首页 > 最新文献

Cases journal最新文献

英文 中文
Management of suicidal cut throat injuries in a developing nation: three case reports. 发展中国家自杀割喉伤的处理:三例报告。
Pub Date : 2010-02-22 DOI: 10.1186/1757-1626-3-65
Adeyi A Adoga, Nuhu D Ma'an, Henry Y Embu, Taiwo J Obindo

Introduction: Suicidal cut throat injuries are either unreported or fortunately rare in our country. The management of these injuries requires a multi-disciplinary approach.

Case presentations: This paper presents our experiences with managing three unemployed adult Nigerian males - two of Hausa ethnicity and one from the Tiv ethnic group presenting with cut throat injuries following suicidal attempts.

Conclusion: The purpose of these reports is to emphasize that suicidal cut throat injuries do occur in our environment and there is a need for the collaboration of the otorhinolaryngologist, anesthesiologist and psychiatrist in the effective management of these patients. We recommend the socioeconomic improvement of individuals as a way of reducing the incidence of these injuries as unemployment was cited as a motivating factor for suicide in our patients. Ways must also be found to identify the many people in society without mental disorders who are at risk of suicidal behaviors.

导读:自杀式割喉伤害在我国要么没有报道,要么很罕见。这些损伤的处理需要多学科的方法。案例介绍:本文介绍了我们处理三名失业的尼日利亚成年男性的经验-两名豪萨族和一名Tiv族在自杀未遂后出现喉咙割伤。结论:本报告的目的是强调自杀性割喉伤在我们的环境中确实存在,需要耳鼻喉科医师、麻醉科医师和精神科医师的合作来有效地管理这些患者。我们建议提高个人的社会经济水平,以减少这些伤害的发生率,因为失业被认为是我们患者自杀的一个激励因素。还必须找到方法来识别社会上许多没有精神障碍但有自杀行为风险的人。
{"title":"Management of suicidal cut throat injuries in a developing nation: three case reports.","authors":"Adeyi A Adoga,&nbsp;Nuhu D Ma'an,&nbsp;Henry Y Embu,&nbsp;Taiwo J Obindo","doi":"10.1186/1757-1626-3-65","DOIUrl":"https://doi.org/10.1186/1757-1626-3-65","url":null,"abstract":"<p><strong>Introduction: </strong>Suicidal cut throat injuries are either unreported or fortunately rare in our country. The management of these injuries requires a multi-disciplinary approach.</p><p><strong>Case presentations: </strong>This paper presents our experiences with managing three unemployed adult Nigerian males - two of Hausa ethnicity and one from the Tiv ethnic group presenting with cut throat injuries following suicidal attempts.</p><p><strong>Conclusion: </strong>The purpose of these reports is to emphasize that suicidal cut throat injuries do occur in our environment and there is a need for the collaboration of the otorhinolaryngologist, anesthesiologist and psychiatrist in the effective management of these patients. We recommend the socioeconomic improvement of individuals as a way of reducing the incidence of these injuries as unemployment was cited as a motivating factor for suicide in our patients. Ways must also be found to identify the many people in society without mental disorders who are at risk of suicidal behaviors.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"65"},"PeriodicalIF":0.0,"publicationDate":"2010-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-65","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28729770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Acute Subarachnoid Hemorrhage and Cardiac Abnormalities: Takotsubo Cardiomyopathy or Neurogenic Stunned Myocardium? a case report. 急性蛛网膜下腔出血与心脏异常:Takotsubo型心肌病还是神经源性休克心肌?一份病例报告。
Pub Date : 2010-02-20 DOI: 10.1186/1757-1626-3-81
C Franco, B Khaled, L Afonso, M Raufi

Introduction: Cardiac abnormalities can be seen with subarachnoid hemorrhage. To date, there have been isolated case reports of transient left ventricular apical ballooning cardiomyopathy, also known as Takotsubo cardiomyopathy in patients suffering from subarachnoid hemorrhage.

