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Impact of housing instability on child behavior at age 7. 住房不稳定对7岁儿童行为的影响。
Abigail L Gaylord, Whitney J Cowell, Lori A Hoepner, Frederica P Perera, Virginia A Rauh, Julie B Herbstman

Housing instability is a thought to be a major influence on children's healthy growth and development. However, little is known about the factors that influence housing instability, limiting the identification of effective interventions. The goals of this study were to 1) explore factors, including material hardship, satisfaction with living conditions and housing disrepair, that predict housing instability (total number of moves that a child experienced in the first seven years); and 2) examine the relationship between housing instability and child behavior at age 7, measured by the Child Behavior Checklist. We analyzed these associations among children enrolled in the Columbia Center for Children's Environmental Health (CCCEH) Mothers and Newborns study. In our analysis, we found that housing disrepair predicted residential change after 3 years of age, but not before. Persistent material hardship over the seven-year time period from pregnancy through age 7 was associated with increased number of moves. Children who experienced more than three moves in the first 7 years had significantly more thought- and attention-related problems compared to children who experienced less than 3 moves over the same time period. Children who experienced more than 3 moves also had higher total and internalizing problem behavior scores, although these differences were not statistically significant. We conclude that housing instability is significantly associated with problem behavior in early childhood and that interventions to reduce socioeconomic strain may have the greatest impact in breaking the cycle of children's environmental health disparities related to housing instability.

住房不稳定被认为是影响儿童健康成长和发展的主要因素。然而,对影响住房不稳定的因素知之甚少,限制了有效干预措施的确定。本研究的目的是:(1)探索预测住房不稳定性的因素,包括物质困难、对生活条件的满意度和住房年久失修(儿童在前7年经历的总搬家次数);2)检验住房不稳定性与7岁儿童行为之间的关系(用儿童行为检查表测量)。我们在哥伦比亚儿童环境健康中心(CCCEH)母亲和新生儿研究中对这些关联进行了分析。在我们的分析中,我们发现房屋年久失修预测了3年后的居住变化,而不是之前。从怀孕到7岁的7年时间里,持续的物质困难与搬家次数的增加有关。在头7年里经历了3次以上移动的孩子与在同一时期经历了少于3次移动的孩子相比,有更多的思维和注意力相关问题。经历过3次以上动作的儿童也有更高的总和内化问题行为得分,尽管这些差异没有统计学意义。我们的结论是,住房不稳定与儿童早期的问题行为显著相关,减少社会经济压力的干预措施可能对打破与住房不稳定相关的儿童环境健康差异的循环产生最大影响。
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引用次数: 0
Impact of the home environment on the relationship between prenatal exposure to environmental tobacco smoke and child behavior. 家庭环境对产前接触环境烟草烟雾与儿童行为之间关系的影响。
Madeleine B Hopson, Amy Margolis, Virginia Rauh, Julie Herbstman

The goal of this study was to ascertain whether the effect of prenatal ETS exposure on behavioral symptoms at age 7 years is modified by the quality of the home environment. In a cohort of 417 children enrolled in a longitudinal birth cohort in New York City, prenatal ETS exposure, child behavior and home environment were assessed. Prenatal ETS was measured by questionnaire and blood cotinine. Child Behavior Checklist (CBCL) and Early Childhood HOME Inventory Scale (HOME) were also used. We detected a significant interaction between prenatal ETS exposure and living in a "better" home environment on reported problems in the rule breaking and externalizing domains (p-value for interaction terms: 0.002 and 0.04, respectively), such that there was no significant adverse impact of ETS exposure on behavior among those who experienced a "better" environment. We also detected a significant interaction between prenatal ETS exposure and living in a "worse" home environment on reported problems in the aggressive and externalizing domains (p-value for interaction terms: 0.03 and 0.02, respectively), such that there was a significant adverse effect of ETS exposure on behavior among children who experienced a "worse" environment. Aspects of the HOME environment, both positive and negative, moderated the effects of prenatal ETS exposure on selected behaviors at 7 years of age. This finding suggests that some negative developmental behavioral effects associated with ETS exposure early in life may be modified by the provision of an enriched learning environment as measured by the HOME inventory.

