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GINKGO, GINKGO BILOBA 银杏
Pub Date : 2022-02-01 DOI: 10.2307/j.ctv21hrk34.45
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引用次数: 0
Evaluation of the hepatic metabolism and antitumor activity of noni juice (Morinda citrifolia L.) in combination with chemotherapy 诺丽果汁联合化疗对肝脏代谢和抗肿瘤活性的影响
Pub Date : 2010-06-01 DOI: 10.2310/7200.2010.0008
K. Santiago, A. Gaikwad, L. Coffer, Judith A. Smith
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引用次数: 7
Yoga for Pain and Anxiety in Pediatric Hematology- Oncology Patients: Case Series and Review of the Literature 瑜伽治疗儿童血液学-肿瘤患者的疼痛和焦虑:病例系列和文献回顾
Pub Date : 2010-06-01 DOI: 10.2310/7200.2010.0005
K. Moody, Dina Daswani, B. Abrahams, R. Santizo
In response to rising interests from patients, many comprehensive cancer centers now offer an integrative model of care which includes the provision of complementary medicine. Yoga is one such intervention that has been used in children. We performed an Institutional Review Board (IRB) approved chart review of pediatric hematology-oncology patients who received yoga. Patients with sickle cell vaso-occlusive pain crises or cancer were offered bedside yoga by a certifi ed yoga instructor. Pain before and after yoga was reported using the 10-point Wong-Baker FACES pain scale. Anxiety before and after yoga was assessed with the State-Trait Anxiety Inventory. Qualitative patient quotes were extracted from the yoga therapist’s notes. Twenty patient’s charts were reviewed, 50% were male. The mean age was 18 years, (range 11–26 years.) Most common diagnoses were sickle cell vaso-occlusive pain crises (45%), and sarcoma (40%.) The mean reduction in pain score was 0.94 (SD ± 1.68), p = .005, and the mean reduction in anxiety T-score was 9.62 (SD ± 6.74), p = .0001. Patient quotes suggest that yoga was benefi cial, especially for relaxation. Literature review offers preliminary support for the use of yoga for anxiety in children. Our data suggest that further research on yoga as an effective intervention for pediatric hematology-oncology patients for pain and anxiety is needed.
为了回应患者日益增长的兴趣,许多综合性癌症中心现在提供包括提供补充医学在内的综合护理模式。瑜伽就是其中一种已经在儿童身上使用的干预方法。我们对接受瑜伽治疗的儿科血液肿瘤患者进行了机构审查委员会(IRB)批准的图表审查。镰状细胞血管闭塞性疼痛危像或癌症患者由认证瑜伽教练提供床边瑜伽。采用10分制Wong-Baker FACES疼痛量表报告瑜伽前后的疼痛。用状态-特质焦虑量表评估瑜伽前后的焦虑程度。定性的病人语录是从瑜伽治疗师的笔记中提取出来的。回顾了20例患者的病历,其中50%为男性。平均年龄18岁(范围11-26岁)。最常见的诊断是镰状细胞性血管闭塞性疼痛危象(45%)和肉瘤(40%)。疼痛评分平均降低0.94 (SD±1.68),p = 0.005;焦虑t评分平均降低9.62 (SD±6.74),p = 0.0001。病人说,瑜伽是有益的,尤其是放松。文献综述为使用瑜伽治疗儿童焦虑提供了初步支持。我们的数据表明,需要进一步研究瑜伽作为儿童血液肿瘤患者疼痛和焦虑的有效干预措施。
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引用次数: 8
Phase II Randomized Trial of Acupuncture-Like Transcutaneous Electrical Nerve Stimulation to Prevent Radiation-Induced Xerostomia in Head and Neck Cancer Patients. 针刺样经皮神经电刺激预防头颈癌患者放射性口干的II期随机试验。
Raimond K Wong, Stephen M Sagar, Bao J Chen, Grace Y Yi, Richard Cook

Current evidence indicates that acupuncture-like transcutaneous electrical nerve stimulation (ALTENS) can provide sustained benefit for established radiation-induced xerostomia (RIX) symptoms. This is further being evaluated by comparing it with standard treatment (pilocarpine) in a randomized controlled trial. This report studies the potential effectiveness of xerostomia prevention using ALTENS delivered concomitantly with radiotherapy administered to head and neck cancer patients. Sixty patients were randomized to either the treatment group (n = 30) that received ALTENS daily with radiotherapy or the control group (n = 26) that had standard mouth care only. Stimulated and basal unstimulated whole saliva production (WSP) plus RIX symptoms visual analogue score (RIXVAS) were assessed at specific time points. Generalized linear models and generalized estimating equations were used for analysis. RIXVAS at 3 months follow-up after therapy completion was used as the primary study endpoint. The mean RIXVAS for the ALTENS intervention at 3 months was 39.8, which was not significantly different from the control arm value of 40.5. There were no statistically significant differences between the two groups for their mean RIXVAS and WSP at all assessment time points. In conclusion, there was no significant difference in mean WSP and RIXVAS between the two groups, so ALTENS is not recommended as a prophylactic intervention.