Case presentation: An adult female was brought to the emergency department with somnolence. A 3 x 3 mm ruptured basilar aneurysm was found and successfully embolized. Two days after the patient developed acute heart failure. Troponin-I was elevated to 4.2 (normal <0.4). On ECG, new symmetric T wave inversion in V3, V4, V5 with prolonged QT were evident. Transthoracic echocardiogram showed severe systolic dysfunction with an ejection fraction of 20% and akinetic apex along with the distal left ventricular segments, consistent with Takotsubo cardiomyopathy. Myocardial contrast echocardiography showed a decrease in capillary blood flow and volume in the akinetic areas with delayed contrast replenishment, sparing the basal segments. A repeat study 2 weeks later showed near normalization of the perfusion parameters. The patient improved with medical management. A repeat echocardiogram, a month later revealed an ejection fraction of 45% with no identifiable wall motion abnormality.

Conclusion: Our case, as well as others reported previously, supports the diagnosis of Takotsubo cardiomyopathy in patients with Subarachnoid Hemorrhage who fulfill the clinical and imaging description of this syndrome.

导语:蛛网膜下腔出血可引起心脏异常。迄今为止,在蛛网膜下腔出血患者中有短暂性左室心尖球囊性心肌病,也称为Takotsubo心肌病的孤立病例报告。病例介绍:一名成年女性因嗜睡被送到急诊科。发现一个3 × 3毫米破裂的基底动脉瘤并成功栓塞。两天后,病人出现了急性心力衰竭。结论:我们的病例,以及之前报道的其他病例,支持蛛网膜下腔出血患者Takotsubo心肌病的诊断,这些患者符合该综合征的临床和影像学描述。
{"title":"Acute Subarachnoid Hemorrhage and Cardiac Abnormalities: Takotsubo Cardiomyopathy or Neurogenic Stunned Myocardium? a case report.","authors":"C Franco,&nbsp;B Khaled,&nbsp;L Afonso,&nbsp;M Raufi","doi":"10.1186/1757-1626-3-81","DOIUrl":"https://doi.org/10.1186/1757-1626-3-81","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiac abnormalities can be seen with subarachnoid hemorrhage. To date, there have been isolated case reports of transient left ventricular apical ballooning cardiomyopathy, also known as Takotsubo cardiomyopathy in patients suffering from subarachnoid hemorrhage.</p><p><strong>Case presentation: </strong>An adult female was brought to the emergency department with somnolence. A 3 x 3 mm ruptured basilar aneurysm was found and successfully embolized. Two days after the patient developed acute heart failure. Troponin-I was elevated to 4.2 (normal <0.4). On ECG, new symmetric T wave inversion in V3, V4, V5 with prolonged QT were evident. Transthoracic echocardiogram showed severe systolic dysfunction with an ejection fraction of 20% and akinetic apex along with the distal left ventricular segments, consistent with Takotsubo cardiomyopathy. Myocardial contrast echocardiography showed a decrease in capillary blood flow and volume in the akinetic areas with delayed contrast replenishment, sparing the basal segments. A repeat study 2 weeks later showed near normalization of the perfusion parameters. The patient improved with medical management. A repeat echocardiogram, a month later revealed an ejection fraction of 45% with no identifiable wall motion abnormality.</p><p><strong>Conclusion: </strong>Our case, as well as others reported previously, supports the diagnosis of Takotsubo cardiomyopathy in patients with Subarachnoid Hemorrhage who fulfill the clinical and imaging description of this syndrome.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"81"},"PeriodicalIF":0.0,"publicationDate":"2010-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-81","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28932044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Modified lateral rhinotomy for fronto-ethmoid schwannoma in a child: a case report. 改良侧鼻切开术治疗儿童额筛神经鞘瘤1例。
Pub Date : 2010-02-18 DOI: 10.1186/1757-1626-3-64
Anurag Ramavat, Rakesh Kumar, C Venkatakarthikeyan, Ayushi Jain, Ramesh C Deka

Schwannoma of frontoethmoid region is a rare presentation. We report a case of 11-year-old girl with a swelling at the root of nose and nasal dorsum. Based on clinical picture and radiological findings it was not possible to establish a definitive diagnosis. But the histopathological picture was suggestive of schwannoma. A novel surgical approach was adopted to facilitate complete removal of the tumor and provide best possible cosmetic results.

