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Clostridium Tertium Isolated From a Necrotizing Soft Tissue Infection in a Diabetic but Otherwise Nonimmunocompromised Patient 从糖尿病患者的坏死性软组织感染中分离出的Tertium梭菌
Pub Date : 2011-06-01 DOI: 10.1016/j.jcws.2011.09.002
Elizabeth A. Steensma MD, Christian W. Ertl MD, FACS, FACCWS, Leandra H. Burke BS

Clostridium tertium has historically been regarded as nonpathogenic, and its implication as the primary microbe in infectious etiologies remains unclear. Although there have been several reports of C tertium isolated from blood, tissue, and other specimens, largely this population has consisted of patients with neutropenia, hematologic malignancies, or gastrointestinal disorders. Here we describe a case of a 39-year-old nonimmunocompromised man with a history of type 1 diabetes mellitus and intravenous drug use who presented to our institution with a necrotizing soft tissue infection involving his right upper extremity. The infection had developed after the patient had injected methamphetamines. At surgery, tissue was obtained for Gram stain and culture, yielding C tertium, after an initial misidentification as Lactobacillus species. After undergoing extensive surgical debridement and treatment with an appropriate antibiotic regimen, the patient was able to be discharged home with retained function of his extremity. Although not common, infections involving C tertium can produce severe, potentially life- and limb-threatening disease processes, which may require aggressive therapy even in the nonimmunocompromised patient.

从历史上看,tertium梭状芽孢杆菌被认为是非致病性的,其作为感染性病原学的主要微生物的含义尚不清楚。虽然有几篇报道从血液、组织和其他标本中分离出C - tertium,但这一人群主要是中性粒细胞减少症、血液恶性肿瘤或胃肠道疾病患者。在这里,我们描述了一个39岁的非免疫功能低下的男性,有1型糖尿病和静脉吸毒的历史,他向我们的机构提出了坏死性软组织感染,涉及他的右上肢。感染是在患者注射甲基苯丙胺后发生的。在手术中,获得组织进行革兰氏染色和培养,在最初被误认为乳杆菌物种后,产生C tertium。经过广泛的手术清创和适当的抗生素治疗后,患者得以出院回家,其肢体功能得以保留。虽然不常见,但涉及C - tertium的感染可产生严重的,可能危及生命和肢体的疾病过程,即使在非免疫功能低下的患者中,也可能需要积极治疗。
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引用次数: 7
Novel Wound Healing Powder Formulation for the Treatment of Venous Leg Ulcers 治疗腿部静脉性溃疡的新型伤口愈合粉配方
Pub Date : 2011-06-01 DOI: 10.1016/j.jcws.2011.09.004
Angela V. Ghatnekar PhD , Tuan Elstrom BS , Gautam S. Ghatnekar PhD , Teresa Kelechi PhD

Chronic venous disorders are common in the Western world. The current treatment of venous leg ulcers is unsatisfactory despite the availability of well-documented standards of care. Patients today are interested in alternative approaches to modern medicine. We have developed a wound-healing powder containing natural ingredients with absorptive, aromatic, antiseptic, and anti-inflammatory synergistic properties. This report describes 3 cases that were successfully treated with the powder, demonstrating the potential of herbal remedies in the clinical treatment of venous leg ulcers.

慢性静脉疾病在西方世界很常见。尽管有完善的护理标准,但目前下肢静脉性溃疡的治疗并不令人满意。今天的病人对现代医学的替代方法很感兴趣。我们开发了一种含有天然成分的伤口愈合粉,具有吸收、芳香、防腐和抗炎的协同作用。本报告描述了3例用该粉末成功治疗的病例,展示了草药在静脉性腿部溃疡临床治疗中的潜力。
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引用次数: 7
Ace Your Certification Exam 通过认证考试
Pub Date : 2011-03-01 DOI: 10.1016/j.jcws.2011.05.001
Jayesh Shah MD, CWS, FACCWS, FAPWCA, UHM, FACHM

Dr Jayesh Shah authors this quarterly column, consisting of 5 questions with explanations, to help you practice for your exam.

Jayesh Shah博士撰写了这个季度专栏,包括5个问题和解释,以帮助你练习你的考试。
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引用次数: 0
Letter from the Chair 主席的信
Pub Date : 2011-03-01 DOI: 10.1016/j.jcws.2011.05.004
Aimée D. Garcia MD, CWS, FACCWS
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引用次数: 0
The Significance of Introducing Permanent Assignments for Nursing Assistants at a Long-Term Care Setting on the Incidence Rate of Facility-Acquired Pressure Ulcers Among Elderly Patients 在长期护理机构中引入护理助理的长期任务对老年患者设施获得性压疮发生率的意义
Pub Date : 2011-03-01 DOI: 10.1016/j.jcws.2011.03.002
Erlynda Mangaco-Borja MSN, DSD RNC

Pressure ulcer prevalence remains a major health concern in long-term care facilities. The treatment of these pressure ulcers causes a financial drain on health care resources and adds potential costs for the family of the institutionalized elderly, according to the Agency for Healthcare Research and Quality. The prevention of pressure ulcer development continues to be an essential objective of caregivers for elderly people. This study demonstrated a correlation between the permanent assignment of nursing assistants and the prevention of pressure ulcers among the elderly in a nursing home.