目前的证据表明,针刺样经皮神经电刺激(ALTENS)可以为已确定的辐射性口干(RIX)症状提供持续的益处。在一项随机对照试验中,通过将其与标准治疗(匹罗卡品)进行比较,进一步对其进行评估。本报告研究了使用ALTENS联合放疗预防头颈癌患者口干症的潜在有效性。60例患者被随机分为治疗组(n = 30)和对照组(n = 26),治疗组每天接受ALTENS和放疗,对照组只接受标准口腔护理。在特定时间点评估刺激和基础非刺激全唾液生成(WSP)加上RIX症状视觉模拟评分(RIXVAS)。采用广义线性模型和广义估计方程进行分析。治疗结束后随访3个月的RIXVAS作为主要研究终点。ALTENS干预3个月时的平均RIXVAS为39.8,与对照组的40.5无显著差异。两组在所有评估时间点的平均RIXVAS和WSP均无统计学差异。综上所述,两组患者的平均WSP和RIXVAS无显著差异,因此不建议将ALTENS作为预防性干预措施。
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引用次数: 0
Phase II Randomized Trial of Acupuncture-Like Transcutaneous Electrical Nerve Stimulation to Prevent Radiation-Induced Xerostomia in Head and Neck Cancer Patients. 针刺样经皮神经电刺激预防头颈癌患者放射性口干的II期随机试验。
Pub Date : 2010-01-01 DOI: 10.2310/7200.2009.0022
R. Wong, S. Sagar, Bao-jun Chen, G. Yi, R. Cook
Current evidence indicates that acupuncture-like transcutaneous electrical nerve stimulation (ALTENS) can provide sustained benefit for established radiation-induced xerostomia (RIX) symptoms. This is further being evaluated by comparing it with standard treatment (pilocarpine) in a randomized controlled trial. This report studies the potential effectiveness of xerostomia prevention using ALTENS delivered concomitantly with radiotherapy administered to head and neck cancer patients. Sixty patients were randomized to either the treatment group (n = 30) that received ALTENS daily with radiotherapy or the control group (n = 26) that had standard mouth care only. Stimulated and basal unstimulated whole saliva production (WSP) plus RIX symptoms visual analogue score (RIXVAS) were assessed at specific time points. Generalized linear models and generalized estimating equations were used for analysis. RIXVAS at 3 months follow-up after therapy completion was used as the primary study endpoint. The mean RIXVAS for the ALTENS intervention at 3 months was 39.8, which was not significantly different from the control arm value of 40.5. There were no statistically significant differences between the two groups for their mean RIXVAS and WSP at all assessment time points. In conclusion, there was no significant difference in mean WSP and RIXVAS between the two groups, so ALTENS is not recommended as a prophylactic intervention.