额筛区神经鞘瘤是一种罕见的表现。我们报告一例11岁的女孩在鼻根和鼻背肿胀。根据临床表现和放射学表现,不可能建立明确的诊断。但病理组织学提示为神经鞘瘤。采用了一种新颖的手术方法,以促进肿瘤的完全切除,并提供最佳的美容效果。
{"title":"Modified lateral rhinotomy for fronto-ethmoid schwannoma in a child: a case report.","authors":"Anurag Ramavat,&nbsp;Rakesh Kumar,&nbsp;C Venkatakarthikeyan,&nbsp;Ayushi Jain,&nbsp;Ramesh C Deka","doi":"10.1186/1757-1626-3-64","DOIUrl":"https://doi.org/10.1186/1757-1626-3-64","url":null,"abstract":"<p><p> Schwannoma of frontoethmoid region is a rare presentation. We report a case of 11-year-old girl with a swelling at the root of nose and nasal dorsum. Based on clinical picture and radiological findings it was not possible to establish a definitive diagnosis. But the histopathological picture was suggestive of schwannoma. A novel surgical approach was adopted to facilitate complete removal of the tumor and provide best possible cosmetic results.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"64"},"PeriodicalIF":0.0,"publicationDate":"2010-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-64","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28722233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Ophthalmic complications of endoscopic ethmoidectomy: a case report. 内镜下筛切除术的眼并发症1例。
Pub Date : 2010-02-18 DOI: 10.1186/1757-1626-3-63
Iwona Niedzielska, Tadeusz Cieslik, Tomasz Janic

Damage to ethmoid structures following removal of nasal polyps can cause severe complications. A patient aged 48 years with damage to right orbital structures sustained in the course of transnasal endoscopic surgery for ethmoid polyps was operated. After operation were complications.

鼻息肉切除后对筛结构的损伤可引起严重的并发症。一例48岁的患者在经鼻内镜手术治疗筛窦息肉的过程中右眼眶结构受损。术后出现并发症。
{"title":"Ophthalmic complications of endoscopic ethmoidectomy: a case report.","authors":"Iwona Niedzielska,&nbsp;Tadeusz Cieslik,&nbsp;Tomasz Janic","doi":"10.1186/1757-1626-3-63","DOIUrl":"https://doi.org/10.1186/1757-1626-3-63","url":null,"abstract":"<p><p> Damage to ethmoid structures following removal of nasal polyps can cause severe complications. A patient aged 48 years with damage to right orbital structures sustained in the course of transnasal endoscopic surgery for ethmoid polyps was operated. After operation were complications.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2010-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-63","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28722298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Repair of a defect following the removal of an impacted maxillary canine by orthodontic tooth movement: a case report. 正畸牙齿移动去除阻生上颌犬齿后缺损的修复:1例报告。
Pub Date : 2010-02-15 DOI: 10.1186/1757-1626-3-62
Wai Yip Lei, A Bakr M Rabie, Ricky Wk Wong

This case report describes a 13-year-old boy with alveolar bony defect resulted from surgical removal of impacted upper canine transposed in the anterior region. The boy had a normal occlusion with malposition of upper central and lateral incisors. The treatment objectives were to align teeth, close spaces by mesial movement of the buccal segments in the upper jaw to repair bone loss. Fixed appliance with palatal root torque was used for the mesial movements, levelling, and alignment of teeth.Orthodontic tooth movement consisted of a sequence of root movement in a direction to increase the thickness of the labial cortical plate of bone, could ensure healthier periodontium. A healthier periodontium prior to space closure ensured repair of alveolar bony defect after surgical intervention. Orthodontic tooth movement should be added to our armamentarium for the repair of alveolar bony defect.