压疮的流行仍然是长期护理机构的一个主要健康问题。据医疗保健研究和质量机构称,这些压疮的治疗导致医疗保健资源的财政消耗,并增加了养老院老年人家庭的潜在成本。预防压疮的发展仍然是老年人护理人员的一个重要目标。本研究证明了护理助理的长期分配与养老院老年人压疮预防之间的相关性。
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引用次数: 2
Silver Toxicity With the Use of Silver-Impregnated Dressing and Wound Vacuum-Assisted Closure in an Immunocompromised Patient 免疫功能低下患者使用银浸渍敷料和真空辅助缝合伤口的银毒性
Pub Date : 2011-03-01 DOI: 10.1016/j.jcws.2011.05.002
Cabrini A. LaRiviere MD, Adam B. Goldin MD, MPH, Jeffrey Avansino MD

Silver-containing topical agents are used to help prevent infectious complications in wound therapy. Toxicity from topical silver agent exposure was initially reported in 1975 and was clinically characterized by granulocytopenia. Currently, the data regarding potential toxicity associated with silver-impregnated devices are limited. A 23-year-old patient receiving chemotherapy for acute lymphoblastic leukemia presented with necrotizing fasciitis of the abdominal wall and scrotum from a Crohn disease–related psoas-enteric fistula. Surgical debridement of the soft-tissue and abdominal musculature was performed to the peritoneum. Silver-containing foam sponges and wound vacuum-assisted closure were applied directly to the peritoneum 2 weeks after initial debridement. Subsequently, the patient developed leukopenia, and workup revealed the serum silver level was 4 times normal level. Silver-impregnated sponges were discontinued and silver-free sponges and wound vacuum-assisted closure therapy resumed, followed by leukopenia resolution. Silver toxicity associated with routine application of silver-impregnated sponges has not been previously reported.

在伤口治疗中,含银的局部药物被用来帮助预防感染并发症。局部银剂暴露的毒性最初是在1975年报道的,其临床特征是粒细胞减少。目前,关于与银浸渍装置相关的潜在毒性的数据有限。一例23岁的急性淋巴细胞白血病患者,因克罗恩病引起的腰肠瘘而接受化疗,并发腹壁和阴囊坏死性筋膜炎。对腹膜进行软组织和腹部肌肉组织的手术清创。首次清创2周后,将含银泡沫海绵和伤口真空辅助闭合直接应用于腹膜。随后,患者出现白细胞减少,检查发现血清银水平是正常水平的4倍。停止使用浸银海绵,恢复无银海绵和伤口真空辅助闭合治疗,随后白细胞减少。与常规应用银浸渍海绵相关的银毒性先前未见报道。
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引用次数: 10
Phase Angle, an Alternative Physiological Tool to Assess Wound Treatment in Chronic Nonhealing Wounds 相位角:评估慢性不愈合伤口治疗的另一种生理工具
Pub Date : 2011-03-01 DOI: 10.1016/j.jcws.2011.06.001
Michael F. Moore MD, FACS, CWS, FACCWS , Nanci Dobson RN, CWCA , Lisa Castelllino RN, CWCA , Susan Kapp BSN

Background

This exploratory study was conducted in an effort to demonstrate that bioelectrical impedance analysis (BIA) phase angle measurement is a novel tool for monitoring the effectiveness of a wound care regimen at a regional level and is valuable in comparing that status with the overall metabolic health of the patient. Isolating and measuring the extent to which nutritional supplementation contributes to the healing process is difficult and confounded by the many treatment modalities patients undergo.

Objective

The authors conducted a limited exploratory study to determine whether regional phase angle measurements accurately reflected the status of chronic nonhealing wounds. This information would potentially provide the ability to quantitatively evaluate of the role of nutritional supplementation in wounds of varying etiologies by comparing regional BIA phase angle measurement with overall BIA phase angle measurement.

Methods

Eleven patients with wounds of varying etiologies were selected to participate. Each patient underwent a treatment regimen specific to his or her condition, and all patients were given JUVEN® nutritional supplement.

Results and Conclusion

In all patients, the BIA phase angle measurement mirrored the health of the wound and provided an accurate tool for assessing the regional tissue health, a valuable insight in measuring the effectiveness of a systemic treatment.