本研究的目的是确定产前接触有毒有害物质对 7 岁儿童行为症状的影响是否会因家庭环境的质量而改变。在纽约市一个纵向出生队列中登记的 417 名儿童中,对产前接触 ETS、儿童行为和家庭环境进行了评估。产前 ETS 通过问卷和血液中的可替宁进行测量。此外,还使用了儿童行为量表(CBCL)和幼儿家庭环境量表(HOME)。我们发现,产前接触有毒有害物质与生活在 "较好 "的家庭环境之间存在明显的交互作用(交互作用项的 p 值分别为 0.002 和 0.04),因此,接触有毒有害物质对那些生活在 "较好 "环境中的儿童的行为没有明显的负面影响。我们还发现,产前接触 ETS 与生活在 "较差 "家庭环境中对所报告的攻击性和外化领域的问题有明显的交互作用(交互作用项的 p 值分别为 0.03 和 0.02),因此,接触 ETS 对生活在 "较差 "环境中的儿童的行为有明显的不利影响。家庭环境的积极和消极方面均可调节产前接触有毒有害物质对 7 岁儿童某些行为的影响。这一研究结果表明,通过 "居家 "环境调查表的测量,提供丰富的学习环境可能会改变与早年接触 ETS 相关的一些负面发育行为影响。
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引用次数: 0
Kinecting the moves: the kinematic potential of rehabilitation-specific gaming to inform treatment for hemiplegia 连接动作:康复特定游戏的运动学潜力,为偏瘫治疗提供信息
Pub Date : 2014-01-01 DOI: 10.14288/1.0075871
S. Glegg, Chai-Ting Hung, Bulmaro A. Valdés, Brandon D. G. Kim, H. V. D. Loos
IntroductionThe use of commercial gaming systems is gaining momentum in the field of rehabilitation (1). Virtual reality and active video games can increase user engagement and enjoyment in rehabilitation, increasing the potential for enhancing patient outcomes (2, 3). Therapeutic gaming may be one treatment tool selected by therapists for individuals with hemiparesis as a means of providing motivating opportunities for repetitive motor practice that encourages specific movement patterns and use of the impaired limb (4, 5). Bimanual therapy is an effective approach to reduce impairment and to improve functional ability of the paretic arm (6). However, commercial video games are not designed to consistently optimize the use of both arms simultaneously. Challenges exist, therefore, in the application of these systems to meet the therapeutic needs and physical capacities of different patient populations (7). Accordingly, the development of novel game applications and user interfaces for commercial gaming systems is expanding the potential for the technology to be adapted and integrated for these purposes, both in clinics and in the home.Motion tracking technology is being used increasingly both as a movement interface in these gaming systems, and as a means of capturing data about participants' kinematic movements during rehabilitation (8,9). The Vicon system (Oxford, UK) (10), the FASTRAK system (League City, TX) (11), and the Microsoft Kinect(TM) (Redmond, WA) (12) are three examples of this technology. The marker-based Vicon and FASTRAK systems provide higher accuracy compared to the Kinect, however at a higher cost and required expertise, making them unsuitable for most rehabilitation applications. Conversely, the Kinect has demonstrated centimetre-level accuracy, yet high correlations of tracked data with those obtained by marker-based systems (13). These findings, along with its commercial availability, make the Kinect a potential candidate for use in a clinical or home setting for rehabilitation. Furthermore, at this time, no documented guidance exists to translate the Kinect's kinematic data into clinically relevant information that is useful to therapists prescribing gaming interventions.The FEATHERS (Functional Engagement in Assisted Therapy through Exercise Robotics) project focuses on the development, testing and implementation of rehabilitation-specific interfaces for bimanual therapy, and the extraction