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Risk of cardiovascular malformations after exposure to paroxetine in pregnancy: meta-analysis 妊娠期暴露于帕罗西汀后心血管畸形的风险:荟萃分析
Pub Date : 2013-06-01 DOI: 10.1192/PB.BP.111.035915
N. Painuly, Ritu Painuly, R. Heun, P. Sharan
Sciences Citation Index (SSCI), King’s Fund, DH-Data, CINAHL, Allied and Complementary Medicine Database (AMED) and British Nursing Index (BNI). Combinations of the terms ‘SSRI’, ‘selective serotonin reuptake inhibitor(s)’, ‘SRI’, ‘serotonin reuptake inhibitors’, ‘paroxetine’, ‘pregnancy’, ‘congenital malformation(s)’, ‘congenital defect(s)’, ‘cardiovascular malformation(s)’, ‘cardiac defect(s)’, ‘cardiovascular defect(s)’, ‘fetal malformation(s)’ and ‘fetal anomalies’ were used for the search. The search was restricted to articles published in English but there was no exclusion on the basis of country, ethical approval, etc. No grey literature was searched for this review. Each abstract/title and article was scrutinised by two of the authors (N.P. and R.P.) and the differences between them were resolved by consensus. Relevant articles were hand-searched for cross-references. The GlaxoSmithKline website was searched for recent data on paroxetine. To exclude repetitive data-sets, only the study with the most updated data was taken up for analysis. A repeat data search was done in August 2012, after the first review of this article, and results were updated.
科学引文索引(SSCI),国王基金,DH-Data, CINAHL,联合和补充医学数据库(AMED)和英国护理指数(BNI)。“选择性血清素再摄取抑制剂”、“选择性血清素再摄取抑制剂”、“SRI”、“血清素再摄取抑制剂”、“帕罗西汀”、“妊娠”、“先天性畸形”、“先天性缺陷”、“心血管畸形”、“心脏缺陷”、“心血管缺陷”、“胎儿畸形”和“胎儿异常”等术语的组合用于搜索。检索仅限于以英文发表的文章,但没有基于国家、伦理批准等因素进行排除。本综述未检索灰色文献。每个摘要/标题和文章都由两位作者(N.P.和R.P.)仔细审查,他们之间的差异通过共识来解决。手工检索相关文章以查找交叉参考。在葛兰素史克公司的网站上搜索帕罗西汀的最新数据。为了排除重复的数据集,只采用最新数据的研究进行分析。2012年8月,在对本文进行第一次审查后,进行了重复的数据检索,并更新了结果。
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引用次数: 9
Schema Therapy in Practice: An Introductory Guide to the Schema Mode Approach By Arnoud Arntz, Gitta Jacob, Wiley-Blackwell, 2013, £32.99, pb, 276 pp. ISBN: 9781119962861 实践中的图式治疗:图式模式方法入门指南,作者:Arnoud Arntz, Gitta Jacob, Wiley-Blackwell, 2013,£32.99,pb, 276 pp. ISBN: 9781119962861
Pub Date : 2013-06-01 DOI: 10.1192/PB.BP.112.042234
Lawrence Martean
Schema Therapy in Practice: An Introductory Guide to the Schema Mode Approach By Arnoud Arntz, Gitta Jacob Wiley-Blackwell, 2013, £32.99, pb, 276 pp. ISBN: 9781119962861 The continued proliferation of ‘branded’ psychotherapies can induce cynical beliefs that these are simply products of old
图式疗法的实践:图式模式方法的导论作者:Arnoud Arntz, Gitta Jacob willey - blackwell, 2013,£32.99,pb, 276 pp. ISBN: 9781119962861“品牌”心理疗法的持续扩散可能会引发愤世嫉俗的信念,认为这些只是旧的产品
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引用次数: 0
Psychiatrists' access to electronic laboratory results 精神科医生获得电子实验室结果的权利
Pub Date : 2013-05-01 DOI: 10.1192/PB.BP.112.040543
M. Skelton, S. Thacker, A. Forbes-Haley, Mahendra Kumar, E. Holliday
Aims and method A completed audit cycle, consisting of email surveys of all psychiatrists and a review of acute trust information technology registers was undertaken in Derbyshire Healthcare NHS Foundation Trust, to assess whether psychiatrists could access electronic laboratory results from the neighbouring acute trust laboratory. This was replicated in Nottinghamshire Healthcare NHS Trust, with an initial audit; plans were then implemented to increase access. Results In Derbyshire, 14% of psychiatrists could access electronic results initially, with limited ward access. By re-audit, all wards had access, and 28% used those systems. The later initial audit in Nottinghamshire Healthcare Trust revealed 6% access. Clinical implications Benefits of electronic results include clinical (faster decisions, safer monitoring, prompt detection of acute problems); efficiency savings (less wasted time telephoning); and other (improved relationships with general practitioners and laboratories, reduced marginalisation of patients with mental illness and professionals). There may be considerable clinical and efficiency savings for trusts.
