doi":"10.1139/cjms53-020","DOIUrl":"https://doi.org/10.1139/cjms53-020","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 3","pages":"182-94"},"PeriodicalIF":0.0,"publicationDate":"1953-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22659980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ROUND TABLE DISCUSSION HELD IN EVENING","authors":"O. F. Denstedt","doi":"10.1139/CJMS53-030","DOIUrl":"https://doi.org/10.1139/CJMS53-030","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"103 1","pages":"302-305"},"PeriodicalIF":0.0,"publicationDate":"1953-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/CJMS53-030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64114119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The metabolism of C14-urea in the rat.","authors":"S H ZBARSKY, W D WRIGHT","doi":"10.1139/cjms53-017","DOIUrl":"https://doi.org/10.1139/cjms53-017","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 3","pages":"151-61"},"PeriodicalIF":0.0,"publicationDate":"1953-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-017","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22663172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of phenylindanedione and dicumarol in experimental frostbite.","authors":"E LEPP, W CHUBATY, L B JACQUES","doi":"10.1139/cjms53-019","DOIUrl":"https://doi.org/10.1139/cjms53-019","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 3","pages":"173-81"},"PeriodicalIF":0.0,"publicationDate":"1953-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22659979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pressure as a possible cause of dissolution and redeposition of bone and tooth crystals.","authors":"R E GLEGG, C P LEBLOND","doi":"10.1139/cjms53-022","DOIUrl":"https://doi.org/10.1139/cjms53-022","url":null,"abstract":"","PeriodicalId":86015,"journal":{"name":"Canadian journal of medical sciences","volume":"31 3","pages":"202-6"},"PeriodicalIF":0.0,"publicationDate":"1953-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1139/cjms53-022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22659982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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