of kinematic data to inform therapists monitoring patients' performance and progress. By applying custom algorithms to data collected from the Sony PlayStation Move (Tokyo, Japan) and the Kinect systems, it is possible to determine the total distance moved by the participant, their range of motion (ROM), and the vertical hand offsets for different directional movements. Moreover, the Kinect system is capable of providing data about excessive trunk movements.The purposes of this paper are therefore: (i) to describe the adaptation of two
商业游戏系统的使用正在康复领域获得动力(1)。虚拟现实和积极的视频游戏可以增加用户在康复中的参与度和乐趣,增加了改善患者结果的潜力(2)。3)治疗性游戏可能是治疗师为偏瘫患者选择的一种治疗工具,作为一种为重复运动练习提供激励机会的手段,鼓励特定的运动模式和使用受损肢体(4,5)。双手疗法是减少损伤和提高麻痹手臂功能能力的有效方法(6)。然而,商业电子游戏的设计并不是为了同时优化双臂的使用。因此,在这些系统的应用中存在挑战,以满足不同患者群体的治疗需求和身体能力(7)。因此,商业游戏系统的新型游戏应用程序和用户界面的开发正在扩大技术的潜力,以适应和整合这些目的,无论是在诊所还是在家庭。运动跟踪技术正越来越多地被用作这些游戏系统中的运动界面,以及作为捕获参与者在康复期间运动学运动数据的手段(8,9)。Vicon系统(Oxford, UK) (10), FASTRAK系统(League City, TX)(11)和Microsoft Kinect(TM) (Redmond, WA)(12)是这种技术的三个例子。与Kinect相比,基于标记的Vicon和FASTRAK系统提供了更高的精度,但成本更高,需要专业知识,因此不适合大多数康复应用。相反,Kinect已经证明了厘米级的精度,但跟踪数据与基于标记的系统获得的数据高度相关(13)。这些发现,再加上它的商业可行性,使Kinect成为临床或家庭康复治疗的潜在候选者。此外,目前还没有文献指导将Kinect的运动学数据转化为临床相关信息,从而帮助治疗师制定游戏干预处方。FEATHERS(通过运动机器人辅助治疗的功能参与)项目专注于开发、测试和实现用于双手治疗的康复特定接口,以及提取运动学数据以告知治疗师监测患者的表现和进展。通过将自定义算法应用于从索尼PlayStation Move(东京,日本)和Kinect系统收集的数据,可以确定参与者移动的总距离,他们的运动范围(ROM)以及不同方向运动的垂直手偏移量。此外,Kinect系统能够提供有关躯干过度运动的数据。因此,本文的目的是:(i)描述两个商业接口(PlayStation Move和Microsoft Kinect)的适应性,以促进在基于社交媒体的游戏中使用双边手臂;(ii)共享使用该系统的两名偏瘫患者的初步运动学数据。系统提供的运动学数据分析允许提取临床相关信息,这些信息可以与治疗师共享,以告知他们的治疗决策。方法为了将这两个动作捕捉接口用于偏瘫患者的上肢康复,开发了一个名为“FEATHERS motion”的计算机应用程序。羽毛运动应用程序依赖于使用在正面平面的双手运动来控制Windows®7个人计算机上的鼠标光标。两种运动模式(视觉对称和点镜像对称)可用于将移动最少的手映射到光标运动。在视觉对称模式下,用户需要同时向同一方向移动双手,而在点镜像对称模式下,用户必须围绕圆周移动双手,类似于转动方向盘。…
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引用次数: 12
Adolescent Mental Health 青少年心理健康
Pub Date : 2012-04-01 DOI: 10.4135/9781483369532.n9
D. Greydanus, J. Merrick
IntroductionMental or emotional problems of humans have probably existed ever since Homo sapiens emerged as a species (1). History notes medical treatments dating back to the Ebers Papyrus (1500 BCE) that lists over 700 medicines made from various sources-animal, vegetable, mineral, others (2). Scholars in China and India developed large pharmacopoeias dealing with various disorders over several thousands of years (3). However, the ancient philosopher, Aristotle (384-322 BCE), was quite skeptical of the powers of medicine as noted with his opine: "...the physician does not cure man, except in an incidental sense" (4).Distinguishing medical and psychological problems of children and adolescents required thousands of years of observation since most energy was spent on adult disorders. Health care advances usually were initially targeted for adults and gradually over the past 1,000 years, considered the health of children. Rhazes (Muhammad ibn Zakariya Razi [865-925 CE]) was the most famous physician of ancient Persia and his brilliant observations as well as writings initiated the birth of pediatric knowledge with his book on children's disorders at the same time that Western civilization knowledge was lost in the Dark Ages. Eventually those in the West emerged from their intellectual abyss with textbooks covering children by