Pub Date : 2023-06-22DOI: 10.1007/s11901-023-00605-8
Bassem Ibrahim, Dhanashree Tikhe, S. Bollipo
{"title":"The Role of Micronutrients in Chronic Liver Disease","authors":"Bassem Ibrahim, Dhanashree Tikhe, S. Bollipo","doi":"10.1007/s11901-023-00605-8","DOIUrl":"https://doi.org/10.1007/s11901-023-00605-8","url":null,"abstract":"","PeriodicalId":88466,"journal":{"name":"Current hepatitis reports","volume":"22 1","pages":"216 - 220"},"PeriodicalIF":0.0,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45145400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-09DOI: 10.1007/s11901-023-00602-x
Madeleine G Haff, A. Mohanty
{"title":"Role of Nutrition in Preventing Liver Disease","authors":"Madeleine G Haff, A. Mohanty","doi":"10.1007/s11901-023-00602-x","DOIUrl":"https://doi.org/10.1007/s11901-023-00602-x","url":null,"abstract":"","PeriodicalId":88466,"journal":{"name":"Current hepatitis reports","volume":"22 1","pages":"74 - 81"},"PeriodicalIF":0.0,"publicationDate":"2023-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45930561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01Epub Date: 2023-02-20DOI: 10.1007/s11901-023-00600-z
Mohamed A Elfeki, Ashwani K Singal, Patrick S Kamath
Purpose: Non-selective beta blockers remain pharmacotherapy of choice for prevention of first episode of variceal bleeding (primary prevention) and for prevention of its recurrence after initial hemostasis (secondary prophylaxis). This review will update the current and emerging pharmacological therapies for portal hypertension.
Recent findings: Data have emerged on carvedilol in preventing hepatic decompensation and improving patient survival among patients with clinically significant portal hypertension. Because measurement of WHVP is invasive and not feasible in routine practice, non-invasive tests with liver stiffness measurement in combination with platelet count may be accurate in identifying clinically significant portal hypertension.
Summary: Carvedilol is more effective in reducing portal pressure compared to nadolol or propranolol. Its use has expanded to reduce risk of hepatic decompensation among patients with CSPH, which can be identified non-invasively using liver stiffness and platelet count. Studies are needed on non-invasive biomarkers to guide and optimize pharmacological treatment of portal hypertension.
{"title":"Pharmacotherapies for Portal Hypertension: Current Status and Expanding Indications.","authors":"Mohamed A Elfeki, Ashwani K Singal, Patrick S Kamath","doi":"10.1007/s11901-023-00600-z","DOIUrl":"10.1007/s11901-023-00600-z","url":null,"abstract":"<p><strong>Purpose: </strong>Non-selective beta blockers remain pharmacotherapy of choice for prevention of first episode of variceal bleeding (primary prevention) and for prevention of its recurrence after initial hemostasis (secondary prophylaxis). This review will update the current and emerging pharmacological therapies for portal hypertension.</p><p><strong>Recent findings: </strong>Data have emerged on carvedilol in preventing hepatic decompensation and improving patient survival among patients with clinically significant portal hypertension. Because measurement of WHVP is invasive and not feasible in routine practice, non-invasive tests with liver stiffness measurement in combination with platelet count may be accurate in identifying clinically significant portal hypertension.</p><p><strong>Summary: </strong>Carvedilol is more effective in reducing portal pressure compared to nadolol or propranolol. Its use has expanded to reduce risk of hepatic decompensation among patients with CSPH, which can be identified non-invasively using liver stiffness and platelet count. Studies are needed on non-invasive biomarkers to guide and optimize pharmacological treatment of portal hypertension.</p>","PeriodicalId":88466,"journal":{"name":"Current hepatitis reports","volume":"22 1","pages":"44-50"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10723787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45530842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.1007/s11901-023-00595-7
Emily Truong, C. Han, M. Muthiah, M. Noureddin
{"title":"Risk Stratification for Hepatocellular Carcinoma in Patients with Non-alcoholic Fatty Liver Disease","authors":"Emily Truong, C. Han, M. Muthiah, M. Noureddin","doi":"10.1007/s11901-023-00595-7","DOIUrl":"https://doi.org/10.1007/s11901-023-00595-7","url":null,"abstract":"","PeriodicalId":88466,"journal":{"name":"Current hepatitis reports","volume":"22 1","pages":"1 - 8"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44425309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-06DOI: 10.1007/s11901-023-00597-5
C. Vashishtha, S. Sarin
{"title":"Management of Gastric and Ectopic Varices","authors":"C. Vashishtha, S. Sarin","doi":"10.1007/s11901-023-00597-5","DOIUrl":"https://doi.org/10.1007/s11901-023-00597-5","url":null,"abstract":"","PeriodicalId":88466,"journal":{"name":"Current hepatitis reports","volume":"22 1","pages":"33 - 43"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48391153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-24eCollection Date: 2022-01-01DOI: 10.3389/fopht.2022.970580
Dana Al-Bader, Alya Hasan, Raed Behbehani
Sellar mases can cause a variety of neuro-ophthalmic manifestations, including compressive optic neuropathy, chiasmal syndrome, and ophthalmoplegia due to cranial nerve palsy. Diagnosis involves a thorough history, neuro-ophthalmic examination, and ancillary tests and investigations. Visual field testing is critical in diagnosing and localizing the lesion and determining the extent of visual field loss. Appropriate neuro-imaging is essential in characterizing and localizing the lesion. Neuro-ophthalmologic assessment include meticulous clinical examination and ancillary tests including,visual field testing, which is useful in localizing the lesion, and optical coherence tomography, which is helpful in assessing the degree of axonal and neuronal loss and predicting the visual outcome. Treatment requires a multidisciplinary approach by different specialties, including radiologists, neuro-ophthalmologists, and neurosurgeons. The two primary treatment modalities for these tumors are surgery and radiation therapy. We review the main types of sellar lesions, their neuro-ophthalmologic evaluation, and treatment options.
{"title":"Sellar masses: diagnosis and treatment.","authors":"Dana Al-Bader, Alya Hasan, Raed Behbehani","doi":"10.3389/fopht.2022.970580","DOIUrl":"10.3389/fopht.2022.970580","url":null,"abstract":"<p><p>Sellar mases can cause a variety of neuro-ophthalmic manifestations, including compressive optic neuropathy, chiasmal syndrome, and ophthalmoplegia due to cranial nerve palsy. Diagnosis involves a thorough history, neuro-ophthalmic examination, and ancillary tests and investigations. Visual field testing is critical in diagnosing and localizing the lesion and determining the extent of visual field loss. Appropriate neuro-imaging is essential in characterizing and localizing the lesion. Neuro-ophthalmologic assessment include meticulous clinical examination and ancillary tests including,visual field testing, which is useful in localizing the lesion, and optical coherence tomography, which is helpful in assessing the degree of axonal and neuronal loss and predicting the visual outcome. Treatment requires a multidisciplinary approach by different specialties, including radiologists, neuro-ophthalmologists, and neurosurgeons. The two primary treatment modalities for these tumors are surgery and radiation therapy. We review the main types of sellar lesions, their neuro-ophthalmologic evaluation, and treatment options.</p>","PeriodicalId":88466,"journal":{"name":"Current hepatitis reports","volume":"14 1","pages":"970580"},"PeriodicalIF":0.0,"publicationDate":"2022-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74794241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}