目的和方法在德比郡医疗保健NHS基金会信托基金进行了一个完整的审计周期,包括对所有精神科医生的电子邮件调查和对急性信托信息技术登记册的审查,以评估精神科医生是否可以从邻近的急性信托实验室获取电子实验室结果。这在诺丁汉郡医疗保健NHS信托基金中得到了复制,并进行了初步审计;然后实施了增加访问的计划。结果在德比郡,14%的精神科医生最初可以访问电子结果,病房访问受限。通过重新审核,所有病房都有访问权限,28%的病房使用了这些系统。后来对诺丁汉郡医疗信托基金的初步审计显示,有6%的人访问了该基金。电子结果的好处包括临床(更快的决策,更安全的监测,及时发现急性问题);节省效率(减少浪费在打电话上的时间);以及其他(改善与全科医生和实验室的关系,减少精神疾病患者和专业人士的边缘化)。这可能会为信托机构节省相当多的临床费用和效率。
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引用次数: 0
The Psychedelic Renaissance: Reassessing the Role of Psychedelic Drugs in 21st Century Psychiatry and Society 迷幻药的复兴:重新评估迷幻药在21世纪精神病学和社会中的作用
Pub Date : 2013-05-01 DOI: 10.1192/pb.bp.112.042275
S. Kohli
The Psychedelic Renaissance: Reassessing the Role of Psychedelic Drugs in 21st Century Psychiatry and Society Ben Sessa Muswell Hill Press, 2012, £16.95, pb, 240 pp. ISBN: 9781908995001 Throughout the period of training and in clinical practice, there is a tendency to develop a prejudiced view
《迷幻药的复兴:重新评估迷幻药在21世纪精神病学和社会中的作用》Ben Sessa Muswell Hill出版社,2012,16.95英镑,pb, 240页。ISBN: 9781908995001在整个培训期间和在临床实践中,有一种发展偏见观点的趋势
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引用次数: 48
Drug information update: paliperidone palmitate for schizophrenia 药物信息更新:棕榈酸帕利哌酮治疗精神分裂症
Pub Date : 2013-05-01 DOI: 10.1192/PB.BP.113.042739
Abraham M. Nussbaum, T. Stroup
Aims and method To review the evidence for the use of paliperidone palmitate for people with schizophrenia and schizophrenia-like illnesses. We searched the Cochrane Schizophrenia Group Specialised Register and contacted the manufacturer of paliperidone palmitate, the US Food and Drug Administration, and the authors of papers that reported study results. Results Based on the evidence from five short-term, placebo-controlled studies, paliperidone palmitate is efficacious as an antipsychotic. Its adverse effects are similar to those of the closely related compounds paliperidone and risperidone. Extrapyramidal side-effects, weight gain and tachycardia are more common with paliperidone palmitate than placebo. Paliperidone palmitate was associated with substantial increases in serum prolactin but not with increased sexual side-effects in these studies. In two studies paliperidone palmitate was similar to depot risperidone. Clinical implications Paliperidone palmitate is an effective antipsychotic whose optimal dose appears to be between 39 and 234 mg every 4 weeks. We have no data assessing its long-term effectiveness or comparing it with any long-acting injected antipsychotic other than depot risperidone.
目的和方法回顾帕利哌酮棕榈酸酯治疗精神分裂症及精神分裂症样疾病的证据。我们检索了Cochrane精神分裂症组专门注册,并联系了帕利哌酮棕榈酸酯制造商、美国食品和药物管理局以及报告研究结果的论文作者。结果根据五项短期安慰剂对照研究的证据,棕榈酸帕利哌酮作为抗精神病药物是有效的。其不良反应与密切相关的化合物帕利培酮和利培酮相似。帕利哌酮的锥体外系副作用、体重增加和心动过速比安慰剂更常见。在这些研究中,棕榈酸帕利哌酮与血清催乳素的大量增加有关,但与性副作用的增加无关。在两项研究中,棕榈酸帕利哌酮与储存利培酮相似。临床意义棕榈酸帕利哌酮是一种有效的抗精神病药物,其最佳剂量为每4周39 - 234毫克。我们没有评估其长期有效性的数据,也没有将其与除depot利培酮以外的任何长效注射抗精神病药物进行比较。
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引用次数: 3
Mental Health Act 1983: use of urgent treatment in clinical practice 1983年《精神卫生法》:在临床实践中使用紧急治疗
Pub Date : 2013-05-01 DOI: 10.1192/PB.BP.112.038414
R. Yadav, A. Zigmond
Aims and method To understand circumstances in which urgent treatment provisions are used in clinical practice, by means of a retrospective study. A list of patients to whom Sections 62, 64B and 64G of the Mental Health Act 1983 were applied during the 1-year study period was obtained from the information technology department. Case notes were traced for detailed information on the circumstances of use of these provisions.Results The most common reason for urgent treatment was to continue the established treatment plan rather than to start a new treatment (45% Section 62, 84% Section 64). The urgent treatment provisions were most commonly used because of a delay in examination by a second opinion appointed doctor in 45% cases for Section 62 and 84% cases for Sections 64B and 64G.Clinical implications This is probably unlawful use of the urgent treatment provisions.