Trotula Platearius of Salerno, Italy (De Mylierum Passionibus) in 1050 CE and by Thomas Phaer in 1544 CE (The Boke of Chyldren). Thomas Phaer was an English pediatrician, lawyer, and author of the first book on pediatrics in the English language; this landmark treatise was the first to provide a distinction between the critical stages of childhood and adulthood setting the stage for further research on problems of childhood. Four centuries later, medical problems of children were finally appreciated with the formation of the American Academy of Pediatrics in 1930. The American Academy of Child Psychiatry was formed in 1953 to study psychiatric problems of children and the Journal of the American Academy of Child and Adolescent Psychiatry began in 1962 to record research discoveries in mental health disorders of children and adolescents (5).Mental health drugsThe field of modern psychopharmacology began in the 1930s with the availability of various psychoactive medications such as barbiturates, antihistamines, and psychostimulants (6). The seminal work of Bradley in 1937 identified Benzedrine (racemic mixture of levoamphetamine and dextroamphetamine) as a drug that improved the behavior of 30 children in Providence, Rhode Island, USA who had various emotional and behavioral problems (7). In the same year Molitch and Eccles conducted what may be the first placebo-controlled work in child psychiatry to show the positive effect of Benzadrine on 93 males labeled as juvenile delinquents (8).Chlorpromazine was introduced in 1950 as the first of many future antipsychotic medications to treat psychosis in adults.Also, in the 1950s, the
自从智人作为一个物种出现以来,人类的精神或情感问题可能就存在了(1)。历史上的医学治疗可以追溯到埃伯斯纸莎草(公元前1500年),上面列出了700多种不同来源的药物——动物、蔬菜、矿物质等(2)。中国和印度的学者在几千年的时间里制定了大量的药典,治疗各种疾病(3)。然而,古代哲学家亚里士多德(公元前384-322年),他对医学的力量持怀疑态度,正如他的观点所指出的:“……医生不能治愈人类,除非在偶然的情况下。”(4)区分儿童和青少年的医学和心理问题需要数千年的观察,因为大部分精力都花在成人的疾病上。医疗保健的进步最初通常以成人为目标,在过去一千年中逐渐考虑到儿童的健康。拉泽斯(穆罕默德·伊本·扎卡里亚·拉齐[公元865-925年])是古代波斯最著名的医生,他出色的观察和著作开创了儿科知识的诞生,他写了一本关于儿童疾病的书,与此同时,西方文明的知识在黑暗时代消失了。最终,西方的学者们从知识的深渊中走了出来,意大利萨莱诺的特罗图拉·普拉塔利乌斯(公元1050年)和托马斯·菲尔(公元1544年)分别撰写了关于儿童的教科书(《儿童书》)。Thomas Phaer是一名英国儿科医生、律师,也是第一本英语儿科书籍的作者;这篇具有里程碑意义的论文是第一本区分童年和成年这两个关键阶段的著作,为进一步研究童年问题奠定了基础。四个世纪后,随着1930年美国儿科学会的成立,儿童的医学问题终于得到了重视。美国儿童精神病学学会成立于1953年,目的是研究儿童的精神问题,《美国儿童和青少年精神病学学会杂志》于1962年创刊,记录儿童和青少年精神健康障碍方面的研究发现。精神健康药物现代精神药理学领域始于20世纪30年代,当时出现了各种精神药物,如巴比妥酸盐、抗组胺药、1937年,布拉德利的开创性工作确定了苯丙胺(左苯丙胺和右苯丙胺的外消旋混合物)是一种改善罗德岛普罗维登斯30名儿童行为的药物。同年,莫里奇和埃克尔斯在儿童精神病学领域进行了可能是第一次以安慰剂为对照的研究,表明苯丙胺对93名被标记为少年犯的男性有积极作用。氯丙嗪于1950年被引入,成为后来治疗成人精神病的许多抗精神病药物中的第一个。此外,在20世纪50年代,引入了两类抗抑郁药,一种单胺氧化酶抑制剂(异丙肼)和一种三环抗抑郁药(丙咪嗪)(9,10)。哌醋甲酯(MPH)于1959年由美国堪萨斯州的Knobel首次发现,在MPH于1957年首次上市后,该药物可改善患有“多动性和有机性”的儿童的行为(10)。锂、抗抑郁药和苯二氮卓类药物在1965年之前被投放到一般市场,然后精神药理学的使用被牢牢地放在处理成人精神障碍的成年精神病学家的设备中。虽然儿童精神药理学最早是由Bradley(1937)和Knobel(1959)的工作发展起来的,但治疗儿童和青少年精神障碍的药物的进一步发展在20世纪的大部分时间里基本上停止了,直到20世纪90年代。这种延迟是由多种因素共同造成的,包括人们认为心理治疗是治疗患有精神疾病的儿科患者的最佳方法,以及制药公司主要强调为患有精神疾病的成人开发药物。…
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引用次数: 2
Do young adults participate in surveys that 'go green'? Response rates to a web and mailed survey of weight-related health behaviors. 年轻人是否会参与“走向绿色”的调查?一项关于体重相关健康行为的网络和邮寄调查的回复率。
Nicole Larson, Dianne Neumark-Sztainer, Eileen M Harwood, Marla E Eisenberg, Melanie M Wall, Peter J Hannan