这个病例报告描述了一个13岁男孩的牙槽骨缺损,由于手术切除了在前区转位的上犬牙。男童牙合正常,上、中、侧切牙错位。治疗目标是通过上颌颊段的近中运动来排列牙齿,关闭间隙以修复骨质流失。固定矫治器与腭根扭矩用于近中移动,水平和对准牙齿。正畸牙的运动由牙根沿一定方向的顺序运动组成,增加唇骨皮质板的厚度,可以保证牙周组织的健康。在间隙闭合之前,健康的牙周组织确保了手术干预后牙槽骨缺损的修复。在修复牙槽骨缺损时,应增加正畸牙齿活动。
{"title":"Repair of a defect following the removal of an impacted maxillary canine by orthodontic tooth movement: a case report.","authors":"Wai Yip Lei,&nbsp;A Bakr M Rabie,&nbsp;Ricky Wk Wong","doi":"10.1186/1757-1626-3-62","DOIUrl":"https://doi.org/10.1186/1757-1626-3-62","url":null,"abstract":"<p><p>This case report describes a 13-year-old boy with alveolar bony defect resulted from surgical removal of impacted upper canine transposed in the anterior region. The boy had a normal occlusion with malposition of upper central and lateral incisors. The treatment objectives were to align teeth, close spaces by mesial movement of the buccal segments in the upper jaw to repair bone loss. Fixed appliance with palatal root torque was used for the mesial movements, levelling, and alignment of teeth.Orthodontic tooth movement consisted of a sequence of root movement in a direction to increase the thickness of the labial cortical plate of bone, could ensure healthier periodontium. A healthier periodontium prior to space closure ensured repair of alveolar bony defect after surgical intervention. Orthodontic tooth movement should be added to our armamentarium for the repair of alveolar bony defect.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"62"},"PeriodicalIF":0.0,"publicationDate":"2010-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-62","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29021114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Community acquired methicillin-resistant Staphylococcus aureus pneumonia leading to rhabdomyolysis: a case report. 社区获得性耐甲氧西林金黄色葡萄球菌肺炎致横纹肌溶解1例报告。
Pub Date : 2010-02-14 DOI: 10.1186/1757-1626-3-61
Poorani Nallam Goundan, Anurag Mehrotra, Deepa Mani, Indumathy Varadarajan

Community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) is considered an underreported entity in India. In this case report, the authors describe a thirty-five year old immunocompetent male presenting with severe respiratory distress requiring intubation. On further work up, a CT thorax showed features consistent with necrotizing pneumonia. The morphology and sensitivity pattern of the organism found in the bronchoalveolar lavage fluid and blood culture were consistent with MRSA. The patient's stay in the hospital was complicated by acute renal failure due to rhabdomyolysis with CPK levels of 9995 U/L. The patient was started on dialysis and improved there after. This case brings to light that CA-MRSA is becoming a problem in developing nations where antibiotics are frequently used empirically with little laboratory guidance. It also is a rare reporting of rhabdomyolysis due to CA-MRSA.

社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)被认为是印度报告不足的实体。在这个病例报告中,作者描述了一个35岁的免疫功能正常的男性表现为严重的呼吸窘迫需要插管。进一步检查,胸部CT显示坏死性肺炎的特征。在支气管肺泡灌洗液和血培养中发现的微生物的形态和敏感性模式与MRSA一致。患者住院期间合并横纹肌溶解急性肾功能衰竭,CPK水平为9995 U/L。病人开始接受透析治疗,此后病情有所好转。这一案例表明,CA-MRSA正在成为发展中国家的一个问题,在这些国家,抗生素的使用经常是经验性的,几乎没有实验室指导。这也是一个罕见的报告横纹肌溶解由于CA-MRSA。
{"title":"Community acquired methicillin-resistant Staphylococcus aureus pneumonia leading to rhabdomyolysis: a case report.","authors":"Poorani Nallam Goundan,&nbsp;Anurag Mehrotra,&nbsp;Deepa Mani,&nbsp;Indumathy Varadarajan","doi":"10.1186/1757-1626-3-61","DOIUrl":"https://doi.org/10.1186/1757-1626-3-61","url":null,"abstract":"<p><p> Community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) is considered an underreported entity in India. In this case report, the authors describe a thirty-five year old immunocompetent male presenting with severe respiratory distress requiring intubation. On further work up, a CT thorax showed features consistent with necrotizing pneumonia. The morphology and sensitivity pattern of the organism found in the bronchoalveolar lavage fluid and blood culture were consistent with MRSA. The patient's stay in the hospital was complicated by acute renal failure due to rhabdomyolysis with CPK levels of 9995 U/L. The patient was started on dialysis and improved there after. This case brings to light that CA-MRSA is becoming a problem in developing nations where antibiotics are frequently used empirically with little laboratory guidance. It also is a rare reporting of rhabdomyolysis due to CA-MRSA.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"61"},"PeriodicalIF":0.0,"publicationDate":"2010-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-61","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28755537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Interstitial lung disease associated to erlotinib treatment: a case report. 厄洛替尼治疗相关间质性肺疾病1例报告
Pub Date : 2010-02-12 DOI: 10.1186/1757-1626-3-59
Yolanda Del Castillo, Paulina Espinosa, Fernanda Bodí, Raquel Alcega, Emma Muñoz, Carlos Rabassó, David Castander

Introduction: Few cases of pulmonary toxicity related to epidermal growth factor receptor-targeted agents have been described.