本探索性研究旨在证明生物电阻抗分析(BIA)相角测量是一种监测区域伤口护理方案有效性的新工具,并且在将该状态与患者的整体代谢健康状况进行比较时具有价值。分离和测量营养补充对愈合过程的贡献程度是困难的,并且由于患者接受的许多治疗方式而混淆。目的通过一项有限的探索性研究来确定局部相角测量是否能准确反映慢性未愈合伤口的状态。通过比较局部BIA相位角测量和整体BIA相位角测量,这一信息可能会提供定量评估营养补充在不同病因伤口中的作用的能力。方法选取不同病因的创伤患者作为研究对象。每位患者都接受了针对其病情的治疗方案,所有患者均给予JUVEN®营养补充剂。结果与结论在所有患者中,BIA相位角测量反映了伤口的健康状况,为评估区域组织健康提供了准确的工具,为衡量全身治疗的有效性提供了有价值的见解。
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引用次数: 8
Efficiency of Microbial Cellulose Dressing in Partial-Thickness Burn Wounds 微生物纤维素敷料在部分厚度烧伤创面中的应用效果
Pub Date : 2011-03-01 DOI: 10.1016/j.jcws.2011.04.001
Pornprom Muangman MD, Supaporn Opasanon MD, Supaparn Suwanchot RN, Orapin Thangthed RN

Microbial cellulose is a natural polymer that can hold a quantity of water without any disconformities. Therefore, it is proposed for use as wound dressing material. We report a case of 28% total body surface area partial-thickness flame burn: approximately 4.5% superficial partial-thickness burns on anterior face and 23.5% combined superficial and deep partial-thickness burns on both upper arms and anterior trunk. A microbial cellulose dressing, Nanocell (Thai Nano Cellulose Co Ltd, Bangkok, Thailand), was applied to the face wound only once, without any further dressing change. Progress of healing, until full epithelialization on the face, was observed for 2 weeks. During the treatment period, the patient did not show any irritation or allergic reaction to this new dressing, and wound swab culture showed no evidence of bacteria presence. This innovative material can be an alternative dressing for superficial partial-thickness burn wounds.

微生物纤维素是一种天然聚合物,可以保持一定数量的水而没有任何不一致。因此,建议作为伤口敷料使用。我们报告了一例28%的体表面积部分厚度的火焰烧伤:大约4.5%的表面部分厚度烧伤在前面部和23.5%的上臂和前躯干的表面和深度部分厚度烧伤合并。一种微生物纤维素敷料,纳米细胞(泰国纳米纤维素有限公司,曼谷,泰国),只应用于面部伤口一次,没有任何进一步的敷料更换。观察愈合进展,直至面部完全上皮化2周。在治疗期间,患者对这种新敷料没有任何刺激或过敏反应,伤口拭子培养也没有发现细菌存在的证据。这种创新材料可作为浅表部分厚度烧伤创面的替代敷料。
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引用次数: 59
Ace Your Certification Exam 通过认证考试
Pub Date : 2010-12-01 DOI: 10.1016/j.jcws.2011.02.004
Jayesh Shah MD, CWS, FACCWS, FAPWCA, UHM, FACHM

Dr Jayesh Shah authors this quarterly column, consisting of 4 questions with explanations, to help you practice for your exam.

Jayesh Shah博士撰写了这个季度专栏,包括4个问题和解释,以帮助你练习你的考试。
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引用次数: 0
Off-Loading Practices for the Wounded Foot: Concepts and Choices 受伤脚的卸载练习:概念和选择
Pub Date : 2010-12-01 DOI: 10.1016/j.jcws.2011.02.001
Donald E. Mrdjenovich DPM, CWS, FACCWS

A wound practitioner’s best-laid plan of care and strategy for healing an ulcerated foot is doomed to fail without a properly conceived approach based on sound off-loading principles. Wound healing that has stalled despite best-practice techniques may require reevaluation of off-loading choices. This is particularly true in the patient with abnormal foot pathologies. Special considerations are certainly required with neuropathic ulcers; however, any wound on a weight-bearing surface of the foot requires proper off-loading. This discussion explores the basic biomechanical and pathomechanical concepts that modify and influence ambulation and gait patterns. Integration of these concepts into the choices for off-loading to deter pathologic influences will alert the reader of precautionary measures and other factors for consideration. The aim of this column is to provide both an adequate working knowledge of the available off-loading devices and the necessary tools and concepts needed to stimulate wise decision protocols for wound management and healing.

一个伤口医生最好的护理计划和策略,愈合溃疡的脚是注定要失败的,没有一个正确的构思方法,基于合理的卸载原则。尽管采用了最佳实践技术,但伤口愈合仍停滞不前,可能需要重新评估卸载选择。对于有异常足部病变的患者尤其如此。神经性溃疡当然需要特别注意;然而,脚部负重表面的任何伤口都需要适当的卸载。本讨论探讨了基本的生物力学和病理力学概念,这些概念可以改变和影响行走和步态模式。将这些概念整合到卸载的选择中,以阻止病理影响,将提醒读者采取预防措施和其他考虑因素。本专栏的目的是提供一个充分的工作知识,可用的卸载设备和必要的工具和概念,以刺激明智的决策协议,伤口管理和愈合。
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引用次数: 9
期刊
The journal of the American College of Certified Wound Specialists
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