There is a paucity of research regarding the contextual factors that influence health behaviors to inform the development of programs and services for youth during the transition from adolescence to young adulthood. Researchers are thus in need of efficient strategies for surveying diverse populations of young adults. This study among a population-based sample of young adults aimed to 1) examine response to a mixed-mode survey design (web and mailed surveys) and 2) identify demographic correlates of response mode. Young adults who participated in previous study waves were invited to participate in the third wave of a 10-year longitudinal study (Project EAT-III: 2008-2009) examining factors associated with weight-related behaviors. Participants were mailed invitation letters providing the web address and a unique password for completing the survey. Nonresponders were mailed three reminder invitations; the third mailing included the paper form, and all other mailings included a postage-paid card for requesting the paper form. Most completed surveys (82.1% of n=2,287) were returned by respondents within the first four months of fielding prior to the mailing which included the paper form. Nearly all of these early responders (92.6% of n=1,878) and 86.5% of the full respondent sample (n=1,979 of 2,287) completed the web form. Response to the web versus mailed paper form of the survey was associated with age >25 years, higher socioeconomic status, current employment, student status, and having no children. The combination of web and mailed survey modes is an effective strategy for conducting data collection in demographically diverse, young adult populations.

关于影响健康行为的环境因素的研究很少,这些因素可以为青少年从青春期过渡到青年期的青少年提供规划和服务。因此,研究人员需要有效的策略来调查不同的年轻人。本研究在以人口为基础的年轻人样本中,旨在1)检查对混合模式调查设计(网络和邮寄调查)的反应,2)确定反应模式的人口统计学相关性。参加过前几次研究的年轻人被邀请参加第三次为期10年的纵向研究(EAT-III项目:2008-2009),研究与体重相关行为相关的因素。参与者收到了一封邀请函,其中提供了网站地址和完成调查的唯一密码。没有回应的人会收到三封提醒邀请函;第三次邮寄包括纸质表格,所有其他邮寄都包括一张邮资已付的卡片,用于索取纸质表格。大多数已完成的调查(82.1%,n=2,287)在邮寄前的前四个月内由受访者返回,其中包括纸质表格。几乎所有这些早期应答者(92.6%的n= 1878)和86.5%的完整应答者样本(n= 1979的2,287)完成了网络表格。对网络问卷的回应与邮寄纸质问卷的回应与年龄>25岁、较高的社会经济地位、当前就业、学生状况和没有孩子有关。网络和邮寄调查模式的结合是一种有效的策略,在人口统计学上多样化,年轻的成年人口进行数据收集。
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引用次数: 0
Early childhood lead exposure and exceptionality designations for students. 儿童早期铅暴露和学生的特殊指定。
Marie Lynn Miranda, Pamela Maxson, Dohyeong Kim