Case presentation: We report a case of a 63-year-old white male with stage IV non-small cell lung cancer treated with erlotinib who developed a interstitial lung disease.

Conclusion: Respiratory symptoms during treatment with erlotinib should alert clinicians to rule out pulmonary toxicity. Early erlotinib withdrawal and corticoid administration were successful.

引言:与表皮生长因子受体靶向药物相关的肺毒性病例很少。病例介绍:我们报告一例63岁白人男性IV期非小细胞肺癌,经厄洛替尼治疗后发展为间质性肺疾病。结论:厄洛替尼治疗期间出现的呼吸道症状应提醒临床医生排除肺毒性。早期厄洛替尼停药和皮质激素治疗成功。
{"title":"Interstitial lung disease associated to erlotinib treatment: a case report.","authors":"Yolanda Del Castillo,&nbsp;Paulina Espinosa,&nbsp;Fernanda Bodí,&nbsp;Raquel Alcega,&nbsp;Emma Muñoz,&nbsp;Carlos Rabassó,&nbsp;David Castander","doi":"10.1186/1757-1626-3-59","DOIUrl":"https://doi.org/10.1186/1757-1626-3-59","url":null,"abstract":"<p><strong>Introduction: </strong>Few cases of pulmonary toxicity related to epidermal growth factor receptor-targeted agents have been described.</p><p><strong>Case presentation: </strong>We report a case of a 63-year-old white male with stage IV non-small cell lung cancer treated with erlotinib who developed a interstitial lung disease.</p><p><strong>Conclusion: </strong>Respiratory symptoms during treatment with erlotinib should alert clinicians to rule out pulmonary toxicity. Early erlotinib withdrawal and corticoid administration were successful.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2010-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-59","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29020991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Stiff limb syndrome: a case report. 四肢僵硬综合征1例报告。
Pub Date : 2010-02-12 DOI: 10.1186/1757-1626-3-60
Abderrazak Hajjioui, Karima Benbouazza, Mohamed El Alaoui Faris, Amina Missaoui, Najia Hajjaj Hassouni

Introduction: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature.

Case presentation: A 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg/day and baclofen 30 mg/day.

Conclusion: This clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography.

肢体僵硬综合征是僵硬人综合征的临床特征,是一种罕见的致残性神经系统疾病,以肌肉僵硬和发作性痉挛为特征,累及轴肢肌肉组织。它是一种自身免疫性疾病,导致中枢神经系统中氨基丁酸介导的抑制网络功能障碍。我们描述了一个病人的神经症状诊断为肢体僵硬综合征与治疗后良好的结果,并回顾了相关文献。病例介绍:一名49岁男性患者,表现为进行性僵硬和双腿疼痛痉挛,站立和行走困难。使用地西泮(25mg /天)和巴氯芬(30mg /天)治疗的显著阳性反应支持了肢体僵硬综合征的诊断。结论:本病例强调了治疗性检查对确定肢体僵硬综合征诊断的重要性,特别是当临床怀疑肌电图不明显时。
{"title":"Stiff limb syndrome: a case report.","authors":"Abderrazak Hajjioui,&nbsp;Karima Benbouazza,&nbsp;Mohamed El Alaoui Faris,&nbsp;Amina Missaoui,&nbsp;Najia Hajjaj Hassouni","doi":"10.1186/1757-1626-3-60","DOIUrl":"https://doi.org/10.1186/1757-1626-3-60","url":null,"abstract":"<p><strong>Introduction: </strong>Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature.</p><p><strong>Case presentation: </strong>A 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg/day and baclofen 30 mg/day.</p><p><strong>Conclusion: </strong>This clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"60"},"PeriodicalIF":0.0,"publicationDate":"2010-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-60","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28755535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Occult small bowel perforation in a patient with Ehlers Danlos syndrome: a case report and review of the literature. Ehlers - Danlos综合征患者隐匿性小肠穿孔1例报告及文献复习。
Pub Date : 2010-02-12 DOI: 10.1186/1757-1626-3-57
Tessa Frances Leake, Tarun Singhal, Aninda Chandra, Alexandra Ashcroft, Sudeendra Doddi, Abdulzahra Hussain, Frank Smedley