目的和方法通过回顾性研究了解临床实践中使用紧急治疗措施的情况。在为期一年的研究期间,从信息技术部门获得了1983年《精神卫生法》第62、64B和64G条适用的患者名单。追查了案件记录,以获得关于使用这些规定的情况的详细资料。结果紧急治疗最常见的原因是继续现有治疗方案,而不是开始新的治疗(62组占45%,64组占84%)。紧急治疗条款最常被使用,因为第62条45%的病例和第64B和64G条84%的病例延误了第二意见指定医生的检查。这可能是非法使用紧急治疗规定。
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引用次数: 1
From DSM-IV to DSM-5: an interim report from a cultural psychiatry perspective 从DSM-IV到DSM-5:文化精神病学视角的中期报告
Pub Date : 2013-05-01 DOI: 10.1192/PB.BP.112.040998
N. Aggarwal
In July 2012, the American Psychiatric Association (APA) closed its final commenting period on draft criteria for the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), slated for publication in May 2013. DSM-5 raises familiar questions about the cultural assumptions of proposed diagnoses, the scientific evidence base of these criteria and their validity in international settings. I review these issues since the publication of DSM-IV. I assess the cultural validity of DSM-5 and suggest areas of improvement.
2012年7月,美国精神病学协会(APA)结束了对第五版《精神疾病诊断与统计手册》(DSM-5)标准草案的最后评议期,该手册计划于2013年5月出版。DSM-5提出了关于拟议诊断的文化假设、这些标准的科学证据基础及其在国际环境中的有效性的熟悉问题。自DSM-IV出版以来,我回顾了这些问题。我评估了DSM-5的文化有效性,并提出了改进的领域。
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引用次数: 6
Psychology in the Bathroom 浴室里的心理学
Pub Date : 2013-05-01 DOI: 10.1192/PB.BP.112.041426
Stephen Ginn
Psychology in the Bathroom By Nick Haslam Palgrave Macmillan, 2012, £50.00, hb, 184 pp. ISBN: 9780230368248 With its centrality to psychoanalytic thought, excretion was once essential to the understanding of human motivation and personality. No longer, writes Professor Nick Haslam, author of
《洗手间里的心理学》作者:尼克·哈斯拉姆·帕尔格雷夫·麦克米伦,2012年,50英镑,hb, 184页。ISBN: 9780230368248由于其在精神分析思想中的核心地位,排泄曾经是理解人类动机和个性的必要条件。《。》一书的作者尼克·哈斯拉姆教授写道,不再是这样了
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引用次数: 0
Cyberbullying and its impact on young people’s emotional health and well-being 网络欺凌及其对年轻人情绪健康和福祉的影响
Pub Date : 2013-05-01 DOI: 10.1192/PB.BP.112.040840
H. Cowie
Aims and method The upsurge of cyberbullying is a frequent cause of emotional disturbance in children and young people. The situation is complicated by the fact that these interpersonal safety issues are actually generated by the peer group and in contexts that are difficult for adults to control. This article examines the effectiveness of common responses to cyberbullying. Results Whatever the value of technological tools for tackling cyberbullying, we cannot avoid the fact that this is an interpersonal problem grounded in a social context. Clinical implications Practitioners should build on existing knowledge about preventing and reducing face-to-face bullying while taking account of the distinctive nature of cyberbullying. Furthermore, it is essential to take account of the values that young people are learning in society and at school.
网络欺凌的激增是儿童和青少年情绪困扰的常见原因。这些人际安全问题实际上是由同龄人群体产生的,而且是在成年人难以控制的环境中产生的,这一事实使情况变得复杂。本文探讨了针对网络欺凌的常见应对措施的有效性。无论解决网络欺凌的技术工具有多大价值,我们都无法回避这一事实,即这是一个基于社会背景的人际问题。临床意义从业人员应在考虑到网络欺凌的独特性质的同时,以预防和减少面对面欺凌的现有知识为基础。此外,必须考虑到年轻人在社会和学校学习的价值观。
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引用次数: 89
Commissions, coercion and choice 委托、强迫和选择
Pub Date : 2013-05-01 DOI: 10.1192/pb.37.5.179
R. McCutcheon
The recent letter by Das[1][1] was a succinct and clear appraisal of much of the Schizophrenia Commission’s report. Das takes issue with the report’s point that ‘shared decision making on medication choices is essential’, commenting that this cannot refer to ‘the patient with chronic
Das[1][1]最近的信对精神分裂症委员会报告的大部分内容进行了简洁而明确的评价。达斯对报告中“药物选择的共同决策至关重要”的观点提出了质疑,他评论说,这不能指“慢性疾病患者”
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引用次数: 0
期刊
The psychiatrist
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