The achievement gap continues to be an important educational issue, with disadvantaged groups exhibiting poorer school performance. Recently, literature has shown that even very low levels of early lead exposure affect cognitive and academic performance. As individuals at the lower end of the socioeconomic spectrum are more likely to be exposed to lead, this exposure may be an important contributor to the achievement gap. In this paper, we explore whether early childhood blood lead levels are associated with membership in exceptionality designation groups. In addition, we examine the racial and socioeconomic composition of these exceptional groups. Data from the North Carolina Childhood Lead Poisoning Prevention Program surveillance registry were linked at the individual child level to educational outcomes available through the North Carolina Education Research Data Center. Designation into exceptionality groups was obtained from the end-of-grade (EOG) data. Both standard bivariate and multivariate analyses were employed. Bivariate analyses indicate that blood lead levels and reading EOG scores differ by exceptionality, as well as by race and enrollment in free/reduced lunch. Logistic regression confirmed the relationship between blood lead levels and likelihood of exceptionality. Contextual factors - enrollment in the free/reduced lunch program, race, and parental education - are also significant with regard to exceptionality. This study demonstrates that early childhood lead exposure significantly influences the likelihood of being designated exceptional. These results provide additional evidence that early childhood lead exposure is a significant explanator of the achievement gap.

成绩差距仍然是一个重要的教育问题,弱势群体在学校表现较差。最近,文献表明,即使是非常低水平的早期铅暴露也会影响认知和学习成绩。由于社会经济地位较低的人更有可能接触到铅,这种接触可能是成就差距的一个重要因素。在本文中,我们探讨是否早期儿童血铅水平与成员在特殊指定组相关。此外,我们还研究了这些特殊群体的种族和社会经济构成。来自北卡罗莱纳州儿童铅中毒预防项目监测登记的数据在儿童个体水平上与北卡罗莱纳州教育研究数据中心提供的教育成果相关联。从等级结束(EOG)数据中获得异常组的名称。采用标准双变量和多变量分析。双变量分析表明,血铅水平和阅读EOG分数因异常而异,也因种族和免费/减价午餐的登记而异。逻辑回归证实了血铅水平与异常可能性之间的关系。背景因素——参加免费/减少午餐计划、种族和父母教育——也对例外情况有重要影响。本研究表明,儿童早期铅暴露显著影响被指定为例外的可能性。这些结果提供了额外的证据,证明儿童早期铅暴露是成就差距的重要解释因素。
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引用次数: 0
Changes in Severity of Allergy and Anxiety Symptoms Are Positively Correlated in Patients with Recurrent Mood Disorders Who Are Exposed to Seasonal Peaks of Aeroallergens. 暴露于空气过敏原季节性高峰的复发性情绪障碍患者的过敏和焦虑症状的严重程度变化呈正相关。
Pub Date : 2009-02-01 DOI: 10.1016/J.JACI.2008.12.900
T. Postolache,, P. Langenberg, Sarah A. Zimmerman, M. Lapidus, Hirsh D. Komarow, J. S. McDonald, N. Furst, Natalya Dzhanashvili, Debra A. Scrandis, J. Bai, Bernadine Postolache, Joseph J. Soriano, B. Vittone, Alvaro Guzmán, J. Woo, J. Stiller, R. Hamilton, L. Tonelli
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引用次数: 14
Prepartum Depressive Symptoms Correlate Positively with C-Reactive Protein Levels and Negatively with Tryptophan Levels: A Preliminary Report. 预备期抑郁症状与c反应蛋白水平正相关,与色氨酸水平负相关:初步报告
Debra A Scrandis, Patricia Langenberg, Leonardo H Tonelli, Tehmina M Sheikh, Anita C Manogura, Laura A Alberico, Tracey Hermanstyne, Dietmar Fuchs, Hugh Mighty, Jeffrey D Hasday, Kalina Boteva, Teodor T Postolache

Prepartum and postpartum depression have negative, and sometimes devastating, effects on women and their families. As inflammatory processes are related to depression in general, we hypothesized that inflammatory perturbations, prepartum and postpartum, contribute to triggering and worsening of symptoms of peripartum depression. We conducted a longitudinal preliminary study on 27 women at high risk for developing postpartum depression measuring SIGH-SAD scores at three time points: 35-38 weeks gestation, 1-5 days postpartum, and 5-6 weeks postpartum. Serum C-reactive protein and interleukin-6, both markers of inflammation, as well as tryptophan, kynurenine, and the kynurenine/tryptophan ratio, as consequences of inflammation and pathophysiological steps towards depression, were measured at each time point. C-reactive protein levels were found to be positively related to atypical and total depression scores in the prepartum period and with atypical depression scores in the early postpartum period. Tryptophan was found to be negatively associated with total depression scores in the prepartum, as well. These findings warrant further investigation that could lead to novel interventions to decrease poor outcomes from peripartum depression.