目前的证据表明,针刺样经皮神经电刺激(ALTENS)可以为已确定的辐射性口干(RIX)症状提供持续的益处。在一项随机对照试验中,通过将其与标准治疗(匹罗卡品)进行比较,进一步对其进行评估。本报告研究了使用ALTENS联合放疗预防头颈癌患者口干症的潜在有效性。60例患者被随机分为治疗组(n = 30)和对照组(n = 26),治疗组每天接受ALTENS和放疗,对照组只接受标准口腔护理。在特定时间点评估刺激和基础非刺激全唾液生成(WSP)加上RIX症状视觉模拟评分(RIXVAS)。采用广义线性模型和广义估计方程进行分析。治疗结束后随访3个月的RIXVAS作为主要研究终点。ALTENS干预3个月时的平均RIXVAS为39.8,与对照组的40.5无显著差异。两组在所有评估时间点的平均RIXVAS和WSP均无统计学差异。综上所述,两组患者的平均WSP和RIXVAS无显著差异,因此不建议将ALTENS作为预防性干预措施。
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引用次数: 12
Yoga improves quality of life and benefit finding in women undergoing radiotherapy for breast cancer. 瑜伽提高生活质量,对接受乳腺癌放疗的妇女有益。
Pub Date : 2010-01-01 DOI: 10.2310/7200.2010.0002
K. Chandwani, B. Thornton, G. Perkins, B. Arun, N. Raghuram, H. Nagendra, Q. Wei, L. Cohen
This study examined the effects of yoga on quality of life (QOL) and psychosocial outcomes in women with breast cancer undergoing radiotherapy. Sixty-one women were randomly assigned to either a yoga or a wait-list group. Yoga classes were taught biweekly during the 6 weeks of radiotherapy. Participants completed measures of QOL, fatigue, benefit finding (finding meaning in the cancer experience), intrusive thoughts, sleep disturbances, depressive symptoms, and anxiety before radiotherapy and then again 1 week, 1 month, and 3 months after the end of radiotherapy. General linear model analyses revealed that compared to the control group, the yoga group reported significantly better general health perception (p = .005) and physical functioning scores (p = .04) 1 week postradiotherapy; higher levels of intrusive thoughts 1 month postradiotherapy (p = .01); and greater benefit finding 3 months postradiotherapy (p = .01). There were no other group differences in other QOL subscales for fatigue, depression, or sleep scores. Exploratory analyses indicated that intrusive thoughts 1 month after radiotherapy were significantly positively correlated with benefit finding 3 months after radiotherapy (r = .36, p = .011). Our results indicated that the yoga program was associated with statistically and clinically significant improvements in aspects of QOL.
这项研究考察了瑜伽对接受放疗的乳腺癌患者的生活质量(QOL)和心理社会结果的影响。61名女性被随机分配到瑜伽组和等候组。在6周的放射治疗期间,每两周进行一次瑜伽课程。参与者在放疗前、放疗结束后1周、1个月和3个月分别完成了生活质量、疲劳、寻找益处(在癌症经历中寻找意义)、侵入性思维、睡眠障碍、抑郁症状和焦虑的测量。一般线性模型分析显示,与对照组相比,瑜伽组在治疗后1周报告了更好的总体健康感知(p = 0.005)和身体功能评分(p = 0.04);治疗后1个月侵入性思维水平升高(p = 0.01);放疗后3个月获益更大(p = 0.01)。在疲劳、抑郁或睡眠评分的其他生活质量亚量表上没有其他组间差异。探索性分析表明,放疗后1个月的侵入性思维与放疗后3个月的获益感显著正相关(r = 0.36, p = 0.011)。我们的研究结果表明,瑜伽项目与生活质量方面的统计学和临床显著改善有关。
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引用次数: 192
Patient-doctor communication: use of complementary and alternative medicine by adult patients with cancer. 医患沟通:成年癌症患者使用补充和替代医学。
Byeongsang Oh, Phyllis Butow, Barbara Mullan, Stephen Clarke, Martin Tattersall, Michael Boyer, Philip Beale, Janette Vardy, Nick Pavlakis, Linda Larke

The purpose of this survey was to examine patient-doctor communication about the use of complementary and alternative medicine (CAM) by adult patients with cancer and compare patients' satisfaction with the consultation between patients who had and those who had not discussed the use of CAM with their doctors. Oncologists from three hospitals screened patients for eligibility. Eligible patients were mailed a letter of invitation with a questionnaire (N = 1,323). Three hundred eighty-one questionnaires were returned. Sixty-five percent of cancer patients used at least one form of CAM. Use of CAM was not discussed with the oncologist by 55% of respondents using biologically based CAM and by 80% of those using non-biologically based CAM since the diagnosis of cancer. Patients who discussed the use of biologic CAM with their oncologists were more satisfied with the consultation than those who had not (p = .027), whereas there were no significant differences between patients who discussed or did not discuss use of non-biologically based CAM (p = .102). A substantial proportion of cancer patients do not discuss the use of CAM with their oncologists. It is important to improve patient-doctor communication about the use of CAM to increase patients' satisfaction with the oncology consultation.