Patients who present with a co-existing connective tissue disorder add a degree of complexity to operative intervention. We present an unusual case of a 53-year-old Caucasian female patient with Ehlers Danlos syndrome who presented with an occult perforation of the distal ileum. The patient had known small bowel diverticulae yet the perforation occurred within the normal bowel wall. The pre-operative CT only showed malrotation of the large bowel and did not correlate with the intra-operative findings. Our case has highlighted that although small bowel perforation is a rare occurrence, it may be more common in Ehlers Danlos and may present with atypical features. Perforation may also occur alongside normal bowel as well as diverticulae within the bowel. Where diverticulae exists within a patient with Ehlers Danlos syndrome and there is some diagnostic uncertainty, there should be a lower threshold for operative intervention. We present in the discussion a number of salient features and learning points.

同时存在结缔组织疾病的患者增加了手术干预的复杂性。我们提出一个不寻常的情况下,53岁的高加索女性患者Ehlers Danlos综合征谁提出了一个隐匿穿孔的远回肠。患者已知小肠憩室,但穿孔发生在正常肠壁内。术前CT仅显示大肠旋转不良,与术中表现无关。我们的病例强调,虽然小肠穿孔是罕见的,但它可能在Ehlers Danlos中更常见,并可能表现出不典型的特征。穿孔也可能发生在正常肠和肠内憩室旁。当Ehlers Danlos综合征患者存在憩室且诊断不确定时,应降低手术干预的门槛。我们在讨论中提出了一些突出的特点和学习要点。
{"title":"Occult small bowel perforation in a patient with Ehlers Danlos syndrome: a case report and review of the literature.","authors":"Tessa Frances Leake,&nbsp;Tarun Singhal,&nbsp;Aninda Chandra,&nbsp;Alexandra Ashcroft,&nbsp;Sudeendra Doddi,&nbsp;Abdulzahra Hussain,&nbsp;Frank Smedley","doi":"10.1186/1757-1626-3-57","DOIUrl":"https://doi.org/10.1186/1757-1626-3-57","url":null,"abstract":"<p><p> Patients who present with a co-existing connective tissue disorder add a degree of complexity to operative intervention. We present an unusual case of a 53-year-old Caucasian female patient with Ehlers Danlos syndrome who presented with an occult perforation of the distal ileum. The patient had known small bowel diverticulae yet the perforation occurred within the normal bowel wall. The pre-operative CT only showed malrotation of the large bowel and did not correlate with the intra-operative findings. Our case has highlighted that although small bowel perforation is a rare occurrence, it may be more common in Ehlers Danlos and may present with atypical features. Perforation may also occur alongside normal bowel as well as diverticulae within the bowel. Where diverticulae exists within a patient with Ehlers Danlos syndrome and there is some diagnostic uncertainty, there should be a lower threshold for operative intervention. We present in the discussion a number of salient features and learning points.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"57"},"PeriodicalIF":0.0,"publicationDate":"2010-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-57","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28755602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Upper gastrointestinal bleeding due to gastric stromal tumour: a case report. 胃间质瘤致上消化道出血1例。
Pub Date : 2010-02-12 DOI: 10.1186/1757-1626-3-58
Tarun Singhal, Sudeendra Doddi, Tessa Leake, Srikanth Parsi, Abdulzahra Hussain, Aninda Chandra, Frank Smedley, Joe Ellul

Introduction: Gastro-intestinal stromal tumours are the most common mesenchymal tumours of the gastro-intestinal tract. This case report highlights the necessity of early surgical intervention in such cases to avoid mortality due to rebleeding and to raise the awareness of rare causes of upper gastrointestinal bleed and their management.

Case presentation: A 61-year-old male presented to the accident and emergency department with a one-day history of haemetemesis with coffee ground vomiting. After initial resuscitation, he underwent upper gastrointestinal endoscopy under sedation which demonstrated a large, bleeding, gastric mass with a central crater along the greater curvature of the stomach. A partial gastrectomy was performed taking a wedge of the stomach with clearance from the tumour, with no signs of extraperitoneal disease.