产前和产后抑郁症对妇女及其家庭有负面影响,有时甚至是毁灭性的影响。由于炎症过程通常与抑郁症有关,我们假设产前和产后的炎症扰动会引发和恶化围产期抑郁症的症状。我们对27名产后抑郁症高危女性进行了一项纵向初步研究,测量了妊娠35-38周、产后1-5天和产后5-6周三个时间点的SIGH-SAD评分。在每个时间点测量血清C反应蛋白和白细胞介素-6,这两种炎症标志物,以及色氨酸、犬尿蛋白和犬尿蛋白/色氨酸比率,作为炎症和抑郁症病理生理步骤的后果。C反应蛋白水平与产前的非典型和总抑郁评分呈正相关,与产后早期的非典型抑郁评分呈正相关性。色氨酸也被发现与制剂中的总抑郁评分呈负相关。这些发现值得进一步研究,可能会导致新的干预措施,以减少围产期抑郁症的不良后果。
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引用次数: 0
Childhood Obesity and Depression: Connection between these Growing Problems in Growing Children. 儿童肥胖和抑郁:这些成长中的儿童日益严重的问题之间的联系。
Gloria M Reeves, Teodor T Postolache, Soren Snitker

Depression and obesity have been recognized as major public health issues in youths. Although they have traditionally been compartmentalized as separate physical and emotional health conditions, evidence suggests interactions and common pathways between them, implying that successful treatment should ideally target shared underlying mechanisms. The purpose of the present article is to review the pediatric diagnostic criteria for depression and obesity, highlight similarities in their clinical presentation, identify common pathways and underlying mechanisms, describe their developmental trajectories, and suggest areas for future study to guide development of innovative prevention and treatment initiatives.

抑郁和肥胖已被认为是青少年的主要公共健康问题。虽然它们传统上被划分为独立的身体和情绪健康状况,但有证据表明它们之间存在相互作用和共同途径,这意味着成功的治疗应该理想地针对共同的潜在机制。本文的目的是回顾抑郁症和肥胖症的儿科诊断标准,强调其临床表现的相似性,确定共同的途径和潜在机制,描述其发展轨迹,并提出未来研究的领域,以指导创新预防和治疗措施的发展。
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引用次数: 0
Ethnic Differences in Adolescent Suicide in the United States. 美国青少年自杀的种族差异。
Theodora Balis, Teodor T Postolache

Suicide is the third-leading cause of death for adolescents between 15 and 24 years of age in the United States and its rate has been increasing. Factors that contribute to rate of, risks for, or protection against depression and suicide may be different for people from cultures with different values and health beliefs. Although typically seen as affecting Caucasians more than other groups in the U.S., the rates of suicide among African Americans, Latinos, and others have been increasing. 87 studies were reviewed looking at rates for suicide/suicidal ideation, risk factors for suicide, protective factors/coping mechanisms, service delivery/barriers to care, and specific treatment or management of suicidal thoughts for adolescents from different ethnic groups in the U.S. The following ethnic groups in the U.S. were compared: African American, Latino, Asian American, Native American/Alaskan Native, and Hawaiian American. Although studies report conflicting rates, most studies still show an overall higher risk for suicidal behavior among Caucasian youth than any other group. Rates for suicidal behavior are growing for African American teens (perhaps more in boys), Latino teens (especially Latina girls), Asian American youth, Native American youth, Alaskan Native youth, and Hawaiian American youth. Details about these differences are discussed along with recommendations for clinicians working with youth at risk for suicide from minority cultures in the U.S.

自杀是美国 15-24 岁青少年的第三大死因,而且自杀率一直在上升。不同文化背景的人有着不同的价值观和健康观念,导致抑郁症和自杀率、风险或防护措施不同的因素也可能不同。在美国,虽然白种人的自杀率通常高于其他群体,但非裔美国人、拉美裔美国人和其他人的自杀率也在不断上升。我们对 87 项研究进行了回顾,这些研究涉及美国不同种族青少年的自杀率/自杀意念、自杀风险因素、保护因素/应对机制、服务提供/护理障碍以及自杀意念的具体治疗或管理:非裔美国人、拉丁裔美国人、亚裔美国人、原住民/阿拉斯加原住民以及夏威夷裔美国人。尽管研究报告的自杀率相互矛盾,但大多数研究仍然表明,高加索青少年的自杀行为风险总体上高于其他任何群体。非裔美国青少年(男孩可能更多)、拉丁裔青少年(尤其是拉丁裔女孩)、亚裔美国青少年、美国原住民青少年、阿拉斯加原住民青少年和夏威夷裔美国青少年的自杀行为发生率正在上升。本文讨论了这些差异的详细情况,并为从事美国少数民族文化青少年自杀风险工作的临床医生提出了建议。
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引用次数: 0
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International journal of child health and human development : IJCHD
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