本调查的目的是检查成年癌症患者使用辅助替代医学(CAM)的医患沟通情况,并比较有和没有与医生讨论过使用辅助替代医学的患者对咨询的满意度。来自三家医院的肿瘤学家筛选了患者的资格。向符合条件的患者邮寄邀请函和问卷(N = 1323)。共收回了381份问卷。65%的癌症患者至少使用一种CAM。自诊断癌症以来,55%使用生物基础CAM的受访者和80%使用非生物基础CAM的受访者没有与肿瘤学家讨论CAM的使用。与肿瘤学家讨论生物辅助治疗的患者比未讨论生物辅助治疗的患者对咨询更满意(p = 0.027),而讨论或未讨论非生物辅助治疗的患者之间没有显著差异(p = 0.102)。相当大比例的癌症患者不与肿瘤科医生讨论辅助治疗的使用。提高辅助医学的医患沟通对提高患者对肿瘤会诊的满意度具有重要意义。
{"title":"Patient-doctor communication: use of complementary and alternative medicine by adult patients with cancer.","authors":"Byeongsang Oh,&nbsp;Phyllis Butow,&nbsp;Barbara Mullan,&nbsp;Stephen Clarke,&nbsp;Martin Tattersall,&nbsp;Michael Boyer,&nbsp;Philip Beale,&nbsp;Janette Vardy,&nbsp;Nick Pavlakis,&nbsp;Linda Larke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this survey was to examine patient-doctor communication about the use of complementary and alternative medicine (CAM) by adult patients with cancer and compare patients' satisfaction with the consultation between patients who had and those who had not discussed the use of CAM with their doctors. Oncologists from three hospitals screened patients for eligibility. Eligible patients were mailed a letter of invitation with a questionnaire (N = 1,323). Three hundred eighty-one questionnaires were returned. Sixty-five percent of cancer patients used at least one form of CAM. Use of CAM was not discussed with the oncologist by 55% of respondents using biologically based CAM and by 80% of those using non-biologically based CAM since the diagnosis of cancer. Patients who discussed the use of biologic CAM with their oncologists were more satisfied with the consultation than those who had not (p = .027), whereas there were no significant differences between patients who discussed or did not discuss use of non-biologically based CAM (p = .102). A substantial proportion of cancer patients do not discuss the use of CAM with their oncologists. It is important to improve patient-doctor communication about the use of CAM to increase patients' satisfaction with the oncology consultation.</p>","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"8 2","pages":"56-64"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28919531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Team science of nursing, engineering, statistics, and practitioner in the development of a robotic reflexology device. 团队科学护理,工程,统计,和从业者在机器人反射装置的发展。
Gwen Wyatt, Alla Sikorskii, Tamara Reid Bush, Ranjan Mukherjee

The purpose of this article is to share the lessons learned in forming an interdisciplinary team that implements a team science approach to integrative medicine (IM) research. The disciplines of nursing, statistics, and engineering, along with consultants and a reflexology practitioner, formed this university-based team to conceptualize and develop a prototype robotic device for reflexology for breast cancer patients. The nurse investigator contributed the intervention background and access to the population; the statistician guided the team thinking on factors that needed to be controlled for; the engineers provided the expertise in device design and development; consultants facilitated the team's thinking in new directions; and the reflexology practitioner prescribed the protocol. We discuss the contributions and achievements of each discipline, as well as the challenges, and share the team experiences with the intent to help guide the formation of new IM teams that promote a conducive atmosphere for carrying out cutting-edge IM research and advancing the science.

本文的目的是分享组建跨学科团队的经验教训,以实现团队科学方法进行中西医结合(IM)研究。护理学、统计学和工程学的学科,以及顾问和反射疗法从业者,组成了这个以大学为基础的团队,为乳腺癌患者的反射疗法设计和开发了一个原型机器人设备。护士调查员提供了干预背景和人群获取途径;统计学家引导团队思考需要控制的因素;工程师们提供了设备设计和开发方面的专业知识;顾问帮助团队朝着新的方向思考;按摩师制定了治疗方案。我们讨论每个学科的贡献和成就,以及面临的挑战,并分享团队经验,旨在帮助指导新的IM团队的形成,促进开展尖端IM研究和推进科学的有利氛围。
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引用次数: 0
Patients Increasingly Want An Integrative Approach to Their Cancer Care: A Radiation Oncologist's Perspective. 病人越来越需要一个综合的方法来治疗他们的癌症:一个放射肿瘤学家的观点。
Brian Douglas Lawenda
{"title":"Patients Increasingly Want An Integrative Approach to Their Cancer Care: A Radiation Oncologist's Perspective.","authors":"Brian Douglas Lawenda","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"8 2","pages":"33-4"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28919528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Panax ginseng. 人参。
{"title":"Panax ginseng.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":87409,"journal":{"name":"Journal of the Society for Integrative Oncology","volume":"8 1","pages":"31-2"},"PeriodicalIF":0.0,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28755551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of the Society for Integrative Oncology
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