Pub Date : 1942-07-01DOI: 10.1016/S0002-9610(42)90950-4
H. W. Meyerding, R. S. Clegg
{"title":"MODERN treatment of osteomyelitis.","authors":"H. W. Meyerding, R. S. Clegg","doi":"10.1016/S0002-9610(42)90950-4","DOIUrl":"https://doi.org/10.1016/S0002-9610(42)90950-4","url":null,"abstract":"","PeriodicalId":88089,"journal":{"name":"Physician's bulletin","volume":"49 1","pages":"163-7"},"PeriodicalIF":0.0,"publicationDate":"1942-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72868661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1942-02-01DOI: 10.1001/ARCHPEDI.1942.02010020010002
J. Lapin
Pnrophylaxis against diphtheria is universally recommended; prophylaxis against whooping cough is now generally accepted; and prophylaxis against tetanus has been found effective, although it has not been used routinely. The combined prophylaxis against two of the three diseases—diphtheria and tetanus—has been in use for several years.1This paper records my experience with the combined prophylaxis against the three diseases—diphtheria, tetanus and whooping cough. Theoretically, this triple immunization would present two advantages: first, possible adsorption of the toxoids and toxins by bacterial suspension, thus affording what Ramon2has called a larger "effective antigenic surface;" second, nonspecific enhancement of antigen production, termed by Ramon "antigenic synergy." As an example of antigenic enhancement produced by the mixture of a toxoid with a bacterial vaccine, the work of Schutze3is of interest. He immunized guinea pigs with mixtures of alum-precipitated diphtheria toxoid and whooping cough vaccine and reported the antigenic
{"title":"IMMUNIZATION of infants against diphtheria, tetanus, and whooping cough.","authors":"J. Lapin","doi":"10.1001/ARCHPEDI.1942.02010020010002","DOIUrl":"https://doi.org/10.1001/ARCHPEDI.1942.02010020010002","url":null,"abstract":"Pnrophylaxis against diphtheria is universally recommended; prophylaxis against whooping cough is now generally accepted; and prophylaxis against tetanus has been found effective, although it has not been used routinely. The combined prophylaxis against two of the three diseases—diphtheria and tetanus—has been in use for several years.1This paper records my experience with the combined prophylaxis against the three diseases—diphtheria, tetanus and whooping cough. Theoretically, this triple immunization would present two advantages: first, possible adsorption of the toxoids and toxins by bacterial suspension, thus affording what Ramon2has called a larger \"effective antigenic surface;\" second, nonspecific enhancement of antigen production, termed by Ramon \"antigenic synergy.\" As an example of antigenic enhancement produced by the mixture of a toxoid with a bacterial vaccine, the work of Schutze3is of interest. He immunized guinea pigs with mixtures of alum-precipitated diphtheria toxoid and whooping cough vaccine and reported the antigenic","PeriodicalId":88089,"journal":{"name":"Physician's bulletin","volume":"29 1","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"1942-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83315134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1941-11-08DOI: 10.1001/JAMA.1941.02820450023006
E. Rovenstine, H. Wertheim
"Therapeutic nerve block" is but one of the many ramifications of regional analgesia. The history of the introduction and development of perineural injections of analgesic and neurolytic agents for therapy coincides with that of similar types of injections to control the pain associated with surgical procedures. The use of surgical analgesic nerve blocks has eclipsed by far similar procedures employed to cure or alleviate pain or symptoms resulting from disease or injury. Coming into being, as it did, less than fifty-seven years ago, regional analgesia found a large number of enthusiastic surgical pioneers to explore its possibilities, exploit its application and evaluate it in surgical practice. Nerve block was discovered at the very dawn of modern abdominal surgery when the leaders in medicine were focusing the attention of the world on the blessings of the scalpel and were giving their best efforts toward developing the possibilities that anesthesia and antisepsis
{"title":"THERAPEUTIC nerve block.","authors":"E. Rovenstine, H. Wertheim","doi":"10.1001/JAMA.1941.02820450023006","DOIUrl":"https://doi.org/10.1001/JAMA.1941.02820450023006","url":null,"abstract":"\"Therapeutic nerve block\" is but one of the many ramifications of regional analgesia. The history of the introduction and development of perineural injections of analgesic and neurolytic agents for therapy coincides with that of similar types of injections to control the pain associated with surgical procedures. The use of surgical analgesic nerve blocks has eclipsed by far similar procedures employed to cure or alleviate pain or symptoms resulting from disease or injury. Coming into being, as it did, less than fifty-seven years ago, regional analgesia found a large number of enthusiastic surgical pioneers to explore its possibilities, exploit its application and evaluate it in surgical practice. Nerve block was discovered at the very dawn of modern abdominal surgery when the leaders in medicine were focusing the attention of the world on the blessings of the scalpel and were giving their best efforts toward developing the possibilities that anesthesia and antisepsis","PeriodicalId":88089,"journal":{"name":"Physician's bulletin","volume":"35 1","pages":"5-14"},"PeriodicalIF":0.0,"publicationDate":"1941-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89213187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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