Conclusion: Early surgical intervention, either open or laparoscopic resection, is the treatment of choice to prevent rebleeds. In general, complete surgical resection is accomplished in 40-60% of all gastro-intestinal stromal tumours patients, and in >70% of those with primary non- metastatic gastro-intestinal stromal tumour. In our case we had completely excised the tumour. Following surgery, all patients must be referred to centres which have more experience in treating gastro-intestinal stromal tumours. Imatinib is proven to be the first effective systemic therapy in cases of unresectable or metastatic disease. All gastro-intestinal stromal tumours have the potential for aggressive behaviour with the risk being estimated from tumour size and mitotic count.

胃肠道间质瘤是胃肠道最常见的间质肿瘤。本病例报告强调在此类病例中早期手术干预的必要性,以避免因再出血而死亡,并提高对上消化道出血罕见原因及其处理的认识。病例介绍:一名61岁男性,因一日呕血伴咖啡渣呕吐到急诊科就诊。初步复苏后,患者在镇静状态下接受上消化道内窥镜检查,结果显示有一个大的出血胃团块,沿胃大弯曲处有一个中央凹坑。在肿瘤清除的情况下,进行了部分胃切除术,没有发现腹膜外疾病的迹象。结论:早期手术干预,无论是开放还是腹腔镜切除,都是预防再出血的首选治疗方法。一般来说,40-60%的胃肠道间质瘤患者和>70%的原发性非转移性胃肠道间质瘤患者完成了完全手术切除。在我们的病例中,我们已经完全切除了肿瘤。手术后,所有患者必须转诊到在治疗胃肠道间质瘤方面更有经验的中心。伊马替尼被证明是治疗不可切除或转移性疾病的第一种有效的全身疗法。所有胃肠道间质瘤都有潜在的侵袭性行为,其风险可从肿瘤大小和有丝分裂计数来估计。
{"title":"Upper gastrointestinal bleeding due to gastric stromal tumour: a case report.","authors":"Tarun Singhal,&nbsp;Sudeendra Doddi,&nbsp;Tessa Leake,&nbsp;Srikanth Parsi,&nbsp;Abdulzahra Hussain,&nbsp;Aninda Chandra,&nbsp;Frank Smedley,&nbsp;Joe Ellul","doi":"10.1186/1757-1626-3-58","DOIUrl":"https://doi.org/10.1186/1757-1626-3-58","url":null,"abstract":"<p><strong>Introduction: </strong>Gastro-intestinal stromal tumours are the most common mesenchymal tumours of the gastro-intestinal tract. This case report highlights the necessity of early surgical intervention in such cases to avoid mortality due to rebleeding and to raise the awareness of rare causes of upper gastrointestinal bleed and their management.</p><p><strong>Case presentation: </strong>A 61-year-old male presented to the accident and emergency department with a one-day history of haemetemesis with coffee ground vomiting. After initial resuscitation, he underwent upper gastrointestinal endoscopy under sedation which demonstrated a large, bleeding, gastric mass with a central crater along the greater curvature of the stomach. A partial gastrectomy was performed taking a wedge of the stomach with clearance from the tumour, with no signs of extraperitoneal disease.</p><p><strong>Conclusion: </strong>Early surgical intervention, either open or laparoscopic resection, is the treatment of choice to prevent rebleeds. In general, complete surgical resection is accomplished in 40-60% of all gastro-intestinal stromal tumours patients, and in >70% of those with primary non- metastatic gastro-intestinal stromal tumour. In our case we had completely excised the tumour. Following surgery, all patients must be referred to centres which have more experience in treating gastro-intestinal stromal tumours. Imatinib is proven to be the first effective systemic therapy in cases of unresectable or metastatic disease. All gastro-intestinal stromal tumours have the potential for aggressive behaviour with the risk being estimated from tumour size and mitotic count.</p>","PeriodicalId":87572,"journal":{"name":"Cases journal","volume":"3 ","pages":"58"},"PeriodicalIF":0.0,"publicationDate":"2010-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/1757-1626-3-58","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29020992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
期刊
Cases journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1